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Joel Glasgow
Assistant Professor
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E-mail
jng@uab.edu
Phone
205-996-4805
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Joel Glasgow
Assistant Professor
Positions
Scientist (C)
,
Neurodegeneration and Experimental Therapeutics (CNET)
,
Neurology
2007 -
Scientist (C)
,
Comprehensive Neuroscience Center
,
General Clinical Research Center
2009 -
Scientist (C)
,
Center for Cardiovascular Biology (Retired Org)
,
Medicine - Cardiovascular Disease
2010 -
Assistant Professor (P)
,
Microbiology
,
Academic Joint Departments
2011 -
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
Altmetric
2020
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis
.
Nature Communications
. 11.
2020
2020
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis
.
Nature Communications
. 11.
2020
2020
The Role of Host-Generated H
2
S in Microbial Pathogenesis: New Perspectives on Tuberculosis
.
Frontiers in Cellular and Infection Microbiology
. 10.
2020
2019
Erratum: Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis (Cell Reports (2018) 25(7) (1938–1952.e5), (S2211124718316772), (10.1016/j.celrep.2018.10.073))
.
Cell Reports
. 28:3286.
2019
2018
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis
.
Cell Reports
. 25:1938-1952.e5.
2018
2018
Ferritin H deficiency in myeloid compartments dysregulates host energy metabolism and increases susceptibility to Mycobacterium tuberculosis infection
.
Frontiers in Immunology
. 9.
2018
2016
The emerging role of gasotransmitters in the pathogenesis of tuberculosis
.
Nitric Oxide: Biology and Chemistry
. 59:28-41.
2016
2016
Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis
.
Cell Reports
. 14:572-585.
2016
2014
Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy
.
Viruses
. 6:3293-3310.
2014
2013
An Adenovirus Vector Incorporating Carbohydrate Binding Domains Utilizes Glycans for Gene Transfer
.
PLoS ONE
. 8.
2013
2012
Iron sulfur cluster proteins and microbial regulation: Implications for understanding tuberculosis
.
Current Opinion in Chemical Biology
. 16:45-53.
2012
2010
An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations
.
Virology
. 407:196-205.
2010
2010
Transduction of brain dopamine neurons by adenoviral vectors is modulated by car expression: Rationale for tropism modified vectors in PD gene therapy
.
PLoS ONE
. 5:1-9.
2010
2010
Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains
.
Journal of Virology
. 84:10558-10568.
2010
2009
A strategy for adenovirus vector targeting with a secreted single chain antibody
.
PLoS ONE
. 4.
2009
2009
Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre
2009
2009
A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo
.
Vaccine
. 27:7116-7124.
2009
2008
Enhanced gene delivery to human primary endothelial cells using tropism-modified adenovirus vectors
.
Open Gene Therapy Journal
. 1:7-11.
2008
2008
Localization of the N-Terminus of Minor Coat Protein IIIa in the Adenovirus Capsid
.
Journal of Molecular Biology
. 383:923-934.
2008
2008
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration
.
Blood
. 112:2353-2359.
2008
2008
Characterization of infectivity of knob-modified adenoviral vectors in glioma.
.
Cancer Biology and Therapy
. 7:786-793.
2008
2008
Characterization of infectivity of knob-modified adenoviral vectors in glioma
.
Cancer Biology and Therapy
. 7:788-795.
2008
2007
Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models
.
Neuro-Oncology
. 9:280-290.
2007
2007
A mosaic fiber adenovirus serotype 5 vector containing reovirus σ1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway
.
Clinical Cancer Research
. 13:2777-2783.
2007
2007
Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: Implications for clinical efficacy
.
Journal of Virology
. 81:3272-3284.
2007
2007
Novel recombinant adenoviral vector that targets the interleukin-13 receptor α2 chain permits effective gene transfer to malignant glioma
.
Human Gene Therapy
. 18:118-129.
2007
2006
Transductional targeting of adenovirus vectors for gene therapy
.
Cancer Gene Therapy
. 13:830-844.
2006
2006
An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice
.
Virology
. 350:103-115.
2006
2006
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells
2006
2006
An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery
2006
2005
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy
2005
2005
In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model
.
Journal of Gene Medicine
. 7:1517-1525.
2005
2005
Reovirus σ1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway
.
Biochemical and Biophysical Research Communications
. 335:205-214.
2005
2005
Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors
2005
2005
Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy
2005
2004
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism
.
Virology
. 324:103-116.
2004
2004
Transductional and transcriptional targeting of adenovirus for clinical applications
2004
2003
A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism
.
Virology
. 309:282-293.
2003
2002
A model system for the design of armed replicating adenoviruses using p53 as a candidate transgene
.
Molecular Cancer Therapeutics
. 1:321-328.
2002
2001
Differential NF-κB regulation of bcl-x gene expression in hippocampus and basal forebrain in response to hypoxia
.
Journal of Neuroscience Research
. 64:223-234.
2001
2001
Transcriptional regulation of the BCL-X gene by NF-κB is an element of hypoxic responses in the rat brain
.
Neurochemical Research
. 26:647-659.
2001
2000
Identification and characterization of nuclear factor κB binding sites in the murine bcl-x promoter
.
Journal of Neurochemistry
. 75:1377-1389.
2000
2000
NGF-mediated alteration of NF-κB binding activity after partial immunolesions to rat cholinergic basal forebrain neurons
.
International Journal of Developmental Neuroscience
. 18:455-468.
2000
2000
One Path to Cell Death in the Nervous System
.
Neurochemical Research
. 25:1373-1383.
2000
1994
Mutagenesis of the cyclic AMP receptor protein of Escherichia coli: Targeting positions 83, 127 and 128 the cyclic nucleotide binding pocket
.
Nucleic Acids Research
. 22:2894-2901.
1994
Research
Principal Investigator On
Magnetothermally-Triggered Drug Release from Block Copolymer Micelles
awarded by
UNIVERSITY OF ALABAMA (TUSCALOOSA)
2010 - 2012
Investigator On
Interplay Between the Mtb Electron Transport Chain and Carbon Metabolism
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2018 - 2023
Carbon Monoxide and Mycobacterium Tuberculosis Persistance
awarded by
Burroughs Wellcome Fund
2008 - 2016
Role of WhiB3 in M. tuberculosis Virulence
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2010 - 2016
Background
Education And Training
Doctor of Philosophy in Cell / Cellular and Molecular Biology,
The University of Texas Medical Branch
2000
Bachelor of Science or Mathematics in Chemistry,
Texas Tech University
1994
University of Alabama at Birmingham Division of Human Gene Therapy, Postdoctoral Fellowship
2003
Contact
Full Name
Joel
Glasgow