• Dr. Gabrielle Rocque is an Assistant Professor of Medicine in the Divisions of Hematology & Oncology and Gerontology, Geriatrics, & Palliative Care at the University of Alabama at Birmingham (UAB). She completed her undergraduate degree, medical doctorate, Internal Medicine residency, and fellowship in Hematology & Oncology at the University of Wisconsin- Madison. She also completed a Masters of Science in Public Health from UAB. She currently practices as a medical oncologist, specializing in the care of women with breast cancer.

    Dr. Rocque’s research interests include improving the quality of healthcare delivery for cancer patients with an emphasis on shared decision-making, payment reform, and provision of supportive care services to patients. She served as Medical Director a successful 2012 Center for Medicare and Medicaid Innovation Award, which focused on improving health and healthcare costs by implementing a lay navigator workforce to support cancer patients across from diagnosis through survivorship and end-of-life. She also received an American Cancer Society Mentored Research Scholar Grant to develop treatment plans aimed to enhance shared decision making for patients with metastatic breast cancer. She is active within UAB’s payment reform initiatives, and serves as the co-Director of UAB’s Oncology Care Model Steering Committee.

    Dr. Rocque has a strong interest in the interface between community oncology practices and academia. She is a former chair of the American Society of Clinical Oncology (ASCO) Measures Task Force and the ASCO Quality of Care Committee.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2020 Urban vs. rural residence and outcomes in older breast cancer patients. 2020
    2020 Clinical Cancer Advances 2020: Annual report on progress against cancer from the American Society of Clinical oncology 2020
    2020 Integrating geriatric assessment into routine gastrointestinal (GI) consultation: The Cancer and Aging Resilience Evaluation (CARE) 2020
    2020 Patient-reported outcomes in the Translational Breast Cancer Research Consortium 2020
    2020 Study protocol for a multisite randomised controlled trial of a rehabilitation intervention to reduce participation restrictions among female breast cancer survivors 2020
    2019 The project ENABLE Cornerstone randomized pilot trial: Protocol for lay navigator-led early palliative care for African-American and rural advanced cancer family caregivers 2019
    2019 Healthy lifestyle discussions between healthcare providers and older cancer survivors: Data from 12 cancer centers in the Southeastern United States 2019
    2019 Hypofractionated radiation in older women with breast cancer 2019
    2019 Patient Navigation in Cancer: The Business Case to Support Clinical Needs 2019
    2019 What Is Important When Making Treatment Decisions in Metastatic Breast Cancer? A Qualitative Analysis of Decision-Making in Patients and Oncologists 2019
    2019 An examination of the relationship between patient satisfaction with healthcare and quality of life in a geriatric population with cancer in the Southeastern United States 2019
    2019 Lay navigation across the cancer continuum for older cancer survivors: Equally beneficial for Black and White survivors? 2019
    2019 Impact of travel time on health care costs and resource use by phase of care for older patients with cancer 2019
    2019 Disparities in Hospice Utilization for Older Cancer Patients Living in the Deep South 2019
    2019 Evaluating the impact of treatment care planning on quality measures 2019
    2019 How family caregivers of persons with advanced cancer assist with upstream healthcare decision-making: A qualitative study 2019
    2019 Unmet social support needs among older adults with cancer 2019
    2019 Bridging the data-free zone: Decision making for older adults with cancer 2019
    2019 Engaging multidisciplinary stakeholders to drive shared decision-making in oncology 2019
    2019 Guideline discordance and patient cost responsibility in medicarebeneficiaries with metastatic breast cancer 2019
    2019 Impact of Guideline-Discordant Treatment on Cost and Health Care Utilization in Older Adults with Early-Stage Breast Cancer 2019
    2019 Quality Improvement at the Health System Level: Measurement, Risk Stratification, Disparity Populations, and Governance. 2019
    2019 Trust but Verify: Exploring the Role of Treatment-Related Information and Patient-Physician Trust in Shared Decision Making Among Patients with Metastatic Breast Cancer 2019
    2019 Visualization of sequential treatments in metastatic breast cancer 2019
    2018 Factors Associated with Family Caregivers' Confidence in Future Surrogate Decision Making for Persons with Cancer 2018
    2018 Concordance with NCCN treatment guidelines: Relations with health care utilization, cost, and mortality in breast cancer patients with secondary metastasis 2018
    2018 Choosing Wisely at the End of Life: Use of Shorter Courses of Palliative Radiation Therapy for Bone Metastasis 2018
    2018 First report of real-world patient characteristics and treatment patterns from POLARIS: Palbociclib in hormone receptor-positive (HR+) advanced breast cancer: A prospective, multicenter, noninterventional study 2018
    2018 Impact of nonconcordance with NCCN guidelines on resource utilization, cost, and mortality in de novo metastatic breast cancer 2018
    2018 Hospice care, cancer-directed therapy, and Medicare expenditures among older patients dying with malignant brain tumors 2018
    2018 Adapting an Early Palliative Care Intervention to Family Caregivers of Persons With Advanced Cancer in the Rural Deep South: A Qualitative Formative Evaluation 2018
    2018 Possible underestimation of the provision of palliative care 2018
    2018 Where are the opportunities for reducing health care spending within alternative payment models? 2018
    2018 Improving shared decision-making in chronic lymphocytic leukemia through multidisciplinary education 2018
    2018 Participation and interest in support services among family caregivers of older adults with cancer 2018
    2018 Most impactful factors on the health-related quality of life of a geriatric population with cancer 2018
    2018 Radiation therapy utilization in Medicare beneficiaries with early-stage breast cancer 2018
    2018 What is the role of symptom management and patient-reported outcomes in adherence to aromatase inhibitors? 2018
    2018 Healthcare utilization, Medicare spending, and sources of patient distress identified during implementation of a lay navigation program for older patients with breast cancer 2018
    2018 Lay patient navigators’ perspectives of barriers, facilitators and training needs in initiating advance care planning conversations with older patients with cancer 2018
    2017 Choosing wisely in oncology: Are we ready for value-based care? 2017
    2017 Hospital-based end-of-life care and costs for older patients with malignant brain tumors 2017
    2017 The self-care practices of family caregivers of persons with poor prognosis cancer: differences by varying levels of caregiver well-being and preparedness 2017
    2017 Feasibility of a Telehealth Educational Program on Self-Management of Pain and Fatigue in Adult Cancer Patients 2017
    2017 Resource use and medicare costs during lay navigation for geriatric patients with cancer 2017
    2017 Implementation and Impact of Patient Lay Navigator-Led Advance Care Planning Conversations 2017
    2017 Establishing a core set of performance measures to improve value in cancer care: ASCO consensus conference recommendation report 2017
    2017 Choosing wisely: Opportunities for improving value in cancer care delivery? 2017
    2016 Patient-centered support in the survivorship care transition: Outcomes from the Patient-Owned Survivorship Care Plan Intervention 2016
    2016 Adherence to the Choosing Wisely Campaign Recommendations for Radiation Treatment Duration in Breast Cancer: Analysis of Medicare Data at 12 Centers in the Southeastern United States. 2016
    2016 Intensity Modulated Radiation Therapy in Breast Cancer: Analysis of Medicare Data at 12 Institutions. 2016
    2016 Treatment summaries and follow-up care instructions for cancer survivors: Improving survivor self-efficacy and health care utilization 2016
    2016 The patient care connect program: Transforming health care through lay navigation 2016
    2016 Guiding lay navigation in geriatric patients with cancer using a distress assessment tool 2016
    2016 Integrating palliative care into the oncology clinic: A joint management approach 2016
    2015 A Quantitative Study of Triggered Palliative Care Consultation for Hospitalized Patients with Advanced Cancer the results of Cohorts 1 and 2 were presented at the 2014 Annual Assembly of the American Academy of Hospice and Palliative Medicine (AAHPM) and the Hospice and Palliative Nurses Association (HPNA). 2015
    2014 Guiding lay navigation using the distress thermometer. 2014
    2014 Update on adjuvant chemotherapy for early breast cancer 2014
    2014 Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles 2014
    2014 Development and evaluation of a survey to assess survivor knowledge change after survivorship care plans: WiSDOM-B (Wisconsin survey of cancer DiagnOsis and management in breast cancer) 2014
    2013 Reply to A. Azad et al 2013
    2013 Palliative care reduces morbidity and mortality in cancer 2013
    2013 Inpatient hospitalization of oncology patients: Are we missing an opportunity for end-of-life care? 2013
    2012 Adjuvant therapy for HER2+ breast cancer: Practice, perception, and toxicity 2012
    2011 MiRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy 2011
    2011 The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation 2011

    Research Overview

  • Shared decision making, value, Metastatic breast cancer, Supportive care, Payment reform
  • Principal Investigator On

  • TBCRC-AURORA US: A Prospective Biospecimen Repository in Metastic Breast Cancer  awarded by Johns Hopkins University 2020 - 2025
  • Evaluating Shared Decision Making in Cancer  awarded by CANCERCARE 2019 - 2024
  • Private Grant  awarded by F.Hoffmann-La Roche Ltd. 2019 - 2023
  • Enhancing Shared Decision Making in Metastatic Breast Cancer  awarded by American Cancer Society, Inc. 2017 - 2022
  • Safety Net Program Survey: Launched 07/05/2017  awarded by PATIENT ADVOCATE FOUNDATION 2019 - 2021
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2017 - 2021
  • Evaluating Adoption and Outcomes of Early Stage Breast Cancer Clinical Trials Results in Underrepresented and Unrepresented Populations  awarded by Johnson (Robert Wood) Foundation 2019 - 2021
  • Private Grant  awarded by Genentech 2019 - 2020
  • Private Grant  awarded by Genentech 2017 - 2019
  • Private Grant  awarded by CAREVIVE SYSTEMS, INC. 2018 - 2019
  • TBCRC 029_Clinical and Biological Characterization of Male Breast Cancer  awarded by Johns Hopkins University 2015 - 2019
  • Outliers - Extreme Long-term Survivors with Metastatic Breast Cancer  awarded by University of Wisconsin-Madison 2018
  • Impact Of Guideline Concordant Treatment On Cost And Health Care Utilization In Early Stage Breast Cancer Patients  awarded by UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER (SAN ANTONIO) 2017 - 2018
  • Private Grant  awarded by Genentech 2016 - 2018
  • Private Grant  awarded by CAREVIVE SYSTEMS, INC. 2015 - 2016
  • Private Grant  awarded by PACKHEALTH 2014 - 2016
  • Investigator On

  • SWOG Purchase Services Agreement  awarded by Oregon Health & Science University 2020 - 2025
  • TBCRC 050 UAB 17112-A Phase 1b/2 Study of the PARP Inhibitor Niraparib in Combination with Trastuzumab in Patients with Metastatic HER2+ Breast Cancer  awarded by Johns Hopkins University 2019 - 2024
  • A Randomized, Phase II Study Comparing Trastuzumab and Vinorelbine in Combination with Avelumab or Avelumab and Utomilumab (41BB/CD137 Agonist), In Patients with Her2-Positive Metastatic Breast Cancer who have Progressed on Prior Trastuzumab and Pertuzumab: The "AVIATOR” Study  awarded by Johns Hopkins University 2019 - 2024
  • TBCRC 049 UAB 1794: A Phase II Non-randomized Study to Assess the Safety and Efficacy of the Combination of Tucatinib and Trastuzumab and Capecitabine for Treatment of Leptomeningeal Metastases in HER2 Positive Breast Cancer  awarded by Johns Hopkins University 2018 - 2023
  • TBCRC 048 UAB 1846: A Phase 2 Study of Olaparib Monotherapy in Metastatic Breast Cancer Patients with Germline or Somatic Mutations in DNA Repair Genes  awarded by Johns Hopkins University 2018 - 2023
  • UAB17127:A phase Ib trial of fulvestrant, palbociclib (CDK4/6 inhibitor) and erdafitinib (JNJ- 42756493, pan-FGFR tyrosine kinase inhibitor) in ER+/HER2–/FGFR-amplified metastatic breast cancer (MBC)  awarded by VANDERBILT UNIVERSITY 2018 - 2023
  • Private Grant  awarded by SEATTLE GENETICS, INC. 2018 - 2023
  • Private Grant  awarded by ZYMEWORKS BIOPHARMACEUTICALS 2019 - 2023
  • Private Grant  awarded by TESARO, INC. 2018 - 2021
  • Harvest for Health in Older Cancer Survivors  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2016 - 2021
  • Private Grant  awarded by F.Hoffmann-La Roche Ltd. 2018 - 2021
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2018 - 2021
  • Private Grant  awarded by EMD SERONO 2016 - 2021
  • Private Grant  awarded by F.Hoffmann-La Roche Ltd. 2019 - 2021
  • UAB 1643- A Randomized Phase II Trial of Fulvestrant With or Without Ribociclib After Progression on Aromatase Inhibition Plus Cyclin-Dependent Kinase 4/6 Inhibition in Patients with Unresectable or Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer  awarded by Columbia University 2016 - 2020
  • Private Grant  awarded by SEATTLE GENETICS, INC. 2018 - 2020
  • UAB 1764:The Targeted Agent and Profiling Utilization Registry (TAPUR) Study  awarded by American Society of Clinical Oncology 2017 - 2020
  • Enabling A Paradigm Shift: A Preference-Tolerant RCT of Personalized vs Annual Screening of Breast Cancer (WISDOM)  awarded by QUANTUM LEAP HEALTH CARE 2018 - 2020
  • UAB 1761: A Randomized, Placebo-Controlled, Double-Blind, Phase II trial of Nanoparticle Albumin-Bound Paclilaxel (Nab-Paclilaxel, Abraxane®) with or without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple Negative Breast Cancer.  awarded by University of Chicago 2017 - 2020
  • Alliance for Clinical Trials in Oncology Payment Agreement  awarded by MAYO CLINIC 2017 - 2020
  • Private Grant  awarded by SEATTLE GENETICS, INC. 2014 - 2020
  • Quantifying the Burden of Breast Cancer Decision Making in Older Women  awarded by American Society of Clinical Oncology 2019 - 2020
  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group 2014 - 2020
  • Southwest Oncology Group Purchase Service Agreement  awarded by Oregon Health & Science University 2015 - 2020
  • TBCRC030 - A Randomized Phase II Study of Preoperative Cisplatin versus Paclitaxel in Patients with Triple Negative Breast Cancer: Evaluating the Homologous Recombination Deficiency (HRD) Biomarker  awarded by Johns Hopkins University 2014 - 2019
  • Private Grant  awarded by SYNDAX PHARMACEUTICALS 2018 - 2019
  • CITY Health II - The Center for the Study of Community Health  awarded by National Center for Chronic Disease Prevention & Health Promo./CDC/DHHS 2014 - 2019
  • TBCRC 037 UAB 1644:A Trial of Endocrine Response In Women with Invasive Lobular Breast Cancer.  awarded by University of Pittsburgh 2016 - 2019
  • UAB 1326: A Phase II Study of Neratinib Alone and in Combination with Fulvestrant in Metastatic HER2 Non-Amplified but HER2 Mutant Breast Cancer  awarded by Washington University 2013 - 2019
  • Private Grant  awarded by Genentech 2018 - 2019
  • Private Grant  awarded by Genentech 2018 - 2019
  • Private Grant  awarded by ZYMEWORKS BIOPHARMACEUTICALS 2018 - 2019
  • Utilizing Multiomic Advanced Diagnostics to Identify Palbociclib Response Predictors and a Post-treatment Multiomic Signature for Patients with ER+/HER2- Metastatic Breast Cancer  awarded by THE SIDE-OUT FOUNDATION 2017 - 2019
  • Private Grant  awarded by CAREVIVE SYSTEMS, INC. 2017 - 2019
  • Private Grant  awarded by INNOCRIN PHARMACEUTICALS, INC. 2016 - 2019
  • UAB NRG Oncology Member Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2015 - 2019
  • Private Grant  awarded by F.Hoffmann-La Roche Ltd. 2016 - 2019
  • Private Grant  awarded by PHARMACYCLICS, INC. 2015 - 2018
  • Private Grant  awarded by SEATTLE GENETICS, INC. 2013 - 2018
  • Private Grant  awarded by SYNDAX PHARMACEUTICALS 2016 - 2018
  • Private Grant  awarded by TESARO, INC. 2016 - 2018
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2014 - 2018
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2016 - 2018
  • Private Grant  awarded by CELLDEX THERAPEUTICS, INC. 2014 - 2018
  • Private Grant  awarded by F.Hoffmann-La Roche Ltd. 2016 - 2018
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2016 - 2018
  • Private Grant  awarded by Novartis Pharma AG 2014 - 2017
  • Private Grant  awarded by INCYTE CORPORATION 2014 - 2016
  • Private Grant  awarded by ONCOTHYREON, INC. 2015 - 2016
  • Private Grant  awarded by ARQULE 2014 - 2016
  • Health Care Innovation Challenge  awarded by Centers for Medicare and Medicaid Services/DHHS 2012 - 2015
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2015
  • Education And Training

  • Doctor of Medicine, University of Wisconsin System : Madison 2007
  • University of Wisconsin Hospital & Clinics, Residency 2010
  • University of Wisconsin Hospital & Clinics, Postdoctoral Fellowship 2013
  • Full Name

  • Gabrielle Rocque