Positions

Overview

  • As a clinician-scientist John Owen has focused on collaborative research with many of my colleagues focusing on study design, data analysis and interpretation. Personal research interests include prematurity prevention and obstetric ultrasound. As former fellowship director, Dr. Owen also enjoys teaching our residents and MFM Fellows, especially in obstetric ultrasound.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 A contemporary amniotic fluid volume chart for the United States: The NICHD Fetal Growth Studies–Singletons 2019
    2019 Associations between estimated foetal weight discordance and clinical characteristics within dichorionic twins: The NICHD Fetal Growth Studies 2019
    2019 Estimating Gestational Age from Ultrasound: External Validation of the NICHD Formula with Comparison to the Hadlock Regression 2019
    2018 Estimating gestational age at birth from fundal height and additional anthropometrics: a prospective cohort study 2018
    2018 Fetal growth velocity: the NICHD fetal growth studies 2018
    2018 Maternal body mass index and oxytocin exposure in nulliparous women: is there an interaction associated with maternal and neonatal morbidities? 2018
    2018 Estimating gestational age with sonography: Regression-derived formula versus the fetal biometric average 2018
    2018 The Utility of Repeat Midtrimester Anatomy Ultrasound for Anomaly Detection 2018
    2018 Cohort profile: NICHD fetal growth studies- Singletons and twins 2018
    2018 Association of maternal obesity with longitudinal ultrasonographic measures of fetal growth: Findings from the nichd fetal growth studies-singletons 2018
    2017 Estimating Gestational Age from Ultrasound Fetal Biometrics 2017
    2017 Maternal Depressive Symptoms, Perceived Stress, and Fetal Growth 2017
    2017 Maternal stress and neonatal anthropometry: the NICHD Fetal Growth Studies 2017
    2017 Outcomes with cerclage alone compared with cerclage plus 17α-hydroxyprogesterone caproate 2017
    2016 Dichorionic twin trajectories: the NICHD Fetal Growth Studies 2016
    2016 The Performance of First-Trimester Anatomy Scan: A Decision Analysis 2016
    2016 Can the optimal cervical length for placing ultrasound-indicated cerclage be identified? 2016
    2016 Revisiting the cost-effectiveness of universal cervical length screening: Importance of progesterone efficacy 2016
    2016 Relationship between interpregnancy interval and cervical length in high-risk women 2016
    2016 Predictive Value of Initial Cervical Length for Subsequent Cervical Length Shortening in Women with a Prior Preterm Birth 2016
    2016 Cerclage: Shirodkar, McDonald, and modifications 2016
    2016 Vaginal cerclage: Preoperative, intraoperative, and postoperative management 2016
    2015 Racial/ethnic standards for fetal growth: The NICHD Fetal Growth Studies 2015
    2015 Ultrasonographic Fetal Weight Estimation: Should Macrosomia-Specific Formulas Be Utilized? 2015
    2015 Assessing white's classification of pregestational diabetes in a contemporary diabetic population 2015
    2015 Is low-dose aspirin therapy to prevent preeclampsia more efficacious in non-obese women or when initiated early in pregnancy? 2015
    2015 Nulliparous women in the second stage of labor 2015
    2015 Precocious cervical ripening as a screening target to predict spontaneous preterm delivery among asymptomatic singleton pregnancies: A systematic review 2015
    2014 The utility of ultrasound surveillance of fluid and growth in obese women 2014
    2014 Minimising perinatal mortality in twins: planned birth at 38 weeks of gestation for dichorionic and 36 weeks of gestation for monochorionic twins. 2014
    2014 Higher-Dose Oxytocin to Prevent Obstetric Hemorrhage at Vaginal Delivery-Does Duration of Infusion Matter? 2014
    2014 Minimising perinatal mortality in twins: Planned birth at 38 weeks of gestation for dichorionic and 36 weeks of gestation for monochorionic twins 2014
    2014 Mycoplasma, bacterial vaginosis-associated bacteria BVAB3, race, and risk of preterm birth in a high-risk cohort 2014
    2014 Risk factors for wound disruption following cesarean delivery 2014
    2014 Selected vaginal bacteria and risk of preterm birth: An ecological perspective 2014
    2013 Transvaginal cervical cerclage: Evidence for perioperative management strategies 2013
    2013 Oronasopharyngeal suction versus wiping of the mouth and nose at birth: A randomised equivalency trial 2013
    2013 Vaginal progesterone, cerclage or cervical pessary for preventing preterm birth in asymptomatic singleton pregnant women with a history of preterm birth and a sonographic short cervix: Editorial comment 2013
    2013 Vaginal progesterone, cerclage or cervical pessary for preventing preterm birth in asymptomatic singleton pregnant women with a history of preterm birth and a sonographic short cervix 2013
    2013 The association of maternal obesity with fetal pH and base deficit at cesarean delivery. 2013
    2012 Association between body mass index and pregnancy outcome in a randomized trial of cerclage for short cervix 2012
    2012 Cerclage for the prevention of preterm birth in high risk women receiving intramuscular 17-α-hydroxyprogesterone caproate 2012
    2012 Suture type and ultrasound-indicated cerclage efficacy 2012
    2012 Protocols for high-risk pregnancies 2012
    2012 What factors affect intrapartum maternal temperature? a prospective cohort study: Maternal intrapartum temperature 2012
    2012 Neonatal outcomes after implementation of guidelines limiting elective delivery before 39 weeks of gestation 2012
    2012 Cervical Cerclage for the Prevention of Preterm Birth 2012
    2011 Use of ethnic-specific medians for Hispanic patients reduces ethnic disparities in multiple marker screening 2011
    2011 Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: A meta-analysis 2011
    2011 Does midtrimester Nugent score or high vaginal pH predict gestational age at delivery in women at risk for recurrent preterm birth? 2011
    2011 High-dose oxytocin is not associated with maternal temperature elevation: A retrospective cohort study of mid-trimester pregnancy with intrauterine fetal demise 2011
    2011 Midtrimester bacterial vaginosis and cervical length in women at risk for preterm birth 2011
    2010 Middle cerebral artery median peak systolic velocity validation: Effect of measurement technique 2010
    2010 17-alpha-hydroxyprogesterone caproate for the prevention of preterm birth in women with prior preterm birth and a short cervical length 2010
    2010 Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length 2010
    2010 17-alpha-hydroxyprogesterone caproate for the prevention of preterm birth in women with prior preterm birth and a short cervical length 2010
    2010 Cervical funneling: Effect on gestational length and ultrasound-indicated cerclage in high-risk women 2010
    2010 Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women? 2010
    2010 Gestational age at previous preterm birth does not affect cerclage efficacy 2010
    2009 Racial disparities in perinatal outcomes and pregnancy spacing among women delaying initiation of childbearing 2009
    2009 Prevention of Preterm Birth Based on a Short Cervix: Cerclage 2009
    2009 Pregnancy spacing among women delaying initiation of childbearing 2009
    2009 Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length 2009
    2009 Racial disparities in perinatal outcomes and pregnancy spacing among women delaying initiation of childbearing 2009
    2009 Timing of mid-trimester cervical length shortening in high-risk women 2009
    2008 Interpregnancy interval and subsequent perinatal outcomes among women delaying initiation of childbearing 2008
    2008 Decreasing incidence of postcesarean endometritis with extended-spectrum antibiotic prophylaxis 2008
    2008 Impact of extended-spectrum antibiotic prophylaxis on incidence of postcesarean surgical wound infection 2008
    2007 Natural history of cervical funneling in women at high risk for spontaneous preterm birth 2007
    2006 Effect of coitus on recurrent preterm birth 2006
    2005 Do factors that are important during obstetrics and gynecology residency program selection differ by applicant gender? 2005
    2005 High-dose vaginal misoprostol versus concentrated oxytocin plus low-dose vaginal misoprostol for midtrimester labor induction: A randomized trial 2005
    2004 Obstetrics and gynecology residents' attitudes toward maternal-fetal medicine fellowship training 2004
    2004 Can shortened midtrimester cervical length predict very early spontaneous preterm birth? 2004
    2004 Number and gestational age of prior preterm births does not modify the predictive value of a short cervix 2004
    2004 Vaginal misoprostol versus concentrated oxytocin and vaginal PGE 2 for second-trimester labor induction 2004
    2004 Erratum: The association of maternal weight with cesarean risk, labor duration, and cervical dilation rate during labor induction (Obstetrics and Gynecology (March 2004) 103 (452-456) DOI: 10.1097/01.AOG.0000125151.53356.03) 2004
    2004 Fetal open spina bifida: A natural history of disease progression in utero 2004
    2004 Second-trimester cervical sonography: Features other than cervical length to predict spontaneous preterm birth 2004
    2004 The association of maternal weight with cesarean risk, labor duration, and cervical dilation rate during labor induction 2004
    2004 An outcomes analysis of five prenatal screening strategies for trisomy 21 in women younger than 35 years 2004
    2004 The Influence of Quality-of-Life, Academic, and Workplace Factors on Residency Program Selection 2004
    2003 Vaginal sonography and cervical incompetence 2003
    2003 Evaluation of the cervix by ultrasound for the prediction of preterm birth 2003
    2003 What we have learned about cervical ultrasound 2003
    2002 A randomized trial of intrapartum analgesia in women with severe preeclampsia 2002
    2002 A higher dose of oxytocin was more effective than a standard dose, when infused over 30 min, in preventing uterine atony after cesarean delivery 2002
    2001 Active phase labor arrest: Revisiting the 2-hour minimum 2001
    2001 Comparison of two oxytocin regimens to prevent uterine atony at cesarean delivery: A randomized controlled trial 2001
    2001 Mid-trimester endovaginal sonography in women at high risk for spontaneous preterm birth 2001
    2001 Can prenatal ultrasound findings predict ambulatory status in fetuses with open spina bifida? 2001
    2001 Laminaria versus extra-amniotic saline solution infusion for cervical ripening in second-trimester labor inductions 2001
    2000 Fronto-Ocular syndrome: Newly recognized trigonocephaly syndrome 2000
    2000 Sonography, suspected macrosomia, and prophylactic cesarean: A limited partnership 2000
    2000 Role of amniotic fluid homocysteine level and of fetal 5,10- methylenetetrahydrafolate reductase genotype in the etiology of neural tube defects 2000
    2000 Cardiovascular effects of intravaginal misoprostol in the mid trimester of pregnancy 2000
    2000 Criteria for failed labor induction: Prospective evaluation of a standardized protocol 2000
    2000 Extra-amniotic saline, laminaria, or prostaglandin E2 gel for labor induction with unfavorable cervix: A randomized controlled trial 2000
    2000 Midtrimester cervical ripening and labor induction 2000
    2000 Ultrasound findings and multiple marker screening in trisomy 18 2000
    1999 Relationship of gestational age and cervical dilation to the timing of delivery 1999
    1999 Vaginal misoprostol vs. concentrated oxytocin plus low-dose prostaglandin E2 for second trimester pregnancy termination 1999
    1999 Active-phase labor arrest: Oxytocin augmentation for at least 4 hours 1999
    1999 Indicated versus spontaneous preterm delivery: An evaluation of neonatal morbidity among infants weighing ≤1000 grams at birth 1999
    1999 Prophylactic cesarean delivery for fetal macrosomia diagnosed by means of ultrasonography - A Faustian bargain? 1999
    1999 Prospective evaluation of free β-subunit of human chorionic gonadotropin and dimeric inhibin A for aneuploidy detection 1999
    1999 The association of interleukin 6 with clinical and laboratory parameters of acute pelvic inflammatory disease 1999
    1999 Transperineal versus endovaginal ultrasonographic examination of the cervix in the midtrimester: A blinded comparison 1999
    1998 Decision analysis 1998
    1998 Prophylactic cesarean for prenatally diagnosed malformations 1998
    1998 Pregnancy outcomes following sonographic nonvisualization of the fetal stomach 1998
    1998 Intraoperative hypothermia and post-cesarean wound infection 1998
    1998 Does a high carbohydrate preparatory diet affect the 3-hour oral glucose tolerance test in pregnancy? 1998
    1998 A randomized trial of misoprostol and extra-amniotic saline infusion for cervical ripening and labor induction 1998
    1998 Maternal serum α-fetoprotein and dimeric inhibin A detect aneuploidies other than Down syndrome 1998
    1998 Routine maternal platelet count: An assessment of a technologically driven screening practice 1998
    1997 Alphafetoprotein (afp), free beta human chorionic gonadotrophin (fβhcg), and dimeric inhibin a (ih-a) produce the best results in a three-analyte multiple marker screening test for fetal down syndrome 1997
    1997 Amniotic fluid pulmonary maturity studies may be unnecessary in fetuses with meningomyelocele and hydrocephalus 1997
    1997 An assessment of fetal loss in twin pregnancy after midtrimester amniocentesis 1997
    1997 Free beta hcg subunit versus intact hcg in the multiple marker screening test for fetal down syndrome 1997
    1997 I pregnancy outcomes following sonographic nonvisuajjzation of the fetal stomach 1997
    1997 Induction in women with an unfavorable cervix: a randomized trial of extra-amniotic saline induction (easi) versus misoprostol 1997
    1997 Laminaria, extraamniotic saline induction (easi) or prepidil™ for cervical ripening prior to labor induction 1997
    1997 Management options in women with preterm uterine contractions: a randomized clinical trial 1997
    1997 Misoprostol versus concentrated oxytocin plus low-dose pge2 for mid-trimester pregnancy termination: a trial stopped 1997
    1997 Randomized trial of single dose versus multiple dose cefotetan for the postpartum treatment of intrapartum chorioamnionitis 1997
    1997 Significance of a false positive trjsomy 18 (t18) multiple marker screening test (mmst) 1997
    1997 Significance of a false-positive trisomy 18 multiple-marker screening test 1997
    1997 Sonographic measurements and ratios in fetuses with trisomy 18 1997
    1997 The effect of inaccurate gestational ace estimation on the multiple marker screening test (mmst) for fetal down syndrome (ds) 1997
    1997 Free β-hCG subunit versus intact hCG in Down syndrome screening 1997
    1997 Second-trimester maternal serum CA-125 versus estriol in the multiple-marker screening test for Down syndrome. 1997
    1997 Elevated second-trimester dimeric inhibin A levels identify Down syndrome pregnancies 1997
    1997 Management options in women with preterm uterine contractions: A randomized clinical trial 1997
    1997 Maternal serum human chorionic gonadotropin level at 15 weeks 1997
    1997 Maternal serum human chorionic gonadotropin level at 15 weeks. 1997
    1997 One- versus two-layer closure of a low transverse cesarean: The next pregnancy 1997
    1997 Randomized trial of single-dose versus multiple-dose cefotetan for the postpartum treatment of intrapartum chorioamnionitis 1997
    1997 Second-trimester maternal serum ca-125 versus estriol in the multiple-marker screening test for down syndrome 1997
    1997 α-fetoprotein, free β-human chorionic gonadotropin, and dimeric inhibin A produce the best results in a three-analyte, multiple-marker screening test for fetal Down syndrome 1997
    1996 Preterm delivery after indomethacin: A risk factor for neonatal complications? 1996
    1996 The effectiveness and costs of elective cesarean delivery for fetal macrosomia diagnosed by ultrasound 1996
    1996 On the use of surrogate end points for the calculation of the false- positive rate of antenatal testing [10] 1996
    1996 Complications of midtrimester pregnancy termination: The effect of prior cesarean delivery 1996
    1996 Concentrated oxytocin plus low-dose prostaglandin E2 compared with prostaglandin E2 vaginal suppositories for second-trimester pregnancy termination 1996
    1996 Dynamics of the fetal adrenal, cholesterol, and apolipoprotein B responses to antenatal betamethasone therapy 1996
    1996 Effect of parity correction on Down syndrome detection by the multiple- marker screening test 1996
    1996 Pregnancy outcome following genetic amniocentesis at 11-14 versus 16-19 weeks' gestation 1996
    1996 Prognostic significance of unexplained elevated amniotic fluid alpha-fetoprotein 1996
    1996 Second-trimester cystic hygroma: Prognosis of septated and nonseptated lesions 1996
    1996 The effect of manual removal of the placenta on post-cesarean endometritis 1996
    1996 The significance of non-visualization of the fetal bladder during an ultrasound examination to evaluate second-trimester oligohydramnios 1996
    1995 Comparion of multiple-marker screening with amniocentesis for the detection of fetal aneuploidy in women ≥35 years old 1995
    1995 Determinants of the optimal time in gestation to initiate antenatal fetal testing: A decision-analytic approach 1995
    1995 Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? 1995
    1995 Gestational diabetes survey 1995
    1995 Screening and treatment of asymptomatic bacteriuria of pregnancy to prevent pyelonephritis: A cost-effectiveness and cost-benefit analysis 1995
    1995 Subcutaneous tissue approximation in relation to wound disruption after cesarean delivery in obese women 1995
    1995 The influence of maternal weight on human chorionic gonadotropin in the multiple-marker screening test for fetal Down syndrome 1995
    1995 Will αfetoprotein analysis be useful in detecting fetal anomalies in the first trimester? 1995
    1995 Zidovudine for the prevention of vertical HIV transmission: A decision analytic approach 1995
    1994 Active-phase labor arrest: A randomized trial of chorioamnion management 1994
    1994 Elevated second-trimester human chorionic gonadotropin levels in association with poor pregnancy outcome 1994
    1994 Fetal Echocardiography in Gravidas with Historic Risk Factors for Congenital Heart Disease 1994
    1994 Prediction of preterm birth in nulliparous patients 1994
    1994 The predictive value of umbilical artery Doppler studies for preeclampsia or fetal growth retardation in a preeclampsia prevention trial 1994
    1994 The utility of fetal biometry as an adjunct to the multiple-marker screening test for Down syndrome 1994
    1994 Wound complications after cesarean sections 1994
    1993 Crosa-sectional study examining the relationship between fetal urine production and the amniotic fluid index at 38-43 weeks of gestation 1993
    1993 Cross-sectional study examining the relationship between fetal urine production and the amniotic fluid index at 38–43 weeks of gestation 1993
    1993 Randomized trial of prophylactic antibiotic therapy after preterm amnion rupture 1993
    1993 The effect of low-dose aspirin on fetal urine output and amniotic fluid volume 1993
    1993 The effect of low-dose aspirin on umbilical artery Doppler measurements 1993
    1993 Trial of labor after a one- or two-layer closure of a low transverse uterine incision 1993
    1992 Hemorrhagic endovasculitis of the placenta and fetomaternal hemorrhage: A relationship? 1992
    1992 Midtrimester pregnancy termination: A randomized trial of prostaglandin E2 versus concentrated oxytocin 1992
    1992 Oxytocin for the induction or augmentation of labor 1992
    1992 Transverse uterine incision closure: One versus two layers 1992
    1991 Mid-second-trimester labor induction: Concentrated oxytocin compared with prostaglandin E2 vaginal suppositories 1991
    1991 Neonatal complications at term as related to the degree of umbilical artery acidemia 1991
    1991 Oligohydramnios: Antepartum fetal urine production and intrapartum fetal distress 1991
    1991 Reply 1991
    1991 Was there really a difference with amnioinfusion? (Reply) 1991
    1990 A prospective randomized study of saline solution amnioinfusion 1990
    1990 Evaluation of a risk scoring system as a predictor of preterm birth in an indigent population 1990
    1990 Is indicated or spontaneous preterm delivery more advantageous for the fetus? 1990
    1990 Magnesium tocolysis: Serum levels versus success 1990
    1989 A comparison of perinatal outcome in patients undergoing contraction stress testing performed by nipple stimulation versus spontaneously occurring contractions 1989
    1989 Comparison of predelivery versus postdelivery Kleihauer-Betke stains in cases of fetal death 1989
    1989 Polyarteritis nodosa in pregnancy: A case report and brief literature review 1989
    1988 Apolipoprotein A-1 in umbilical cord blood of newborn infants: Relation to gestational age and high-density lipoprotein cholesterol 1988
    1988 Fetal death after successful conversion of fetal supraventricular tachycardia with digoxin and verapamil 1988
    1987 Transporting mothers with fetuses in utero to a level III perinatal center. Report of a clinical experience, 1978-1982. 1987

    Chapter

    Year Title Altmetric
    2015 Cervical Insufficiency.  288-297. 2015
    2012 Cervical Insufficiency.  271-279. 2012
    2010 Cervical Insufficiency.  373-382. 2010
    2008 The Incompetent Cervix.  263-270. 2008

    Research Overview

  • -Fetal ultrasound
    -Fetal therapy
    -Labor management
  • Education And Training

  • UAB Hospital, Internship 1983
  • UAB Hospital, Residency 1986
  • UAB Hospital, Postdoctoral Fellowship 1988
  • Full Name

  • John Owen