Positions

Overview

  • Dr. Siegal was born in New York where he attended college. He received his medical degree from the University of Louisville and his PhD from the University of Minnesota. He was a Resident and Research Fellow at the Mayo Graduate School of Medicine and completed both a post-doctoral fellowship at the National Cancer Institute, NIH and a surgical pathology fellowship at the University of Minnesota. Prior to coming to UAB in 1990, he was a tenured faculty member at the University of North Carolina at Chapel Hill. Dr. Siegal has been married for over 40 years and has 2 adult daughters and 4 grandchildren.
  • Research Overview

  • Dr. Siegal is an extramurally funded experimental and diagnostic pathologist whose research interest for more than 3 decades has been focused in Cancer Biology. Specifically, he has been interested in studying tumor-matrix interactions during angiogenesis, tumor invasion and metastasis in breast cancer. Previous efforts by his group have been directed towards developing new reliable in vitro model systems for studying the effect of nutritional and other factors on prostate and breast cancer progression in humans. He has participated in multiple gene therapy studies utilizing a variety of distinct strategies including mutation compensation, genetic immunopotentiation, and molecular chemotherapy to treat solid human neoplasms, principally ovarian carcinoma. He was most recently funded to develop a conditionally replicating canine adenovirus model that could be used to study host-vector interactions for more effective antitumor oncolytic effect. Dr. Siegal also directs the Histomorphometry & Molecular Analysis Core of the UAB Core Center for Musculoskeletal Disorders. Dr. Siegal's clinical research interests have focused on studies of bone tumors and related conditions. He is the Editor-in-Chief of Laboratory Investigation and serves on the editorial board of an additional twenty journals.
  • Education And Training

  • Doctor of Philosophy in Pathology Residency Program, University of Minnesota System : Twin Cities 1979
  • Doctor of Medicine, University of Louisville 1974
  • Mayo Graduate School of Medicine, Internship 1975
  • Mayo Graduate School of Medicine, Residency 1979
  • Mayo Graduate School of Medicine, Residency 1978
  • Mayo Graduate School of Medicine, Residency 1976
  • ALABAMA MEDICAL LICENSURE COMMISSION, Postdoctoral Fellowship 1982
  • Warren G. Magnuson Clinical Center, Postdoctoral Fellowship 1981
  • Mayo Graduate School of Medicine, Postdoctoral Fellowship 1977
  • Awards And Honors

  • 3rd Jishuitan Pathology Forum Lecturer – Bone & Soft Tissue Tumours, 2018
  • C.A.P. Lifetime Achievement Award, 2017
  • Albert Nelson Marquis Lifetime Achievement Award, 2017
  • Vernie A. Stembridge Lecturer – 95th Ann. Meeting, Texas Soc. Of Pathologists, 2016
  • A.S.I.P. Robbins Distinguished Educator Award, 2015
  • Miembro Honorario, Asociacion Venezolana para el Estudio de Tumors Musculo-Esqueleticos (AVETME), 2013
  • Emma Sadler Moss Lecturer - Louisiana State University (LSU), 2012
  • The Griffin Society [UAB Scientific Society], 2009
  • Arthur Purdy Stout Lecturer - A.S.C.P. Annual Meeting, 2009
  • Citation Classic (Ref #18) Barsky S. et al. Lab Invest 49:140, 1983, 2003
  • Milton S. Hales Lecturer - West Virginia University, 2003
  • 1st Carter/Makley Lecturer -Case Western Reserve Univ., Institute of Pathology, 2003
  • 3rd Walter R. Benson Lecturer -University of North Carolina, 2003
  • Farrell Prize, International Skeletal Society [Shared with M.J. Pitt], 2001
  • Alpha Omega Alpha, the Medical Honor Society, 1996
  • International Skeletal Society, 1994
  • Phi Beta Delta, Honor Society for International Scholars, 1993
  • Fellow of the Royal Society of Medicine, London, 1992
  • Order of the Grail - Valkyries (UNC Honorary), 1990
  • Order of the Grail - Valkyries (UNC Honorary), 1990
  • Jefferson-Pilot Fellow in Academic Medicine, 1986
  • International Business Machines Corporation Junior Faculty Development Awardee, 1985
  • Junior Faculty Fellow of the American Cancer Society, 1983
  • Clinical Fellow of the American Cancer Society, 1981
  • Sigma Xi, The Scientific Research Society of North America, 1976
  • Omicron Delta Kappa, the National Leadership Honor Society, 1974
  • Who's Who Among Students in American Colleges & Universities, 1969
  • Beta Beta Beta, The National Biology Honor Society, 1968
  • Alpha Epsilon Delta, the International Premedical Honor Society, 1966
  • Full Name

  • Gene Siegal