Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling After Myocardial Infarction..  Circulation.  143:1317-1330. 2021
2020 The BDNF rs6265 polymorphism is a modifier of cardiomyocyte contractility and dilated cardiomyopathy.  International Journal of Molecular Sciences.  21:1-16. 2020
2020 Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: Emphasis on ponatinib.  International Journal of Cardiology.  316:214-221. 2020
2020 Mouse Models of Heart Failure with Preserved or Reduced Ejection Fraction.  American Journal of Pathology.  190:1596-1608. 2020
2020 A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation..  Journal of Clinical Medicine.  9. 2020
2020 Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity.  Cells.  9. 2020
2020 Neutrophil-derived S100A8/A9 amplify granulopoiesis after myocardial infarction.  Circulation.  1080-1094. 2020
2019 Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling.  Circulation.  140:1820-1833. 2019
2019 Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction.  JCI insight.  4. 2019
2019 Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload.  Journal of Molecular and Cellular Cardiology.  130:65-75. 2019
2019 Ponatinib-induced cardiotoxicity: Delineating the signalling mechanisms and potential rescue strategies.  Cardiovascular Research.  115:966-977. 2019
2019 Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis.  JACC: Basic to Translational Science.  4:41-53. 2019
2019 Generation of Nppa-tagBFP reporter knock-in mouse line for studying cardiac chamber specification 2019
2019 IL-10–producing B cells are enriched in murine pericardial adipose tissues and ameliorate the outcome of acute myocardial infarction 2019
2019 Inhibition of GSK-3 to induce cardiomyocyte proliferation: a recipe for in situ cardiac regeneration.  Cardiovascular Research.  115:20-30. 2019
2018 Cardiomyocyte-specific deletion of GSK-3β leads to cardiac dysfunction in a diet induced obesity model.  International Journal of Cardiology.  259:145-152. 2018
2017 Chronic Neuregulin-1β Treatment Mitigates the Progression of Postmyocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus by Suppressing Myocardial Apoptosis, Fibrosis, and Key Oxidant-Producing Enzymes.  Journal of Cardiac Failure.  23:887-899. 2017
2017 Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis.  Journal of Molecular and Cellular Cardiology.  110:109-120. 2017
2017 Mechanistic Insights of Empagliflozin-Mediated Cardiac Benefits: Nearing the Starting Line: Editorial to: “Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes” by N. Hammoudi et al..  Cardiovascular Drugs and Therapy.  31:229-232. 2017
2017 Activation of the amino acid response pathway blunts the effects of cardiac stress 2017
2016 Response by Zhou et al to Letter Regarding Article, Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy.  Circulation Research.  119:e29-e30. 2016
2016 Loss of adult cardiac myocyte GSK-3 leads to mitotic catastrophe resulting in fatal dilated cardiomyopathy.  Circulation Research.  118:1208-1222. 2016
2015 The GSK-3 family as therapeutic target for myocardial diseases.  Circulation Research.  116:138-149. 2015
2014 Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure.  Journal of the American College of Cardiology.  64:696-706. 2014
2014 Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart.  Circulation.  130:419-430. 2014
2014 Sorafenib cardiotoxicity increases mortality after myocardial infarction.  Circulation Research.  114:1700-1712. 2014
2014 Prevention of liver cancer cachexia-induced cardiac wasting and heart failure.  European Heart Journal.  35:932-941. 2014
2014 Troponin I-interacting protein kinase - A novel cardiac-specific kinase, emerging as a molecular target for the treatment of cardiac disease.  Circulation Journal.  78:1514-1519. 2014
2013 Anthrax lethal toxin induces acute diastolic dysfunction in rats through disruption of the phospholamban signaling network.  International Journal of Cardiology.  168:3884-3895. 2013
2013 Caveolin and β1-integrin coordinate angiotensinogen expression in cardiac myocytes.  International Journal of Cardiology.  168:436-445. 2013
2013 GSK-3α is a central regulator of age-related pathologies in mice.  Journal of Clinical Investigation.  123:1821-1832. 2013
2013 Cancer genetics and the cardiotoxicity of the therapeutics.  Journal of the American College of Cardiology.  61:267-274. 2013
2012 Glycogen synthase kinase-3α limits ischemic injury, cardiac rupture, post-myocardial infarction remodeling and death.  Circulation.  125:65-75. 2012
2011 Rac1 and RhoA differentially regulate angiotensinogen gene expression in stretched cardiac fibroblasts.  Cardiovascular Research.  90:88-96. 2011
2011 A novel cardioprotective p38-MAPK/mTOR pathway.  Experimental Cell Research.  317:2938-2949. 2011
2010 GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice.  Journal of Clinical Investigation.  120:2280-2291. 2010
2010 Glycogen synthase kinase-3β regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo.  Circulation Research.  106:1635-1645. 2010
2009 Anthrax toxin: Pathologic effects on the cardiovascular system.  Frontiers in Bioscience.  14:2335-2357. 2009
2009 Integrins and proximal signaling mechanisms in cardiovascular disease.  Frontiers in Bioscience.  14:2307-2334. 2009
2008 Stretch-induced regulation of angiotensinogen gene expression in cardiac myocytes and fibroblasts: Opposing roles of JNK1/2 and p38α MAP kinases.  Journal of Molecular and Cellular Cardiology.  45:770-778. 2008
2007 Stretch-induced MAP kinase activation in cardiac myocytes: Differential regulation through β1-integrin and focal adhesion kinase.  Journal of Molecular and Cellular Cardiology.  43:137-147. 2007
2007 Lethal and edema toxins of anthrax induce distinct hemodynamic dysfunction.  Frontiers in Bioscience.  12:4670-4675. 2007
2007 Integrins: Novel therapeutic targets for cardiovascular diseases.  Cardiovascular and Hematological Agents in Medicinal Chemistry.  5:109-132. 2007
2000 Stress induced phosphate solubilization in bacteria isolated from alkaline soils.  FEMS Microbiology Letters.  182:291-296. 2000

Chapter

Year Title Altmetric
2009 Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease 2009

Education And Training

  • Doctor of Philosophy in Microbiology, 2006

    • Full Name

  • Hind Lal