Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Mycobacterium tuberculosis H2S functions as a sink to modulate central metabolism, bioenergetics, and drug susceptibility 2021
2021 µCT Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in 3D Granuloma Morphology..  American Journal of Respiratory and Critical Care Medicine.  2021
2020 Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis.  Nature Communications.  11. 2020
2020 Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.  Nature Communications.  11. 2020
2020 The Role of Host-Generated H2S in Microbial Pathogenesis: New Perspectives on Tuberculosis.  Frontiers in Cellular and Infection Microbiology.  10. 2020
2019 Erratum: Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis (Cell Reports (2018) 25(7) (1938–1952.e5), (S2211124718316772), (10.1016/j.celrep.2018.10.073)).  Cell Reports.  28:3286. 2019
2018 Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.  Cell Reports.  25:1938-1952.e5. 2018
2018 Ferritin H deficiency in myeloid compartments dysregulates host energy metabolism and increases susceptibility to Mycobacterium tuberculosis infection.  Frontiers in Immunology.  9. 2018
2016 The emerging role of gasotransmitters in the pathogenesis of tuberculosis.  Nitric Oxide: Biology and Chemistry.  59:28-41. 2016
2016 Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis.  Cell Reports.  14:572-585. 2016
2014 Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy.  Viruses.  6:3293-3310. 2014
2013 An Adenovirus Vector Incorporating Carbohydrate Binding Domains Utilizes Glycans for Gene Transfer.  PLoS ONE.  8. 2013
2012 Iron sulfur cluster proteins and microbial regulation: Implications for understanding tuberculosis.  Current Opinion in Chemical Biology.  16:45-53. 2012
2010 An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations.  Virology.  407:196-205. 2010
2010 Transduction of brain dopamine neurons by adenoviral vectors is modulated by car expression: Rationale for tropism modified vectors in PD gene therapy.  PLoS ONE.  5:1-9. 2010
2010 Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains.  Journal of Virology.  84:10558-10568. 2010
2009 A strategy for adenovirus vector targeting with a secreted single chain antibody.  PLoS ONE.  4. 2009
2009 Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre 2009
2009 A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo.  Vaccine.  27:7116-7124. 2009
2008 Enhanced gene delivery to human primary endothelial cells using tropism-modified adenovirus vectors.  Open Gene Therapy Journal.  1:7-11. 2008
2008 Localization of the N-Terminus of Minor Coat Protein IIIa in the Adenovirus Capsid.  Journal of Molecular Biology.  383:923-934. 2008
2008 A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration.  Blood.  112:2353-2359. 2008
2008 Characterization of infectivity of knob-modified adenoviral vectors in glioma..  Cancer Biology and Therapy.  7:786-793. 2008
2008 Characterization of infectivity of knob-modified adenoviral vectors in glioma.  Cancer Biology and Therapy.  7:788-795. 2008
2007 Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models.  Neuro-Oncology.  9:280-290. 2007
2007 A mosaic fiber adenovirus serotype 5 vector containing reovirus σ1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.  Clinical Cancer Research.  13:2777-2783. 2007
2007 Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: Implications for clinical efficacy.  Journal of Virology.  81:3272-3284. 2007
2007 Novel recombinant adenoviral vector that targets the interleukin-13 receptor α2 chain permits effective gene transfer to malignant glioma.  Human Gene Therapy.  18:118-129. 2007
2006 Transductional targeting of adenovirus vectors for gene therapy.  Cancer Gene Therapy.  13:830-844. 2006
2006 An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice.  Virology.  350:103-115. 2006
2006 Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells 2006
2006 An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery 2006
2005 A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy 2005
2005 In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model.  Journal of Gene Medicine.  7:1517-1525. 2005
2005 Reovirus σ1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway.  Biochemical and Biophysical Research Communications.  335:205-214. 2005
2005 Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors 2005
2005 Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy 2005
2004 An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism.  Virology.  324:103-116. 2004
2004 Transductional and transcriptional targeting of adenovirus for clinical applications 2004
2003 A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism.  Virology.  309:282-293. 2003
2002 A model system for the design of armed replicating adenoviruses using p53 as a candidate transgene.  Molecular Cancer Therapeutics.  1:321-328. 2002
2001 Differential NF-κB regulation of bcl-x gene expression in hippocampus and basal forebrain in response to hypoxia.  Journal of Neuroscience Research.  64:223-234. 2001
2001 Transcriptional regulation of the BCL-X gene by NF-κB is an element of hypoxic responses in the rat brain.  Neurochemical Research.  26:647-659. 2001
2000 Identification and characterization of nuclear factor κB binding sites in the murine bcl-x promoter.  Journal of Neurochemistry.  75:1377-1389. 2000
2000 NGF-mediated alteration of NF-κB binding activity after partial immunolesions to rat cholinergic basal forebrain neurons.  International Journal of Developmental Neuroscience.  18:455-468. 2000
2000 One Path to Cell Death in the Nervous System.  Neurochemical Research.  25:1373-1383. 2000
1994 Mutagenesis of the cyclic AMP receptor protein of Escherichia coli: Targeting positions 83, 127 and 128 the cyclic nucleotide binding pocket.  Nucleic Acids Research.  22:2894-2901. 1994

Chapter

Year Title Altmetric
2021 Chapter 4: Modified Adenoviruses for Gene Therapy.  69-78. 2021

Teaching Activities

Education And Training

  • Doctor of Philosophy in Cell / Cellular and Molecular Biology, The University of Texas Medical Branch 2000
  • Bachelor of Science or Mathematics in Chemistry, Texas Tech University 1994
  • University of Alabama at Birmingham Division of Human Gene Therapy, Postdoctoral Fellowship 2003

    • Full Name

  • Joel Glasgow