Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Effect of the Bruder moist heat eye compress on contact lens discomfort in contact lens wearers: An open-label randomized clinical trialSan Diego Law Review.  42:625-632. 2019
2019 Characterization of the thickness of the tear film lipid layer using high resolution microscopyOcular Surface.  17:356-359. 2019
2019 Untargeted lipidomic analysis of human tears: A new approach for quantification of O-acyl-omega hydroxy fatty acidsOcular Surface.  17:347-355. 2019
2019 Impact of the 2011 International Workshop on Meibomian Gland Dysfunction on clinical trial attributes for meibomian gland dysfunctionOcular Surface2019
2018 An imaging system integrating optical coherence tomography and interferometry for in vivo measurement of the thickness and dynamics of the tear filmCancer Informatics.  17:164. 2018
2018 An imaging-based analysis of lipid deposits on contact lens surfacesSan Diego Law Review.  41:342-350. 2018
2018 Glycoprotein 340 in mucosal immunity and ocular surfaceOcular Surface.  16:282-288. 2018
2017 Advances in thickness measurements and dynamic visualization of the tear film using non-invasive optical approachesProgress in Retinal and Eye Research.  58:28-44. 2017
2016 Ocular Surface Membrane-Associated MucinsOcular Surface.  14:331-341. 2016
2016 Global trends in myopia management attitudes and strategies in clinical practiceSan Diego Law Review.  39:106-116. 2016
2016 Analysis of tear inflammatory mediators: A comparison between the microarray and luminex methodsMolecular Vision.  22:177-188. 2016
2016 Over the counter (OTC) artificial tear drops for dry eye syndromeClinical Spine Surgery.  2016. 2016
2016 Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal womenInvestigative Ophthalmology & Visual Science.  57:295-300. 2016
2015 Agreement between automated and traditional measures of tear film breakupOptometry and Vision Science.  92:e257-e263. 2015
2015 Association between meibomian gland testing and ocular surface sensitivityCurrent Womens Health Reports.  34:1187-1192. 2015
2015 Dry eye diseaseOptometry and Vision Science.  92:922-924. 2015
2015 Trends in US contact lens prescribing 2002 to 2014Optometry and Vision Science.  92:758-767. 2015
2014 Tear film interferometry and corneal surface roughnessInvestigative Ophthalmology & Visual Science.  55:2614-2618. 2014
2014 Compliance factors associated with contact lens-related dry eyeScience in China Series A: Mathematics.  40:17-22. 2014
2014 The neurobiology of the meibomian glandsOcular Surface.  12:167-177. 2014
2013 The TFOS International Workshop on Contact Lens Discomfort: Executive summaryInvestigative Ophthalmology & Visual Science.  54. 2013
2013 The TFOS International Workshop on Contact Lens Discomfort: IntroductionInvestigative Ophthalmology & Visual Science.  54. 2013
2013 The TFOS International Workshop on Contact Lens Discomfort: Report of the contact lens materials, design, and care subcommitteeInvestigative Ophthalmology & Visual Science.  54. 2013
2013 The TFOS International Workshop on Contact Lens Discomfort: Report of the definition and classification subcommitteeInvestigative Ophthalmology & Visual Science.  54. 2013
2013 Tear film images and breakup analyzed using fluorescent quenchingInvestigative Ophthalmology & Visual Science.  54:6003-6011. 2013
2013 Tear film breakup and structure studied by simultaneous video recording of fluorescence and tear film lipid layer imagesInvestigative Ophthalmology & Visual Science.  54:4900-4909. 2013
2013 Long-term contact lens wear of children and teensScience in China Series A: Mathematics.  39:283-289. 2013
2013 Interventions for acute internal hordeolumClinical Spine Surgery.  2013. 2013
2013 1. History, evolution, and evolving standards of contact lens careSan Diego Law Review.  36. 2013
2013 1. History, evolution, and evolving standards of contact lens care.San Diego Law Review.  36 Suppl 1:S4-S8. 2013
2013 3. Ocular surface health with contact lens wearSan Diego Law Review.  36. 2013
2013 3. Ocular surface health with contact lens wear.San Diego Law Review.  36 Suppl 1:S14-S21. 2013
2013 An international survey of daily disposable contact lens prescribingSuperconductor Science and Technology.  96:58-64. 2013
2013 Citation analysis of the dry eye literatureOcular Surface.  11:35-46. 2013
2013 Deposition on silicone hydrogel lensesScience in China Series A: Mathematics.  39:20-23. 2013
2012 The use of fluorescent quenching in studying the contribution of evaporation to tear thinningInvestigative Ophthalmology & Visual Science.  53:5426-5432. 2012
2012 A method of imaging lipids on silicone hydrogel contact lensesOptometry and Vision Science.  89. 2012
2012 A review of meibography.Optometry and Vision Science.  89. 2012
2012 Imaging and measurement in the eye: Now and aheadOptometry and Vision Science.  89:521-523. 2012
2012 Development of the 4-3-2-1 meibum expressibility scaleScience in China Series A: Mathematics.  38:86-92. 2012
2012 Relation between upper and lower lids' meibomian gland morphology, tear film, and dry eyeOptometry and Vision Science.  89. 2012
2012 Safety and efficacy of topical azithromycin ophthalmic solution 1.0% in the treatment of contact lens-related dry eyeScience in China Series A: Mathematics.  38:73-79. 2012
2012 Analysis of meibum and tear lipidsOcular Surface.  10:230-250. 2012
2012 Citation analysis of the contact lens fieldOptometry and Vision Science.  89:70-79. 2012
2012 Inter-examiner reliability in meibomian gland dysfunction assessment.Investigative Ophthalmology & Visual Science.  53:3120-3125. 2012
2011 Rasch analysis of the Ocular Surface Disease Index (OSDI)Investigative Ophthalmology & Visual Science.  52:8630-8635. 2011
2011 An international analysis of contact lens complianceSan Diego Law Review.  34:223-228. 2011
2011 Examination of human meibum collection and extraction techniquesOptometry and Vision Science.  88:525-533. 2011
2011 The international workshop on meibomian gland dysfunction: Report of the subcommittee on the epidemiology of, and associated risk factors for, MGDInvestigative Ophthalmology & Visual Science.  52:1994-2005. 2011
2011 Global trends in prescribing contact lenses for extended wearSan Diego Law Review.  34:32-35. 2011
2011 Soft toric contact lens prescribing in different countriesSan Diego Law Review.  34:36-38. 2011
2011 Tear film, contact lens, and patient factors associated with corneal stainingInvestigative Ophthalmology & Visual Science.  52:1127-1137. 2011
2011 High resolution microscopy of the lipid layer of the tear filmOcular Surface.  9:197-211. 2011
2010 Evidence for the major contribution of evaporation to tear film thinning between blinksInvestigative Ophthalmology & Visual Science.  51:6294-6297. 2010
2010 In vitro lipid deposition on hydrogel and silicone hydrogel contact lensesInvestigative Ophthalmology & Visual Science.  51:6334-6340. 2010
2010 Tear proteomics in keratoconusMolecular Vision.  16:1949-1957. 2010
2010 Evaluation of extractants and precipitants in tear film proteomic analysesOptometry and Vision Science.  87:854-860. 2010
2010 Daily disposable contact lens prescribing around the worldSan Diego Law Review.  33:225-227. 2010
2010 Twenty first century trends in silicone hydrogel contact lens fitting: An international perspectiveSan Diego Law Review.  33:196-198. 2010
2010 Enzymatic quantification of cholesterol and cholesterol esters from silicone hydrogel contact lensesInvestigative Ophthalmology & Visual Science.  51:2949-2954. 2010
2010 Gas permeable and soft contact lens wear in childrenOptometry and Vision Science.  87:414-420. 2010
2010 International rigid contact lens prescribingSan Diego Law Review.  33:141-143. 2010
2010 Application of a novel interferometric method to investigate the relation between lipid layer thickness and tear film thinningInvestigative Ophthalmology & Visual Science.  51:2418-2423. 2010
2010 Texture based prelens tear film segmentation in interferometry imagesMachine Vision and Applications.  21:253-259. 2010
2010 Contact lens material characteristics associated with hydrogel lens dehydrationOphthalmic and Physiological Optics.  30:160-166. 2010
2010 Demographics of international contact lens prescribingSan Diego Law Review.  33:27-29. 2010
2010 Interventions for acute internal hordeolum.Clinical Spine Surgery.  9. 2010
2010 Prevention of UV-induced damage to the anterior segment using class I UV-absorbing hydrogel contact lensesInvestigative Ophthalmology & Visual Science.  51:172-178. 2010
2009 The contribution of lipid layer movement to tear film thinning and breakupInvestigative Ophthalmology & Visual Science.  50:2747-2756. 2009
2009 Interventions for acute internal hordeolumClinical Spine Surgery2009
2009 Impact of a rinse step on protein removal from silicone hydrogel contact lensesOptometry and Vision Science.  86:943-947. 2009
2009 Mass spectrometry-based proteomic analyses in contact lens-related dry eye.Current Womens Health Reports.  28:1109-1117. 2009
2009 Proteins identified from care solution extractions of silicone hydrogelsOptometry and Vision Science.  86:E123-E131. 2009
2008 Contributions of evaporation and other mechanisms to tear film thinning and break-upOptometry and Vision Science.  85:623-630. 2008
2008 Dry eye and designer ophthalmicsOptometry and Vision Science.  85:643-652. 2008
2008 Treatment, material, care, and patient-related factors in contact lens-related dry eyeOptometry and Vision Science.  85:764-772. 2008
2008 Hydrogel contact lens binding induced by contact lens rewetting dropsOptometry and Vision Science.  85:236-240. 2008
2008 Investigation of the human tear film proteome using multiple proteomic approachesMolecular Vision.  14:456-470. 2008
2008 Mass spectrometry-based proteomic analyses of contact lens depositionMolecular Vision.  14:291-297. 2008
2008 Mucins in Contact Lens Wear and Dry Eye ConditionsOptometry and Vision Science.  85:E631-E642. 2008
2008 The impact of punctal occlusion on soft contact lens wearing comfort and the tear film.Science in China Series A: Mathematics.  34:261-265. 2008
2007 Frequency of and factors associated with contact lens dissatisfaction and discontinuationCurrent Womens Health Reports.  26:168-174. 2007
2007 Identification of fatty acids and fatty acid amides in human meibomian gland secretionsInvestigative Ophthalmology & Visual Science.  48:34-39. 2007
2007 The contact lens and tear film laboratory, The Ohio State University College of OptometryOcular Surface.  5:259-261. 2007
2006 Relation between mood and self-reported dry eye in contact lens wearersCurrent Womens Health Reports.  25:937-942. 2006
2006 Deposition rates and lens care influence on galyfilcon a silicone hydrogel lensesOptometry and Vision Science.  83:751-757. 2006
2006 Reliability of grading lissamine green conjunctival stainingCurrent Womens Health Reports.  25:695-700. 2006
2006 Reliability of grading lissamine green conjunctival stainingCurrent Womens Health Reports.  25:695-700. 2006
2006 Tear film, contact lens, and patient-related factors associated with contact lens-related dry eyeInvestigative Ophthalmology & Visual Science.  47:1319-1328. 2006
2006 Longitudinal changes in visual acuity in keratoconusInvestigative Ophthalmology & Visual Science.  47:489-500. 2006
2006 Interferometric imaging of the full thickness of the precorneal tear filmJournal of the Optical Society of America A.  23:2097-2104. 2006
2005 Sensitivity of the National Eye Institute Refractive Error Quality of Life instrument to refractive surgery outcomesJournal of Cataract and Refractive Surgery.  31:2313-2318. 2005
2005 The reliability of the Lanthony Desaturated D-15 testOptometry and Vision Science.  82:1054-1059. 2005
2005 Thinning rate of the precorneal and prelens tear filmsInvestigative Ophthalmology & Visual Science.  46:2353-2361. 2005
2005 The impact of contact lens care solutions on the thickness of the tear film and contact lensCurrent Womens Health Reports.  24:825-832. 2005
2005 Self-reported dry eye disease across refractive modalitiesInvestigative Ophthalmology & Visual Science.  46:1911-1914. 2005
2005 An assessment of grading scales for meibography imagesCurrent Womens Health Reports.  24:382-388. 2005
2005 Assessment of meibomian lipids in postmenopausal women using electrospray ionization mass spectrometryInvestigative Ophthalmology & Visual Science.  46. 2005
2005 Human tear film breakup studied by a new imaging interferometer: Preliminary observationsInvestigative Ophthalmology & Visual Science.  46. 2005
2005 Identification and analysis of polar and non-polar lipids from meibomian gland secretions using electrospray ionization mass spectrometryInvestigative Ophthalmology & Visual Science.  46. 2005
2005 The relation between self-reported mood and self-reported dry eye in contact lens wearersInvestigative Ophthalmology & Visual Science.  46. 2005
2004 The lack of association between signs and symptoms in patients with dry eye diseaseCurrent Womens Health Reports.  23:762-770. 2004
2004 An assessment of self-reported disease classification in epidemiological studies of dry eyeInvestigative Ophthalmology & Visual Science.  45:3453-3457. 2004
2004 The impact of hydrogel lens settling on the thickness of the tears and contact lensInvestigative Ophthalmology & Visual Science.  45:2549-2554. 2004
2004 Characteristics of corneal ectasia after LASIK for myopiaCurrent Womens Health Reports.  23:447-457. 2004
2004 The relation between disease asymmetry and severity in keratoconusNature Reviews Neurology.  88:788-791. 2004
2004 The Reliability and Validity of McMonnies Dry Eye IndexCurrent Womens Health Reports.  23:365-371. 2004
2004 Assessment of the reliability of self-reported dry eye in contact lens wearers: The contact lens dry eye questionnaire (CLDEQ) short-formInvestigative Ophthalmology & Visual Science.  45:U142-U142. 2004
2003 The assessment of automated measures of hydrogel contact lens refractive indexOphthalmic and Physiological Optics.  23:517-525. 2003
2003 The relation between tear film tests in patients with dry eye diseaseOphthalmic and Physiological Optics.  23:553-560. 2003
2003 Reliability and validity of refractive error-specific quality-of-life instrumentsHuman Pathology.  121:1289-1296. 2003
2003 The effect of eye closure on the post-lens tear film thickness during silicone hydrogel contact lens wearCurrent Womens Health Reports.  22:539-544. 2003
2003 The reliability and validity of hand-held refractometry water content measures of hydrogel lensesOptometry and Vision Science.  80:447-453. 2003
2003 Characteristics of corneal ectasia after myopic LASIKInvestigative Ophthalmology & Visual Science.  44:U20-U20. 2003
2003 Reliability of corneal thickness and endothelial cell density measuresJournal of Refractive Surgery.  19:344-352. 2003
2003 The relation between disease asymmetry and severity in keratoconusInvestigative Ophthalmology & Visual Science.  44:U312-U312. 2003
2003 Thickness of the pre- and post-contact lens tear film measured in vivo by interferometryInvestigative Ophthalmology & Visual Science.  44:68-77. 2003
2002 Refractive status and vision profile survey in a contact lens trial [2] (multiple letters)Ophthalmology: Journal of The American Academy of Ophthalmology.  109:2188-2190. 2002
2002 Refractive status and vision profile survey in contact lens trial: Author replyOphthalmology: Journal of The American Academy of Ophthalmology.  109:2190-2192. 2002
2002 The thickness of the post-lens tear film measured by interferometryTransplantation.  506 B:929-933. 2002
2002 Between-eye asymmetry in keratoconusCurrent Womens Health Reports.  21:671-679. 2002
2002 The performance of the contact lens dry eye questionnaire as a screening survey for contact lens-related dry eyeCurrent Womens Health Reports.  21:469-475. 2002
2002 In vivo measurement of the thickness of human corneal endothelium and Descemet's membrane using interferometryInvestigative Ophthalmology & Visual Science.  43:U27-U27. 2002
2002 Is there an association between signs and symptoms in patients with dry eye?Investigative Ophthalmology & Visual Science.  43:U1117-U1117. 2002
2002 The evaluation of cornea-to-contact lens base curve relationships in keratoconus through fluorescein pattern analysisInvestigative Ophthalmology & Visual Science.  43:U891-U891. 2002
2002 Evaluation of tear film interference patterns and measures of tear break-up timeOptometry and Vision Science.  79:363-369. 2002
2001 The performance of the refractive status and vision profile survey in a contact lens clinical trialOphthalmology: Journal of The American Academy of Ophthalmology.  108:1160-1166. 2001
2001 Thickness of the pre- and post-lens tear film and of contact lenses measured by interferometry.Investigative Ophthalmology & Visual Science.  42:S595-S595. 2001
2000 Overnight Orthokeratology [1] (multiple letters)Optometry and Vision Science.  77:627-629. 2000
2000 Corneal scarring and vision in keratoconus: A baseline report from the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) studyCurrent Womens Health Reports.  19:804-812. 2000
2000 Frequency of dry eye diagnostic test procedures used in various modes of ophthalmic practiceCurrent Womens Health Reports.  19:477-482. 2000
2000 Asymmetry in keratoconusInvestigative Ophthalmology & Visual Science.  41:S678-S678. 2000
2000 Daily disposable vs. disposable extended wear: A contact lens clinical trialOptometry and Vision Science.  77:637-647. 2000
2000 Overnight Orthokeratology: Authors’ ResponseOptometry and Vision Science.  77:628-629. 2000
2000 Overnight orthokeratologyOptometry and Vision Science.  77:252-259. 2000
1999 Correlation of corneal scarring with clinical measures and patient outcomes at baseline in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) StudyInvestigative Ophthalmology & Visual Science.  40:S911-S911. 1999
1999 Overnight orthokeratologyInvestigative Ophthalmology & Visual Science.  40:S909-S909. 1999

Education And Training

  • Doctor of Philosophy in Vision Science / Physiological Optics, Ohio State University System : Columbus 2004
  • Master of Public Health in Epidemiology, Ohio State University System : Columbus 2002
  • Master of Sciences or Mathematics in Vision Science / Physiological Optics, Ohio State University System : Columbus 2000
  • Doctor of Optometry, Ohio State University System : Columbus 1999
  • Bachelor of Arts in Biology, Hope College 1995
  • Full Name

  • Jason Nichols