• Citations (Scopus)=6,377; h-index=38. Cites to Zika papers=270 and to COVID papers=1,310

    David O. Freedman is Professor Emeritus of Infectious Diseases. After spending 28 years as an Infectious Diseases faculty member at the University of Alabama at Birmingham and 15 years co-appointed as a Professor of Epidemiology in UAB’s School of Public Health, since 2016, Dr. David Freedman has been an Emeritus Professor and remained active on a full-time basis at UAB as well as in other spheres. He received a BSc (Hons) in Physiology from McGill and an MD from the University of Toronto, followed by training in Internal Medicine and Infectious diseases at McGill University and 5 years as a post-doc at the Laboratory of Parasitic Diseases, NIH. Over the last 35 years, Prof. Freedman has spent roughly 20% of his time overseas, where he has conducted translational research, taught, and developed sentinel surveillance networks and multi-sectorial partnerships in the governmental, diplomatic, military, and private sectors. In recent years he has spent most of his time editing and creating content for publications such as the Emerg. Infect. Dis. Journal, J. Travel Med, Travax, and the Sanford Guide

    He founded the UAB Travelers Health Clinic in 1989. He is Past-President, Clinical Group American Society of Tropical Medicine and Hygiene (ASTMH) and Past Secretary-Treasurer of the International Society of Travel Medicine (ISTM). He is an Editor of the Textbook of Travel Medicine now in its 3rd Edition; Associate Editor, Emerging Infectious Diseases Journal and is on the Editorial Board of the Journal of Travel Medicine. For 20 years he was Director of the global GeoSentinel Surveillance Network which he co-founded and which maintains the largest database of ill travelers available. He founded and is now a Visiting Professor each year at the Gorgas Course in Clinical Tropical Medicine given annually in Peru. He is a co-author of the IDSA Clinical Practice Guidelines on Travel Medicine. His research focused on clinical tropical medicine and immuno-parasitology, including the development of surveillance networks to characterize infectious disease morbidity in travelers and migrants. He was a Member of the VA Merit Review Infectious Diseases Study Section (1997-2000), Chair of the Advisory Panel on Parasitic Diseases of the US Pharmacopeia (1995-2000), and a Councilor of the American Society of Tropical Medicine and Hygiene (1998-2002). Funded research projects have been completed in India, Guatemala, Ghana, Brazil, and Peru in addition to the 24 countries where GeoSentinel sites have been established.

    Selected Awards, Honors and Service:

    World Health Organization--Member, International Health Regulations (IHR) Emergency Committee on Zika Virus 
    World Health Organization--Member, Roster of Experts, IHR 
    Honorary University-Wide Professor, Universidad Peruana Cayetano Heredia, Lima Peru. Due to his longstanding and remarkable collaboration to the teaching and research activities at our institution.
    Sir Macfarlane Burnet Oration. Australian Society of Infectious Diseases Annual Scientific Conference.
    Honor Award, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Ga.  For the development of a worldwide network that has excelled in detecting and communicating  trends in travel-related morbidity
    James H. Nakano Award. For an outstanding scientific paper published by CDC in 2006.  CDC, Atlanta, Ga.  
    Annual listing in “Best Doctors in America” 2005-2021
    Oswaldo Cruz Foundation Centennial Medal.  For outstanding contributions to the development of the Aggeu Magalhaes Research Institute, Recife Brazil
    Permanent Member, Merit Review Study Section, Infectious Diseases, Veterans Administration (1997-2000)
    Persian Gulf Expert Committee, (Chartered Committee; direct reporting to the Secretary), Department of Veterans Affairs, Washington, DC.  
    Chair, Expert Advisory Panel on Parasitic Disease Therapy, United States Pharmacopeia (USP).  1995-2000
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Air travel and SARS-CoV-2: many remaining knowledge gapsJournal of Travel Medicine.  29. 2022
    2021 COVID-19 immunity passport to ease travel restrictions?Journal of Travel Medicine.  27:1-3. 2021
    2021 GeoSentinel: Past, present and futureJournal of Travel Medicine.  27. 2021
    2020 Isolation, quarantine, social distancing and community containment: Pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreakJournal of Travel Medicine.  27. 2020
    2020 In Memoriam: Jay Stephen Keystone (1943-2019). 2020
    2020 In-flight transmission of SARS-CoV-2: A review of the attack rates and available data on the efficacy of face masksJournal of Travel Medicine.  27. 2020
    2020 Updated yellow fever entry requirements and recommendations from WHO as of August 2020Journal of Travel Medicine.  27. 2020
    2019 Ambient Air Pollution and Mortality in 652 CitiesNew England Journal of Medicine.  381:2073-2074. 2019
    2019 Vaccines for International TravelMayo Clinic Proceedings.  94:2314-2339. 2019
    2019 Tafenoquine and g6pd: A primer for cliniciansJournal of Travel Medicine.  26. 2019
    2019 Tafenoquine: Integrating a new drug for malaria prophylaxis into travel medicine practiceJournal of Travel Medicine.  26. 2019
    2018 Updated Zika virus recommendations are needed 2018
    2018 Medical considerations before international travel and infections in returning travelersInternational Journal of Infectious Diseases.  73:59. 2018
    2017 Response to "selection bias"CMAJ.  189:E674. 2017
    2017 Surveillance report of Zika virus among Canadian travellers returning from the AmericasCMAJ.  189:E334-E340. 2017
    2017 Underestimate of annual malaria imports to CanadaLancet Infectious Diseases.  17:141-142. 2017
    2016 Medical Considerations before International Travel.New England Journal of Medicine.  375:e32. 2016
    2016 The authors replyNew England Journal of Medicine.  375:e232. 2016
    2016 Should testing of donors be restricted to active Zika virus areas?Lancet Infectious Diseases.  16:1108-1109. 2016
    2016 Illness in Canadian travellers and migrants from Brazil: CanTravNet surveillance data, 2013-2016. 2016
    2016 Medical considerations before international travelNew England Journal of Medicine.  375:247-260. 2016
    2016 Chikungunya in travellers returning to Canada: Surveillance report from cantravnet surveillance data, 2006 to 2015 2016
    2016 Re-born in the USA: Another cholera vaccine for travellersTravel Medicine and Infectious Disease.  14:295-296. 2016
    2016 Zika virus and microcephaly: Why is this situation a PHEIC? 2016
    2016 Malaria in travellers returning or migrating to Canada: surveillance report from CanTravNet surveillance data, 2004-2014.CMAJ open.  4:E352-E358. 2016
    2016 Thoracic damage control surgery.Revista do Colégio Brasileiro de Cirurgiões.  43:374-381. 2016
    2015 Imminent Departures: Rapid Vaccination Strategies Designed to Induce Short-Term Immunogenicity for the Trip at HandJournal of Travel Medicine.  22:219-220. 2015
    2015 Dermatoses among returned Canadian travellers and immigrants: surveillance report based on CanTravNet data, 2009-2012.CMAJ open.  3:E119-E126. 2015
    2014 Travel-acquired infections in Canada: CanTravNet 2011-2012. 2014
    2014 Postgraduate training in tropical medicine: The value of on-site experienceInternational Journal of Infectious Diseases.  21:78. 2014
    2014 Travel-acquired infections and illnesses in canadians: Surveillance report from CanTravNet surveillance data, 2009-2011Open Medicine.  8:20-32. 2014
    2013 Detection on four continents of dengue fever cases related to an ongoing outbreak in Luanda, Angola, March to May 2013.Eurosurveillance.  18. 2013
    2013 Surveillance for travel-related disease--GeoSentinel Surveillance System, United States, 1997-2011. 2013
    2013 Travel-associated illness trends and clusters, 2000-2010 2013
    2013 International travelers as sentinels for sustained influenza transmission during the 2009 influenza A(H1N1)pdm09 pandemicJournal of Travel Medicine.  20:177-184. 2013
    2013 Acute and potentially life-threatening tropical diseases in western travelers - A GeoSentinel multicenter study, 1996-2011American Journal of Tropical Medicine and Hygiene.  88:397-404. 2013
    2013 Detection on four continents of dengue fever cases related to an ongoing outbreak in Luanda, Angola, March to May 2013Eurosurveillance.  18:20488. 2013
    2013 GeoSentinel surveillance of illness in returned travelers, 2007-2011ACP journal club.  158:456-468. 2013
    2013 Surveillance for travel-related disease - GeoSentinel surveillance system, United States, 1997-2011 2013
    2012 Expatriates ill after travel: Results from the Geosentinel Surveillance NetworkBMC Infectious Diseases.  12. 2012
    2012 Ongoing outbreak of an acute muscular Sarcocystis-like illness among travellers returning from Tioman Island, Malaysia, 2011-2012Eurosurveillance.  17. 2012
    2012 Notes from the field: Acute muscular sarcocystosis among returning travelers-Tioman island, Malaysia, 2011 2012
    2012 Characteristics and spectrum of disease among ill returned travelers from pre- and post-earthquake Haiti: The geosentinel experienceAmerican Journal of Tropical Medicine and Hygiene.  86:23-28. 2012
    2010 Sex and gender differences in travel-associated diseaseClinical Infectious Diseases.  50:826-832. 2010
    2010 Short report: Health risks in travelers to South Africa: The geosentinel experience and implications for the 2010 FIFA World CupAmerican Journal of Tropical Medicine and Hygiene.  82:991-995. 2010
    2010 Travel medicine, a speciality on the moveClinical Microbiology and Infection.  16:201-202. 2010
    2009 Globally mobile populations and the spread of emerging pathogens 2009
    2009 Global health surveillance and travelers' healthCurrent Opinion in Infectious Diseases.  22:423-429. 2009
    2009 Japanese encephalitis: Is there a need for a novel vaccine?Expert Review of Vaccines.  8:969-972. 2009
    2009 Expert opinion on vaccination of travelers against Japanese encephalitisJournal of Travel Medicine.  16:204-216. 2009
    2009 Imported human African trypanosomiasis in Europe, 2005-2009.Eurosurveillance.  14. 2009
    2008 The author repliesNew England Journal of Medicine.  359:2293-2294. 2008
    2008 Should health-care providers in the United States have access to influenza vaccines formulated for the southern hemisphere?Journal of Travel Medicine.  15:442-446. 2008
    2008 Malaria prevention in short-term travelersNew England Journal of Medicine.  359:603-612. 2008
    2008 A comparative analysis of methodological approaches used for estimating risk in travel medicineJournal of Travel Medicine.  15:263-272. 2008
    2008 Gastrointestinal infection among international travelers globallyJournal of Travel Medicine.  15:221-228. 2008
    2008 Health risks in travelers to China: the GeoSentinel experience and implications for the 2008 Beijing Olympics.American Journal of Tropical Medicine and Hygiene.  79:4-8. 2008
    2008 Seasonality, annual trends, and characteristics of dengue among Ill returned travelers, 1997-2006 2008
    2008 Reply to ConnorClinical Infectious Diseases.  46:476-477. 2008
    2008 Characteristics of schistosomiasis in travelers reported to the GeoSentinel Surveillance Network 1997-2008American Journal of Tropical Medicine and Hygiene.  79:729-734. 2008
    2008 Natural history, clinicoradiologic correlates, and response to triclabendazole in acute massive fascioliasisAmerican Journal of Tropical Medicine and Hygiene.  78:222-227. 2008
    2008 Short report: Health risks in travelers to China: The GeoSentinel experience and implications for the 2008 Beijing olympicsAmerican Journal of Tropical Medicine and Hygiene.  79:4-8. 2008
    2008 The revised International Health Regulations (2005): Impact on yellow fever vaccination in clinical practiceAmerican Journal of Tropical Medicine and Hygiene.  78:359-360. 2008
    2007 Filariasis in travelers presenting to the GeoSentinel Surveillance NetworkPLoS Neglected Tropical Diseases.  1. 2007
    2007 Etiology of travel-related feverCurrent Opinion in Infectious Diseases.  20:449-453. 2007
    2007 Drug-free holidays: Pre-travel versus during travel malaria chemoprophylaxisAmerican Journal of Tropical Medicine and Hygiene.  77:1-2. 2007
    2007 Reply to Behrens et al. [4]Clinical Infectious Diseases.  44:762-763. 2007
    2006 The practice of travel medicine: Guidelines by the infectious diseases society of AmericaClinical Infectious Diseases.  43:1499-1539. 2006
    2006 Caring for the caregivers [2]Journal of Travel Medicine.  13:384. 2006
    2006 The authors reply [13]New England Journal of Medicine.  354:1851. 2006
    2006 Spectrum of disease and relation to place of exposure among ill returned travelersNew England Journal of Medicine.  354:119-130. 2006
    2006 Infectious risks in travelersRevue Francaise des Laboratoires.  2006:18. 2006
    2005 Influenza: Changing approaches to prevention and treatment in travelersJournal of Travel Medicine.  12:36-44. 2005
    2005 Prevalence and predictors of intestinal helminth infections among human immunodeficiency virus type 1-infected adults in an urban African settingAmerican Journal of Tropical Medicine and Hygiene.  73:777-782. 2005
    2004 Transparency in publishingJournal of Travel Medicine.  11:263-264. 2004
    2003 Confronting the New Challenge in Travel Medicine: SARSJournal of Travel Medicine.  10:257-258. 2003
    2003 SARS - Lessons learned so farTravel Medicine and Infectious Disease.  1:67-68. 2003
    2002 Sexual behavior of international travelers visiting PeruSexually Transmitted Diseases.  29:510-513. 2002
    2002 Educational programs to enhance medical expertise in tropical diseases: The Gorgas Course experience 1996-2001American Journal of Tropical Medicine and Hygiene.  66:526-532. 2002
    2002 Treatment failure in intestinal strongyloidiasis: An indicator of HTLV-I infectionInternational Journal of Infectious Diseases.  6:28-30. 2002
    2001 TAP1 polymorphisms in several human ethnic groups: Characteristics, evolution, and genotyping strategiesHuman Immunology.  62:256-268. 2001
    2001 Effect of aggressive prolonged diethylcarbamazine therapy on circulating antigen levels in bancroftian filariasisTropical Medicine and International Health.  6:37-41. 2001
    2001 Internet and computer-based resources for travel medicine practitionersClinical Infectious Diseases.  32:757-765. 2001
    2001 Advanced age a risk factor for illness temporally associated with yellow fever vaccination 2001
    2001 Cashew nut dermatitis in a returned travelerJournal of Travel Medicine.  8:213-215. 2001
    2001 Evaluation of the effectiveness of an international diploma course in tropical medicineJournal of Continuing Education in the Health Professions.  21:97-102. 2001
    2001 Genotyping TAP2 variants in North American Caucasians, Brazilians, and AfricansGenes and Immunity.  2:32-40. 2001
    1999 Emerging infectious diseases and risk to the travelerMedical Clinics of North America.  83:865-883. 1999
    1999 Biased TCR repertoire in infiltrating lesional T cells in human bancroftian filariasisJournal of Immunology.  162:1756-1764. 1999
    1999 Epidemiology and immunopathology of bancroftian filariasis 1999
    1999 GeoSentinel: The global emerging infections sentinel network of the International Society of Travel MedicineJournal of Travel Medicine.  6:94-98. 1999
    1999 Strongyloides stercoralis hyperinfection associated with human T cell lymphotropic virus type-1 infection in PeruAmerican Journal of Tropical Medicine and Hygiene.  60:146-149. 1999
    1998 Immune dynamics in the pathogenesis of human lymphatic filariasisTrends in Parasitology.  14:229-234. 1998
    1998 Differences in the Frequency of Cytokine-Producing Cells in Antigenemic and Nonantigenemic Individuals with Bancroftian FilariasisInfection and Immunity.  66:1377-1383. 1998
    1998 Keeping current. Travel medicine resources available on the Internet.Infectious Disease Clinics of North America.  12:543-547. 1998
    1998 PrefaceInfectious Disease Clinics of North America.  12:17a. 1998
    1997 Field trial of a rapid card test for Wuchereria bancrofti 1997
    1997 Rapid Internet Survey: An Effective New Research Tool in Travel Medicine.Journal of Travel Medicine.  4:57. 1997
    1997 T-lymphocytes from individuals with filarial inflammatory disease have increased transendothelial migration in vitroClinical Immunology.  82:216-220. 1997
    1996 Very late antigen-4/vascular cell adhesion molecule-1 (VLA-4/VCAM-1) pathway is involved in the transendothelial migration of Lymphocytes in Bancroftian FilariasisJournal of Immunology.  156:2901-2908. 1996
    1996 Immunoregulation in onchocerciasis: Persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigenJournal of Infectious Diseases.  174:380-386. 1996
    1996 The presence or absence of active infection, not clinical status, is most closely associated with cytokine responses in lymphatic filariasisJournal of Infectious Diseases.  173:1453-1459. 1996
    1995 Predominant CD8+ infiltrate in limb biopsies of individuals with filarial lymphedema and elephantiasisAmerican Journal of Tropical Medicine and Hygiene.  53:633-638. 1995
    1995 Abnormal lymphatic function in presymptomatic bancroftian filariasisJournal of Infectious Diseases.  171:997-1001. 1995
    1995 Lymphoscintigraphic assessment of the effect of diethylcarbamazine treatment on lymphatic damage in human bancroftian filariasisAmerican Journal of Tropical Medicine and Hygiene.  52:258-261. 1995
    1994 Travel medicineCurrent Opinion in Infectious Diseases.  7:570-574. 1994
    1994 Cloning and characterization of a potentially protective chitinase-like recombinant antigen from Wuchereria bancroftiInfection and Immunity.  62:1901-1908. 1994
    1994 Lymphoscintigraphic analysis of lymphatic abnormalities in symptomatic and asymptomatic human filariasisJournal of Infectious Diseases.  170:927-933. 1994
    1994 The Onchocerca volvulus homologue of the multifunctional polypeptide protein disulfide isomeraseMolecular and Biochemical Parasitology.  68:103-117. 1994
    1994 Truly infection-free persons are rare in areas hyperendemic for african onchocerciasisJournal of Infectious Diseases.  170:1054-1055. 1994
    1992 Imported malaria-here to stayAmerican Journal of Medicine.  93:239-242. 1992
    1992 Rapid diagnosis of bancroftian filariasis by acridine orange staining of centrifuged parasitesAmerican Journal of Tropical Medicine and Hygiene.  47:787-793. 1992
    1991 Experimental infection of human subjects with Strongyloides speciesClinical Infectious Diseases.  13:1221-1226. 1991
    1991 Immunoregulation in onchocerciasis: Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapyJournal of Clinical Investigation.  88:231-238. 1991
    1990 Measles vaccine and travelers (I)ACP journal club.  112:475. 1990
    1989 Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic areaJournal of Clinical Investigation.  83:14-22. 1989
    1989 Selective up-regulation of endothelial cell class I MHC expression by cytokines from patients with lymphatic filariasisJournal of Immunology.  142:653-658. 1989
    1989 The Efficacy of Ivermectin in the Chemotherapy of Gastrointestinal Helminthiasis in HumansJournal of Infectious Diseases.  159:1151-1153. 1989
    1988 Eggs of schistosoma mansoni stimulate endothelial cell proliferation in vitroJournal of Infectious Diseases.  158:556-562. 1988
    1988 Enhanced solubilization of immunoreactive proteins from Brugia malayi adult parasites using cetyltrimethylammonium bromideExperimental Parasitology.  65:244-250. 1988
    1987 Loiasis in an expatriate American child: Diagnostic and treatment difficultiesPediatrics.  80:943-946. 1987
    1987 A case of laboratory acquired Leishmania donovani infection; evidence for primary lymphatic disseminationTransactions of the Royal Society of Tropical Medicine and Hygiene.  81:118-119. 1987


    Year Title Altmetric
    2012 Travel Medicine: Third Edition 2012
    2009 Introduction 2009
    2008 Travel Medicine: Second Edition 2008
    2008 Travel Medicine 2008


    Year Title Altmetric
    2014 Infections in Returning Travelers.  3568-3577. 2014
    2014 Protection of Travelers.  3559-3567. 2014
    2013 Personal Security and Crime Avoidance.  463-466. 2013
    2013 Sources of Travel Medicine Information.  25-30. 2013
    2011 Detection of Infectious Diseases Using Unofficial Sources.  11-21. 2011
    2010 Travelers as Sentinels for Disease Occurrence in Destination Countries.  27-34. 2010
    2009 Advising Travelers with Specific Needs.  457-492. 2009
    2009 Conveyance and Transportation Issues.  412-427. 2009
    2009 Health Considerations for Newly Arrived Immigrants and Refugees.  493-500. 2009
    2009 International Travel with Infants and Children.  428-456. 2009
    2009 Select Destinations and Travel Itineraries.  242-269. 2009
    2009 Chapter 3 Select Destinations and Travel Itineraries.  242-269. 2009
    2009 Chapter 8 Advising Travelers with Specific Needs.  457-492. 2009
    2008 Immunization of Healthy Adults.  85-120. 2008
    2008 Personal Security and Crime Avoidance.  501-504. 2008
    2008 Sources of Travel Medicine Information.  29-34. 2008
    2008 Chapter 10 Immunization of Healthy Adults.  85-120. 2008
    2008 Chapter 4 Sources of Travel Medicine Information.  29-34. 2008
    2008 Chapter 51 Personal Security and Crime Avoidance.  501-504. 2008
    2007 The borneo eco-challenge: GeoSentinel and rapid global sharing of disease outbreak information.  129-135. 2007
    2006 Onchocerciasis.  1176-1188. 2006
    2006 Chapter 1 Introduction.  1-18. 2006
    2006 Chapter 100 Onchocerciasis.  1176-1188. 2006
    2005 Onchocerciasis.  1176-1188. 2005

    Education And Training

  • Montreal General Hospital, Internship
  • Montreal General Hospital, Residency
  • Lab of Parasitic Diseases, Postdoctoral Fellowship
  • Montreal General Hospital, Postdoctoral Fellowship
  • National Institute of Health, Postdoctoral Fellowship
  • Doctor of Medicine, 1981
  • Bachelor of Science or Mathematics in Physiology, 1977
  • Full Name

  • David Freedman