Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Combining PARP and DNA-PK Inhibitors With Irradiation Inhibits HPV-Negative Head and Neck Cancer Squamous Carcinoma GrowthFrontiers in Genetics.  11. 2020
2020 The Top Concerns of Radiation Oncology Trainees in 2019: A Response from SCAROP 2020
2019 Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck CancerClinical Cancer Research.  25:7078-7088. 2019
2019 Differential escape mechanisms in cetuximab-resistant head and neck cancer cellsBiochemical and Biophysical Research Communications.  517:36-42. 2019
2019 Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapiesGenes and Diseases.  6:232-246. 2019
2019 Gender, Professional Experiences, and Personal Characteristics of Academic Radiation Oncology Chairs: Data to Inform the Pipeline for the 21st Century 2019
2019 Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastomaInternational Journal of Oncology.  54:2039-2053. 2019
2018 Bevacizumab-induced radiosenitzation in small cell lung cancerAnnals of Oncology.  29:ix148. 2018
2018 In Regard to Bossi et al 2018
2018 Qualitative Assessment of Academic Radiation Oncology Department Chairs' Insights on Diversity, Equity, and Inclusion: Progress, Challenges, and Future Aspirations 2018
2018 A Multi-institutional Comparison of SBRT and IMRT for Definitive Reirradiation of Recurrent or Second Primary Head and Neck Cancer 2018
2018 Refining Patient Selection for Reirradiation of Head and Neck Squamous Carcinoma in the IMRT Era: A Multi-institution Cohort Study by the MIRI Collaborative 2018
2018 Volume, Dose, and Fractionation Considerations for IMRT-based Reirradiation in Head and Neck Cancer: A Multi-institution Analysis 2018
2018 ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damageJournal of Biological Chemistry.  293:984-994. 2018
2017 Non-coding MIR491 is associated with less EGFr expression and greater radiosensitivity in human head and neck cancer cell linesAnnals of Oncology.  28:x6. 2017
2017 In replyJAMA Otolaryngology-Head and Neck Surgery.  143:526. 2017
2017 Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522 2017
2016 Analysis of Predictive Factors for Acute Esophagitis in Lung Cancer Radiation Therapy. 2016
2016 Analysis of Predictive Factors for Pneumonitis in Lung Cancer Radiation Therapy. 2016
2016 Association of human papillomavirus and p16 status with mucositis and dysphagia for head and neck cancer patients treated with radiotherapy with or without cetuximab: Assessment from a phase 3 registration trialEuropean journal of cancer.  64:1-11. 2016
2016 Cetuximab and radiotherapy in laryngeal preservation for cancers of the larynx and hypopharynx a secondary analysis of a randomized clinical trialJAMA Otolaryngology-Head and Neck Surgery.  142:842-849. 2016
2015 Enhancement of Cetuximab-Induced Radiosensitization by JAK-1 InhibitionBMC Cancer.  15. 2015
2015 Society of chairs of academic radiation oncology programs-endorsed radiation oncology department review process 2015
2015 Raising the next generation of physician-scientists: The chairs' perspective 2015
2015 Targeting the effector domain of the myristoylated alanine rich C-kinase substrate enhances lung cancer radiation sensitivityInternational Journal of Oncology.  46:1079-1088. 2015
2014 Pazopanib combined with radiation: In vivo model of interactionCancer Biotherapy and Radiopharmaceuticals.  29:247-250. 2014
2014 African Americans with oropharyngeal carcinoma have significantly poorer outcomes despite similar rates of human papillomavirus-mediated carcinogenesisHuman Pathology.  45:310-319. 2014
2014 Burnout in United States academic chairs of radiation oncology programs 2014
2013 Locoregional failure and the risk of distant metastasis after modern radiotherapy for head and neck cancer 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:4126. 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:64-71. 2013
2012 HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repairCancer Research.  72:4796-4806. 2012
2012 Feasibility of exercising adults with asthma: a randomized pilot study 2012
2012 MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for gliomaClinical Cancer Research.  18:3030-3041. 2012
2012 Gastrostomy tube placement and use in patients with head and neck cancer 2012
2012 Small-cell lung cancer: Prognostic factors and changing treatment over 15 yearsClinical Lung Cancer.  13:115-122. 2012
2011 Impact of average weekly dose of radiation during radiotherapy alone or chemoradiotherapy in head and neck cancer 2011
2011 Examination of laryngoesophageal dysfunction-free survival as an endpoint in nonsurgical treatment of squamous cell carcinomas of the larynx and hypopharynxCancer.  117:4447-4451. 2011
2011 Dosimetric impact of target definitions on normal structures in head and neck cancerHead and Neck Oncology.  3. 2011
2011 Diagnosis-to-treatment interval and control of locoregionally advanced head and neck cancer 2011
2011 Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors.Frontiers in Molecular Neuroscience.  4:47. 2011
2010 Comparison of Methods to Reduce Dose to Swallowing-Related Structures in Head and Neck Cancer 2010
2010 RapidArc Radiation Therapy: First Year Experience at the University of Alabama at Birmingham 2010
2010 Dosimetric Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Squamous Cell Carcinoma of the Head and Neck 2010
2010 Margin on Gross Tumor Volume and Risk of Local Recurrence in Head-and-Neck Cancer 2010
2009 Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Locally Advanced Head-and-Neck Cancer 2009
2009 EGFR FISH as a predictive factor for selection of patients with non-small cell lung cancer treated with cetuximab and chemotherapyAmerican Journal of Oncology Review.  8. 2009
2008 Locoregionally Advanced Head and Neck Cancer Treated With Primary Radiotherapy: A Comparison of the Addition of Cetuximab or Chemotherapy and the Impact of Protocol Treatment 2008
2007 A phase III study of surgical resection and paclitaxel/carboplatin chemotherapy with or without adjuvant radiation therapy for resected stage III non-small-cell lung cancer: Cancer and Leukemia Group B 9734Clinical Lung Cancer.  8:268-272. 2007
2006 Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): A meta-analysis of individual data from 1764 patientsAnnals of Oncology.  17:473-483. 2006
2006 Epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib, and concurrent 5-fluorouracil, cisplatin and radiotherapy for patients with esophageal cancer: A phase I study 2006
2005 Patterns of surgical care of lung cancer patientsAnnals of Thoracic Surgery.  80:2051-2056. 2005
2005 Results of combined-modality therapy for limited-stage small cell lung carcinoma in the elderlyCancer.  103:2349-2354. 2005
2005 Limited-stage small-cell lung cancer (stages I-III): Observations from the National Cancer Data BaseClinical Lung Cancer.  6:355-360. 2005
2004 Site-specifically traced drug release and biodistribution of a paclitaxel-antibody conjugate toward improvement of the linker structureBioconjugate Chemistry.  15:1264-1274. 2004
2004 Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer 2004
2004 Radiosensitization by Antisense Anti-MDM2 Mixed-Backbone Oligonucleotide in in Vitro and in Vivo Human Cancer ModelsClinical Cancer Research.  10:1263-1273. 2004
2004 Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells 2004
2004 Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression 2004
2003 Intraoperative radiotherapy for head and neck and skull base cancer 2003
2003 Synthesis and biological evaluation of paclitaxel-C225 conjugate as a model for targeted drug deliveryBioconjugate Chemistry.  14:302-310. 2003
2002 Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation 2002
2002 Phase III trial comparing chemotherapy plus once-daily or twice-daily radiotherapy in Stage III non-small-cell lung cancer 2002
2002 Model prediction of treatment planning for dose-fractionated radioimmunotherapy.Cancer.  94:1264-1269. 2002
2002 A quality-adjusted reanalysis of a Phase III trial comparing once-daily thoracic radiation vs. twice-daily thoracic radiation in patients with limited-stage small-cell lung cancer 2002
2002 The possible use of uniform PORT doses is important in the SEER analysis, but undetected selection bias remains an issueClinical Lung Cancer.  4:45-46. 2002
2001 Long-term results of a phase I/II study of high-dose thoracic radiotherapy with concomitant cisplatin and etoposide in limited stage small-cell lung cancer 2001
2001 Commentary "effectiveness of therapy on non-small-cell lung cancer"Clinical Lung Cancer.  2:191-192. 2001
2000 Sensitivity and action of etoposide on malignant glioma cell linesCancer Radiothérapie.  4:57-64. 2000
2000 A prospective evaluation of the timing of postoperative radiotherapy for preventing heterotopic ossification following traumatic acetabular fractures 2000
2000 A phase I study of combined UFT plus leucovorin and radiotherapy for pancreatic cancer 2000
2000 Significance of neuron-specific enolase levels before and during therapy for small cell lung cancerClinical Cancer Research.  6:597-601. 2000
1999 Factors predicting patterns of recurrence after resection of N1 non- small cell lung carcinomaAnnals of Thoracic Surgery.  68:1171-1176. 1999
1999 Frequency of noncontiguous lymph node involvement in patients with resectable nonsmall cell lung carcinomaCancer.  86:1159-1164. 1999
1999 Frequency of noncontiguous lymph node involvement in patients with resectable nonsmall cell lung carcinoma.Cancer.  86:1159-1164. 1999
1999 Patients with stage I non-small cell lung carcinoma at postoperative risk for local recurrence, distant metastasis, and death: Implications related to the design of clinical trials 1999
1999 Patterns of failure and overall survival in patients with completely resected T3 N0 M0 non-small cell lung cancer 1999
1999 The role of postoperative radiotherapy for patients with completely resected nonsmall cell lung carcinoma: Seeking to optimize local control and survival while minimizing toxicityCancer.  86:195-196. 1999
1999 The role of postoperative radiotherapy for patients with completely resected nonsmall cell lung carcinoma: seeking to optimize local control and survival while minimizing toxicity.Cancer.  86:195-196. 1999
1999 Predictors of subclinical nodal involvement in clinical stages I and II non-small cell lung cancer: Implications in the inoperable and three- dimensional dose-escalation settings 1999
1999 Combined modality therapy of A431 human epidermoid cancer using anti- EGFR antibody C225 and radiationCancer Biotherapy and Radiopharmaceuticals.  14:451-463. 1999
1999 Sensitivity and action of etoposide on malignant glioma cell linesCancer Radiothérapie.  3:57-64. 1999
1998 Ionizing radiation-induced MEK and Erk activation does not enhance survival of irradiated human squamous carcinoma cells 1998
1998 Impact of beam energy and field margin on penumbra at lung tumor-lung parenchyma interfaces 1998
1998 Adjuvant radiotherapy for squamous cell carcinoma of the tongue base: Improved local-regional disease control compared with surgery alone 1998
1998 The possible advantage of hyperfractionated thoracic radiotherapy in the treatment of locally advanced nonsmall cell lung carcinomaCancer.  82:1037-1048. 1998
1998 The possible advantage of hyperfractionated thoracic radiotherapy in the treatment of locally advanced nonsmall cell lung carcinoma: results of a North Central Cancer Treatment Group Phase III Study.Cancer.  82:1037-1048. 1998
1998 Combined neck dissection and postoperative radiation therapy in the management of the high-risk neck: A matched-pair analysis 1998
1998 Spinal cord localization in the treatment of lung cancer: Use of radiographic landmarks 1998
1997 Has radiotherapy become too expensive to be considered a treatment option for early glottic cancer? 1997
1997 Has radiotherapy become too expensive to be considered a treatment option for early glottic cancer? 1997
1997 Etoposide sensitivity of radioresistant human glioma cell linesCancer Chemotherapy and Pharmacology.  41:93-97. 1997
1997 The impact of surgical adjuvant thoracic radiation therapy for patients with nonsmall cell lung carcinoma with ipsilateral mediastinal lymph node involvementCancer.  80:1399-1408. 1997
1997 The impact of surgical adjuvant thoracic radiation therapy for patients with nonsmall cell lung carcinoma with ipsilateral mediastinal lymph node involvement.Cancer.  80:1399-1408. 1997
1997 Utility of screening procedures for detecting recurrence of disease after complete response in patients with small cell lung carcinomaCancer.  80:676-680. 1997
1997 Utility of screening procedures for detecting recurrence of disease after complete response in patients with small cell lung carcinoma.Cancer.  80:676-680. 1997
1997 Postoperative localization of porta hepatis and abdominal vasculature in pancreatic malignancies: Implications for postoperative radiotherapy planning 1997
1997 Effectiveness of postoperative irradiation in stage IIIA non-small cell lung cancer according to regression tree analyses of recurrence risksAnnals of Thoracic Surgery.  64:1402-1407. 1997
1996 The significance of the sequence of administration of topotecan and etoposideCancer Chemotherapy and Pharmacology.  39:109-112. 1996
1996 Radiation therapy for glottic cancer using 6-MV photonsCancer.  77:381-386. 1996
1996 Radiation therapy for glottic cancer using 6-MV photons.Cancer.  77:381-386. 1996
1996 Radiation therapy for glottic cancer using 6-MV photons [5]Cancer.  78:183-183a. 1996
1996 The interaction of buthionine sulphoximide (BSO) and the topoisomerase I inhibitor CPT-11British Journal of Cancer.  74. 1996
1995 Long term results of a phase I/II study of aggressive chemotherapy and sequential upper and lower hemibody radiation for patients with extensive stage small cell lung cancer.Cancer.  76:406-412. 1995
1995 Long term results of a phase I/II study of aggressive chemotherapy and sequential upper and lower hemibody radiation for patients with extensive stage small cell lung cancerCancer.  76:406-412. 1995
1995 Management of stage ie primary gastric lymphomaActa Haematologica.  94:59-68. 1995
1995 Prophylactic cranial irradiation in limited‐stage small cell lung cancerCancer.  75:1302-1309. 1995
1994 Apoptosis occurs in lymphoma cells but not in hepatoma cells following ionizing radiation and photodynamic therapyDigestive Diseases and Sciences.  39:2467-2475. 1994
1994 The interaction of epidermal growth factor and radiation in human head and neck squamous cell carcinoma cell lines with vastly different radiosensitivities 1994
1994 Topoisomerase II-independent doxorubicin-induced cytotoxicity in an extremely doxorubicin-resistant cell lineBiochemical and Biophysical Research Communications.  198:582-589. 1994
1994 Treatment of stage ie primary lymphoma of bone 1994
1994 Etoposide-resistance in the multidrug-resistant LZ-8 cells 1994
1993 Malignant tracheoesophageal fistula in patients with esophageal cancerCancer.  72:1513-1521. 1993
1992 Interaction of buthionine sulfoximine and the stabilization of DNA-topoisomerase II complexes by doxorubicin 1992
1990 Doxorubicin decreases the repair of radiation-induced DNA damageInternational Journal of Radiation Biology.  57:55-64. 1990
1989 Protection of doxorubicin cytotoxicity by cycloheximide 1989
1988 The management of vaginal melanomaCancer.  62:2066-2072. 1988

Chapter

Year Title Altmetric
2015 Interaction of Chemotherapy and Radiation.  63-79.e4. 2015
2015 Nasopharyngeal Carcinoma.  629-648.e4. 2015
2012 Interaction of Chemotherapy and Radiation.  65-82. 2012
2012 Nasopharyngeal Carcinoma.  619-638. 2012
2006 Molecular Targets for Radiosensitization.  391-414. 2006

Full Name

  • James Bonner