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Structural Interaction of Apolipoprotein A-I Mimetic Peptide with Amyloid-β Generates Toxic Hetero-oligomers.
The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.
Nanodisc-Forming Scaffold Protein Promoted Retardation of Amyloid-Beta Aggregation.
Polyphosphate Stabilizes Protein Unfolding Intermediates as Soluble Amyloid-like Oligomers.
Derepression of SaPIbov1 Is Independent of φNM1 Type 2 dUTPase Activity and Is Inhibited by dUTP and dUMP.
Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes.
A Potential Structural Switch for Regulating DNA-Binding by TEAD Transcription Factors.
Follow the Yellow Brick Road: A Paradigm Shift in Virus Assembly.
The Type 2 dUTPase of Bacteriophage PdblNM1 Initiates Mobilization of Staphylococcus aureus Bovine Pathogenicity Island 1.
Protein quality control under oxidative stress conditions.
Restoration of NBD1 thermal stability is necessary and sufficient to correct Δf508 CFTR folding and assembly.
E. coli ClpA catalyzed polypeptide translocation is allosterically controlled by the protease ClpP.
Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.
A human TOP2A core DNA binding X-ray structure reveals topoisomerase subunit dynamics and a potential mechanism for SUMO modulation of decatenation.
The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane.
Improved modeling of side-chain-base interactions and plasticity in protein-dna interface design.
Erratum: Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: A member of the phospholipase D superfamily (Journal of Molecular Biology (2012) 415:4 (741-758)).
Molecular structure and peptidoglycan recognition of mycobacterium tuberculosis ArfA (Rv0899).
Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: A member of the phospholipase D superfamily.
The staphylococcus aureus pathogenicity island 1 protein gp6 functions as an internal scaffold during capsid size determination.
Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.
Structural basis for the function of Tim50 in the mitochondrial presequence translocase.
A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assembly..
New approaches for antiviral targeting of HIV assembly..
Activity of E. coli ClpA bound by nucleoside diphosphates and triphosphates.
A conformational switch involved in maturation of staphylococcus aureus bacteriophage 80α capsids.
Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR.
Molecular mechanism of polypeptide translocation catalyzed by the Escherichia coli ClpA Protein Translocase.
Transcriptional Activation of Human Matrix Metalloproteinase-9 Gene Expression by Multiple Co-activators.
Localization of the N-Terminus of Minor Coat Protein IIIa in the Adenovirus Capsid.
Structure of the Myristylated Human Immunodeficiency Virus Type 2 Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Membrane Targeting.
Detection of Intermediates and Kinetic Control during Assembly of Bacteriophage P22 Procapsid.
Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry-based Hydrogen/Deuterium Exchange.
Capsid Size Determination by Staphylococcus aureus Pathogenicity Island SaPI1 Involves Specific Incorporation of SaPI1 Proteins into Procapsids.
Comprehensive Mapping of the C-Terminus of Flap Endonuclease-1 Reveals Distinct Interaction Sites for Five Proteins That Represent Different DNA Replication and Repair Pathways.
Remodeling of the Human Papillomavirus Type 11 Replication Origin into Discrete Nucleoprotein Particles and Looped Structures by the E2 Protein.
Subunit conformations and assembly states of a DNA-translocating motor: the terminase of bacteriophage P22..
Mutation of a Conserved Active Site Residue Converts Tyrosyl-DNA Phosphodiesterase I into a DNA Topoisomerase I-dependent Poison.
Cold-adaptation in Sea-water-borne Signal Proteins: Sequence and NMR Structure of the Pheromone En-6 from the Antarctic Ciliate Euplotes nobilii.
HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions.
Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.
Crystal Structure of Pyruvate Dehydrogenase Phosphatase 1 and its Functional Implications.
Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway.
Identification and Characterization of CMP-NeuAc:GalNAc-IgA1 α2,6-Sialyltransferase in IgA1-producing Cells.
NMR Structure and Functional Characterization of a Human Cancer-related Nucleoside Triphosphatase.
Molecular Dissection of Ø29 Scaffolding Protein Function in an in Vitro Assembly System.
Point Mutations in the HIV-1 Matrix Protein Turn Off the Myristyl Switch.
Analysis of Amino Acids in the β7-β8 Loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase for their Role in Virus Replication.
Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer.
Crystal Structure of Yeast Mitochondrial Peripheral Membrane Protein Tim44p C-terminal Domain.
DNA polymerase X from African swine fever virus: Quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex.
Identification of elements essential for transcription in Brugia malayi promoters.
Energetics of DNA end binding by E. coli RecBC and RecBCD helicases indicate loop formation in the 3′-single-stranded DNA tail.
Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions.
Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough.
Domain study of bacteriophage p22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchange..
The crystal structure of the C-terminal fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40.
Double belt structure of discoidal high density lipoproteins: Molecular basis for size heterogeneity.
Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.
The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.
Effects of temperature and ATP on the kinetic mechanism and kinetic step-size for E. coli RecBCD helicase-catalyzed DNA unwinding.
Fluorescence stopped-flow studies of single turnover kinetics of E. coli RecBCD helicase-catalyzed DNA unwinding.
Erratum: Identification of Novel Interactions in HIV-1 Capsid Protein Assembly by High-resolution Mass Spectrometry (Journal of Molecular Biology (2003) 325 (759-772)).
Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures.
Insights into the catalytic mechanism of cofactor-independent phosphoglycerate mutase from X-ray crystallography, simulated dynamics and molecular modeling.
A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.
Activation of striated muscle: Nearest-neighbor regulatory-unit and cross-bridge influence on myofilament kinetics.
Bacteriophage p22 portal vertex formation in vivo.
Crystal structure of E. coli Hsp100 ClpB nucleotide-binding domain 1 (NBD1) and mechanistic studies on ClpB ATPase activity..
DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies.
Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsids.
Design, characterization, and structure of a biologically active single-chain mutant of human IFN-γ.
Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.
Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopy.
Identification of the C3b binding site in a recombinant vWF-A domain of complement factor B by surface-enhanced laser desorption-ionisation affinity mass spectrometry and homology modelling: Implications for the activity of factor B.
Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide.
The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus phiX174..
The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus φX174 1 1Edited by I. A. Wilson.
Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation..
Crystal structure of ovine interferon-τ at 2.1 Å resolution.
Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
A helical coat protein recognition domain of the bacteriophage P22 scaffolding protein.
Functional domains of bacteriophage P22 scaffolding protein..
The identification and characterization of microsatellites in the compact genome of the Japanese Pufferfish, Fugu rubripes: Perspectives in functional and comparative genomic analyses.
Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase.
Bacteriophage P22 scaffolding protein forms oligomers in solution..
Guanidinobenzoic acid inhibitors of influenza virus neuraminidase.
Assessment of protein fold predictions from sequence information: The predicted α/β doubly wound fold of the von Willebrand factor type a domain is similar to its crystal structure.
Three-dimensional structure of scaffolding-containing phage P22 procapsids by electron cryo-microscopy.
Regulation of codBA operon expression in Escherichia coli by UTP-dependent reiterative transcription and UTP-sensitive transcriptional start site switching..
The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae.
The capsid size-determining protein Sid forms an external scaffold on phage P4 procapsids.
Rescue and replication signals of the adeno-associated virus 2 genome.
An escherichia coli RNA polymerase defective in transcription due to its overproduction of abortive initiation products.
Oxygen radical induced mutagenesis is DNA polymerase specific.
Structural transitions during maturation of bacteriophage lambda capsids..
Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus.
An accurate method for determining the helical repeat of DNA in solution reveals differences to the crystal structures of two B-DNA decamers.
Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.
Scaffolding protein regulates the polymerization of P22 coat subunits into icosahedral shells in vitro..
Alterations in DNA helix stability due to base modifications can be evaluated using denaturing gradient gel electrophoresis.
Regulation of α operon gene expression in Escherichia coli. A novel form of translational coupling.
Increased expression of ribosomal genes during inhibition of ribosome assembly in Escherichia coli.
Oligomeric structure of a simian virus 40 T antigen in free form and bound to DNA.
Incomplete splicing and deficient accumulation of the fiber messenger RNA in monkey cells infected by human adenovirus type 2.
Interpretations of the effects of pH on the spectra of purple membrane.
Complex splicing patterns of RNAs from the early regions of adenovirus-2.
Electron microscopic characterization of DNAs of non-defective deletion mutants of bacteriophage Mu.
Sequence arrangements of the Escherichia coli chromosome and of putative insertion sequences, as revealed by electron microscopic heteroduplex studies.
Underwound loops in self-renatured DNA can be diagnostic of inverted duplications and translocated sequences.
Electron microscope study of the structures of λdv DNAs.
Electron microscope mapping of the distribution of ribosomal genes of the Bacillus subtilis chromosome.
Electron microscope study of the structures of the Bacillus subtilis prophages, SPO2 and φ105.
Map of the partial sequence homology between DNA molecules of Bacillus subtilis bacteriophages SPO2 and φ105.
The sequence of gene product interaction in bacteriophage T4 tail core assembly.