Baddley, John

Baddley, John
Professor

Professor (P), Medicine - Infectious Diseases , Department of Medicine 2002 -
Assistant Professor (S), Critical Care (Retired Org) , School of Health Professions 2006 -
Senior Scientist (C), Center for Outcomes and Effectiveness Research and Education (COERE) , General Clinical Research Center 2012 -

Overview

Dr. Baddley is Associate Professor of Medicine in the Division of Infectious Diseases at the University of Alabama at Birmingham. He serves as Director of the Transplant ID Clinic at UAB. He is also Chief of Infectious Diseases at Birmingham VA Medical Center and Director of the VA Infection Control Program. Dr. Baddley’s research interests include the epidemiology, diagnosis and treatment of fungal infections; transplant infectious diseases; and hospital infection control.

Selected Publications

Academic Article

Year	Title	Altmetric
2019	Cryptococcosis in solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice 2019
2019	Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology 2019
2018	Mapping Histoplasma capsulatum exposure, United States 2018
2018	Effect of algorithm-based therapy vs usual care on clinical success and serious adverse events in patients with staphylococcal bacteremia a randomized clinical trial 2018
2018	ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Soluble immune effector molecules [I]: anti-tumor necrosis factor-α agents) 2018
2018	Effect of pulsed xenon ultraviolet room disinfection devices on microbial counts for methicillin-resistant Staphylococcus aureus and aerobic bacterial colonies 2018
2018	Human polyomavirus-7–associated eruption successfully treated with acitretin 2018
2018	Pneumocystis and glucocorticoid use: To prophylax or not to prophylax (and when?); That is the question 2018
2018	Central nervous system histoplasmosis 2018
2018	Epidemiology of Histoplasmosis 2018
2018	Two cases and a review of graft-versus-host disease and the role of hepatitis C treatment in liver transplant patients 2018
2017	Community characteristics and regional variations in sepsis 2017
2017	Association of baseline steroid use with long-term rates of infection and sepsis in the REGARDS cohort 2017
2017	Longterm effectiveness of herpes zoster vaccine among patients with autoimmune and inflammatory diseases 2017
2017	Application of the Third International Consensus Definitions for Sepsis (Sepsis-3) Classification: a retrospective population-based cohort study 2017
2017	Safety of biologic and nonbiologic disease-modifying antirheumatic drug therapy in veterans with rheumatoid arthritis and hepatitis c virus infection 2017
2017	Association of Diabetes and Insulin Therapy With Risk of Hospitalization for Infection and 28-Day Mortality Risk. 2017
2017	Association of diabetes and insulin therapy with risk of hospitalization for infection and 28-day mortality risk 2017
2017	Herpes Zoster and the Risk of Stroke in Patients With Autoimmune Diseases 2017
2017	Opportunistic Infections in Biological Therapy, Risk and Prevention 2017
2017	A Mycoses Study Group International Prospective Study of Phaeohyphomycosis: An Analysis of 99 Proven/Probable Cases. 2017
2016	The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET) 2016
2016	Hemostasis biomarkers and risk of sepsis: the REGARDS cohort 2016
2016	Antistaphylococcal β-lactams versus vancomycin for treatment of infective endocarditis due to methicillin-susceptible coagulase-negative staphylococci: A prospective cohort study from the international collaboration on endocarditis 2016
2016	The risk of hospitalized infection following initiation of biologic agents versus methotrexate in the treatment of juvenile idiopathic arthritis 2016
2016	Analysis of health care claims during the peri-transfer stage of transition from pediatric to adult care among juvenile idiopathic arthritis patients 2016
2016	Risk of Herpes Zoster in Autoimmune and Inflammatory Diseases: Implications for Vaccination 2016
2016	Approach to the Solid Organ Transplant Patient with Suspected Fungal Infection 2016
2016	Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): A phase 3, randomised-controlled, non-inferiority trial 2016
2016	Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: Data from the National Veterans Health Administration 2016
2016	Comparative Risk of Hospitalized Infection Associated with Biologic Agents in Rheumatoid Arthritis Patients Enrolled in Medicare 2016
2016	Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis: A retrospective observational cohort study of the Mycoses Study Group (MSG-12) 2016
2016	Inpatient mortality among solid organ transplant recipients hospitalized for sepsis and severe sepsis 2016
2016	Validated risk score for predicting 6-month mortality in infective endocarditis 2016
2015	Opportunistic infections and biologic therapies in immune-mediated inflammatory diseases: Consensus recommendations for infection reporting during clinical trials and postmarketing surveillance 2015
2015	Pneumocystis Pneumonia in Solid Organ Transplant Recipients 2015
2015	Black-white racial disparities in sepsis: A prospective analysis of the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort 2015
2015	Fungal Infections in the Era of Biologic Therapies 2015
2015	Safety of biologic and nonbiologic disease-modifying antirheumatic drug therapy in veterans with rheumatoid arthritis and hepatitis B virus infection: A retrospective cohort study 2015
2015	Candida infective endocarditis: An observational cohort study with a focus on therapy 2015
2015	An evolving plaque in an immunosuppressed patient with psoriasis 2015
2015	Discharge diagnoses versus medical record review in the identification of community-acquired sepsis 2015
2015	One-year outcome following biological or mechanical valve replacement for infective endocarditis 2015
2015	Association between surgical indications, operative risk, and clinical outcome in infective endocarditis a prospective study from the international collaboration on endocarditis 2015
2015	Hospital-onset Clostridium difficile infection among solid organ transplant recipients 2015
2015	Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis: Analysis in the international collaboration of endocarditis-prospective cohort study 2015
2015	Loss of vancomycin-resistant enterococcus fecal dominance in an organ transplant patient with Clostridium difficile colitis after fecal microbiota transplant 2015
2015	Ocular bartonellosis in transplant recipients: Two case reports and review of the literature 2015
2015	Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET) 2015
2015	Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus 2015
2015	Risks of herpes zoster in patients with rheumatoid arthritis according to biologic disease-modifying therapy 2015
2014	Non-viral opportunistic infections in new users of tumour necrosis factor inhibitor therapy: Results of the SAfety assessment of biologic ThERapy (SABER) study 2014
2014	MORTALITY AFTER CLINICAL MANAGEMENT OF AIDS-ASSOCIATED CRYPTOCOCCAL MENINGITIS IN KENYA 2014
2014	Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy 2014
2014	Antibiotic utilization for acute respiratory tract infections in U.S. emergency departments 2014
2014	Immunosuppression regimen and the risk of acute rejection in HIV-infected kidney transplant recipients 2014
2014	A case report of progressive multifocal leucoencephalopathy (PML) associated with adalimumab 2014
2014	Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET) 2014
2014	Epidemiology of invasive mold infections in lung transplant recipients 2014
2014	Histoplasmosis in patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS): Multicenter study of outcomes and factors associated with relapse 2014
2014	Mollaret's meningitis 2014
2014	Physical inactivity and long-term rates of community-acquired sepsis 2014
2014	Pneumocystis jirovecii Pneumonia in Patients Receiving Tumor-Necrosis-Factor-Inhibitor Therapy: Implications for Chemoprophylaxis 2014
2014	Race and invasive fungal infection in solid organ transplant recipients 2014
2014	Reduction in false-positive aspergillus serum galactomannan enzyme immunoassay results associated with use of piperacillin-tazobactam in the United States 2014
2014	Reply to "acute sinusitis and pharyngitis as inappropriate indications for antibiotic use" 2014
2014	Risk of hospitalized bacterial infections associated with biologic treatment among US veterans with rheumatoid arthritis 2014
2014	Transmission of Balamuthia mandrillaris through solid organ transplantation: Utility of organ recipient serology to guide clinical management 2014
2013	Epidemiologic research of invasive fungal infections using large healthcare databases 2013
2013	Histoplasmosis after solid organ transplant 2013
2013	Infectious complications of immune modulatory agents 2013
2013	Sexual history taking and sexually transmitted infection screening in patients initiating erectile dysfunction medication therapy 2013
2013	HACEK Infective Endocarditis: Characteristics and Outcomes from a Large, Multi-National Cohort 2013
2013	Reply to oude lashof and vogelaers 2013
2013	Brief report: Incidence of selected opportunistic infections among children with juvenile idiopathic arthritis 2013
2013	Predictors of Mortality and Differences in Clinical Features among Patients with Cryptococcosis According to Immune Status 2013
2013	Association between the initiation of anti-tumor necrosis factor therapy and the risk of herpes zoster 2013
2013	Cryptococcosis in solid organ transplantation 2013
2013	Aspergillosis in Intensive Care Unit (ICU) patients: Epidemiology and economic outcomes 2013
2013	Influence of the timing of cardiac surgery on the outcome of patients with infective endocarditis and stroke 2013
2013	Antifungal therapy and length of hospitalization in transplant patients with invasive aspergillosis 2013
2013	How i treat histoplasmosis 2013
2013	Initiation of anti-TNF therapy and the risk of optic neuritis: From the safety assessment of biologic ThERapy (SABER) study 2013
2013	Mycobacterial diseases and antitumour necrosis factor therapy in USA 2013
2012	Cross-reactivity of Aspergillus galactomannan in an HIV-infected patient with histoplasmosis 2012
2012	Pneumocystis pneumonia in hospitalized patients: A detailed examination of symptoms, management, and outcomes in human immunodeficiency virus (HIV)-infected and HIV-uninfected persons 2012
2012	Use of a disease risk score to compare serious infections associated with anti-tumor necrosis factor therapy among high-versus lower-risk rheumatoid arthritis patients 2012
2012	Reply to Anaissie and Nucci and to Cisneros et al 2012
2012	Fatal burkholderia gladioli infection misidentified as empedobacter brevis in a lung transplant recipient with cystic fibrosis 2012
2012	Rates of hospitalized bacterial infection associated with juvenile idiopathic arthritis and its treatment 2012
2012	Association between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection among Older Patients with Selected Immune-Mediated Diseases 2012
2012	Association between Vancomycin-resistant enterococci bacteremia and ceftriaxone usage 2012
2012	Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: A patient-level quantitative review of randomized trials 2012
2012	Incidence and risk factors for progressive multifocal leukoencephalopathy among patients with selected rheumatic diseases 2012
2012	In response 2012
2012	Subcutaneous fungal infections 2012
2011	Pulmonary cryptococcosis 2011
2011	Pulmonary fungal infections 2011
2011	Fungal endocarditis 2011
2011	Initiation of tumor necrosis factor-αantagonists and the risk of hospitalization for infection in patients with autoimmune diseases 2011
2011	The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: A longitudinal observational study 2011
2011	Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis 2011
2011	Antifungal susceptibilities of Cryptococcus neoformans cerebrospinal fluid isolates from AIDS patients in Kenya 2011
2011	Geographic distribution of endemic fungal infections among older persons, United States 2011
2011	Observational study of the epidemiology and outcomes of vancomycin-resistant Enterococcus bacteraemia treated with newer antimicrobial agents 2011
2011	In Vitro echinocandin susceptibility of Aspergillus isolates from patients enrolled in the transplant-associated infection surveillance network 2011
2011	The comparative risk of serious infections among rheumatoid arthritis patients starting or switching biological agents 2011
2011	Comparison of in vitro susceptibility characteristics of Candida species from cases of invasive candidiasis in solid organ and stem cell transplant recipients: Transplant-Associated Infections Surveillance Network (TRANSNET), 2001 to 2006 2011
2011	Antifungal prophylaxis in solid organ transplant recipients 2011
2011	Clinical risk factors for invasive aspergillosis 2011
2011	Histoplasma antigen clearance during treatment of histoplasmosis in patients with AIDS determined by a quantitative antigen enzyme immunoassay 2011
2011	Transmission of Cryptococcus neoformans by organ transplantation 2011
2011	Aspergillus terreus accessory conidia are multinucleated, hyperpolarizing structures that display differential dectin staining and can induce heightened inflammatory responses in a pulmonary model of aspergillosis 2011
2011	Aspergillus terreus accessory conidia are multinucleated, hyperpolarizing structures that display differential dectin staining and can induce heightened inflammatory responses in a pulmonary model of aspergillosis. 2011
2011	Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006 2011
2010	Epidemiology of emerging fungi and fungi-like organisms 2010
2010	Factors associated with mortality in transplant patients with invasive aspergillosis 2010
2010	Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: Overview of the transplant- associated infection surveillance network (TRANSNET) database 2010
2010	The prevalence, clinical features, risk factors and outcome associated with cryptococcal meningitis in HIV positive patients in Kenya. 2010
2009	Molecular identification of Aspergillus species collected for the transplant-associated infection surveillance network 2009
2009	Patterns of susceptibility of Aspergillus isolates recovered from patients enrolled in the transplant-associated infection surveillance network 2009
2009	Cryptococcal disease presenting as necrotizing cellulitis in transplant recipients: Case report 2009
2009	Pinpointing prognostic indicators of fungal infections in transplant patients 2009
2009	A multicenter, double-blind trial of a high-dose caspofungin treatment regimen versus a standard caspofungin treatment regimen for adult patients with invasive candidiasis 2009
2009	Authors' reply 2009
2009	Aspergillus alabamensis, a new Clinically relevant species in the section terre 2009
2009	Cryptococcal lung disease 2009
2008	Histoplasmosis in HIV-infected patients in a southern regional medical center: poor prognosis in the era of highly active antiretroviral therapy 2008
2008	Pulmonary cryptococcosis in patients without HIV infection: Factors associated with disseminated disease 2008
2008	Association of fluconazole pharmacodynamics with mortality in patients with candidemia 2008
2008	Candida infective endocarditis 2008
2008	Active surveillance to determine the impact of methicillin-resistant Staphylococcus aureus colonization on patients in intensive care units of a veterans affairs medical center 2008
2008	Prevention of Invasive Aspergillosis in High-Risk Patients: Universal Versus Preemptive, Targeted Treatment. 2008
2008	Dissemination of community-associated methicillin-resistant Staphylococcus aureus in a tertiary care hospital 2008
2007	Combination antifungal therapy for the treatment of invasive yeast and mold infections 2007
2007	Clinical practice guidelines for the management of patients with histoplasmosis: 2007 Update by the Infectious Diseases Society of America 2007
2006	Clinical research in the lay press: Irresponsible journalism raises a huge dose of doubt 2006
2006	Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia 2006
2006	Phaeoacremonium parasiticum infections confirmed by β-tubulin sequence analysis of case isolates 2006
2006	Avian influenza: what PAs need to know. 2006
2005	Antifungal combination therapy: Clinical potential 2005
2005	Initial management of candidemia at an academic medical center: Evaluation of the IDSA guidelines 2005
2004	Utility of real-time antifungal susceptibility testing for fluconazole in the treatment of candidemia 2004
2004	Emerging fungal resistance 2004
2004	Other viral bioweapons: Ebola and Marburg hemorrhagic fever 2004
2004	Surgical treatment of multiple skull abscesses associated with coccidioidomycosis 2004
2003	Epidemiology of Aspergillus terreus at a University Hospital 2003
2003	Polymicrobial septic arthritis in a patient with Wilson's disease [12] 2003
2002	Fungal brain abscess in transplant recipients: Epidemiologic, microbiologic, and clinical features 2002
2001	Invasive mold infections in allogeneic bone marrow transplant recipients 2001
2001	Implantable cardioverter-defibrillator endocarditis secondary to Candida albicans 2001
2001	Trends in frequency and susceptibilities of Candida glabrata bloodstream isolates at a University Hospital 2001
2000	Microascus cinereus (anamorph Scopulariopsis) brain abscess in a bone marrow transplant recipient 2000
2000	Fungal infections in ventricular assist devices 2000
1999	Crohn's disease presenting as septic thrombophlebitis of the portal vein (pylephlebitis): case report and review of the literature. 1999
1999	Crohn's disease presenting as septic thrombophlebitis of the portal vein (pylephlebitis): Case report and review of the literature 1999
1998	Insulinoma masquerading as factitious hypoglycemia 1998

Chapter

Year	Title	Altmetric
2018	Vaccinations in rheumatology. 411-426. 2018
2018	Systemic antifungals. 425-450. 2018
2011	Chromoblastomycosis. 427-433. 2011
2011	Cryptococcosis. 207-226. 2011
2011	Infections due to miscellaneous fungi. 455-461. 2011