Selected Publications

Academic Article

Year Title Altmetric
2019 Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical TrialCirculation Research.  125:957-968. 2019
2019 Temperature-Responsive Polymersomes of Poly(3-methyl- N-vinylcaprolactam)- block-poly(N-vinylpyrrolidone) to Decrease Doxorubicin-Induced CardiotoxicityBiomacromolecules.  20:3989-4000. 2019
2019 Gravin gravitates atherogenesis to atheroprogression in the obesogenic settingAJP - Heart and Circulatory Physiology.  317:H790-H792. 2019
2019 Inhibition of FPR2 impaired leukocytes recruitment and elicited non-resolving inflammation in acute heart failurePharmacological Research.  146. 2019
2019 Lipoxygenase drives lipidomic and metabolic reprogramming in ischemic heart failureMetabolism.  96:22-32. 2019
2019 Obesogenic diet in aging mice disrupts gut microbe composition and alters neutrophil:lymphocyte ratio, leading to inflamed milieu in acute heart failureFederation proceedings.  33:6456-6469. 2019
2019 Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironmentJournal of Cellular Physiology.  234:3910-3920. 2019
2019 Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in miceRedox Biology.  21. 2019
2019 Pretreatment of carprofen impaired initiation of inflammatory- and overlapping resolution response and promoted cardiorenal syndrome in heart failureLife Sciences.  218:224-232. 2019
2019 Re-evaluating the causes and consequences of non-resolving inflammation in chronic cardiovascular diseaseHeart Failure Reviews2019
2019 Role of neutrophils in ischemic heart failurePharmacology and Therapeutics2019
2019 Specialized Pro-resolving Mediators Directs Cardiac Healing and Repair with Activation of Inflammation and Resolution Program in Heart FailureAdvances in Experimental Medicine and Biology.  1161:45-64. 2019
2018 Subacute treatment of carprofen facilitate splenocardiac resolution deficit in cardiac injuryJournal of Leukocyte Biology.  104:1173-1186. 2018
2018 The failing of the obesity paradox in the failing heartAJP - Heart and Circulatory Physiology.  315:H1353-H1355. 2018
2018 Cancer Therapy-Induced Cardiovascular Toxicity: Doxorubicin triggers splenic contraction and irreversible dysregulation of cox and lox that alters the inflammation-resolution program in the myocardiumAJP - Heart and Circulatory Physiology.  315:H1091-H1100. 2018
2018 Unified nexus of macrophages and maresins in cardiac reparative mechanismsFederation proceedings.  32:5227-5237. 2018
2018 The mouse heart attack research tool 1.0 databaseAJP - Heart and Circulatory Physiology.  315:H522-H530. 2018
2018 Immune responsive resolvin D1 programs myocardial infarction–induced cardiorenal syndrome in heart failureFederation proceedings.  32:3717-3729. 2018
2018 Paradigm shift – Metabolic transformation of docosahexaenoic and eicosapentaenoic acids to bioactives exemplify the promise of fatty acid drug discoveryBiotechnology Advances.  36:935-953. 2018
2018 Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarctionJournal of Molecular and Cellular Cardiology.  118:70-80. 2018
2018 Splenic leukocytes define the resolution of inflammation in heart failureScience Signaling.  11. 2018
2018 Comprehensive targeted and non-targeted lipidomics analyses in failing and non-failing heartFresenius' Journal of Analytical Chemistry.  410:1965-1976. 2018
2018 Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammationAJP - Heart and Circulatory Physiology.  314:H160-H169. 2018
2018 Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathologyAJP - Heart and Circulatory Physiology.  314:H255-H267. 2018
2018 Nox2 activity is required in obesity-mediated alteration of bone remodelingOxidative Medicine and Cellular Longevity.  2018. 2018
2017 Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stressesAJP - Heart and Circulatory Physiology.  313:H1098-H1108. 2017
2017 Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction HealingScientific Reports.  7. 2017
2017 Obesity and Cardiometabolic Defects in Heart Failure Pathology.Comprehensive Physiology.  7:1463-1477. 2017
2017 Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healingAJP - Heart and Circulatory Physiology.  313:H89-H102. 2017
2017 Metabolic and Biochemical Stressors in Diabetic Cardiomyopathy.Frontiers in Cardiovascular Medicine.  4:31. 2017
2016 Neutrophils: Friend, foe, or contextual ally in myocardial healingJournal of Molecular and Cellular Cardiology.  97:44-46. 2016
2016 Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stressJournal of Translational Medicine.  14. 2016
2016 Myocardial infarction superimposed on aging: MMP-9 deletion promotes M2 macrophage polarizationJournals of Gerontology, Series A.  71:475-483. 2016
2016 CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal during Cardiac RemodelingCirculation: Cardiovascular Genetics.  9:14-25. 2016
2016 Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarctionAging.  8:2611-2634. 2016
2015 Big eater macrophages dominate inflammation resolution following myocardial infarctionJournal of Molecular and Cellular Cardiology.  87:225-227. 2015
2015 Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarctionJournal of Molecular and Cellular Cardiology.  85:229-239. 2015
2015 Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular functionJournal of Molecular and Cellular Cardiology.  84:24-35. 2015
2015 Nox2 mediates skeletal muscle insulin resistance induced by a high fat dietJournal of Biological Chemistry.  290:13427-13439. 2015
2015 Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammationAJP - Heart and Circulatory Physiology.  309:H1827-H1836. 2015
2015 Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarctionAJP - Heart and Circulatory Physiology.  308:H269-H280. 2015
2014 Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricleAntioxidants and Redox Signaling.  21:1974-1985. 2014
2014 Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarctionJournal of Molecular and Cellular Cardiology.  76:84-93. 2014
2014 Aging and energetics' 'Top 40' future research opportunities 2010-2013F1000Research.  3. 2014
2014 Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomicsPROTEOMICS - Clinical Applications.  8:595-602. 2014
2014 Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarctionBasic Research in Cardiology.  109. 2014
2014 Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac FunctionPLoS Pathogens.  10. 2014
2013 Reduced BDNF attenuates inflammation and angiogenesis to improve survival and cardiac function following myocardial infarction in miceAJP - Heart and Circulatory Physiology.  305. 2013
2013 Matrix metalloproteinase (MMP)-9: A proximal biomarker for cardiac remodeling and a distal biomarker for inflammationPharmacology and Therapeutics.  139:32-40. 2013
2013 Texas 3-Step decellularization protocol: Looking at the cardiac extracellular matrixJournal of Biochemical and Biophysical Methods.  86:43-52. 2013
2013 Concentrated fish oil (Lovaza®) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 miceProceedings of the Society for Experimental Biology and Medicine.  238:610-622. 2013
2013 Matrix metalloproteinase-28 deletion exacerbates cardiac dysfunction and rupture after myocardial infarction in mice by inhibiting M2 macrophage activationCirculation Research.  112:675-688. 2013
2013 Cardiac wound healing post-myocardial infarction: A novel method to target extracellular matrix remodeling in the left ventricleMethods in Molecular Biology.  1037:313-324. 2013
2013 Cardiac wound healing post-myocardial infarction: A novel method to target extracellular matrix remodeling in the left ventricleMethods in Molecular Biology.  1037:313-324. 2013
2013 Obese and diabetic KKAy mice show increased mortality but improved cardiac function following myocardial infarctionCardiovascular Pathology.  22:481-487. 2013
2012 Extracellular matrix and fibroblast communication following myocardial infarctionJournal of Cardiovascular Translational Research.  5:848-857. 2012
2012 Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarctionJournal of Molecular and Cellular Cardiology.  53:599-608. 2012
2012 DHA derivatives of fish oil as dietary supplements: A nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicityExpert Opinion on Drug Discovery.  7:711-721. 2012
2012 Mathematical modeling and stability analysis of macrophage activation in left ventricular remodeling post-myocardial infarction.BMC Genomics.  13 Suppl 6. 2012
2012 Roles of saturated vs. polyunsaturated fat in heart failure survival: Not all fats are created equalCardiovascular Research.  93:4-5. 2012
2011 t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposityJournal of Cellular Physiology.  226:2406-2414. 2011
2011 Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J miceJournal of Nutritional Biochemistry.  22:459-469. 2011
2011 Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging micePharmacological Research.  63:300-307. 2011
2011 Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in miceExperimental Gerontology.  46:43-52. 2011
2010 High fat diet-induced animal model of age-associated obesity and osteoporosisJournal of Nutritional Biochemistry.  21:1162-1169. 2010
2010 Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone miceJournal of Immunology.  184:5280-5286. 2010
2010 Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J miceJournal of Nutritional Biochemistry.  21:332-337. 2010
2009 The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPA Rγ and SIRT-1 expression on a calorie restricted dietOxidative Medicine and Cellular Longevity.  2:307-316. 2009
2009 Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle lossBiochemical and Biophysical Research Communications.  383:513-518. 2009
2009 Effect of CLA isomers and their mixture on aging C57Bl/6J miceZeitschrift Ewrnahrungswissenschaft.  48:409-418. 2009
2006 Hypoglycemic activity of Cassia auriculata in neonatal streptozotocin-induced non-insulin dependent diabetes mellitus in ratsJournal of Natural Remedies.  6:14-18. 2006


Year Title Altmetric
2013 Extracellular matrix biomarkers of adverse remodeling after myocardial infarction.  383-412. 2013

Education And Training

  • Doctor of Philosophy in Pharmacology, University of Mumbai 2007
  • Full Name

  • Ganesh Halade