• I received my M.D. degree from the Federal University of Rio Grande do Sul in Brazil, followed by residency in Internal Medicine at the same institution. I moved to the United States with my husband in 1986 to become a Research Fellow at the National Institutes of Health in Bethesda, Maryland, for 2 years. We then moved to Boston, where I continued working as a fellow at Harvard Medical School. In 1993, we relocated to Birmingham, Alabama. I completed a residency in Pathology and a fellowship in Hematopathology at UAB and am Board certified in Anatomic and Clinical Pathology, with subspecialties in Hematology and Transfusion Medicine/Blood Banking. I am Professor of Pathology at UAB, serving medical director of Transfusion Services. I spent my time doing patient care, teaching, clinical research and administrative duties. In the clinical arena, I am particularly interested in improving appropriateness of utilization of blood products and laboratory tests. I thoroughly enjoy giving lectures locally and in other institutions on these topics and the role of the clinical pathologist in decreasing diagnostic error. Finally, UAB is a pioneer in Patient Blood Management through a collaboration between the Transfusion Services, clinicians and hospital administration since 2007.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2020 Damage to red blood cells during whole blood storageJournal of Trauma and Acute Care Surgery.  89:344-350. 2020
    2020 The Association Between ABO Blood Type and Mortality Among Severely Injured Trauma PatientsShock.  54:205-208. 2020
    2020 Elicitation of prior probability distributions for a proposed Bayesian randomized clinical trial of whole blood for trauma resuscitationTransfusion.  60:498-506. 2020
    2020 An Automated Method for Direct Antiglobulin Testing and the Resulting Amount of Phototherapy Used at a Large Academic Medical CenterLaboratory Medicine.  51:50-55. 2020
    2020 Exclusive use of PowerFlow ports may not be appropriate for all patientsJournal of Clinical Apheresis.  35:66-68. 2020
    2019 Longitudinal assessments of plasma ADAMTS13 biomarkers predict recurrence of immune thrombotic thrombocytopenic purpuraBlood Advances.  3:4177-4186. 2019
    2019 Anti-Rh alloimmunization after trauma resuscitationTransfusion and Apheresis Science.  58. 2019
    2019 New subcutaneous PowerFlow port results in cost and time-savings in a busy outpatient apheresis clinicJournal of Clinical Apheresis.  34:482-486. 2019
    2019 Solving the calcium gluconate shortage in real-time: Mistakes made and lessons learnedJournal of Clinical Apheresis.  34:490-494. 2019
    2019 In Reply:Cleveland Clinic Journal of Medicine.  86:368-368. 2019
    2019 Older Blood Is Associated With Increased Mortality and Adverse Events in Massively Transfused Trauma Patients: Secondary Analysis of the PROPPR TrialAnnals of Emergency Medicine.  73:650-661. 2019
    2019 Validation and cost-effectiveness of an in-house dithiothreitol (DTT)treatment protocol for daratumumab patients in a large tertiary care hospital provides gateway for implementation in smaller community hospitalsTransfusion and Apheresis Science.  58:152-155. 2019
    2019 Three neglected numbers in the CBC: The RDW, MPV, and NRBC countCleveland Clinic Journal of Medicine.  86:167-172. 2019
    2019 Fat embolism syndrome due to bone marrow necrosis in patients with hemoglobinopathies: A life-threatening complication mimicking thrombotic thrombocytopenic purpuraAmerican Journal of Hematology.  94:E64-E66. 2019
    2019 Mobilization of Hematopoietic Progenitor Cells for Autologous Transplantation Using Pegfilgrastim and Plerixafor: Efficacy and Cost ImplicationsBiology of Blood and Marrow Transplantation.  25:233-238. 2019
    2019 An inquiry into the relationship between ABO blood group and thrombotic thrombocytopenic purpura 2019
    2019 Clinical factors and biomarkers predict outcome in patients with immune-mediated thrombotic thrombocytopenic purpura 2019
    2019 Erratum: Correction: Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study (PLoS Med (2018) 15:3 (e1002522) DOI: 10.1371/journal.pmed.1002522)PLoS Medicine.  16. 2019
    2019 Revisiting fat embolism in sickle syndromes: diagnostic and emergency therapeutic measuresBritish Journal of Haematology.  186:e112-e115. 2019
    2018 Elevated Syndecan-1 after Trauma and Risk of Sepsis: A Secondary Analysis of Patients from the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) TrialJournal of The American College of Surgeons.  227:587-595. 2018
    2018 Rat poisoning: A challenging diagnosis with clinical and psychological implicationsLaboratory Medicine.  49:272-275. 2018
    2018 Platelet transfusions improve hemostasis and survival in a substudy of the prospective, randomized PROPPR trialBlood Advances.  2:1696-1704. 2018
    2018 Therapeutic plasma exchange For Hashimoto's encephalopathyJournal of Clinical Apheresis.  33:444-446. 2018
    2018 Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental studyPLoS Medicine.  15. 2018
    2018 Hospital-acquired anemia due to diagnostic and therapy-related blood loss in inpatients with myasthenia gravis receiving therapeutic plasma exchangeJournal of Clinical Apheresis.  33:14-20. 2018
    2018 Management of chronic myeloid leukemia in the setting of pregnancy: when is leukocytapheresis appropriate? A case report and review of the literatureTransfusion.  58:456-460. 2018
    2018 Vascular access for therapeutic plasma exchangeTransfusion.  58:580-589. 2018
    2018 Characterization of storage-induced red blood cell hemolysis using Raman spectroscopyLaboratory Medicine.  49:298-310. 2018
    2017 Increased troponin I is associated with fatal outcome in acquired thrombotic thrombocytopenic purpuraJournal of Clinical Apheresis.  32:311-318. 2017
    2017 Do Institution-Level Blood Utilization and Blood Management Initiatives Meaningfully Impact Transfusion Practices in Cardiac Surgery?Anesthesia and Analgesia.  125:731-733. 2017
    2017 An Unusual Presentation of Thrombotic Thrombocytopenic PurpuraAmerican Journal of Medicine.  130:e323-e326. 2017
    2017 Extracorporeal photopheresis practice patterns: An international survey by the ASFA ECP subcommitteeJournal of Clinical Apheresis.  32:215-223. 2017
    2017 Clinical Scoring Systems in Thrombotic MicroangiopathiesSeminars in Thrombosis and Hemostasis.  43:540-548. 2017
    2017 Assuring hospital supply of fresh red blood cells for critically ill patientsTransfusion.  57:1320-1321. 2017
    2017 Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort studyLancet Haematology.  4:e157-e164. 2017
    2017 Increased Plasma Levels of Human Neutrophil Peptides and Complement Activation Markers in Patients With Acquired Thrombotic Thrombocytopenic Purpura.American Journal of Clinical Pathology.  147:S154. 2017
    2017 Usage Pattern of 4-Factor Prothrombin Complex Concentrate in a Tertiary Care Center.American Journal of Clinical Pathology.  147:S179-S180. 2017
    2017 A safe and effective management strategy for BCVIJournal of Trauma and Acute Care Surgery.  82:228. 2017
    2017 Ficin-treated red cells help identify clinically significant alloantibodies masked as reactions of undetermined specificity in gel microtubesLaboratory Medicine.  48:24-28. 2017
    2017 Opportunities to enhance laboratory professionals' role on the diagnostic teamLaboratory Medicine.  48:97-103. 2017
    2017 Zika Virus and Patient Blood ManagementAnesthesia and Analgesia.  124:282-289. 2017
    2016 Establishing an institutional therapeutic apheresis registryJournal of Clinical Apheresis.  31:516-522. 2016
    2016 Inside Out: Bone Marrow Necrosis and Fat Embolism Complicating Sickle-β+ ThalassemiaAmerican Journal of Medicine.  129:e321-e324. 2016
    2016 Use of hydroxyethyl starch in leukocytapheresis procedures does not increase renal toxicityTransfusion.  56:2848-2856. 2016
    2016 Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpura 2016
    2016 Absorbance and redox based approaches for measuring free heme and free hemoglobin in biological matricesRedox Biology.  9:167-177. 2016
    2016 Cryoprecipitate AHF vs. fibrinogen concentrates for fibrinogen replacement in acquired bleeding patients – an economic evaluation 2016
    2016 Patient Blood Management as Standard of CareAnesthesia and Analgesia.  123:1051-1053. 2016
    2016 Society for the Advancement of Patient Blood Management and Anesthesia & Analgesia: A New Collaboration and Home for Blood Management ResearchAnesthesia and Analgesia.  123:816-817. 2016
    2016 The thrombotic microangiopathy Registry of North America: A United States multi-institutional TMA networkJournal of Clinical Apheresis.  31:448-453. 2016
    2016 Therapeutic plasma exchange for intractable pruritus secondary to primary sclerosing cholangitisJournal of Clinical Apheresis.  31:495-496. 2016
    2016 Fat embolism syndrome secondary to bone marrow necrosis in patients with hemoglobinopathiesSouthern Medical Journal.  109:549-553. 2016
    2016 High percentage of evanescent red cell antibodies in patients with sickle cell disease highlights need for a national antibody databaseSouthern Medical Journal.  109:588-591. 2016
    2016 Anti–Blood Group Antibodies in Intravenous Immunoglobulin May Complicate Interpretation of Antibody Titers in ABO-Incompatible TransplantationAmerican Journal of Transplantation.  16:2483-2486. 2016
    2016 Apheresis research–more abstracts should be published as full manuscripts to provide more evidence for clinical practice guidelinesJournal of Clinical Apheresis.  31:353-358. 2016
    2016 The American Society for Apheresis (ASFA) is pleased to offer a Qualification in Apheresis (QIA) in partnership with The Board of Certification (BOC) of the American Society for Clinical Pathology (ASCP) starting in January of 2016!Transfusion and Apheresis Science.  54:319-320. 2016
    2016 Modification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolismFree Radical Biology and Medicine.  91:143-153. 2016
    2016 Pathology consultation on the diagnosis and treatment of thrombotic microangiopathies (TMAs)American Journal of Clinical Pathology.  145:158-165. 2016
    2015 Predicting storage-dependent damage to red blood cells using nitrite oxidation kinetics, peroxiredoxin-2 oxidation, and hemoglobin and free heme measurementsTransfusion.  55:2967-2978. 2015
    2015 Defining the effects of storage on platelet bioenergetics: The role of increased proton leak 2015
    2015 Rhesus immune globulin dosing in the obesity epidemic eraArchives of Pathology and Laboratory Medicine.  139:1084. 2015
    2015 Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhageFree Radical Biology and Medicine.  85:207-218. 2015
    2015 Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: Experience from the Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR) trialTransfusion.  55:1331-1339. 2015
    2015 Metabolic plasticity in resting and thrombin activated plateletsPLoS ONE.  10. 2015
    2015 Peroxiredoxin-2 recycling is inhibited during erythrocyte storageAntioxidants and Redox Signaling.  22:294-307. 2015
    2015 Adverse Effects of TransfusionCancer Control : Journal of the Moffitt Cancer Center.  22:16-25. 2015
    2015 Apheresis in developing countries around the WorldJournal of Clinical Apheresis.  30:238-246. 2015
    2015 Influence of Kidney Function on Risk of Supratherapeutic International Normalized Ratio-Related Hemorrhage in Warfarin Users: A Prospective Cohort StudyAmerican Journal of Kidney Diseases.  65:701-709. 2015
    2014 Perioperative management of the patient with a coronary artery stentAnesthesiology.  121:1093-1098. 2014
    2014 Compliance rates and outcomes associated with a restrictive transfusion policy in gynecologic oncology patientsGynecologic Oncology.  132:227-230. 2014
    2014 Extracorporeal photopheresis: Technique, established and novel indicationsJournal of Clinical Apheresis.  29:228-234. 2014
    2014 Membrane attack complex generation increases as a function of time in stored bloodTransfusion Medicine.  24:114-116. 2014
    2014 Out with the bad and in with the good; Red cell exchange, white cell reduction, and platelet reductionJournal of Clinical Apheresis.  29:220-227. 2014
    2014 Perceptions about blood transfusion: A survey of surgical patients and their anesthesiologists and surgeonsAnesthesia and Analgesia.  118:1301-1308. 2014
    2014 Periprocedural management of patients on anticoagulantsClinics in Laboratory Medicine.  34:595-611. 2014
    2014 Primary care physicians and the laboratory now and the futureAmerican Journal of Clinical Pathology.  142:738-740. 2014
    2014 Single-center experience with extracorporeal photopheresis in pediatric heart transplantation 2014
    2014 Successful pulmonary thromboendarterectomy in a patient with sickle cell disease treated with a single preoperative red blood cell exchangeTransfusion.  54:1901-1902. 2014
    2014 The success of our patient blood management program depended on an institution-wide change in transfusion practicesTransfusion.  54:2617-2624. 2014
    2014 Therapeutic apheresis academy 2013: Beyond bordersJournal of Clinical Apheresis.  29:189-190. 2014
    2014 Therapeutic plasma exchange rapidly improves cardiac allograft function in patients with presumed antibody-mediated rejectionJournal of Clinical Apheresis.  29:316-321. 2014
    2014 Thrombotic thrombocytopenic purpura: 2012 American Society for Apheresis (ASFA) consensus conference on classification, diagnosis, management, and future researchJournal of Clinical Apheresis.  29:148-167. 2014
    2013 Relapses of thrombotic thrombocytopenic purpura after treatment with rituximabJournal of Clinical Apheresis.  28:390-394. 2013
    2013 The level of complement activation fragments is higher in red blood cell units than segmentsTransfusion and Apheresis Science.  49:692-693. 2013
    2013 Novel ADAMTS13 mutations in an obstetric patient with Upshaw-Schulman syndromeJournal of Clinical Apheresis.  28:311-316. 2013
    2013 Thrombotic thrombocytopenic purpura does not show seasonal variation in AlabamaTransfusion.  53:1864-1865. 2013
    2013 Acquired von Willebrand's disease in myelofibrosis and essential thrombocythemiaHaemophilia.  19. 2013
    2013 Decoding laboratory test names: A major challenge to appropriate patient careJournal of General Internal Medicine.  28:453-458. 2013
    2013 Letters to the editorTransfusion.  53:235-237. 2013
    2013 The isolated prolonged PTTAmerican Journal of Hematology.  88:82-85. 2013
    2012 Erythrocyte storage increases rates of NO and nitrite scavenging: Implications for transfusion-related toxicityBiochemical Journal.  446:499-508. 2012
    2012 How we closed the gap between red blood cell utilization and whole blood collections in our institutionTransfusion.  52:1857-1867. 2012
    2012 Platelets induce neutrophil extracellular traps in transfusion-related acute lung injuryJournal of Clinical Investigation.  122:2661-2671. 2012
    2012 Massive hemolysis due to thrombotic thrombocytopenic purpura in a patient with AIDSTransfusion.  52:1408-1409. 2012
    2012 Multiorgan failure and bone marrow necrosis in three adults with sickle cell-β +-thalassemiaAmerican Journal of Hematology.  87:621-624. 2012
    2012 Recommendations for appropriate activated partial thromboplastin time reagent selection and utilizationAmerican Journal of Clinical Pathology.  137:904-908. 2012
    2012 Pathology consultation on the laboratory evaluation of thrombophilia when, how, and whyAmerican Journal of Clinical Pathology.  137:553-560. 2012
    2012 Red blood cell transfusion: A Clinical practice guideline from the AABBAnnals of Internal Medicine.  157:49-58. 2012
    2011 Update on extracorporeal photopheresis in heart and lung transplantationJournal of Clinical Apheresis.  26:146-151. 2011
    2011 Von Willebrand disease laboratory diagnosis: The Saga continuesAmerican Journal of Clinical Pathology.  135:818-820. 2011
    2011 The clinical pathologist as consultantAmerican Journal of Clinical Pathology.  135:11-12. 2011
    2010 Duration of red cell storage influences mortality after trauma 2010
    2010 Systemic neutrophilic aggregates in transfusion-related acute lung injuryTransfusion.  50:1427-1428. 2010
    2010 Educating medical students in laboratory medicine: A proposed curriculumAmerican Journal of Clinical Pathology.  133:533-542. 2010
    2010 Platelet count and prothrombin time help distinguish thrombotic thrombocytopenic purpura-hemolytic uremic syndrome from disseminated intravascular coagulation in adultsAmerican Journal of Clinical Pathology.  133:460-465. 2010
    2010 Guidelines on the use of therapeutic apheresis in clinical practice - Evidence-based approach from the apheresis applications committee of the American Society for ApheresisJournal of Clinical Apheresis.  25:83-177. 2010
    2009 Is therapeutic plasma exchange indicated for patients with gemcitabine-induced hemolytic uremic syndrome?Journal of Clinical Apheresis.  24:209-214. 2009
    2009 Transfusion and pneumonia in the trauma intensive care unit: An examination of the temporal relationship 2009
    2009 A simple tool to educate laboratory staff about anticoagulationLaboratory Medicine.  40:687-690. 2009
    2009 Blood utilization at a level I trauma center: Is this as good as it gets?American Surgeon.  75:693-697. 2009
    2009 Transfusion and pneumonia in the trauma intensive care unit: an examination of the temporal relationship. 2009
    2009 Thrombotic Thrombocytopenic Purpura and Heparin-Induced Thrombocytopenia: Two Unique Causes of Life-Threatening ThrombocytopeniaClinics in Laboratory Medicine.  29:321-338. 2009
    2009 An adolescent with a history of menorrhagiaLaboratory Medicine.  40:271-273. 2009
    2009 An inquiry into the relationship between ABO blood group and thrombotic thrombocytopenic purpura 2009
    2009 Free flap failure secondary to dual thrombophiliaMicrosurgery.  29:62-65. 2009
    2009 Genetic susceptibility to VTE: a primary care approach.Journal of the American Academy of Physician Assistants.  22:20-25. 2009
    2008 Transfusions in the less severely injured: Does age of transfused blood affect outcomes? 2008
    2008 Transfusions in the less severely injured: does age of transfused blood affect outcomes? 2008
    2008 Age of transfused blood: An independent predictor of mortality despite universal leukoreduction 2008
    2008 A new "initial" case of transfusion-related acute lung injuryBlood.  111:5257-5258. 2008
    2008 Screening with the activated protein C resistance assay yields significant savings in a patient population with low prevalence of factor V LeidenAmerican Journal of Clinical Pathology.  129:494-499. 2008
    2008 Transfusion-related acute lung injury: Past, present, and futureAmerican Journal of Clinical Pathology.  129:287-297. 2008
    2007 Continuous infusion of calcium gluconate in 5% albumin is safe and prevents most hypocalcemic reactions during therapeutic plasma exchangeJournal of Clinical Apheresis.  22:265-269. 2007
    2007 Category IV indications for therapeutic apheresis - ASFA fourth special issueJournal of Clinical Apheresis.  22:176-180. 2007
    2007 Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Apheresis Applications Committee of the American Society for ApheresisJournal of Clinical Apheresis.  22:106-175. 2007
    2007 Teaching Medical Students Basic Principles of Laboratory MedicineClinics in Laboratory Medicine.  27:411-424. 2007
    2007 Refractory thrombocytopenia and positive platelet crossmatches without HLA or platelet-specific antibodiesAmerican Journal of Hematology.  82:175-176. 2007
    2007 Predictors of response and relapse in a cohort of adults with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: A single-institution experienceTransfusion.  47:107-114. 2007
    2007 Thrombelastographic measures of clot propagation: A comparison of alpha with the maximum rate of thrombus generation 2007
    2006 Estimating blood needs for very-low-birth-weight infantsTransfusion.  46:1915-1920. 2006
    2006 Autoimmune hemolytic anemia in an infant with giant cell hepatitis.American Journal of Hematology.  81:199-201. 2006
    2006 Rejection with hemodynamic compromise: Objective evidence for efficacy of photopheresis 2006
    2006 A neonate with bleeding and multiple factor deficienciesLaboratory Medicine.  37:95-97. 2006
    2006 Bilateral pulmonary thromboembolism in a 42-year-old womanLaboratory Medicine.  37:229-231. 2006
    2006 Evaluation of thrombocytopeniaLaboratory Medicine.  37:248-250. 2006
    2006 Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatinAmerican Journal of Hematology.  81:199-201. 2006
    2006 Laboratory evaluation and transfusion support of patients with autoimmune hemolytic anemia.American Journal of Clinical Pathology.  125 Suppl. 2006
    2006 Photopheresis in solid organ transplant rejection.Journal of Clinical Apheresis.  21:72-77. 2006
    2005 Current diagnosis and management of Thrombotic Thrombocytopenic Purpura: Utility of von-Willebrand Factor cleaving protease (ADAMTS 13)Blood Transfusion.  3:32-41. 2005
    2005 Acute transient leukopenia as a sign of TRALI [5]American Journal of Hematology.  80:90-91. 2005
    2005 Unusual thromboses associated with protein S deficiency in patients with acquired immunodeficiency syndrome: Case reports and review of the literatureAIDS Research and Human Retroviruses.  21:753-756. 2005
    2005 A 34-year-old-male with progressive neurologic declineLaboratory Medicine.  36:764-766. 2005
    2005 Thrombosis risk testing in the clinical laboratoryLaboratory Medicine.  36:115-118. 2005
    2005 Transfusion safety: what has been done; what is still needed? 2005
    2004 Point-of-care testing in oral anticoagulation: what is the point? 2004
    2004 Hemolytic uremic syndrome revisited: Shiga toxin, factor H, and fibrin generation.American Journal of Clinical Pathology.  121 Suppl. 2004
    2004 Thrombotic thrombocytopenic purpura: from platelet aggregates to plasma.American Journal of Clinical Pathology.  121 Suppl. 2004
    2003 Etiology of Pulmonary Thromboembolism in the Absence of Commonly Recognized Risk FactorsAmerican Journal of Forensic Medicine and Pathology.  24:329-333. 2003
    2003 Phase II study of docetaxel plus enoxaparin in chemotherapy-naive patients with metastatic non-small cell lung cancer: Preliminary resultsLung Cancer.  42:237-245. 2003
    2003 Scurvy: An often forgotten cause of bleeding [2]American Journal of Hematology.  74:85-87. 2003
    2003 Laboratory evaluation of coagulation inhibitorsLaboratory Medicine.  34:584-588. 2003
    2003 Treatment of single factor deficiencies: a case study approach.Clinical Laboratory Science.  16:120-122. 2003
    2003 Clinical Pathology Consultation Improves Coagulation Factor Utilization in Hospitalized AdultsAmerican Journal of Clinical Pathology.  120:938-943. 2003
    2003 The effect of lupus anticoagulant in the second-generation assay for activated protein C resistanceAmerican Journal of Clinical Pathology.  119:66-71. 2003
    2003 Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura. 2003
    2002 Altering interface detector positioning in combination with prestorage filtration to achieve a better quality of single donor platelet concentrates using the CS 3000 Plus blood separatorJournal of Clinical Apheresis.  17:21-26. 2002
    2002 Management of a patient with HIV infection-induced anemia and thrombocytopenia who presented with thrombotic thrombocytopenic purpuraAmerican Journal of Hematology.  69:228-231. 2002
    2002 Characteristics of photopheresis treatments for the management of rejection in heart and lung transplant recipients.Journal of Clinical Apheresis.  17:27-32. 2002
    2002 Testing for genetic predisposition to venous thrombosis. 2002
    2001 Patients with thrombotic thrombocytopenic purpura commonly develop metabolic alkalosis during therapeutic plasma exchangeJournal of Clinical Apheresis.  16:120-124. 2001
    2001 When to suspect hypercoagulability and how to investigate itAnnals of Diagnostic Pathology.  5:177-183. 2001
    2000 Defining/Measuring the Value of Clinical Information 2000
    2000 A pregnant patient with sickle cell disease and cefotetan-induced immune hemolysisLaboratory Medicine.  31:541-543. 2000
    2000 Histologic examination of bone marrow core biopsy specimens has limited value in the diagnosis of mycobacterial and fungal infections in patients with the acquired immunodeficiency syndromeAnnals of Diagnostic Pathology.  4:1-6. 2000
    1998 The yield of bone marrow biopsy and culture compared with blood culture in the evaluation of HIV-infected patients for mycobacterial and fungal infectionsAmerican Journal of Medicine.  104:123-128. 1998
    1998 Bone marrow biopsy and blood culture in evaluating HIV patients [5] (multiple letters)American Journal of Medicine.  105:457-458. 1998
    1998 Two acute pediatric abdominal catastrophes from strangulated left paraduodenal herniasPediatric Emergency Care.  14:347-349. 1998
    1997 Comparative in vitro antimicrobial susceptibilities of nosocomial isolates of Acinetobacter baumannii and synergistic activities of nine antimicrobial combinationsAntimicrobial Agents and Chemotherapy.  41:881-885. 1997
    1997 Detection of Kingella kingae bacteremia and identification of the organism in the clinical laboratory: Experience from two casesClinical Microbiology Newsletter.  19:73-76. 1997
    1997 Genotypic investigation of multidrug-resistant Acinetobacter baumannii infections in a medical intensive care unitJournal of Hospital Infection.  37:125-135. 1997
    1996 Hyaluronate capsule and surface M protein in resistance to opsonization of group A streptococciInfection and Immunity.  64:1495-1501. 1996
    1994 Functional activity of antibodies to the group B polysaccharide of group B streptococci elicited by a polysaccharide-protein conjugate vaccineInfection and Immunity.  62:1593-1599. 1994
    1992 Growth in acidic media increases production of phosphatidylinositol-specific phospholipase C by Staphylococcus aureus 1992
    1992 Prevention of C3 deposition by capsular polysaccharide is a virulence mechanism of type III group B streptococciInfection and Immunity.  60:3986-3993. 1992
    1989 High-dose intravenous immunoglobulin modifies complement-mediated in vivo clearanceBlood.  74:326-333. 1989
    1989 Phosphatidylinositol-specific phospholipase C, a possible virulence factor of Staphylococcus aureusJournal of Clinical Microbiology.  27:2451-2454. 1989


    Year Title Altmetric
    2018 Blood management 2018
    2015 A Quick Guide to Hemostasis (former Coagulation Testing) – third edition 2015
    2009 A Quick Guide to Coagulation Testing – second edition 2009
    2006 A Quick Guide to Coagulation Testing 2006
    2006 A Quick Guide to Transfusion Medicine 2006


    Year Title Altmetric
    2018 Therapeutic apheresis for hematologic emergencies.  341-361. 2018
    2018 Understanding Advanced Hematologic Testing.  41-63. 2018
    2017 Hemostasis and thrombosis-laboratory diagnosis and treatment.  295-325. 2017
    2017 Patient blood management.  201-218. 2017
    2010 Apheresis in Solid Organ Transplantation 2010
    2007 Hemorrhagic Coagulation Disorders 2007

    Research Overview

  • Patient Blood Management - I am interested in various aspects of clinical research in the fields of coagulation and transfusion medicine. Since UAB is a center of reference for apheresis, we receive patients from throughout Alabama and neighboring states to be treated here for thrombotic thrombocytopenic purpura (TTP). In the last several years, I have been involved in several projects about TTP as seen in my list of publications. Other areas of interest in Transfusion Medicine include the effect of storage time on the red blood cells and the repercussion for the patients, as well as transfusion-related acute lung injury (TRALI). In the area of coagulation, I have an interest in hypercoagulability, heparin-induced thrombocytopenia diagnosis, and cost-effective utilization of laboratory assays.

    Keywords - Thrombotic thrombocytopenic purpura (TTP), patient blood management
  • Principal Investigator On

  • Private Grant  awarded by JUNO THERAPEUTICS 2019 - 2024
  • Private Grant  awarded by JUNO THERAPEUTICS 2020 - 2023
  • Private Grant  awarded by JUNO THERAPEUTICS 2020 - 2023
  • Education And Training

  • Doctor of Medicine, Federal University of Rio Grande do Sul 1983
  • UAB Hospital, Residency 1997
  • Federal University of Rio Grande do Sul (UFRGS), Residency 1985
  • UAB Hospital, Postdoctoral Fellowship 1998
  • Awards And Honors

  • Dean’s Excellence Award in Teaching, Senior Faculty, 2018
  • Argus Society Award – Best Lecturer Nominee – Hematopathology, Class of 2019, 2017
  • Award for Outstanding Contributions to Management Sciences and Patient Safety, 2017
  • Excellence in Mentorship Award, 2017
  • Presidential Award, 2017
  • UAB Medicine's Best Doctors in America, 2017
  • Inaugural Executive Section Editor of Anesthesia&Analgesia new section “Blood Management”, 2016
  • UAB Medicine's Best Doctors in America, 2016
  • Klaus Mayer Lecture in Laboratory Medicine, 2015
  • UAB Medicine's Best Doctors in America, 2015
  • Alpha Omega Alpha Honor Medical Society, 2014
  • Argus Society Award – Best Lecturer Nominee – Hematopathology, Class of 2016, 2014
  • UAB Medicine's Best Doctors in America, 2014
  • Argus Society Award – Best Lecturer Nominee – Hematopathology, Class of 2015, 2013
  • UAB Medicine's Best Doctors in America, 2013
  • First Place, Innovation Award, Blood Management Program, 2012
  • UAB Medicine's Best Doctors in America, 2012
  • Becky Trigg Outstanding Woman Faculty Member, 2011
  • UAB Medicine's Best Doctors in America, 2011
  • Top-rated Hospital Medical Director (perfect score), 2010
  • Shu T. Huang Award for Excellence in Laboratory Medicine Education, 2010
  • Argus Society Award – Best Lecturer Runner-Up – Hematopathology, Class of 2012, 2010
  • UAB Medicine's Best Doctors in America, 2010
  • UAB Medicine's Best Doctors in America, 2009
  • Shu T. Huang Award for Excellence in Laboratory Medicine Education, 2009
  • Argus Society Award – Best Lecturer Runner-Up – Hematopathology, Class of 2011, 2009
  • Argus Society Award – Best Lecturer – Hematopathology, Class of 2010, 2009
  • Lecturer Award – ASFA Annual Meeting, 2008
  • Argus Society Award – Best Lecturer – Hematopathology, Class of 2009, 2008
  • Argus Society Award nominee, 2006
  • Excellence in Resident Education in Clinical Pathology Award, 2005
  • Award of Excellence for “Care”, 2003
  • Best Teacher Award from Hematology/Oncology fellows to non-Hematology faculty, 2002
  • Excellence in Resident Education in Clinical Pathology Award, 2002
  • Excellence in Resident Education in Clinical Pathology Award, 2001
  • Paul E. Strandjord Young Investigator Award, 1996
  • Chief Resident in Laboratory Medicine, 1995
  • Visiting Fellow, 1986
  • Full Name

  • Marisa Marques