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Jennifer Guimbellot
Associate Professor
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guim@uab.edu
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Jennifer Guimbellot
Associate Professor
Positions
Scientist (C)
,
Cystic Fibrosis Research Center
,
School of Medicine
Associate Professor (P)
,
Pediatric - Pulmonary & Sleep Medicine
,
Pediatrics
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2022
Ivacaftor-elexacaftor-tezacaftor and tacrolimus combination in cystic fibrosis
.
Journal of Cystic Fibrosis
. 21:e8-e10.
2022
2022
Use of elexacaftor/tezacaftor/ivacaftor among cystic fibrosis lung transplant recipients
.
Journal of Cystic Fibrosis
.
2022
2021
CFTR function and clinical response to modulators parallel nasal epithelial organoid swelling
2021
2021
Combination CFTR modulator therapy in children and adults with cystic fibrosis
2021
2021
Long term clinical effectiveness of ivacaftor in people with the G551D CFTR mutation
.
Journal of Cystic Fibrosis
. 20:213-219.
2021
2020
Highlights from the 2019 North American Cystic Fibrosis Conference
.
Pediatric Pulmonology
. 55:2225-2232.
2020
2020
Variable cellular ivacaftor concentrations in people with cystic fibrosis on modulator therapy
.
Journal of Cystic Fibrosis
. 19:742-745.
2020
2020
Human nasal epithelial organoids for therapeutic development in cystic fibrosis
.
Genes
. 11:1-17.
2020
2020
Females with cystic fibrosis demonstrate a differential response profile to ivacaftor compared with males
.
American Journal of Respiratory and Critical Care Medicine
. 201:996-998.
2020
2019
Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging
.
Biomedical Optics Express
. 10:5414-5430.
2019
2019
Effectiveness of ivacaftor in cystic fibrosis patients with non-G551D gating mutations
.
Journal of Cystic Fibrosis
. 18:102-109.
2019
2018
Tracheostomy in children: Epidemiology and clinical outcomes
.
Pediatric Pulmonology
. 53:1269-1275.
2018
2018
Potential pathogenicity of Inquilinus limosus in a pediatric patient with cystic fibrosis
.
Pediatric Pulmonology
. 53:E21-E23.
2018
2018
Sensitivity of ivacaftor to drug-drug interactions with rifampin, a cytochrome P450 3A4 inducer
.
Pediatric pulmonology. Supplement
. 53:E6-E8.
2018
2017
Nasospheroids permit measurements of CFTR-dependent fluid transport
.
JCI Insight
. 2.
2017
2017
Toward inclusive therapy with CFTR modulators: Progress and challenges
.
Pediatric pulmonology. Supplement
. 52:S4-S14.
2017
2009
Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
.
BMC Medical Genomics
. 2.
2009
2008
Role of oxygen availability in CFTR expression and function
.
American Journal of Respiratory Cell and Molecular Biology
. 39:514-521.
2008
2004
Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines
.
Journal of Biological Chemistry
. 279:22578-22584.
2004
2003
EWS/FLI function varies in different cellular backgrounds
.
Experimental Cell Research
. 290:414-419.
2003
2001
Peptides, made to order
.
Scientist (Philadelphia, Pa.)
. 15:25-26.
2001
2001
Tailored arrays
.
Scientist (Philadelphia, Pa.)
. 15:26-28.
2001
Research
Principal Investigator On
(KBoost) Pharmacometric Approaches to Precision Optimization of Ivacaftor Response
awarded by
Cystic Fibrosis Foundation ^
Characterizing CFTR Modulated Changes in Sweat Chloride - Pharmacokinetics
awarded by
Cystic Fibrosis Foundation ^
Cytochrome p450 Enzymes In Metabolism And Efficacy Of Ivacaftor
awarded by
Cystic Fibrosis Foundation ^
Development of Personalized Approaches to CFTR Modulator Efficacy
awarded by
KAUL PEDIATRIC RESEARCH INSTITUTE
Elexacaftor/Tezacaftor/Ivacaftor after Lung Transplant
awarded by
UNIVERSITY OF WASHINGTON
First/Second Year Clinical Fellowship
awarded by
Cystic Fibrosis Foundation ^
Novel Approaches to CFTR Modulator Mechanism in Cystic Fibrosis
awarded by
Cystic Fibrosis Foundation ^
Pharmacometric Approaches to Precision Optimization of Ivacaftor Response in Cystic Fibrosis Patients
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
StatNet-University of Alabama at Birmingham
awarded by
Cystic Fibrosis Foundation ^
Investigator On
Making iPSCs a Reliable Model for Cystic Fibrosis Research
awarded by
Cystic Fibrosis Foundation ^
Private Grant
awarded by
CFD RESEARCH CORPORATION
Success with Therapies Research Consortium: UAB Site
awarded by
Cystic Fibrosis Foundation ^
Success with Therapies Research Consortium: UAB Site
awarded by
Cystic Fibrosis Foundation ^
UAB CF Research and Translation Core Center
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
UAB Research and Development Program
awarded by
Cystic Fibrosis Foundation ^
miR-145 Target Site Blockade is a Selective Strategy to Enhance CFTR Restoration and Readthrough
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Background
Education And Training
Columbia University Medical Center, Internship
Columbia University Medical Center, Residency
University of North Carolina at Chapel Hill, Postdoctoral Fellowship
Doctor of Medicine,
University of Alabama at Birmingham
2008
Awards And Honors
American Thoracic Society, Assembly on Pediatrics Abstract Scholarship
,
2014
Johnny Carson Award/Evening of Scholarship for Best Overall Research
,
2013
Outstanding Graduate Student (Doctoral)
,
2007
Outstanding Graduate Student (Doctoral)
,
2006
European Respiratory Society 4th Lung Scient Conference Travel Award
,
2006
American Society of Human Genetics Annual Meeting Travel Award
,
2006
Genetics Award, National Student Research Forum
,
2005
Barry M. Goldwater Scholar
,
1999
Contact
Full Name
Jennifer
Guimbellot