Positions

Selected Publications

Academic Article

Year Title Altmetric
2014 Inhibitors of arachidonate-regulated calcium channel signaling suppress triggered activity induced by the late sodium current 2014
2013 Prolongation of minimal action potential duration in sustained fibrillation decreases complexity by transient destabilizationCardiovascular Research.  98:155-156. 2013
2012 Evidence that 2-aminoethoxydiphenyl borate provokes fibrillation in perfused rat hearts via voltage-independent calcium channels 2012
2011 Pharmacological evidence for Orai channel activation as a source of cardiac abnormal automaticity 2011
2007 A pharmacological model for calcium overload-induced tachycardia in isolated rat left atria 2007
2007 2-APB induces instability in rat left atrial mechanical activityJournal of Cardiovascular Pharmacology.  49:325-335. 2007
2004 Activation of leptin expression by an inhibitor of carnitine palmitoyltransferase-1International Journal of Obesity.  28:649-651. 2004
2002 Occupation of the prostaglandin E2-type 1 receptor increases rat atrial contractility via a Y-27632-sensitive pathwayProstaglandins.  70:91-105. 2002
1999 Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscleFree Radical Biology and Medicine.  27:1386-1392. 1999
1999 2-Tetradecylglycidic acid, an inhibitor of carnitine palmitoyltransferase-1, induces myocardial hypertrophy via the AT1 receptorJournal of Molecular and Cellular Cardiology.  31:1405-1412. 1999
1997 MDL-28170, a membrane-permeant calpain inhibitor, attenuates stunning and PKC(ε) proteolysis in reperfused ferret heartsCardiovascular Research.  35:60-67. 1997
1994 Estimates of beat to beat handling of activator calcium using measurements of [Ca2+]i in aequorin loaded ferret cardiac muscleCardiovascular Research.  28:40-46. 1994
1994 Estimates of beat to beat handling of activator calcium using measurements of [Ca2+]i in aequorin loaded ferret cardiac muscleCardiovascular Research.  28:40-46. 1994
1993 Beat-to-beat measurements of [Ca2+]i and force in ferret cardiac muscle after chemical loading of aequorinAmerican Journal of Physiology.  265. 1993
1993 A stable model of left ventricular dysfunction in an intact animal assessed with high fidelity pressure and cinemagnetic resonance imagingCardiovascular Research.  27:974-979. 1993
1993 A stable model of left ventricular dysfunction in an intact animal assessed with high fidelity pressure and cinemagnetic resonance imagingCardiovascular Research.  27:974-979. 1993
1993 Beat-to-beat measurements of [Ca2+](i) and force in ferret cardiac muscle after chemical loading of aequorinAmerican Journal of Physiology.  265. 1993
1993 Effects of hypoxia on intracellular calcium and contractility [1]Journal of Thoracic and Cardiovascular Surgery.  105:1114-1116. 1993
1992 Quantitative effects of sympathetic and vagal nerve stimulations on sinus and AV junctional rhythms 1992
1991 Cardiac parasympathetic efferent activities during myocardial ischemiaCoronary Artery Disease.  2:1031-1038. 1991
1991 Influence of ionic modification on electrical activity of Purkinje fibers obtained from dogs with 1-day-old myocardial infarctionJournal of Molecular and Cellular Cardiology.  23:31-39. 1991
1990 Excitation-contraction coupling model to estimate the recirculating fraction of activator calcium in intact cardiac muscleCanadian Journal of Physiology and Pharmacology.  68:1041-1048. 1990
1989 A method for rapid quantification of phosphorus metabolites in the isolated rat heart using P-31 NMRAmerican journal of cardiac imaging.  3:116-123. 1989
1989 Effects of ryanodine on contractile performance of intact length-clamped papillary muscleCirculation Research.  65:1270-1282. 1989
1988 Maximal twitch tension in intact length-clamped ferret papillary muscles evoked by modified postextrasystolic potentiationCirculation Research.  62:65-74. 1988
1987 The appearance and development of ventricular rhythm disorders in the 1st 24 hours after the start of experimental myocardial infarct in dogsKardiologiia.  27:63-70. 1987
1987 The effects of negative chronotropic interventions on sinus node recovery timeBasic Research in Cardiology.  82:92-100. 1987
1986 Differential effects of sympathetic activity on AV junctional automaticity and AV conductionBasic Research in Cardiology.  81:497-507. 1986
1986 Atrioventricular junctional tachycardia during heart blockJournal of the American College of Cardiology.  8:657-660. 1986
1986 Cardiac autonomic efferent activity during baroreflex in puppies and adult dogs 1986
1986 Differential inotropic actions of ethmozine and ethacizin (diethylamine analog of ethmozine)American Heart Journal.  111:462-465. 1986
1986 Differential interaction of adrenergic and cholinergic effects on AV junctional automaticity and AV conductionAmerican Heart Journal.  112:765-770. 1986
1986 Differential modulation of autonomic activity by ethmozin and ethacizin (analog of ethmozin) on the canine sinus node and atrioventricular junctionJournal of the American College of Cardiology.  8:86A-94A. 1986
1986 Differential sympathetic-parasympathetic interactions in sinus node and AV junction 1986
1986 Effects of ethacizin (diethylamino analogue of ethmozin) upon sympathetic and parasympathetic efferent activity to the canine heartKardiologiia.  26:54-60. 1986
1986 Effects of the diethylamino analog of ethmozin (ethacizin) upon sympathetic and parasympathetic efferent activity to the canine heartJournal of Pharmacology and Experimental Therapeutics.  236:75-79. 1986
1986 Role of calcium channel blockers in clinical medicineAmerican Journal of the Medical Sciences.  292:217-230. 1986
1986 Serial production of controlled periods of temporary heart block used to unmask and assess latent ventricular automaticity during experimental acute myocardial ischemiaJournal of the American College of Cardiology.  8:95A-103A. 1986
1986 The direct negative inotropic effect of gossypolJournal of Ethnopharmacology.  17:31-36. 1986
1986 Ventricular echo beats during ventricular pacing or junctional bradycardia: Studies in the normal canine heartAmerican Heart Journal.  111:672-678. 1986
1985 Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction.American Journal of Physiology.  248. 1985
1985 Differences in the determinants of overdrive suppression between sinus rhythm and slow atrioventricular junctional rhythmCirculation Research.  57:182-191. 1985
1985 Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction 1985
1984 Arrhythmias and antiarrhythmic drugs.The Alabama journal of medical sciences.  21:275-283. 1984
1984 Indirect stimulatory action of the calcium channel blocker AQA-39Journal of Pharmacology and Experimental Therapeutics.  230:336-340. 1984
1984 No electrical instability after intracoronary streptokinase administered into sinus node or AV node of dogsAmerican Heart Journal.  107:902-905. 1984
1984 Parasympathetic and sympathetic efferent traffic during a cardiogenic hypertensive chemoreflexCardiovascular Research.  18:583-590. 1984
1983 Acute effects of amiodarone upon the canine sinus node and atrioventricular junctional regionJournal of Clinical Investigation.  71:1457-1466. 1983
1983 Differential effect of verapamil isomers on sinus node and AV junctional region 1983
1983 Differential effect of verapamil isomers on sinus node and AV junctional region.American Journal of Physiology.  244. 1983
1983 Studies of changes in breathing and blood pressure accompanying a cardiogenic hypertensive chemoreflex compared in conscious and anesthetized dogsAmerican Heart Journal.  106:547-553. 1983
1983 Ventricular flutter during treatment with amiodaroneAmerican Journal of Cardiology.  51:609-610. 1983
1982 Post-excitatory depression in thoracic sympathetic efferent neural traffic during a cardiogenic hypertensive chemoreflexBasic Research in Cardiology.  77:423-430. 1982
1982 The direct negative chronotropic action of prazosin on the canine sinus nodeJournal of Pharmacology and Experimental Therapeutics.  221:801-805. 1982
1982 The immediate electrophysiologic effects of amiodarone on the canine sinus node and AV junctional regionAmerican Journal of Cardiology.  49:981. 1982
1982 Ultrastructure of a coronary chemoreceptor of dogs and catsJournal of Molecular and Cellular Cardiology.  14:711-724. 1982
1981 Absence of electrophysiological effect by intracoronary streptokinase administered directly into arteries supplying sinus node or AV node of dogClinical research.  29. 1981
1981 Clonidine attenuation of a cardiogenic hypertensive chemoreflexHypertension.  3:240-244. 1981
1981 Direct effects of prazosin on the canine sinus nodeAmerican Journal of Cardiology.  47:389. 1981
1981 Effects of adenosine on mechanical performance and electrical activity in the canine heartJournal of Pharmacology and Experimental Therapeutics.  216:254-260. 1981
1981 Effects of selectively produced changes in cardiac rhythm or conduction upon flow in the superior vena cavaJournal of Thoracic and Cardiovascular Surgery.  82:447-456. 1981
1981 Effects of tetraethylammonium and 4-aminopyridine upon canine sinus nodeJournal of Molecular and Cellular Cardiology.  13:889-901. 1981
1981 Electrical activity in canine sinus node cells during arrest produced by acetylcholineJournal of Molecular and Cellular Cardiology.  13:349-357. 1981
1981 Rate dependence of the negative inotropic action of adenosineClinical research.  29. 1981
1981 The differential and rate dependent effect of the isomers of verapamil on sinus node and AV junctional automaticityPhysiologist.  24. 1981
1981 The immediate electrophysiologic effects of amiodarone on the canine sinus node and AV junctional regionClinical research.  29. 1981
1980 Analysis of sympathetic discharges during cardiogenic hypertensive chemoreflex 1980
1980 Blocking Effects of Cyproheptadine and Methysergide upon Two Different Cardiovascular Responses to Serotonin 1980
1980 Changing negative inotropic effect of acetylcholine in maturing canine cardiac muscle 1980
1980 Changing negative inotropic effect of acetylcholine in maturing canine cardiac muscle.American Journal of Physiology.  238. 1980
1980 Dilatation of coronary artery stenoses after isosorbide dinitrate in man 1980
1980 Dilatation of coronary stenoses after isosorbide dinitrate 1980
1980 Direct effects of prazosin on the canine sinus nodeClinical research.  28. 1980
1980 Hierarchy of supraventricular pacemakersJournal of Thoracic and Cardiovascular Surgery.  80:750-753. 1980
1980 Quantitative difference in 'critical' stenosis between right and left coronary artery in manCirculation.  62:1188-1196. 1980
1980 Reflex heart block. Baroreflex, chemoreflex and bronchopulmonary reflex causesAmerican Journal of Cardiology.  45:1182-1188. 1980
1980 Regional flow patterns during the serotonin-induced cardiogenic hypertensive chemoreflexCardiovascular Research.  14:169-176. 1980
1980 Selective effects of clonidine on the canine sinus nodeJournal of Pharmacology and Experimental Therapeutics.  214:223-228. 1980
1979 Morphological changes in the right ventricular septomarginal trabecula (false tendon) during maturation and ageing in the dog heartJournal of Anatomy.  129:805-817. 1979
1979 Termination of 'ventricular' arrhythmias from digoxin by selective production of complete atrioventricular block with physostigmine in the dogJournal of Pharmacology and Experimental Therapeutics.  211:561-570. 1979
1979 Anatomic and physiologic considerations of a cardiogenic hypertensive chemoreflexAmerican Journal of Cardiology.  44:852-859. 1979
1979 Experimental studies on the pathogenesis of asystole after verapamil in the dogAmerican Journal of Cardiology.  44:651-656. 1979
1979 Asystole after nifedipineClinical research.  27. 1979
1979 Chronotropic and dromotropic effects of histamine on the canine heartChest.  75:597-604. 1979
1979 Correlative electrophysiological and anatomical studies concerning the site of origin of escape rhythm during complete atrioventricular block in the dogCirculation Research.  45:108-119. 1979
1979 Dual dependence on both Ca2+ and Mg2+ for electrical stability in cells of canine false tendonJournal of Molecular and Cellular Cardiology.  11. 1979
1979 Effects of clonidine upon the thoracic sympathetic efferent discharges of a cardiogenic hypertensive chemoreflexPhysiologist.  22:50. 1979
1979 Effects of verapamil on automaticity and conduction with particular reference to tachyphylaxis 1979
1979 Electrophysiological effects of magnesium on cells in the canine sinus node and false tendonCirculation Research.  44:182-188. 1979
1979 Fine Structure of Myotendinous Junctions of Ventricular Papillary Muscles of the Cat (Feus Domestica) and Bat (Myotis Lucifugus)Circulation Journal.  43:547-569. 1979
1979 Mechanism of postarrhythmic renal vasoconstriction in the anesthetized dogJournal of Clinical Investigation.  64:17-31. 1979
1978 Progressive postnatal changes in sinus node response to atropine and propranolol.American Journal of Physiology.  234. 1978
1978 Canine atrial and ventricular muscle mechanics studies as a function of ageCirculation Research.  42:703-713. 1978
1978 Chronotropic effects of tetraethylammonium and 4-aminopyridine in canine sinus node pacemaker cellsCirculation.  58. 1978
1978 Hemodynamic components of a cardiogenic hypertensive chemoreflex in dogsCirculation Research.  42:135-142. 1978
1978 Neural pathways of a cardiogenic hypertensive chemoreflex 1978
1978 Neural pathways of a cardiogenic hypertensive chemoreflex 1978
1978 New arterial hypertension during myocardial infarctionSouthern Medical Journal.  71:289-292. 1978
1978 Progressive postnatal changes in sinus node response to atropine and propranolol 1978
1978 The effect of aging on ventricular contractile performanceAmerican Heart Journal.  96:481-485. 1978
1978 The mechanism of post-arrhythmic renal vasoconstriction in the dogCirculation.  58. 1978
1977 A mathematical model of automaticity in the sinus node and AV junction based on weakly coupled relaxation oscillators 1977
1977 Chemoreceptors of the heart 1977
1977 Chronotropic and dromotropic effects of histamine (H 1 and H 2) agonists upon the canine heartPhysiologist.  20:39. 1977
1977 Cyproheptadine Blockade of a Cardiogenic Hypertensive Chemoreflex 1977
1977 Differential sensitivity to neurotransmitters in denervated canine sinus node 1977
1976 Fine structure of the conduction system and working myocardium in the little brown bat, Myotis lucifugus. 1976
1976 Both direct and neurally mediated components of the chronotropic actions of aminophyllineChest.  70:24-32. 1976
1976 Comparison of the inotropic action of morphine and ketamine studied in canine cardiac muscle.Journal of Thoracic and Cardiovascular Surgery.  72:142-149. 1976
1976 Influence of [Mg2+] on activity of sinus node pacemaker cellsCirculation.  54. 1976
1976 Sinus bradyarrhythmia and impaired response to norepinephrine caused by low extracellular sodiumCirculation.  54. 1976
1976 Spontaneous action potentials of cells in the canine sinus nodeCirculation Research.  39:76-82. 1976
1975 A comparison of His bundle electrograms recorded from the aortic root and from a plaque sutured near the His bundle 1975
1975 Absence of supersensitivity to acetylcholine in the extrinsically denervated canine sinus nodePhysiologist.  18:236. 1975
1975 Analysis of components in a cardiogenic hyertensive chemoreflexCirculation.  52:179-192. 1975
1975 Canine atrial and ventricular muscle mechanics studied as a function of ageCirculation.  52. 1975
1975 Comparison of contractile performance of canine atrial and ventricular musclesCirculation Research.  37:762-771. 1975
1975 Direct and vagally mediated chronotropic effects of morphine studied by selective perfusion of the sinus node of awake dogsChest.  68:222-228. 1975
1974 Comparative effects of glucagon on automaticity of the sinus node and atrioventricular junction.American Journal of Physiology.  227:1415-1421. 1974
1974 Electrophysiological and mathematical characteristics of the escape rhythm during complete AV blockCardiovascular Research.  8:173-186. 1974
1974 Fine structure of the bundle branches 1974
1974 Morphine selectively perfused into the sinus node of awake dogsCirculation.  50. 1974
1974 Prostaglandins and autonomic control of the sinus nodeALA.J.MED.SCI..  11:82. 1974
1974 Selective effects of pentobarbital on automaticity and conduction in the intact canine heartCardiovascular Research.  8:46-57. 1974
1973 Comparatve dependence on adrenergic neural tone by automaticity in the sinus node and in the atrioventricular junctionJournal of Pharmacology and Experimental Therapeutics.  187:269-279. 1973
1973 Effect of tetrodotoxin on A-V conduction and A-V junctional rhythm.American Journal of Physiology.  224:1155-1161. 1973
1973 Mathematical relationship between automaticity of the sinus node and the AV junctionAmerican Heart Journal.  86:189-195. 1973
1973 Morphine and autonomic control of the sinus nodeChest.  64:203-212. 1973
1973 Neurogenic influence on the atrial repolarization (P-Tp) segmentAmerican Journal of Cardiology.  32:799-807. 1973
1973 Prostaglandins and autonomic control of the sinus nodeClinical research.  22. 1973
1972 Effects of adenosine and ATP on AV conduction and on AV junctional rhythm 1972
1971 Pharmacologic production of atrioventricular block with and without initial bundle branch block.Journal of Pharmacology and Experimental Therapeutics.  179:338-346. 1971
1971 Changes in the clinical picture of infectious endocarditisSwiss Medical Weekly.  101:105-109. 1971
1970 Löfgren's Syndrome. Incidence and course of Boeck's diseaseSwiss Medical Weekly.  100:1111-1113. 1970
1969 Rhythm disorders in acute myocardial infarct. Experience with 370 patients at a coronary care unit 1969

Education And Training

  • Doctor of Medicine, University of Zurich 1963
  • Full Name

  • Ferdinand Urthaler