Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Technical advance: The use of tree shrews as a model of pulmonary fibrosisPLoS ONE.  15. 2020
2020 Mitochondrial quality control in pulmonary fibrosisRedox Biology.  33. 2020
2020 C(C)Learing the role of chemokines in pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  62:546-547. 2020
2019 Effect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation (PrePARE): a randomised controlled trial 2019
2019 Increased flux through the mevalonate pathway mediates fibrotic repair without injuryJournal of Clinical Investigation.  129:4962-4978. 2019
2019 NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosisJCI insight.  4. 2019
2016 Cu,Zn-superoxide dismutase-mediated redox regulation of Jumonji domain containing 3 modulates macrophage polarization and pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  55:58-71. 2016
2015 Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structureThe FASEB Journal.  29:3527-3536. 2015
2014 3 Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophagesJournal of Biological Chemistry.  289:33391-33403. 2014
2013 Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophagesJournal of Biological Chemistry.  288:20745-20757. 2013
2012 Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosisJournal of Biological Chemistry.  287:3301-3312. 2012
2011 Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generationJournal of Biological Chemistry.  286:15597-15607. 2011
2010 Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1Journal of Biological Chemistry.  285:25062-25073. 2010

Education And Training

  • Doctor of Philosophy Level Degree in Radiation Biology / Radiobiology, University of Iowa 2014
  • Doctor of Medicine, 2009
  • Full Name

  • Chao He