Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Mitochondrial quality control in pulmonary fibrosisRedox Biology.  33. 2020
2020 A novel tree shrew model of pulmonary fibrosisLaboratory Investigation2020
2019 Increased flux through the mevalonate pathway mediates fibrotic repair without injuryJournal of Clinical Investigation.  129:4962-4978. 2019
2019 Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosisRedox Biology.  26. 2019
2019 NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosisJCI insight.  4. 2019
2019 Reply to Eapen et al.: Dysfunctional immunity and microbial adhesion molecules in smoking-induced pneumoniaAmerican Journal of Respiratory and Critical Care Medicine.  199:251-252. 2019
2018 Macrophage Rac2 is required to reduce the severity of cigarette smoke-induced pneumoniaAmerican Journal of Respiratory and Critical Care Medicine.  198:1288-1301. 2018
2017 Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarizationThe FASEB Journal.  31:3072-3083. 2017
2016 Assay to evaluate BAL Fluid regulation of Fibroblast α-SMA Expression.Bio-protocol.  6. 2016
2016 Determination of H2O2 Generation by pHPA Assay.Bio-protocol.  6. 2016
2016 Cu,Zn-superoxide dismutase-mediated redox regulation of Jumonji domain containing 3 modulates macrophage polarization and pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  55:58-71. 2016
2016 Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary FibrosisImmunity.  44:582-596. 2016
2016 SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As+3- and Cd+2-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARCPLoS ONE.  11. 2016
2015 Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structureThe FASEB Journal.  29:3527-3536. 2015
2015 Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosisFree Radical Biology and Medicine.  86:47-56. 2015
2014 Modulation of the mevalonate pathway by AKT regulates macrophage survival and development of pulmonary fibrosisJournal of Biological Chemistry.  289:36204-36219. 2014
2014 3 Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophagesJournal of Biological Chemistry.  289:33391-33403. 2014
2011 Comparison of expression patterns of keratin 6, 7, 16, 17, and 19 within multiple independent isolates of As +3- and Cd +2-induced bladder cancer: Keratin 6, 7, 16, 17, and 19 in bladder cancer 2011
2010 SPARC gene expression is repressed in human urothelial cells (UROtsa) exposed to or malignantly transformed by cadmium or arseniteToxicology Letters.  199:166-172. 2010
2010 Beclin-1 expression in normal bladder and in Cd2+ and As3+ exposed and transformed human urothelial cells (UROtsa)Toxicology Letters.  195:15-22. 2010

Education And Training

  • University of Iowa Medicine, Postdoctoral Research 2014
  • Doctor of Philosophy in Cell Biology and Anatomy, University of North Dakota 2012
  • Full Name

  • Jennifer Casey