Disease Models & Mechanisms


Publication Venue For

  • ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans.  12. 2019
  • Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers.  10:1353-1369. 2017
  • A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice.  10:837-845. 2017
  • Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology.  9:1169-1179. 2016
  • Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I.  9:759-767. 2016
  • Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs.  8:363-371. 2015
  • Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome.  8:941-955. 2015
  • TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS.  7:233-243. 2014
  • Preclinical research in Rett syndrome: Setting the foundation for translational success.  5:733-745. 2012
  • Understanding the genetic and molecular pathogenesis of Friedreich's ataxia through animal and cellular models.  5:165-176. 2012
  • Chemical enhancement of torsinA function in cell and animal models of torsion dystonia.  3:386-396. 2010
  • Target validation: The Parkinson disease perspective.  3:259-262. 2010
  • Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.  3:194-208. 2010
  • Traversing a wormhole to combat Parkinson's disease.  1:32-36. 2008