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Gu Jing
Instructor
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gujing@uab.edu
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Gu Jing
Instructor
Positions
Scientist (C)
,
Comprehensive Diabetes Center
,
School of Medicine
Instructor (P)
,
Medicine - Endocrinology, Diabetes, and Metabolism
,
Department of Medicine
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2021
Human Glucagon Expression Is under the Control of miR-320a
.
Endocrinology
. 162.
2021
2021
Human Glucagon Expression Is under the Control of miR-320a.
.
Endocrinology
. 162.
2021
2020
Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action
.
Cell Metabolism
. 32:353-365.e8.
2020
2016
Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop
.
Molecular Metabolism
. 5:1208-1215.
2016
2016
MiR-204 targets PERK and regulates UPR signaling and β-cell apoptosis
.
Molecular Endocrinology
. 30:917-924.
2016
2014
MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell
.
Journal of Biological Chemistry
. 289:36275-36283.
2014
2014
Characterization of calmodulin-fas death domain interaction: An integrated experimental and computational study
.
Biochemistry
. 53:2680-2688.
2014
2014
Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2
.
Journal of Biological Chemistry
. 289:11807-11815.
2014
2014
Thioredoxin-interacting protein stimulates its own expression via a positive feedback loop
.
Molecular Endocrinology
. 28:674-680.
2014
2013
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
.
Nature Medicine
. 19:1141-1146.
2013
2013
FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells
.
Journal of Biological Chemistry
. 288:23194-23202.
2013
2012
Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes
.
Molecular Pharmacology
. 82:541-549.
2012
2012
Preventing β-cell loss and diabetes with calcium channel blockers
.
Diabetes
. 61:848-856.
2012
2012
Reduced CaM/FLIP binding by a single point mutation in c-FLIP
L
modulates Fas-mediated apoptosis and decreases tumorigenesis
.
Laboratory Investigation
. 92:82-90.
2012
2011
Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-Extracellular Signal-regulated Kinase (ERK)
.
Journal of Biological Chemistry
. 286:24776-24784.
2011
2011
Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis
.
Laboratory Investigation
. 91:896-904.
2011
2009
Cloning and characterization of Prisilkin-39, a novel matrix protein serving a dual role in the prismatic layer formation from the oyster Pinctada fucata
.
Journal of Biological Chemistry
. 284:10841-10854.
2009
2007
N40, a novel nonacidic matrix protein from pearl oyster nacre, facilities nucleation of aragonite in vitro
.
Biomacromolecules
. 8:3597-3601.
2007
2007
Immunolocalization of an acid phosphatase from pearl oyster (Pinctada fucata) and its in vitro effects on calcium carbonate crystal formation
.
Marine Biotechnology: an international journal focusing on marine genomics, molecular biology and biotechnology
. 9:650-659.
2007
2007
Different effects of Pb
2+
and Cu
2+
on immune and antioxidant enzyme activities in the mantle of Pinctada fucata
.
Environmental Toxicology and Pharmacology
. 24:122-128.
2007
2006
Metal accumulation and enzyme activities in gills and digestive gland of pearl oyster (Pinctada fucata) exposed to copper
.
Comparative Biochemistry and Physiology C: Toxicology and Pharmacology
. 144:184-190.
2006
2006
Purification and partial characterization of two acid phosphatase forms from pearl oyster (Pinctada fucata)
.
Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology
. 143:229-235.
2006
Research
Investigator On
Promote Beta-Cell Survival by Blocking TXNIP: Role of Calcium Channel Blocker
awarded by
Juvenile Diabetes Research Foundation International
TXNIP Regulation of Endogenous Beta Cell Mass
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Targeting TXNIP to Enhance Beta Cell Mass in T1D
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Background
Education And Training
Doctor of Social or Behavioral Sciences in Biology / Biological Sciences,
Tsinghua University
2007
Contact
Full Name
Gu
Jing