Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Insurance status and head and neck radiotherapy interruption disparities in the Mid-Southern United States 2020
2020 Location as Destiny: Identifying Geospatial Disparities in Radiation Treatment Interruption by Neighborhood, Race, and Insurance 2020
2020 Head and Neck Cancers, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology 2020
2020 Reduced Margin Stereotactic Body Radiation Therapy for Early Stage Non-Small Cell Lung Cancers.Cureus.  12:e8618. 2020
2020 Lipid microsphere bound oxycodone for pain management in patients receiving radiotherapy for head and neck cancerSupportive Care in Cancer2020
2019 Repeat gamma knife stereotactic radiosurgery in the treatment of trigeminal neuralgia: A single-center experience and focused review of the literatureJournal of Clinical Neuroscience.  70:102-107. 2019
2019 Changing functional status within 6 months posttreatment is prognostic of overall survival in patients with head and neck cancer: NRG Oncology Study 2019
2019 Electromagnetic Transponder Based Tracking and Gating in the Radiotherapeutic Treatment of Thoracic MalignanciesPractical Radiation Oncology.  9:456-464. 2019
2019 Head and neck cancer survivors' preferences for and evaluations of a post-treatment dietary interventionNutrition Journal.  18. 2019
2019 Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trialsCancer.  125:2027-2038. 2019
2019 Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE): A Next-Generation Sequencing StudyHead and Neck Pathology.  13:162-168. 2019
2019 Feasibility Outcomes of a Pilot Randomized Clinical Trial to Increase Cruciferous and Green Leafy Vegetable Intake in Posttreatment Head and Neck Cancer SurvivorsJournal of the Academy of Nutrition and Dietetics.  119:659-671. 2019
2019 Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial 2019
2019 Longitudinal assessment of anchored transponder migration following lung stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  20:17-22. 2019
2018 First-line treatment of widely metastatic BRAF-mutated salivary duct carcinoma with combined BRAF and MEK inhibition 2018
2018 Higher carbohydrate intake is associated with increased risk of all-cause and disease-specific mortality in head and neck cancer patients: results from a prospective cohort studyInternational Journal of Cancer.  143:1105-1113. 2018
2018 Head and neck cancers: Advantages of advanced radiation therapy and importance of supportive care 2018
2018 NCCN guidelines ® insights: Head and neck cancers, version 1.2018 featured updates to the NCCN guidelines 2018
2017 NCCN Guidelines Insights: Head and Neck Cancers, Version 2.2017 2017
2017 In replyJAMA Otolaryngology-Head and Neck Surgery.  143:526. 2017
2016 Long-term results of a phase I/II trial of the addition of celecoxib to chemoradiotherapy for locally advanced or recurrent squamous cell carcinoma of the head-and-neckJournal of Radiation Oncology.  5:363-369. 2016
2016 Establishing quality indicators for neck dissection: Correlating the number of lymph nodes with oncologic outcomes (NRG Oncology RTOG 9501 and RTOG 0234)Cancer.  122:3464-3471. 2016
2016 Smoking cessation, version 1.2016 clinical practice guidelines in oncology 2016
2016 Analysis of Predictive Factors for Acute Esophagitis in Lung Cancer Radiation Therapy. 2016
2016 Analysis of Predictive Factors for Pneumonitis in Lung Cancer Radiation Therapy. 2016
2016 Association of human papillomavirus and p16 status with mucositis and dysphagia for head and neck cancer patients treated with radiotherapy with or without cetuximab: Assessment from a phase 3 registration trialEuropean journal of cancer.  64:1-11. 2016
2016 Cetuximab and radiotherapy in laryngeal preservation for cancers of the larynx and hypopharynx a secondary analysis of a randomized clinical trialJAMA Otolaryngology-Head and Neck Surgery.  142:842-849. 2016
2016 Correlation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience 2016
2016 A phase 2 study of radiosurgery and temozolomide for patients with 1 to 4 brain metastasesAdvances in Radiation Oncology.  1:83-88. 2016
2015 Head and neck cancers, version 1.2015 featured updates to the NCCN guidelines 2015
2015 Evaluation of 3M™ molecular detection assay (MDA) Listeria for the detection of Listeria species in selected foods and environmental surfaces: Collaborative study, first action 2014.06Journal of AOAC INTERNATIONAL.  98:993-1002. 2015
2015 Evaluation of 3M™ molecular detection assay (MDA) Listeria monocytogenes for the detection of Listeria monocytogenes in selected foods and environmental surfaces: Collaborative study, first action 2014.07Journal of AOAC INTERNATIONAL.  98:980-992. 2015
2014 Head and neck cancers, version 2.2014 2014
2014 Induction cetuximab, paclitaxel, and carboplatin followed by chemoradiation with cetuximab, paclitaxel, and carboplatin for stage III/IV head and neck squamous cancer: a phase II ECOG-ACRIN trial (E2303)Annals of Oncology.  25:2036-2041. 2014
2014 Pazopanib combined with radiation: In vivo model of interactionCancer Biotherapy and Radiopharmaceuticals.  29:247-250. 2014
2014 Final results of local-regional control and late toxicity of rtog 9003: A randomized trial of altered fractionation radiation for locally advanced head and neck cancer 2014
2014 African Americans with oropharyngeal carcinoma have significantly poorer outcomes despite similar rates of human papillomavirus-mediated carcinogenesisHuman Pathology.  45:310-319. 2014
2014 A technique using 99mTc-mebrofenin SPECT for radiotherapy treatment planning for liver cancers or metastasesMedical Dosimetry.  39:7-11. 2014
2014 Comparison of plan quality and delivery time between volumetric arc therapy (rapidarc) and gamma knife radiosurgery for multiple cranial metastasesNeurosurgery.  75:409-417. 2014
2013 Stereotactic body radiation therapy (SBRT) for lung malignancies: Preliminary toxicity results using a flattening filter-free linear accelerator operating at 2400 monitor units per minuteRadiation Oncology.  8. 2013
2013 Head and Neck Cancers, version 2.2013 2013
2013 Phase 1 study of erlotinib plus radiation therapy in patients with advanced cutaneous squamous cell carcinoma 2013
2013 Intraoperative ultrasound guidance during intracavitary brachytherapy applicator placement in cervical cancer; The university of alabama at birmingham experienceInternational Journal of Gynecological Cancer.  23:559-566. 2013
2013 Locoregional failure and the risk of distant metastasis after modern radiotherapy for head and neck cancer 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:4126. 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:64-71. 2013
2012 Prognostic significance of thyroid or cricoid cartilage invasion in laryngeal or hypopharyngeal cancer treated with organ preserving strategiesRadiation Oncology.  7. 2012
2012 Influenza immunization in older adults with and without cancerJournal of the American Geriatrics Society.  60:2099-2103. 2012
2012 Plan quality and treatment planning technique for single isocenter cranial radiosurgery with volumetric modulated arc therapyPractical Radiation Oncology.  2:306-313. 2012
2012 Tobacco smoking and increased risk of death and progression for patients with p16-positive and p16-negative oropharyngeal cancerJournal of Clinical Oncology.  30:2102-2111. 2012
2012 Mucosal melanoma of the head and neck 2012
2012 Mucosal melanoma: A clinically and biologically unique disease entity 2012
2012 SU‐E‐T‐434: Use of Deformable Registration for Cumulated Dose Calculation in Image‐Guided Intracavitary Bracytherapy for Cervical CancerMedical Physics.  39:3804. 2012
2011 Impact of average weekly dose of radiation during radiotherapy alone or chemoradiotherapy in head and neck cancer 2011
2011 Examination of laryngoesophageal dysfunction-free survival as an endpoint in nonsurgical treatment of squamous cell carcinomas of the larynx and hypopharynxCancer.  117:4447-4451. 2011
2011 Integrating epidermal growth factor receptor assay with clinical parameters improves risk classification for relapse and survival in head-and-neck squamous cell carcinoma 2011
2011 Radiation-induced ocular motor cranial nerve palsies in patients with pituitary tumorJournal of Neuro-Ophthalmology.  31:210-213. 2011
2011 Head and neck cancers: Clinical practice guidelines in oncology 2011
2011 Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with Radiation Therapy (RTOG 9003)Journal of Clinical Oncology.  29:1326-1334. 2011
2011 Dosimetric analysis of imaging changes following pulmonary stereotactic body radiation therapy 2011
2011 Improved clinical efficiency in CNS stereotactic radiosurgery using a flattening filter free linear accelerator.Journal of Radiosurgery and SBRT.  1:117-122. 2011
2010 Dosimetric Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Squamous Cell Carcinoma of the Head and Neck 2010
2010 Effects of Bladder Distension on Organs at Risk in 3D Image-Based Planning of Intracavitary Brachytherapy for Cervical Cancer 2010
2010 Margin on Gross Tumor Volume and Risk of Local Recurrence in Head-and-Neck Cancer 2010
2010 Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival 2010
2009 Postoperative reirradiation for mucosal head and neck squamous cell carcinomas 2009
2009 Development of an accelerated GVF semi-automatic contouring algorithm for radiotherapy treatment planningComputers in Biology and Medicine.  39:650-656. 2009
2009 Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Locally Advanced Head-and-Neck Cancer 2009
2009 NCCN Task Force Report: Management of dermatologic and other toxicities associated with EGFR inhibition in patients with cancer 2009
2008 Reirradiation and concurrent chemotherapy after salvage surgery: Pay now or pay laterJournal of Clinical Oncology.  26:5500-5501. 2008
2008 Locoregionally Advanced Head and Neck Cancer Treated With Primary Radiotherapy: A Comparison of the Addition of Cetuximab or Chemotherapy and the Impact of Protocol Treatment 2008
2008 Final report of RTOG 9610, a multi-institutional trial of reirradiation and chemotherapy for unresectable recurrent squamous cell carcinoma of the head and neck 2008
2008 Pretreatment Quality of Life Predicts for Locoregional Control in Head and Neck Cancer Patients: A Radiation Therapy Oncology Group Analysis 2008
2008 Head and neck cancers 2008
2008 Predictors of Distant Brain Recurrence for Patients With Newly Diagnosed Brain Metastases Treated With Stereotactic Radiosurgery Alone 2008
2007 SU‐FF‐J‐78: 3‐D Target Localization at the End of Expiration Prior to Respiration‐Gated Radiotherapy TreatmentMedical Physics.  34:2386. 2007
2007 SU‐FF‐T‐372: Registration of Frameless High‐Field MRI to Low‐Field Frame‐Based MRI Images in Leksell Gamma‐Knife (LGK) RadiosurgeryMedical Physics.  34:2487. 2007
2007 SU‐FF‐T‐426: Treatment Planning Comparison of Dynamic Multileaf Collimation and Helical Tomotherapy for Spinal Cord Sparing in Head and Neck Re‐IrradiationMedical Physics.  34:2499-2500. 2007
2006 Disadvantage of men living alone participating in radiation therapy oncology group head and neck trialsJournal of Clinical Oncology.  24:4177-4183. 2006
2006 Postoperative radiotherapy in non-small-cell lung cancer warrants further exploration in the era of adjuvant chemotherapy and conformal radiotherapyJournal of Clinical Oncology.  24:2978-2980. 2006
2006 An IMRT technique to increase therapeutic ratio of breast irradiation in patients with early stage left breast cancer: Limiting second malignancies.Journal of Clinical Oncology.  24:10791. 2006
2006 The authors and a colleague reply [11]New England Journal of Medicine.  354:2187. 2006
2006 Low-dose-rate vs. high-dose-rate intracavitary brachytherapy for carcinoma of the cervix: The University of Alabama at Birmingham (UAB) experienceBrachytherapy.  5:49-55. 2006
2006 Women with pathologic stage I, II, and III non-small cell lung cancer have better survival than menChest.  130:1796-1802. 2006
2005 Concomitant boost radiation plus concurrent cisplatin for advanced head and neck carcinomas: Radiation Therapy Oncology Group Phase II Trial 99-14Journal of Clinical Oncology.  23:3008-3015. 2005
2005 Pulmonary resection after high-dose and low-dose chest irradiationAnnals of Thoracic Surgery.  80:1224-1230. 2005
2005 Phase I/IIa study of cisplatin and gemcitabine as induction chemotherapy followed by concurrent chemoradiotherapy with gemcitabine and paclitaxel for locally advanced non-small-cell lung cancerJournal of Clinical Oncology.  23:6664-6673. 2005
2005 Is there disparity in the care of minority patients with upper aerodigestive tract malignancy?Medical Clinics of North America.  89:1033-1043. 2005
2005 Monte Carlo techniques for scattering foil design and dosimetry in total skin electron irradiations.Medical Physics.  32:1460-1468. 2005
2005 Head and neck cancers: Clinical practice guidelines 2005
2005 Monte Carlo techniques for scattering foil design and dosimetry in total skin electron irradiationsMedical Physics.  32:1460-1468. 2005
2005 SU‐FF‐J‐123: Residual Tumor Motion in Respiratory Gated CT Treatment PlaningMedical Physics.  32:1948. 2005
2005 SU‐FF‐T‐282: Beam Modifier Design for Total Skin Electron Irradiations Using Monte Carlo TechniquesMedical Physics.  32:2015. 2005
2005 Simultaneous optimization of sequential IMRT plansMedical Physics.  32:3257-3266. 2005
2004 A dynamic supraclavicular field-matching technique for head-and-neck cancer patients treated with IMRT 2004
2003 Docetaxel with concurrent radiotherapy in head and neck cancer.Seminars in Oncology.  30:89-93. 2003
2003 Role of radiation therapy and radiosurgery in glioblastoma multiforme 2003
2003 Phase 1 trial of combined chemotherapy and reirradiation for recurrent unresectable head and neck cancer 2003
2003 Validation of target volume and position in respiratory gated CT planning and treatmentMedical Physics.  30:3196-3205. 2003
2002 Concurrent chemoradiation therapy with cisplatin and paclitaxel for locally advanced non-small cell lung cancer: Long-term follow-up of a phase I trialLung Cancer.  37:189-199. 2002
2001 RTOG 96-10: Reirradiation with concurrent hydroxyurea and 5-fluorouracil in patients with squamous cell cancer of the head and neck 2001
2001 Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancerJournal of Clinical Oncology.  19:3234-3243. 2001
2000 Tumor shrinkage before intracavitary brachytherapy for cancer of the cervix: Radiotherapy alone versus concurrent chemoradiotherapy 2000
2000 Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers.Journal of Clinical Oncology.  18:47S-53S. 2000
2000 A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003 2000
2000 A prospective evaluation of the timing of postoperative radiotherapy for preventing heterotopic ossification following traumatic acetabular fractures 2000
2000 A phase I study of combined UFT plus leucovorin and radiotherapy for pancreatic cancer 2000
2000 NCCN Practice Guidelines for Head and Neck Cancers. 2000
1999 UFT/oral calcium folinate plus radiation in pancreatic cancer. 1999
1999 Monoclonal antibodies as potentiators of radiotherapy and chemotherapy in the management of head and neck cancerCurrent Opinion in Oncology.  11:187-190. 1999
1999 Chemoradiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (RTOG 85-01) 1999
1999 Multimodality therapy of patients with locally advanced squamous cell cancer of the head and neck: Preliminary results of two pilot trials using paclitaxel and cisplatinSeminars in Radiation Oncology.  9:64-69. 1999
1999 Phase I/IIa study of concurrent paclitaxel and cisplatin with radiation therapy m locally advanced non-small cell lung cancer: Analysis of early and late pulmonary morbiditySeminars in Radiation Oncology.  9:136-147. 1999
1999 Concomitant chemotherapy and reirradiation as management for recurrent cancer of the head and neck 1999
1998 Intratumoral cisplatin/epinephrine-injectable gel as a palliative treatment for accessible solid tumors: A multicenter pilot study 1998
1997 Sucralfate for radiation mucositis: Results of a double-blind randomized trial 1997
1997 An umbilical metastasis after laparoscopy for squamous cell carcinoma of the cervixGynecologic Oncology.  64:507-509. 1997
1996 Major geometric variations between intracavitary applications in carcinoma of the cervix: High dose rate vs. Low dose rate 1996
1996 Postsurgical recurrent carcinoma of the cervix: Reassessment and results of radiation therapy optionsRadiology.  201:559-563. 1996
1995 Initial clinical evaluation of iodine-125-labeled chimeric 17-1A for metastatic colon cancerJournal of Nuclear Medicine.  36:2229-2233. 1995
1995 Cisplatin plus radiation therapy.The Journal of infusional chemotherapy.  5:61-66. 1995
1995 Conventional four-field pelvic radiotherapy technique without computed tomography-treatment planning in cancer of the cervix: Potential geographic miss and its impact on pelvic control 1995
1995 Major geometric variations between multiple high-dose-rate applications of brachytherapy in cancer of the cervix: Frequency and types of variationRadiology.  195:419-422. 1995
1994 A clinically practical electron cone for the treatment of head and neck cancer 1994
1994 Conventional four-field pelvic radiotherapy technique without CT treatment planning in cancer of the cervix: potential geographic missRadiotherapy and Oncology.  30:140-145. 1994
1993 Malignant epidural spinal cord compression associated with a paravertebral mass: Its radiotherapeutic outcome on radiosensitivity 1993
1993 The influence of staging laparotomy for cervical cancer on patterns of recurrence and survival.International Journal of Gynecological Cancer.  3:169-174. 1993
1993 The influence of staging laparotomy for on patterns of recurrence and survival cervical cancerInternational Journal of Gynecological Cancer.  3:169-174. 1993
1992 A Phase I study of high-dose cisplatin, prolonged infusion 5- fluorouracil, and concomitant conventional fraction radiation therapy in patients with inoperable squamous cell carcinoma of the head and neck 1992
1992 Treatment of recurrent head and neck cancer with 5-fluorouracil, hydroxyurea, and reirradiation 1992
1991 A phase I study of prolonged infusion 5-fluorouracil and concomitant radiation therapy in patients with squamous cell cancer of the head and neck 1991
1991 Pharmacokinetics, immune response, and biodistribution of iodine-131-labeled chimeric mouse/human IgG1,k 17-1A monoclonal antibodyJournal of Nuclear Medicine.  32:1162-1168. 1991
1991 Three-port perineal sparing techniqueRadiology.  180:563-566. 1991
1990 Extradural spinal cord compression: Analysis of factors determining functional prognosis - Prospective studyRadiology.  176:279-282. 1990

Chapter

Year Title Altmetric
2010 Impact of dose rate on outcomes of Gamma Knife® radiosurgery in patients with face pain.  360-365. 2010

Principal Investigator On

Investigator On

  • Private Grant  awarded by ELI LILLY AND COMPANY 2019 - 2026
  • Private Grant  awarded by ELI LILLY AND COMPANY 2019 - 2024
  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group 2019 - 2024
  • NRG Oncology Member Institution Clinical Trial Fixed Price Subaward Agreement  awarded by NRG ONCOLOGY FOUNDATION 2019 - 2024
  • A Phase II Study of Durvalumab (MEDI 4736) with Radiotherapy for the adjuvant treatment of Intermediate Risk Head and Neck Squamous Cell Carcinoma  awarded by University of North Carolina at Chapel Hill 2020 - 2023
  • RTOG Foundation Master Service Agreement for Participation in Foundation Research: RTOG 3501 Tryhard: A Phase II, Randomized, Double Blind, Placebo-Controlled Study of Lapatinib (Tykerb) for Non-HPV Locally Advanced Head and Neck Cancer with Concurrent Chemoradiation  awarded by American College of Radiology 2012 - 2022
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2015 - 2021
  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group 2014 - 2020
  • UAB NRG Oncology Master Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2019
  • Private Grant  awarded by NOVOCURE, INC. 2017 - 2019
  • Private Grant  awarded by ELI LILLY AND COMPANY 2016 - 2019
  • UAB NRG Oncology Member Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2015 - 2019
  • UAB NRG Oncology Member Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2014 - 2019
  • Private Grant  awarded by VARIAN MEDICAL SYSTEMS, INC. 2014 - 2017
  • Food and Eating Behaviors of Head and Neck Cancer Patients  awarded by National Cancer Institute/NIH/DHHS 2012 - 2016
  • Private Grant  awarded by SPECTRUM PHARMACEUTICALS, INC. 2013 - 2016
  • Private Grant  awarded by DYNASPLINTT SYSTEM, INC. 2012 - 2015
  • Private Grant  awarded by ABBOTT LABORATORIES 2012 - 2014
  • Education And Training

  • Master of Science in Health / Health Care Administration / Management, University of Alabama at Birmingham 2004
  • Doctor of Medicine, University of Alabama at Birmingham 1983
  • UAB Hospital, Internship 1984
  • UAB Hospital, Residency 1987
  • Full Name

  • Sharon Spencer