Selected Publications

Academic Article

Year Title Altmetric
2022 Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinomaLaboratory Investigation.  102:1236-1244. 2022
2022 Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine modelsJCI Insight.  7. 2022
2022 Mucus, commensals, and the immune systemGut Microbes.  14. 2022
2021 CD4+ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitisScience Immunology.  5. 2021
2021 Early life stress in mice alters gut microbiota independent of maternal microbiota inheritance 2021
2021 ICOS ligand and IL-10 synergize to promote host–microbiota mutualism 2021
2020 Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunityNature Communications.  11. 2020
2020 Bone marrow Tregs mediate stromal cell function and support hematopoiesis via IL-10JCI Insight.  5. 2020
2019 Cutting edge: ICOS-deficient regulatory T cells display normal induction of IL10 but readily downregulate expression of Foxp3Journal of Immunology.  202:1039-1044. 2019
2018 Intestinal microbiota and the immune system in metabolic diseases 2018
2017 TCR-independent functions of Th17 cells mediated by the synergistic actions of cytokines of the IL-12 and IL-1 familiesPLoS One.  12. 2017
2017 T Cell-derived IL-10 impairs host resistance to mycobacterium tuberculosis infectionJournal of Immunology.  199:613-623. 2017
2016 Colonization potential to reconstitute a microbe community in patients detected early after fecal microbe transplant for recurrent C. difficileBMC Microbiology.  16. 2016
2015 Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis 2015
2013 IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis 2013
2013 Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to porphyromonas gingivalisJournal of Leukocyte Biology.  93:21-31. 2013
2012 Acute gastrointestinal infection induces long-lived microbiota-specific T cell responsesScience.  337:1553-1556. 2012
2012 Reciprocal interactions of the intestinal microbiota and immune systemNature.  489:231-241. 2012
2011 Immunology: Context is key in the gutNature.  471:169-170. 2011
2011 Lineage-specific effects of 1,25-dihydroxyvitamin D3 on the development of effector CD4 T cellsJournal of Biological Chemistry.  286:997-1004. 2011
2009 Intestinal Effector T Cells in Health and DiseaseImmunity.  31:389-400. 2009
2009 Contrasting roles for all-trans retinoic acid in TGF-β-mediated induction of Foxp3 and Il10 genes in developing regulatory T cellsJournal of Experimental Medicine.  206:343-357. 2009
2009 Late Developmental Plasticity in the T Helper 17 LineageImmunity.  30:92-107. 2009
2008 Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulationImmunological Reviews.  226:219-233. 2008
2007 Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10Nature Immunology.  8:931-941. 2007


Year Title Altmetric
2015 Effector CD4+ T Cells in the Intestines.  721-732. 2015

Education And Training

  • Doctor of Philosophy in Microbiology, University of Alabama at Birmingham 2007
  • Bachelor of Science or Mathematics in Biology, Midwestern State University 2001
  • Full Name

  • Craig Maynard