Journal of Clinical Investigation

HLA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection. 2021

Healing and repair after myocardial infarction: The forgotten but resurgent basophil.  131. 2021

Rectal and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge. 2021

DACH1 as a multifaceted and potentially druggable susceptibility factor for kidney disease.  131. 2021

Tissue-resident-like CD4⁺ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung.  131. 2021

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.  131. 2021

N-cadherin upregulation mediates adaptive radioresistance in glioblastoma.  131. 2021

Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.  131. 2021

Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection.  131. 2021

Erratum: Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2 (Journal of Clinical Investigation (2017) 127:8 (3075-3089) DOI: 10.1172/JCI89092).  130:6187. 2020

Erratum: Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2 (The Journal of clinical investigation PII: 142404).  130:5027. 2020

Tentonin 3 as a baroreceptor mechanosensor: Not a stretch.  130:3412-3415. 2020

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.  130:214-230. 2020

Slowing ribosome velocity restores folding and function of mutant CFTR.  129:5236-5253. 2019

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.  129:4769-4785. 2019

Increased flux through the mevalonate pathway mediates fibrotic repair without injury.  129:4962-4978. 2019

Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease.  129:4506-4522. 2019

Revealing the molecular signaling pathways of mucus stasis in cystic fibrosis.  129:4089-4090. 2019

Apolipoprotein A-I mimetics mitigate intestinal inflammation in a COX2-dependent inflammatory disease model.  129:3670-3685. 2019

Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.  129:3407-3419. 2019

Blinded by the light: A nonhuman primate model of achromatopsia.  129:513-515. 2019

An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.  129. 2019

Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury.  129:2792-2806. 2019

SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.  129:2685-2701. 2019

Airway fractal dimension predicts respiratory morbidity and mortality in COPD.  128:5374-5382. 2018

Erratum: Airway fractal dimension predicts respiratory morbidity and mortality in COPD (Journal of Clinical Investigation (2018) 128:12 (5374–5382) DOI: 10.1172/JCI120693).  128:5676. 2018

HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers.  128:4074-4085. 2018

HIV-1 latent reservoir size and diversity are stable following brief treatment interruption.  128:3102-3115. 2018

Neuronal hypothalamic regulation of body metabolism and bone density is galanin dependent.  128:2626-2641. 2018

Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response.  128:2356-2369. 2018

STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion.  128:1867-1872. 2018

Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance.  128:309-322. 2018

Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma.  128:294-308. 2018

Epiregulin and EGFR interactions are involved in pain processing.  127:3353-3366. 2017

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.  127:3075-3089. 2017

Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.  127:2262-2276. 2017

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.  127:2392-2406. 2017

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.  127:1798-1812. 2017

BCL-W has a fundamental role in B cell survival and lymphomagenesis.  127:635-650. 2017

Overcoming therapeutic resistance in glioblastoma: The way forward.  127:415-426. 2017

LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.  127:215-229. 2017

NLRC4 suppresses melanoma tumor progression independently of inflammasome activation.  126:3917-3928. 2016

A colitogenic memory CD4⁺ T cell population mediates gastrointestinal graft-versus-host disease.  126:3541-3555. 2016

Bioactive extracellular matrix fragments in lung health and disease.  126:3176-3184. 2016

Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.  126:3336-3350. 2016

PKCδ-targeted intervention relieves chronic pain in a murine sickle cell disease model.  126:3053-3057. 2016

LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors.  126:1267-1281. 2016

Heterogeneity of leukemia-initiating capacity of chronic myelogenous leukemia stem cells.  126:975-991. 2016

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells.  125:4077-4090. 2015

Rescuing the physician-scientist workforce: The time for action is now.  125:3742-3747. 2015

Mouse and primate lifespan is correlated with immunoproteasome expression 2015

BAI1 regulates spatial learning and synaptic plasticity in the hippocampus.  125:1497-1508. 2015

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.  125:521-538. 2015

Exploiting metabolic and antioxidant pathways to maintain vision in blinding disease.  125:1390-1392. 2015

Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus.  125:2877-2890. 2015

Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1.  124:3455-3468. 2014

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.  124:2861-2876. 2014

Missense dopamine transporter mutations associate with adult parkinsonism and ADHD.  124:3107-3120. 2014

MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.  124:2651-2667. 2014

The genetics and immunobiology of IgA nephropathy.  124:2325-2332. 2014

SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome.  124:1512-1524. 2014

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.  124:981-999. 2014

B cells mediate chronic allograft rejection independently of antibody production.  124:1052-1056. 2014

Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.  124:553-563. 2014

Fibrosis: Ultimate and proximate causes.  124:4673-4677. 2014

Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.  123:5319-5333. 2013

Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma.  123:4786-4798. 2013

Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration.  123:4525-4539. 2013

PP2A-activating drugs selectively eradicate tki-resistant chronic myeloid leukemic stem cells.  123:4144-4157. 2013

Proximal tubule h-ferritin mediates iron trafficking in acute kidney injury.  123:4423-4434. 2013

ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling.  123:3243-3253. 2013

Atrial natriuretic peptide is negatively regulated by microRNA-425.  123:3378-3382. 2013

HIF1α and HIF2α independently activate SRC to promote melanoma metastases.  123:2078-2093. 2013

MERTK receptor tyrosine kinase is a therapeutic target in melanoma.  123:2257-2267. 2013

GSK-3α is a central regulator of age-related pathologies in mice.  123:1821-1832. 2013

Amelioration of arthritis through mobilization of peptide-specific CD8 ⁺ regulatory T cells.  123:1382-1389. 2013

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis.  123:1096-1108. 2013

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.  123:712-726. 2013

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair.  123:443-454. 2013

P62 Links β-adrenergic input to mitochondrial function and thermogenesis.  123:469-478. 2013

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes.  122:4401-4411. 2012

Hypoxic pulmonary vasoconstriction requires connexin 40-mediated endothelial signal conduction.  122:4218-4230. 2012

Mesodermal Pten inactivation leads to alveolar capillary dysplasia-like phenotype.  122:3862-3872. 2012

Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity.  122:3769-3780. 2012

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.  122:2807-2816. 2012

Fungal antioxidant pathways promote survival against neutrophils during infection.  122:2482-2498. 2012

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury.  122:2661-2671. 2012

Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model.  122:1777-1785. 2012

Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.  122:1907-1919. 2012

P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.  122:1283-1295. 2012

Erratum: CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (The Journal of Clinical Investigation (2011) 121, 10, (3965-3980) DOI: 10.1172/JCI58552).  122:780. 2012

Erratum: Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy (Journal of Clinical Investigation (2011) 121, 10 (3991-4002) DOI: 10.1172/JCI45563).  122:778. 2012

Erratum: Synaptopodin regulates the actin-bundling activity of a-actinin in an isoform-specific manner (Journal of Clinical Investigation (2005) 115, 5, (1188-1198) DOI: 10.1172/JCI23371).  122:781. 2012

FGF23 induces left ventricular hypertrophy.  121:4393-4408. 2011

Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.  121:4409-4419. 2011

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.  121:3965-3980. 2011

Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy.  121:3991-4002. 2011

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice.  121:4003-4014. 2011

Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis.  121:3517-3527. 2011

Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8 - Mediated activation of TGF-β.  121:2863-2875. 2011

The LRF transcription factor regulates mature B cell development and the germinal center response in mice.  121:2583-2598. 2011

Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice.  121:2169-2180. 2011

The human visual cortex responds to gene therapy-mediated recovery of retinal function.  121:2160-2168. 2011

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.  121:2013-2024. 2011

Erratum: Lighting a candle in the dark: Advances in genetics and gene therapy of recessive retinal dystrophies (Journal of Clinical Investigation (2010) 120, 9 (3042-3053) DOI: 10.1172/JCI42258).  121:456. 2011

Erratum: The human visual cortex responds to gene therapy-mediated recovery of retinal function (The Journal of Clinical Investigation (2011) 121, 6, (2160-2168) DOI: 10.1172/JCI57377).  121:2945. 2011

Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties.  120:4532-4545. 2010

Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice.  120:4007-4020. 2010

Lighting a candle in the dark: Advances in genetics and gene therapy of recessive retinal dystrophies.  120:3042-3053. 2010

GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice.  120:2280-2291. 2010

A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates.  120:1125-1139. 2010

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease.  120:627-635. 2010

Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.  119:1668-1677. 2009

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models.  119:1638-1646. 2009

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.  119:1124-1135. 2009

Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans.  119:911-923. 2009

Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice.  118:1955-1964. 2008

Erythropoietin: When liability becomes asset in neurovascular repair.  118:467-470. 2008

IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.  118:629-639. 2008

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.  117:3753-3764. 2007

A nervous breakdown in the skin: Stress and the epidermal barrier.  117:3166-3169. 2007

LAG-3 regulates CD8⁺ T cell accumulation and effector function in murine self- and tumor-tolerance systems.  117:3383-3392. 2007

Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation.  117:2583-2591. 2007

An erythroid chaperone that facilitates folding of α-globin subunits for hemoglobin synthesis.  117:1856-1865. 2007

The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development.  117:1616-1626. 2007

Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis.  116:3183-3194. 2006

Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.  116:536-547. 2006

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control.  115:2099-2107. 2005

Synaptopodin regulates the actin-bundling activity of α-actinin in an isoform-specific manner.  115:1188-1198. 2005

IL-1 mediates TNF-induced osteoclastogenesis.  115:282-290. 2005

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver.  115:1232-1240. 2005

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity.  115:66-75. 2005

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity..  115:66-75. 2005

Bacterial flagellin is a dominant antigen in Crohn disease.  113:1296-1306. 2004

Blockade of T cell costimulation reveals interrelated actions of CD4 ⁺ and CD8⁺ T cells in control of SIV replication.  113:836-845. 2004

Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1^+/- mice.  113:867-875. 2004

Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation..  113:609-618. 2004

Induction of B7-1 in podocytes is associated with nephrotic syndrome.  113:1390-1397. 2004

The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signaling.  114:206-213. 2004

Do allelic variants of SLC6A14 predispose to obesity?.  112:1633-1636. 2003

Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior..  112:1895-1905. 2003

CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis.  112:1332-1341. 2003

CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis..  112:1332-1341. 2003

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.  112:1244-1254. 2003

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load..  112:1244-1254. 2003

Luminal NaCl delivery regulates basolateral PGE2 release from macula densa cells.  112:76-82. 2003

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse..  111:1783-1791. 2003

Erratum: Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice (Journal of Clinical Investigation (2003) 111 (445-452)).  111:1259. 2003

Erratum: Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice (Journal of Clinical Investigation (2003) 111 (445-452)).  111:1259. 2003

The role of uncoupling protein 3 in human physiology.  111:438-441. 2003

The role of uncoupling protein 3 in human physiology..  111:438-441. 2003

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.  111:445-452. 2003

Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior.  112:1895-1905. 2003

The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone.  111:1021-1028. 2003

The role of uncoupling protein 3 in human physiology.  111:438-441. 2003

The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.  111:1783-1791. 2003

Herpes simplex viruses: is a vaccine tenable?.  110:145-151. 2002

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease..  109:533-540. 2002

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease.  109:533-540. 2002

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease.  109:533-540. 2002

Herpes simplex viruses: Is a vaccine tenable?.  110:145-151. 2002

Regulation of herpes simplex virus γ134.5 expression and oncolysis of diffuse liver metastases by Myb34.5.  109:871-882. 2002

Thymic dendritic cells traffic to thymi of allogeneic recipients and prolong graft survival.  109:755-764. 2002

Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.  108:1621-1629. 2001

Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells..  108:1657-1665. 2001

Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration..  108:1759-1770. 2001

A Glanzmann's mutation in beta 3 integrin specifically impairs osteoclast function..  107:1137-1144. 2001

Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells.  108:1657-1665. 2001

TGF-β is a critical mediator of acute lung injury.  107:1537-1544. 2001

The de-adhesive activity of matricellular proteins: Is intermediate cell adhesion an adaptive state?.  107:785-790. 2001

Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts..  105:433-440. 2000

Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice.  105:813-821. 2000

C-reactive protein binding to FcγRIIa on human monocytes and neutrophils is allele-specific.  105:369-376. 2000

Immune recognition of OxLDL in atherosclerosis.  105:1683-1685. 2000

β3-adrenoceptor deficiency blocks nitric oxide-dependent inhibition of myocardial contractility.  106:697-703. 2000

Defects of T-cell effector function and post-thymic maturation in X- linked hyper-IgM syndrome.  103:1151-1158. 1999

Accessory factors and the regulation of epithelial sodium channel activity.  103:593. 1999

Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies.  104:73-81. 1999

Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation.  104:1021-1029. 1999

Epithelial P2X purinergic receptor channel expression and function.  104:875-884. 1999

αENaC: Leading the charge.  104:849-850. 1999

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.  102:1515-1525. 1998

Apoptosis mediated by Fas but not tumor necrosis factor receptor 1 prevents chronic disease in mice infected with murine cytomegalovirus.  102:1431-1443. 1998

Effects of mutations in the human uncoupling protein 3 gene on the respiratory quotient and fat oxidation in severe obesity and type 2 diabetes.  102:1345-1351. 1998

Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat.  102:445-454. 1998

Defective expression of p561ck in an infant with severe combined immunodeficiency.  102:421-429. 1998

Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance.  101:2377-2386. 1998

An autosomal genomic scan for loci linked to prediabetic phenotypes in pima indians.  101:1757-1764. 1998

The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants.  101:1745-1756. 1998

Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.  101:935-939. 1998

Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias: Acute regulation of CFTR trafficking in an intact epithelium.  101:737-745. 1998

Angiotensin II stimulates proliferation of normal early erythroid progenitors.  100:2310-2314. 1997

A novel polymorphism of FcγRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.  100:1059-1070. 1997

Compartmentalization of angiotensin II generation in the dog heart: Evidence for independent mechanisms in intravascular and interstitial spaces.  100:253-258. 1997

Autoimmunity caused by disruption of central T cell tolerance. A murine model of drug-induced lupus.  99:1888-1896. 1997

Fas ligand expression by astrocytoma in vivo: Maintaining immune privilege in the brain?.  99:1173-1178. 1997

Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines.  99:926-936. 1997

Localization of a single binding site for immunoglobulin light chains on human Tamm-Horsfall glycoprotein.  99:732-736. 1997

Atrial natriuretic peptide regulation of noradrenaline release in the anterior hypothalamic area of spontaneously hypertensive rats.  98:2060-2065. 1996

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.  98:1107-1113. 1996

T cell receptor biases and clonal proliferations among lung transplant recipients with obliterative bronchiolitis.  97:2642-2650. 1996

Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans..  97:1348-1354. 1996

FcγRIIA alleles are heritable risk factors for lupus nephritis in African Americans.  97:1348-1354. 1996

The expression of TNFα by human muscle: Relationship to insulin resistance.  97:1111-1116. 1996

Murine Vλx and Vλx-containing antibodies bind human myelin basic protein.  97:486-492. 1996

Gene modification via 'plug and socket' gene targeting.  98. 1996

Sticky business: cytoskeleton and Na+ transport..  97:2691. 1996

Fc gamma receptor IIIb enhances Fc gamma receptor IIa function in an oxidant-dependent and allele-sensitive manner..  95:2877-2885. 1995

Fcγ receptor IIIb enhances Fcγ receptor IIa function in an oxidant-dependent and allele-sensitive manner.  95:2877-2885. 1995

Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle: Implications for glucose toxicity.  96:2792-2801. 1995

Metabolic Predictors of Obesity: Contribution of Resting Energy Expenditure, Thermic Effect of Food, and Fuel Utilization to Four-year Weight Gain of Post-obese and Never-obese Women.  95:980-985. 1995

Somatic mutation and CDR3 lengths of immunoglobulin κ light chains expressed in patients with rheumatoid arthritis and in normal individuals.  96:831-841. 1995

Targeted tumor killing via an intracellular antibody against erbB-2.  96:2980-2989. 1995

Treatment of marrow stroma with interferon-α restores normal β1 integrin-dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors: Role of MIP-1α.  96:931-939. 1995

Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide binding.  94:228-236. 1994

Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis.  93:361-370. 1994

Interferon-α restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired β1 integrin receptor function.  94:384-391. 1994

Localization of cystic fibrosis transmembrane conductance regulator mRNA in the human gastrointestinal tract by in situ hybridization.  93:347-354. 1994

Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro.  93:26-32. 1994

Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.  94:2407-2413. 1994

Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats.  94:663-671. 1994

Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.  94:1698-1705. 1994

A novel superantigen isolated from pathogenic strains of Streptococcus pyogenes with aminoterminal homology to staphylococcal enterotoxins B and C.  92:710-719. 1993

Bence Jones proteins bind to a common peptide segment of Tamm-Horsfall glycoprotein to promote heterotypic aggregation.  92:2975-2983. 1993

Bioenergetic abnormalities associated with severe left ventricular hypertrophy.  92:993-1003. 1993

Definition of immunoglobulin A receptors on eosinophils and their enhanced expression in allergic individuals.  92:1681-1685. 1993

Hyperthermia induces expression of transforming growth factor-βs in rat cardiac cells in vitro and in vivo.  92:404-410. 1993

IL-1-induced murine osteoblast IL-6 production is mediated by the type 1 IL-1 receptor and is increased by 1,25 dihydroxyvitamin D3.  91:1731-1742. 1993

Intravenous IgG: Supertherapy for superantigens?.  91:378. 1993

Pseudomonas aeruginosa-induced lung and pleural injury in sheep. Differential protective effect of circulating versus alveolar immunoglobulin G antibody.  92:1221-1228. 1993

Replication, establishment of latency, and induced reactivation of herpes simplex virus γ1 34.5 deletion mutants in rodent models.  91:2837-2843. 1993

Allelic polymorphisms of human Fcγ receptor IIA and Fcγ receptor IIIB: Independent mechanisms for differences in human phagocyte function.  89:1274-1281. 1992

Cytomegalovirus induction of tumor necrosis factor-α by human monocytes and mucosal macrophages.  90:1642-1648. 1992

Major histocompatibility complex class III genes and susceptibility to immunoglobulin a deficiency and common variable immunodeficiency.  89:1914-1922. 1992

Novel Fcγ receptor I family gene products in human mononuclear cells.  90:2102-2109. 1992

Pathobiology of cast nephropathy from human Bence Jones proteins.  89:630-639. 1992

Role of transforming growth factor-β in maintenance of function of cultured neonatal cardiac myocytes. Autocrine action and reversal of damaging effects of interleukin-1.  90:2056-2062. 1992

Ultraviolet-irradiated monocytes efficiently inhibit the intracellular replication of mycobacterium avium intracellulare.  89:1282-1287. 1992

An idiotypic marker associated with a germ-line encoded κ light chain variable region that predominates the vaccine-induced human antibody response to the Haemophilus influenzae b polysaccharide.  88:1811-1818. 1991

Human appendix B cells naturally express receptors for and respond to interleukin 6 with selective IgA1 and IgA2 synthesis.  88:248-252. 1991

Immunoregulation in onchocerciasis: Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapy.  88:231-238. 1991

In search of Mr. Wizard. Presidential address to the American Society for Clinical Investigation, Seattle, Washington, 4 May 1991.  88:1063-1066. 1991

L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.  88:1559-1567. 1991

Preferential expression of human FcγRIII(PMN) (CD16) in paroxysmal nocturnal hemoglobinuria. Discordant expression of glycosyl phosphatidylinositol-linked proteins.  87:58-67. 1991

Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity.  87:1072-1081. 1991

Soluble surface proteins from Helicobacter pylori activate monocytes/macrophages by lipopolysaccharide-independent mechanism.  87:894-900. 1991

Fc gamma receptor III on human neutrophils. Allelic variants have functionally distinct capacities..  85:1287-1295. 1990

Abnormal cardiac function in the streptozotocin-diabetic rat: Changes in active and passive properties of the left ventricle.  86:481-488. 1990

Apolipoprotein A-I and its amphipathic helix peptide analogues inhibit human immunodeficiency virus-induced syncytium formation.  86:1142-1150. 1990

Atrial natriuretic peptide attenuates the development of pulmonary hypertension in rats adapted to chronic hypoxia.  85:115-120. 1990

Blockade of endogenous anterior hypothalamic atrial natriuretic peptide with monoclonal antibody lowers blood pressure in spontaneously hypertensive rats.  86:1985-1990. 1990

Cell membrane is a major locus for ultraviolet B-induced alterations in accessory cells.  85:1529-1536. 1990

Expression of interleukin 2 receptors by monocytes from patients with acquired immunodeficiency syndrome and induction of monocyte interleukin 2 receptors by human immunodeficiency virus in vitro.  85:192-199. 1990

Fcγ receptor III on human neutrophils: Allelic variants have functionally distinct capacities.  85:1287-1295. 1990

Mechanisms of intranephronal proteinaceous cast formation by low molecular weight proteins.  85:570-576. 1990

Recombinant latent transforming growth factor β1 has a longer plasma half-life in rats than active transforming growth factor β1, and a different tissue distribution.  86:1976-1984. 1990

A novel mechanism for the generation of superoxide anions in hematoporphyrin derivative-mediated cutaneous photosensitization. Activation of the xanthine oxidase pathway.  83:1137-1143. 1989

Clustering of multiallele DNA markers near the Huntington's disease gene.  84:1013-1016. 1989

In vivo handling of soluble complement fixing Ab/dsDNA immune complexes in chimpanzees.  84:962-970. 1989

Prostaglandin E2 selectively increases interferon gamma receptor expression on human CD8⁺ lymphocytes.  83:1436-1440. 1989

Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic area.  83:14-22. 1989

Tolerance induced by physiological levels of secreted proteins in transgenic mice expressing human insulin.  84:1550-1554. 1989

Differential nephrotoxicity of low molecular weight proteins including Bence Jones proteins in the perfused rat nephron in vivo.  82:2086-2096. 1988

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.  81:47-51. 1988

Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus.  81:1528-1536. 1988

Defective antigen presentation and novel structural properties of DR1 from an HLA haplotype associated with 21-hydroxylase deficiency.  80:998-1008. 1987

Human adipocyte glucose transport system. Biochemical and functional heterogeneity of hexose carriers.  79:703-709. 1987

Parallel adaptation of the rabbit renal cortical sodium/proton antiporter and sodium/bicarbonate cotransporter in metabolic acidosis and alkalosis..  80:308-315. 1987

Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow.  80:905-910. 1987

Age-related normalization of the browning rate of collagen in diabetic subjects without retinopathy.  78:832-835. 1986

Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathies.  77:1931-1938. 1986

Electrogenic sodium/bicarbonate cotransport in rabbit renal cortical basolateral membrane vesicles.  78:1472-1478. 1986

Human complement protein D catabolism by the rat kidney.  77:1299-1304. 1986

Laminin promotes rabbit neutrophil motility and attachment.  77:1180-1186. 1986

Proliferative signals for suppressor T cells. Helper cells stimulated with pokeweed mitogen in vitro produce a suppressor cell growth factor.  78:214-220. 1986

Bacillus Calmette-Guerin-stimulated neutrophils release chemotaxis for monocytes in rabbit pleural spaces and in vitro.  76:1514-1521. 1985

Expression of complement proteins C2 and factor B in transfected L cells.  76:1449-1454. 1985

Insulin receptor down-regulation is linked to an insulin-induced postreceptor defect in the glucose transport system in rat adipocytes.  76:22-30. 1985

Catabolism of very low density lipoproteins in experimental nephrosis.  74:1375-1383. 1984

Monocyte function in the acquired immune deficiency syndrome. Defective chemotaxis.  74:2121-2128. 1984

Volume-independent reductions in glomerular filtration rate in acute chloride-depletion alkalosis in the rat. Evidence for mediation by tubuloglomerular feedback.  74:2002-2008. 1984

Suppression of in vitro monoclonal human rheumatoid factor synthesis by antiidiotypic antibody. Target cells and molecular requirements.  72:1410-1419. 1983

Decrease in peripheral sympathetic nervous system activity following renal denervation or unclipping in the one-kidney one-clip Goldblatt hypertensive rat.  69:55-62. 1982

Chloride uptake by brush border membrane vesicles isolated from rabbit renal cortex. Coupling to proton gradients and K⁺ diffusion potentials.  67:103-115. 1981

Postnatal physiologic hypercholemia in both premature and full-term infants.  68:775-782. 1981

Deficiency of the autologous mixed lymphocyte reaction in patients with primary biliary cirrhosis.  66:1305-1310. 1980

Role of the renal sympathetic nerves in the development and maintenance of hypertension in the spontaneously hypertensive rat.  66:971-978. 1980

Effects of anion-transport inhibitors on NaCl reabsorption in the rat superficial proximal convoluted tubule.  64:570-579. 1979

Mechanism of postarrhythmic renal vasoconstriction in the anesthetized dog.  64:17-31. 1979

Recognition of hapten-modified cells in vitro by human T lymphocytes.  64:967-976. 1979

Selective induction of an immune response in human external secretions by ingestion of bacterial antigen..  61:731-737. 1978

A comparative analysis of the C1 binding ability of fragments derived from complement fixing and non complement fixing IgM proteins.  58:16-21. 1976

Effect of transfer factor on lymphocyte function in anergic patients..  51:2948-2958. 1972

FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2