• Deep brain stimulation (DBS) is more effective than medications and other conventional therapies for motor symptoms of Parkinson's disease, dystonia, and essential tremor. Emerging DBS technologies such as directional and closed loop stimulation have substantial potential to improve a variety of patient outcomes. However these devices are increasingly adaptable and complex, and we lack robust tools to fully realize their therapeutic potential. Dr. Walker's lab investigates how deep brain stimulation works using a multimodal approach that integrates electroencephalography, electrocorticography, single unit recordings, neuroimaging, and behavioral assessment in patients with movement disorders. Our goal is to obtain new knowledge about the therapeutic mechanism of DBS and apply these findings to guide technological innovation, both for established indications and for emerging indications in neurology and psychiatry.

    Originally from Starkville, Mississippi, Dr. Walker graduated Phi Beta Kappa and Summa Cum Laude from Birmingham-Southern College in 1997 with a BA in music. He attended medical school at the University of Alabama at Birmingham, where he participated in the Howard Hughes Medical Institute Research Scholars Program at the National Institutes of Health in Bethesda, Maryland. Following medical school, Dr. Walker pursued his neurology residency and movement disorders fellowship training at the University of Alabama at Birmingham.
  • Investigator On

  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2018 - 2022
  • University of Alabama at Birmingham_The Edumond J. Safra Fellowship in Movement Disorders 2017  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2017 - 2020
  • UAB Bachmann-Straus Dystonia and Parkinson's Disease Center of Excellence  awarded by Bachmann-Strauss Dystonia & Parkinson Foundation, Inc 2013 - 2018
  • Post-Stroke Aphasia and rTMS Treatment (PART) Study  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2012 - 2018
  • The Effect of Low Frequency STN DBS on Sleep and Vigilance in PD Patients  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2012 - 2017
  • Private Grant  awarded by SANGAMO BIOSCIENCES, INC. 2013 - 2016
  • Alzheimer's Disease Cooperative Study  awarded by University of California, San Diego 2013 - 2015
  • UAB PD Neuroprotection Clinical Trial Center  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2014
  • A Double-Blind, Placebo-Controlled (Sham Surgery), Randomized, Multicenter Study Evaluating CERE-110 Gene Delivery in Subjects with Mild to Moderate Alzheimer's Disease (CERE 110-3)  awarded by University of California, San Diego 2011 - 2013
  • Stenting vs. Aggressive Medical Management for Preventing Recurrent Events in Intracranial Stenosis (SAMMPRIS)  awarded by Medical University of South Carolina 2008 - 2013
  • UAB Parkinson's Disease Neuroprotection Clinical Trial Center  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2008 - 2012
  • Education And Training

  • Doctor of Medicine, University of Alabama at Birmingham 2001
  • Bachelor of Humanities in Music, Birmingham-Southern College 1997
  • Baptist Medical Center - Montclair, Internship 2002
  • UAB Hospital Neurology, Residency 2006
  • Full Name

  • Harrison Walker