Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Clinical correlates of the ability to consent to research participation in brain metastasis 2020
2020 Design and Rationale for First-in-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain TumorsHuman Gene Therapy.  31:1132-1139. 2020
2020 Interinstitutional Plan Quality Assessment of 2 Linac-Based, Single-Isocenter, Multiple Metastasis Radiosurgery TechniquesAdvances in Radiation Oncology.  5:1051-1060. 2020
2020 Capacity to consent to research participation in adults with metastatic cancer: Comparisons of brain metastasis, non-CNS metastasis, and healthy controls 2020
2020 Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424 2020
2020 Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience 2020
2020 Using a whiteboard web application for tracking treatment workflow metrics for dosimetrists and physiciansMedical Dosimetry.  45:73-76. 2020
2020 Using cognition to predict the ability to understand medical treatment in brain and metastatic cancer 2020
2020 Combined targeting of mutant p53 and jumonji family histone demethylase augments therapeutic efficacy of radiation in H3K27M DIPGInternational Journal of Molecular Sciences.  21. 2020
2020 Control and Toxicity in Melanoma Versus Other Brain Metastases in Response to Combined Radiosurgery and PD-(L)1 Immune Checkpoint InhibitionAdvances in Radiation Oncology2020
2020 Focal Management of Large Brain Metastases and Risk of Leptomeningeal DiseaseAdvances in Radiation Oncology.  5:34-42. 2020
2020 Multi-institutional validation of brain metastasis velocity, a recently defined predictor of outcomes following stereotactic radiosurgeryRadiotherapy and Oncology.  142:168-174. 2020
2020 Surface guided imaging during stereotactic radiosurgery with automated deliveryJournal of Applied Clinical Medical Physics2020
2019 Repeat gamma knife stereotactic radiosurgery in the treatment of trigeminal neuralgia: A single-center experience and focused review of the literatureJournal of Clinical Neuroscience.  70:102-107. 2019
2019 Feasibility of Dose Escalating [18F]fluciclovine Positron Emission Tomography Positive Pelvic Lymph Nodes During Moderately Hypofractionated Radiation Therapy for High-Risk Prostate CancerAdvances in Radiation Oncology.  4:649-658. 2019
2019 LINAC based stereotactic radiosurgery for multiple brain metastases: guidance for clinical implementationActa Oncologica.  58:1275-1282. 2019
2019 Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapiesGenes and Diseases.  6:232-246. 2019
2019 A multi-institutional analysis of presentation and outcomes for leptomeningeal disease recurrence after surgical resection and radiosurgery for brain metastasesNeuro-Oncology.  21:1049-1059. 2019
2019 Initial SRS for Patients With 5 to 15 Brain Metastases: Results of a Multi-Institutional Experience 2019
2019 Optical surface guidance for submillimeter monitoring of patient position during frameless stereotactic radiotherapyJournal of Applied Clinical Medical Physics.  20:91-98. 2019
2019 Diagnosing growth in low-grade gliomas with and without longitudinal volume measurements: A retrospective observational studyPLoS Medicine.  16. 2019
2019 Stereotactic radiosurgery with MLC-defined arcs: Verification of dosimetry, spatial accuracy, and end-to-end testsJournal of Applied Clinical Medical Physics.  20:84-98. 2019
2019 Pathologic Predictors of Local Recurrence in Atypical Meningiomas Following Gross Total Resection 2019
2019 Prostate Stereotactic Body Radiation Therapy With a Focal Simultaneous Integrated Boost: Acute Toxicity and Dosimetry Results From a Prospective TrialAdvances in Radiation Oncology.  4:90-95. 2019
2019 Treatment-induced remission of medulloblastoma using a chemotherapeutic regimen devoid of vincristine in a child with charcot–marie–tooth diseaseCurrent Oncology.  26:e266-e269. 2019
2018 Choosing Wisely at the End of Life: Use of Shorter Courses of Palliative Radiation Therapy for Bone Metastasis 2018
2018 The virtual cone: A novel technique to generate spherical dose distributions using a multileaf collimator and standardized control-point sequence for small target radiation surgeryAdvances in Radiation Oncology.  3:421-430. 2018
2018 Hospice care, cancer-directed therapy, and Medicare expenditures among older patients dying with malignant brain tumorsNeuro-Oncology.  20:986-993. 2018
2018 A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: Results of NRG Oncology RTOG 0913Neuro-Oncology.  20:666-673. 2018
2018 Postoperative radiosurgery for the treatment of metastatic brain tumor: Evaluation of local failure and leptomeningeal diseaseJournal of Clinical Neuroscience.  49:48-55. 2018
2018 Multi-institutional competing risks analysis of distant brain failure and salvage patterns after upfront radiosurgery without whole brain radiotherapy for brain metastasisAnnals of Oncology.  29:497-503. 2018
2018 Correction: Expert consensus on re-irradiation for recurrent glioma. [Radiat Oncol. 12, (194)] DOI: 10.1186/s13014-017-0928-3Radiation Oncology.  13. 2018
2018 Evaluation of multiple factors affecting normal brain dose in single-isocenter multiple target radiosurgeryJournal of Radiosurgery and SBRT.  5:131-144. 2018
2017 Expert consensus on re-irradiation for recurrent gliomaRadiation Oncology.  12. 2017
2017 Hospital-based end-of-life care and costs for older patients with malignant brain tumorsJAMA Oncology.  3:1581-1582. 2017
2017 Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogramJournal of Neuro-Oncology.  135:403-411. 2017
2017 Subcutaneous adipose tissue characteristics and the risk of biochemical recurrence in men with high-risk prostate cancerUrologic Oncology: Seminars and Original Investigations.  35:663.e15-663.e21. 2017
2017 Fractionated stereotactic radiation therapy for intact brain metastasesAdvances in Radiation Oncology.  2:564-571. 2017
2017 A priori patient-specific collision avoidance in radiotherapy using consumer grade depth cameras:Medical Physics.  44:3430-3436. 2017
2017 Gait Speed and Survival in Patients With Brain MetastasesJournal of Pain and Symptom Management.  54:105-109. 2017
2017 CT measures of bone mineral density and muscle mass can Be used to predict noncancer death in men with prostate cancerRadiology.  282:475-483. 2017
2017 Rationale and Design of a Phase 1 Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain Tumors 2017
2017 Rationale and Design of a Phase I Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain Tumors. 2017
2017 Distant brain recurrence in patients with five or more newly diagnosed brain metastases treated with focal stereotactic radiotherapy alone.Journal of Radiosurgery and SBRT.  4:255-263. 2017
2016 An Automated Approach to High-Quality Single-Isocenter Volumetric Modulated Arc Therapy Stereotactic Radiosurgery Treatment Planning on a Linear Accelerator. 2016
2016 Analysis of Predictive Factors for Acute Esophagitis in Lung Cancer Radiation Therapy. 2016
2016 Analysis of Predictive Factors for Pneumonitis in Lung Cancer Radiation Therapy. 2016
2016 Combining Computed Tomography-Based Bone Density Assessment with FRAX Screening in Men with Prostate CancerJournal of Clinical Densitometry.  19:430-435. 2016
2016 Coneless Linear Accelerator-Based Volumetric Modulated Arc Therapy Stereotactic Radiosurgery Technique for Functional Disorders. 2016
2016 Distant Brain Recurrence in Patients With 5 or More Newly Diagnosed Brain Metastases Treated With Stereotactic Radiosurgery (SRS) or Fractionated Stereotactic Radiation Therapy (FSRT) Alone. 2016
2016 Interinstitutional Dosimetric Comparison Between Stereotactic Radiosurgery and Volumetric Modulated Arc Therapy Radiosurgery for Difficult Intracranial Cases. 2016
2016 Multi-Institutional Competing Risks Analysis Predicting Distant Brain Failure and Salvage Patterns After Upfront Radiosurgery Without Whole-Brain Radiation Therapy for Brain Metastasis. 2016
2016 Stereotactic Hypofractionated Radiation Therapy for Intact Brain Metastases. 2016
2016 Radiation therapy for glioblastoma: Executive summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice GuidelinePractical Radiation Oncology.  6:217-225. 2016
2016 SU-F-E-07: Web-Based Training for Radiosurgery: Methods and Metrics for Global Reach.Medical Physics.  43:3354. 2016
2016 SU-F-J-96: Comparison of Frame-Based and Mutual Information Registration Techniques for CT and MR Image Sets.Medical Physics.  43:3428-3429. 2016
2016 SU-F-T-629: Effect of Multi-Leaf Collimator (MLC) Width On Plan Quality of Single-Isocenter VMAT Intracranial Stereotactic Radiosurgery for Multiple Metastases.Medical Physics.  43:3608. 2016
2016 SU-F-T-637: Single-Isocenter Versus Multiple-Isocenter VMAT SRS for Unusual Multiple Metastasis Case with Two Widely Separated Lesions.Medical Physics.  43:3610. 2016
2016 Quality of Prostate Cancer Treatment Information on Cancer Center Websites.Cureus.  8:e580. 2016
2016 A phase 2 study of radiosurgery and temozolomide for patients with 1 to 4 brain metastasesAdvances in Radiation Oncology.  1:83-88. 2016
2016 Pelvic radiotherapy versus radical prostatectomy with limited lymph node sampling for high-grade prostate adenocarcinomaProstate Cancer.  2016. 2016
2016 Radiosurgery of brain metastases - How many is too many?Journal of Radiosurgery and SBRT.  4:5-6. 2016
2015 Capacity of patients with brain metastases to make treatment decisions 2015
2015 Increased radiation dose heterogeneity within the prostate predisposes to urethral strictures in patients receiving moderately hypofractionated prostate radiation therapyPractical Radiation Oncology.  5:338-342. 2015
2015 In Reply: Volumetric Arc Therapy (RapidArc) vs Gamma Knife Radiosurgery for Multiple Brain Metastases: Not only a Dosimetric IssueNeurosurgery.  77:E311. 2015
2015 Cognitive Predictors of Reasoning through Treatment Decisions in Patients with Newly Diagnosed Brain MetastasesJournal of the International Neuropsychological Society.  21:412-418. 2015
2015 KINOMIC ALTERATIONS IN ATYPICAL MENINGIOMA.Medical research archives.  2015. 2015
2015 Cognitive predictors of understanding treatment decisions in patients with newly diagnosed brain metastasisCancer.  121:2013-2019. 2015
2015 Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomasJournal of Neuro-Oncology.  122:585-593. 2015
2015 Continuous chemoradiation following complete response to neo-adjuvant chemotherapy provides improved outcomes in muscle invasive urothelial carcinomaJournal of Solid Tumors.  5:59-68. 2015
2015 In reply: Volumetric arc therapy (RapidArc) vs Gamma knife radiosurgery for multiple brain metastasesNeurosurgery.  76:E353-E354. 2015
2014 Hypofractionated stereotactic radiosurgery with concurrent bevacizumab for recurrent malignant gliomas: The University of Alabama at Birmingham experience 2014
2014 Cognition in patients with newly diagnosed brain metastasis: Profiles and implicationsJournal of Neuro-Oncology.  120:179-185. 2014
2014 Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomideRadiation Oncology.  9. 2014
2014 Different rectal toxicity tolerance with and without simultaneous conventionally-fractionated pelvic lymph node treatment in patients receiving hypofractionated prostate radiotherapyRadiation Oncology.  9. 2014
2014 SU-E-T-425: Spherical Dose Distributions for Radiosurgery Using a Standardized MLC Plan.Medical Physics.  41:323. 2014
2014 A phase 1 trial of oncolytic HSV-1, g207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responsesMolecular Therapy.  22:1048-1055. 2014
2014 Beam geometry selection using sequential beam additionMedical Physics.  41. 2014
2014 Comparison of plan quality and delivery time between volumetric arc therapy (rapidarc) and gamma knife radiosurgery for multiple cranial metastasesNeurosurgery.  75:409-417. 2014
2014 PSA response to neoadjuvant androgen deprivation is an independent prognostic marker and may identify patients who benefit from treatment escalationUrologic Oncology: Seminars and Original Investigations.  32:687-693. 2014
2014 Reduced radiation tolerance of penile structures associated with dose-escalated hypofractionated prostate radiotherapyUrology.  84:1383-1388. 2014
2013 Effects of flattening filter-free and volumetric-modulated arc therapy delivery on treatment efficiency.Journal of Applied Clinical Medical Physics.  14:4328. 2013
2013 Stereotactic body radiation therapy (SBRT) for lung malignancies: Preliminary toxicity results using a flattening filter-free linear accelerator operating at 2400 monitor units per minuteRadiation Oncology.  8. 2013
2013 Efficacy and toxicity of conventionally fractionated pelvic radiation with a hypofractionated simultaneous versus conventionally fractionated sequential boost for patients with high-risk prostate cancerActa Oncologica.  52:1181-1188. 2013
2013 The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancerJournal of Neuro-Oncology.  112:467-472. 2013
2013 Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resectionJournal of Pediatric Hematology/Oncology.  35. 2013
2013 Patient benefit from salvage radiation for prostate cancer.Journal of Clinical Oncology.  31:175. 2013
2013 Effects of flattening filter-free and volumetric-modulated arc therapy delivery on treatment efficiencyJournal of Applied Clinical Medical Physics.  14:155-166. 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:4126. 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:64-71. 2013
2013 Optimal planning target volume margins for elective pelvic lymphatic radiotherapy in high-risk prostate cancer patients.ISRN Oncology.  2013:941269. 2013
2013 SU‐E‐T‐673: Factors Influencing Normal Brain Dose for Single‐Isocenter Multi‐Target RadiosurgeryMedical Physics.  40:361. 2013
2012 In Regard to Yamamoto et al 2012
2012 Plan quality and treatment planning technique for single isocenter cranial radiosurgery with volumetric modulated arc therapyPractical Radiation Oncology.  2:306-313. 2012
2012 Reply to M.C. Chamberlain et alJournal of Clinical Oncology.  30:3316-3317. 2012
2012 Stereotactic radiosurgical treatment of brain metastasis of primary tumors that rarely metastasize to the central nervous systemJournal of Neuro-Oncology.  109:513-519. 2012
2012 Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases 2012
2012 Summary report on the graded prognostic assessment: An accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastasesJournal of Clinical Oncology.  30:419-425. 2012
2012 Hypofractionated Prostate Radiotherapy with or without Conventionally Fractionated Nodal Irradiation: Clinical Toxicity Observations and Retrospective Daily Dosimetry.Prostate Cancer.  2012:546794. 2012
2012 SU‐E‐T‐631: Beam Geometry Selection Using Sequential Beam AdditionMedical Physics.  39:3851. 2012
2011 Reply to Drs. mulvenna and holt 2011
2011 Response to radiation in renal medullary carcinomaRare Tumors.  3:100-103. 2011
2011 Gene expression analysis in radiotherapy patients and C57BL/6 mice as a measure of exposure to ionizing radiationRadiation Research.  176:49-61. 2011
2011 Efficacy and rectal toxicity of hypofractionated radiation therapy with daily image guidance.Journal of Clinical Oncology.  29:85. 2011
2011 Dosimetric analysis of imaging changes following pulmonary stereotactic body radiation therapy 2011
2011 Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide 2011
2011 Improved clinical efficiency in CNS stereotactic radiosurgery using a flattening filter free linear accelerator.Journal of Radiosurgery and SBRT.  1:117-122. 2011
2010 Radiotherapy for soft tissue sarcoma of the proximal lower extremitySarcoma.  2010. 2010
2010 Management of brain metastasesCurrent Treatment Options in Neurology.  12:334-346. 2010
2010 Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients 2010
2010 Rationally designed pharmacogenomic treatment using concurrent capecitabine and radiotherapy for glioblastoma; gene expression profiles associated with outcomeClinical Cancer Research.  16:2890-2898. 2010
2010 RapidArc Radiation Therapy: First Year Experience at the University of Alabama at Birmingham 2010
2010 A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastomaArchives of Neurology.  67:313-319. 2010
2010 Feasibility of Single-Isocenter Volumetric Modulated Arc Radiosurgery for Treatment of Multiple Brain Metastases 2010
2010 Impact of Dose Rate on Outcomes of Gamma Knife® Radiosurgery in Patients with Face PainRadiosurgery.  7:360-365. 2010
2010 Stereotactic body radiation therapy for liver metastases and primary hepatocellular carcinoma: Normal tissue tolerances and toxicityCancer Control : Journal of the Moffitt Cancer Center.  17:111-119. 2010
2009 Bi- and tri-exponential fitting to TG-43 radial dose functions of brachytherapy sources based on a genetic algorithmBrachytherapy.  8:361-366. 2009
2009 In Reply to Drs. Larson and Sahgal 2009
2009 Development of an accelerated GVF semi-automatic contouring algorithm for radiotherapy treatment planningComputers in Biology and Medicine.  39:650-656. 2009
2009 A phase I evaluation of intravenous (IV) (131)I-chlorotoxin delivery to solid peripheral and intracranial tumors.Journal of Clinical Oncology.  27:e14507. 2009
2009 A phase I study of ABT 510 and concurrent temozolamide and radiotherapy for patients with newly diagnosed glioblastoma multiforme.Journal of Clinical Oncology.  27:2023. 2009
2009 Dosimetry study of a phase II multiple-dose intracavitary administration of (131)I-TM601 in adult patients with recurrent high-grade glioma.Journal of Clinical Oncology.  27:e13006. 2009
2009 NABTT-0702: A phase II study of R-(-)-gossypol (AT-101) in recurrent glioblastoma multiforme (GBM).Journal of Clinical Oncology.  27:2010. 2009
2008 In Reply to Dr. Speer 2008
2008 Hitting a moving target: Evolution of a treatment paradigm for atypical meningiomas amid changing diagnostic criteriaNeurosurgical Focus.  24. 2008
2008 Enhancement of Glioma Radiotherapy and Chemotherapy Response With Targeted Antibody Therapy Against Death Receptor 5 2008
2008 An imrt technique to increase therapeutic ratio of breast irradiation in patients with early-stage left breast cancer: limiting second malignanciesMedical Dosimetry.  33:71-77. 2008
2008 Prognostic factors and preoperative radiation therapy associated with sphincter preservation in patients with resectable rectal cancer 2008
2008 Predictors of Distant Brain Recurrence for Patients With Newly Diagnosed Brain Metastases Treated With Stereotactic Radiosurgery Alone 2008
2007 Vacuum-assisted closure for radiation-associated wound complicationsJournal of Surgical Oncology.  96:575-582. 2007
2007 A Dosimetric Comparison of Electronic Compensation, Conventional Intensity Modulated Radiotherapy, and Tomotherapy in Patients With Early-Stage Carcinoma of the Left Breast 2007
2007 Intensity modulation with respiratory gating for radiotherapy of the pleural spaceMedical Dosimetry.  32:16-22. 2007
2007 Effect of beam number on organ-at-risk sparing in dynamic multileaf collimator delivery of intensity modulated radiation therapyMedical Physics.  34:3752-3759. 2007
2007 SU‐FF‐J‐78: 3‐D Target Localization at the End of Expiration Prior to Respiration‐Gated Radiotherapy TreatmentMedical Physics.  34:2386. 2007
2007 SU‐FF‐T‐372: Registration of Frameless High‐Field MRI to Low‐Field Frame‐Based MRI Images in Leksell Gamma‐Knife (LGK) RadiosurgeryMedical Physics.  34:2487. 2007
2007 TH‐C‐AUD‐03: Impact of Respiratory Motion On Helical Tomotherapy Dose Delivery: A Phantom Study with 3‐D Volumetric Dose MeasurementsMedical Physics.  34:2626-2627. 2007
2006 Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade gliomaJournal of Clinical Oncology.  24:3644-3650. 2006
2006 Radiation therapy for retroperitoneal sarcoma 2006
2006 Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: Results of North Central Cancer Treatment Group protocol N0177 2006
2006 Preoperative radiation therapy with selective dose escalation to the margin at risk for retroperitoneal sarcomaCancer.  107:371-379. 2006
2006 An IMRT technique to increase therapeutic ratio of breast irradiation in patients with early stage left breast cancer: Limiting second malignancies.Journal of Clinical Oncology.  24:10791. 2006
2006 Safety and tolerance of multiple weekly intracavitary injections of 131I-chlorotoxin (TM-601): Preliminary results of a prospective clinical trial in patients with recurrent glioblastoma multiforme.Journal of Clinical Oncology.  24:1555. 2006
2006 Dosimetric and radiobiological impact of dose fractionation on respiratory motion induced IMRT delivery errors: A volumetric dose measurement studyMedical Physics.  33:1380-1387. 2006
2006 Implementation of Talairach atlas based automated brain segmentation for radiation therapy dosimetryTechnology in Cancer Research and Treatment.  5:15-21. 2006
2005 Imaging glioma extent with 131I-TM-601Journal of Nuclear Medicine.  46:580-586. 2005
2005 Phase I study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: Expression analysis of genes related to outcomeJournal of Clinical Oncology.  23:8679-8687. 2005
2005 Treatment of adults with recurrent malignant glioma 2005
2005 TRAIL death receptor therapy for malignant glioma.Journal of Clinical Oncology.  23:3187. 2005
2005 SU‐FF‐J‐123: Residual Tumor Motion in Respiratory Gated CT Treatment PlaningMedical Physics.  32:1948. 2005
2005 Simultaneous optimization of sequential IMRT plansMedical Physics.  32:3257-3266. 2005
2004 IMRT dose escalation for positive para-aortic lymph nodes in patients with locally advanced cervical cancer while reducing dose to bone marrow and other organs at risk 2004
2004 Radionecrosis of the inferior occipital lobes with altitudinal visual field loss after gamma knife radiosurgeryJournal of Neuro-Ophthalmology.  24:195-199. 2004
2004 Initial treatment of melanoma brain metastases using gamma knife radiosurgery: An evaluation of efficacy and toxicityCancer.  101:825-833. 2004
2004 Refining the staging evaluation of pineal regoin germinoma using neuroendoscopy and the presence of preoperative diabetes insipidusNeuro-Oncology.  6:127-133. 2004
2004 Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells 2004
2004 Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression 2004
2004 Brain metastasesCurrent Problems in Surgery.  41:665-741. 2004
2003 Dosimetric effect of respiration-gated beam on IMRT deliveryMedical Physics.  30:2241-2252. 2003
2003 Bulb of penis as a marker for prostatic apex in external beam radiotherapy of prostate cancer 2003
2003 Adding androgen suppression to radiotherapy may improve disease-free survival over radiotherapy alone in locally advanced prostate cancer.Cancer Treatment Reviews.  29:227-229. 2003
2003 Role of radiation therapy and radiosurgery in glioblastoma multiforme 2003
2003 Validation of target volume and position in respiratory gated CT planning and treatmentMedical Physics.  30:3196-3205. 2003
2002 Effect of multileaf collimator leaf width on physical dose distributions in the treatment of CNS and head and neck neoplasms with intensity modulated radiation therapyMedical Physics.  29:1116-1119. 2002
2001 Balancing the possible effectiveness of postoperative radiotherapy for non-small-cell lung cancer against the possible detriment of radiation-induced toxicityJournal of Clinical Oncology.  19:3905-3907. 2001
2001 Effect of Foley catheters on seed positions and urethral dose in 125I and 103Pd prostate implants 2001
2001 Multimodality treatment of merkel cell carcinoma: Case series and literature review of 1024 casesAnnals of Surgical Oncology.  8:204-208. 2001
2000 A prospective evaluation of the timing of postoperative radiotherapy for preventing heterotopic ossification following traumatic acetabular fractures 2000
2000 3D conformal radiation therapy (3DCRT) for high grade prostate cancer: A multi-institutional review 2000
2000 Effects of pelvic rotation and needle angle on pubic arch interference during transperineal prostate implants 2000
2000 In vivo urethral dose measurements: A method to verify high dose rate prostate treatmentsMedical Physics.  27:2297-2301. 2000
1998 Controversies in the Management of Stage I Seminoma 1998

Chapter

Year Title Altmetric
2018 Linac-based stereotactic radiosurgery and hypofractionated stereotactic radiotherapy.  639-663. 2018
2010 Dosimetry for Targeted Radiotherapy.  473-506. 2010
2010 Impact of dose rate on outcomes of Gamma Knife® radiosurgery in patients with face pain.  360-365. 2010

Research Overview

  • My research interests include clinical trials of novel therapeutics in combination with radiation therapy particularly in the treatment of brain and prostate tumors. In addition, I have been very involved in treatment planning research and education for IMRT and IGRT
  • Investigator On

  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group 2019 - 2024
  • NRG Oncology Member Institution Clinical Trial Fixed Price Subaward Agreement  awarded by NRG ONCOLOGY FOUNDATION 2019 - 2024
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2019 - 2023
  • Private Grant  awarded by ELI LILLY AND COMPANY 2020 - 2023
  • A Randomized Multi-Center Phase III Study of Individualized Sterotactic Body Radiation Therapy (SRBT) versus Trans-Arterial Chemoembolization (TACE) as a Bridge to Transplant in Hepatocellular Carcinoma  awarded by LAHEY CLINIC, INC. 2020 - 2022
  • Ph1 Study of HSV G207 in Pediatric Malignant Cerebellar Tumors IND 16294 01/05/18  awarded by Food & Drug Administration 2019 - 2022
  • Phase 1 Trial of Engineered HSV G207 in Children with Malignant Cerebellar Brain Tumors  awarded by CANNONBALL KIDS' CANCER FOUNDATION 2019 - 2022
  • RTOG Foundation Master Service Agreement for Participation in Foundation Research: RTOG 3501 Tryhard: A Phase II, Randomized, Double Blind, Placebo-Controlled Study of Lapatinib (Tykerb) for Non-HPV Locally Advanced Head and Neck Cancer with Concurrent Chemoradiation  awarded by American College of Radiology 2012 - 2022
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2018 - 2022
  • Private Grant  awarded by IN8BIO INC. 2020 - 2022
  • Private Grant  awarded by NOVOCURE, INC. 2019 - 2022
  • A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer  awarded by University of Florida 2020 - 2021
  • COMPLETED - Comprehensive Cancer Center Core Support Grant - Clinical Protocol and Data Management Shared Facility  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Comprehensive Cancer Center Core Support Grant - Clinical Protocol and Data Management Shared Facility  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Comprehensive Cancer Center Core Support Grant - Protocol Review and Monitoring System  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Pragmatic Phase III Randomized Trial of Proton vs. Photon Therapy for Patients with Non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial  awarded by University of Pennsylvania 2019 - 2020
  • Ph1 of HSV G207 and Radiation to Treat Pediatric Brain Tumors IND 16294 (12/10/14)  awarded by Food & Drug Administration 2016 - 2020
  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group 2014 - 2020
  • Decisional Capacity Evaluation in Metastatic Brain Cancer  awarded by American Cancer Society, Inc. 2015 - 2019
  • Private Grant  awarded by PROSTATE CANCER CLINICAL TRIALS CONSORTIUM, LLC 2017 - 2019
  • UAB NRG Oncology Master Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2019
  • UAB NRG Oncology Member Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2015 - 2019
  • UAB NRG Oncology Member Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2014 - 2019
  • Pilot Study of HSV G207 Alone or with Radiation in Children with Recurrent Brain Tumors  awarded by KAUL PEDIATRIC RESEARCH INSTITUTE 2015 - 2018
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2018
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2014 - 2017
  • Radiosurgery vs. Lobectomy for Temporal Epilepsy: Phase 3 Clinical Trial  awarded by University of California 2011 - 2017
  • COMPLETED - Comprehensive Cancer Center Core Support Grant - Clinical Protocol and Data Management Shared Facility  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Private Grant  awarded by SPECTRUM PHARMACEUTICALS, INC. 2013 - 2016
  • Private Grant  awarded by ABBOTT LABORATORIES 2012 - 2014
  • ACRIN 6684: Phase II Assessment of Tumor Hypoxia in Glioblastoma Using FMISO with PET and MRI (R09-185)  awarded by American College of Radiology 2010 - 2014
  • Private Grant  awarded by EMD SERONO 2009 - 2013
  • Private Grant  awarded by EMD SERONO 2009 - 2013
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2008 - 2013
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2006 - 2012
  • Teaching Activities

  • STP299CU - Research: Radiation Therapy for Metastic Brain Tumors (Fall Term 2018) 2018
  • STP299AN - RADIATION ONCOLOGY IMMERSION AND RESEARCH (Fall Term 2017) 2017
  • BME799 - Dissertation Research (Fall Term 2013) 2013
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2013) 2013
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2013) 2013
  • BME799 - Dissertation Research (Summer Term 2013) 2013
  • BME799 - Dissertation Research (Spring Term 2013) 2013
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2013) 2013
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2013) 2013
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2013) 2013
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-404 - RADIATION ONCOLOGY RESEARCH (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2012) 2012
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2011) 2011
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2010) 2010
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2009) 2009
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2009) 2009
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2009) 2009
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2009) 2009
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2009) 2009
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2009) 2009
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2008) 2008
  • 76-404 - RADIATION ONCOLOGY RESEARCH ELECTIVE (Fall Term 2008) 2008
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2008) 2008
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2008) 2008
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2008) 2008
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2008) 2008
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2008) 2008
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007 - 2008
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007
  • 76-404 - RADIATION ONCOLOGY RESEARCH ELECTIVE (Fall Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007
  • 76-404 - RADIATION ONCOLOGY RESEARCH ELECTIVE (Fall Term 2007) 2007
  • 76-404 - RADIATION ONCOLOGY RESEARCH ELECTIVE (Fall Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Fall Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2007) 2007
  • 76-403 - RADIATION ONCOLOGY (Spring Term 2007) 2007
  • Education And Training

  • Doctor of Medicine, Medical College of Georgia 1993
  • Memorial Medical Center, Internship 1994
  • Medical College of Georgia, Residency 1997
  • University of Michigan Hospitals & Health Centers, Postdoctoral Fellowship 1998
  • Full Name

  • John Fiveash