Journal of Molecular Biology

Journal

Publication Venue For

  • Structural Interaction of Apolipoprotein A-I Mimetic Peptide with Amyloid-β Generates Toxic Hetero-oligomers.  432:1020-1034. 2020
  • The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.  431:1440-1459. 2019
  • Nanodisc-Forming Scaffold Protein Promoted Retardation of Amyloid-Beta Aggregation.  430:4230-4244. 2018
  • Polyphosphate Stabilizes Protein Unfolding Intermediates as Soluble Amyloid-like Oligomers.  430:4195-4208. 2018
  • Derepression of SaPIbov1 Is Independent of φNM1 Type 2 dUTPase Activity and Is Inhibited by dUTP and dUMP.  429:1570-1580. 2017
  • Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes.  428:4905-4916. 2016
  • A Potential Structural Switch for Regulating DNA-Binding by TEAD Transcription Factors.  428:2557-2568. 2016
  • A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila.  428:2446-2461. 2016
  • Follow the Yellow Brick Road: A Paradigm Shift in Virus Assembly.  428:416-418. 2016
  • The Type 2 dUTPase of Bacteriophage PdblNM1 Initiates Mobilization of Staphylococcus aureus Bovine Pathogenicity Island 1.  428:142-152. 2016
  • Protein quality control under oxidative stress conditions.  427:1549-1563. 2015
  • Restoration of NBD1 thermal stability is necessary and sufficient to correct Δf508 CFTR folding and assembly.  427:106-120. 2015
  • E. coli ClpA catalyzed polypeptide translocation is allosterically controlled by the protease ClpP.  425:2795-2812. 2013
  • Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.  425:812-829. 2013
  • A human TOP2A core DNA binding X-ray structure reveals topoisomerase subunit dynamics and a potential mechanism for SUMO modulation of decatenation.  424:105-108. 2012
  • The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane.  421:348-363. 2012
  • Improved modeling of side-chain-base interactions and plasticity in protein-dna interface design.  419:255-274. 2012
  • Erratum: Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: A member of the phospholipase D superfamily (Journal of Molecular Biology (2012) 415:4 (741-758)).  416:725. 2012
  • Alternative Relay and Converter Domains Tune Native Muscle Myosin Isoform Function in Drosophila.  416:543-557. 2012
  • Molecular structure and peptidoglycan recognition of mycobacterium tuberculosis ArfA (Rv0899).  416:208-220. 2012
  • Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: A member of the phospholipase D superfamily.  415:741-758. 2012
  • The staphylococcus aureus pathogenicity island 1 protein gp6 functions as an internal scaffold during capsid size determination.  412:710-722. 2011
  • Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.  412:94-110. 2011
  • A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assembly..  410:641-652. 2011
  • New approaches for antiviral targeting of HIV assembly..  410:634-640. 2011
  • Activity of E. coli ClpA bound by nucleoside diphosphates and triphosphates.  409:333-347. 2011
  • A conformational switch involved in maturation of staphylococcus aureus bacteriophage 80α capsids.  405:863-876. 2011
  • Mutating the Converter–Relay Interface of Drosophila Myosin Perturbs ATPase Activity, Actin Motility, Myofibril Stability and Flight Ability.  398:625-632. 2010
  • Molecular mechanism of polypeptide translocation catalyzed by the Escherichia coli ClpA Protein Translocase.  399:665-679. 2010
  • Alternative Exon 9-Encoded Relay Domains Affect More than One Communication Pathway in the Drosophila Myosin Head.  389:707-721. 2009
  • Transcriptional Activation of Human Matrix Metalloproteinase-9 Gene Expression by Multiple Co-activators.  383:945-956. 2008
  • Localization of the N-Terminus of Minor Coat Protein IIIa in the Adenovirus Capsid.  383:923-934. 2008
  • Structure of the Myristylated Human Immunodeficiency Virus Type 2 Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Membrane Targeting.  382:434-447. 2008
  • Detection of Intermediates and Kinetic Control during Assembly of Bacteriophage P22 Procapsid.  381:1395-1406. 2008
  • Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry-based Hydrogen/Deuterium Exchange.  381:772-784. 2008
  • Capsid Size Determination by Staphylococcus aureus Pathogenicity Island SaPI1 Involves Specific Incorporation of SaPI1 Proteins into Procapsids.  380:465-475. 2008
  • Comprehensive Mapping of the C-Terminus of Flap Endonuclease-1 Reveals Distinct Interaction Sites for Five Proteins That Represent Different DNA Replication and Repair Pathways.  377:679-690. 2008
  • Remodeling of the Human Papillomavirus Type 11 Replication Origin into Discrete Nucleoprotein Particles and Looped Structures by the E2 Protein.  375:1165-1177. 2008
  • Subunit conformations and assembly states of a DNA-translocating motor: the terminase of bacteriophage P22..  374:817-836. 2007
  • Mutation of a Conserved Active Site Residue Converts Tyrosyl-DNA Phosphodiesterase I into a DNA Topoisomerase I-dependent Poison.  372:1070-1081. 2007
  • Cold-adaptation in Sea-water-borne Signal Proteins: Sequence and NMR Structure of the Pheromone En-6 from the Antarctic Ciliate Euplotes nobilii.  372:277-286. 2007
  • HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions.  372:369-381. 2007
  • Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.  370:701-713. 2007
  • Crystal Structure of Pyruvate Dehydrogenase Phosphatase 1 and its Functional Implications.  370:417-426. 2007
  • Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway.  369:619-630. 2007
  • Identification and Characterization of CMP-NeuAc:GalNAc-IgA1 α2,6-Sialyltransferase in IgA1-producing Cells.  369:69-78. 2007
  • NMR Structure and Functional Characterization of a Human Cancer-related Nucleoside Triphosphatase.  367:788-801. 2007
  • Molecular Dissection of Ø29 Scaffolding Protein Function in an in Vitro Assembly System.  366:1161-1173. 2007
  • Point Mutations in the HIV-1 Matrix Protein Turn Off the Myristyl Switch.  366:574-585. 2007
  • Analysis of Amino Acids in the β7-β8 Loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase for their Role in Virus Replication.  365:1368-1378. 2007
  • Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer.  364:248-258. 2006
  • αB-Crystallin Maintains Skeletal Muscle Myosin Enzymatic Activity and Prevents its Aggregation under Heat-shock Stress.  358:635-645. 2006
  • DNA polymerase X from African swine fever virus: Quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex.  356:121-141. 2006
  • Identification of elements essential for transcription in Brugia malayi promoters.  353:1-13. 2005
  • Energetics of DNA end binding by E. coli RecBC and RecBCD helicases indicate loop formation in the 3′-single-stranded DNA tail.  352:765-782. 2005
  • Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions.  349:673-684. 2005
  • Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough.  348:801-815. 2005
  • Domain study of bacteriophage p22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchange..  347:935-948. 2005
  • Double belt structure of discoidal high density lipoproteins: Molecular basis for size heterogeneity.  343:1293-1311. 2004
  • Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.  342:953-970. 2004
  • The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.  342:503-514. 2004
  • Effects of temperature and ATP on the kinetic mechanism and kinetic step-size for E. coli RecBCD helicase-catalyzed DNA unwinding.  339:751-771. 2004
  • Fluorescence stopped-flow studies of single turnover kinetics of E. coli RecBCD helicase-catalyzed DNA unwinding.  339:731-750. 2004
  • Erratum: Identification of Novel Interactions in HIV-1 Capsid Protein Assembly by High-resolution Mass Spectrometry (Journal of Molecular Biology (2003) 325 (759-772)).  334:1133. 2003
  • Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures.  334:733-749. 2003
  • Insights into the catalytic mechanism of cofactor-independent phosphoglycerate mutase from X-ray crystallography, simulated dynamics and molecular modeling.  328:909-920. 2003
  • A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.  328:131-146. 2003
  • Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.  325:759-772. 2003
  • Activation of striated muscle: Nearest-neighbor regulatory-unit and cross-bridge influence on myofilament kinetics.  322:1065-1088. 2002
  • Bacteriophage p22 portal vertex formation in vivo.  315:975-994. 2002
  • DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies.  324:409-428. 2002
  • Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsids.  306:389-396. 2001
  • Design, characterization, and structure of a biologically active single-chain mutant of human IFN-γ.  299:169-179. 2000
  • Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.  297:1195-1202. 2000
  • Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopy.  297:615-626. 2000
  • Identification of the C3b binding site in a recombinant vWF-A domain of complement factor B by surface-enhanced laser desorption-ionisation affinity mass spectrometry and homology modelling: Implications for the activity of factor B.  294:587-599. 1999
  • Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.  293:1107-1119. 1999
  • Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide.  292:361-373. 1999
  • The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus phiX174..  288:595-608. 1999
  • The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus φX174 1 1Edited by I. A. Wilson.  288:595-608. 1999
  • Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation..  287:527-538. 1999
  • Crystal structure of ovine interferon-τ at 2.1 Å resolution.  286:151-162. 1999
  • Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.  281:285-299. 1998
  • A helical coat protein recognition domain of the bacteriophage P22 scaffolding protein.  281:81-94. 1998
  • Functional domains of bacteriophage P22 scaffolding protein..  281:69-79. 1998
  • The identification and characterization of microsatellites in the compact genome of the Japanese Pufferfish, Fugu rubripes: Perspectives in functional and comparative genomic analyses.  278:843-854. 1998
  • Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase.  269:494-504. 1997
  • Bacteriophage P22 scaffolding protein forms oligomers in solution..  268:655-665. 1997
  • Guanidinobenzoic acid inhibitors of influenza virus neuraminidase.  267:584-594. 1997
  • Assessment of protein fold predictions from sequence information: The predicted α/β doubly wound fold of the von Willebrand factor type a domain is similar to its crystal structure.  260:277-285. 1996
  • Three-dimensional structure of scaffolding-containing phage P22 procapsids by electron cryo-microscopy.  260:85-98. 1996
  • Regulation of codBA operon expression in Escherichia coli by UTP-dependent reiterative transcription and UTP-sensitive transcriptional start site switching..  254:552-565. 1995
  • The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae.  251:334-345. 1995
  • The capsid size-determining protein Sid forms an external scaffold on phage P4 procapsids.  251:59-75. 1995
  • Rescue and replication signals of the adeno-associated virus 2 genome.  250:573-580. 1995
  • An escherichia coli RNA polymerase defective in transcription due to its overproduction of abortive initiation products.  236:72-80. 1994
  • Oxygen radical induced mutagenesis is DNA polymerase specific.  235:33-41. 1994
  • Structural transitions during maturation of bacteriophage lambda capsids..  233:682-694. 1993
  • Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus.  231:65-74. 1993
  • An accurate method for determining the helical repeat of DNA in solution reveals differences to the crystal structures of two B-DNA decamers.  228:322-326. 1992
  • Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.  224:1075-1085. 1992
  • Scaffolding protein regulates the polymerization of P22 coat subunits into icosahedral shells in vitro..  202:743-757. 1988
  • Alterations in DNA helix stability due to base modifications can be evaluated using denaturing gradient gel electrophoresis.  198:737-744. 1987
  • Regulation of α operon gene expression in Escherichia coli. A novel form of translational coupling.  196:333-345. 1987
  • Increased expression of ribosomal genes during inhibition of ribosome assembly in Escherichia coli.  184:23-30. 1985
  • Oligomeric structure of a simian virus 40 T antigen in free form and bound to DNA.  148:347-353. 1981
  • Incomplete splicing and deficient accumulation of the fiber messenger RNA in monkey cells infected by human adenovirus type 2.  139:221-242. 1980
  • Interpretations of the effects of pH on the spectra of purple membrane.  135:595-609. 1979
  • Complex splicing patterns of RNAs from the early regions of adenovirus-2.  134:265-303. 1979
  • Electron microscopic characterization of DNAs of non-defective deletion mutants of bacteriophage Mu.  113:591-609. 1977
  • Sequence arrangements of the Escherichia coli chromosome and of putative insertion sequences, as revealed by electron microscopic heteroduplex studies.  113:611-621. 1977
  • Underwound loops in self-renatured DNA can be diagnostic of inverted duplications and translocated sequences.  113:579-589. 1977
  • Electron microscope study of the structures of λdv DNAs.  86. 1974
  • Electron microscope mapping of the distribution of ribosomal genes of the Bacillus subtilis chromosome.  75. 1973
  • Electron microscope study of the structures of the Bacillus subtilis prophages, SPO2 and φ105.  75. 1973
  • Map of the partial sequence homology between DNA molecules of Bacillus subtilis bacteriophages SPO2 and φ105.  68. 1972
  • The sequence of gene product interaction in bacteriophage T4 tail core assembly.  58:685-692. 1971
  • International Standard Serial Number (issn)

  • 0022-2836
  • Electronic International Standard Serial Number (eissn)

  • 1089-8638