Positions

Overview

  • David O. Freedman is Professor of Medicine and Epidemiology and founded the UAB Travelers Health Clinic in 1989. He is Past-President, Clinical Group American Society of Tropical Medicine and Hygiene (ASTMH) and Past Secretary-Treasurer of the International Society of Travel Medicine (ISTM). He is an Editor of the Textbook of Travel Medicine now in its 3rd Edition; Associate Editor, Emerging Infectious Diseases Journal and is on the Editorial Board of the Journal of Travel Medicine. For 20 years he was Director of the global GeoSentinel Surveillance Network which he co-founded and which maintains the largest database of ill travelers available. He also directs the Gorgas Course in Clinical Tropical Medicine given annually in Peru. He is a co-author of the IDSA Clinical Practice Guidelines on Travel Medicine. His research focuses on clinical tropical medicine and immuno-parasitology, including the development of surveillance networks to characterize infectious disease morbidity in travelers and migrants. He is funded by industry, government and multinational corporations for emerging infections, risk mitigation, and medical facilities preparedness. He was a Member of the VA Merit Review Infectious Diseases Study Section (1997-2000), Chair of the Advisory Panel on Parasitic Diseases of the US Pharmacopeia (1995-2000), and a Councilor of the American Society of Tropical Medicine and Hygiene (1998-2002). Funded research projects have been completed in India, Guatemala, Ghana, Brazil, and Peru in addition to the 24 countries where GeoSentinel sites have been established.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Tafenoquine and g6pd: A primer for clinicians 2019
    2019 Tafenoquine: Integrating a new drug for malaria prophylaxis into travel medicine practice 2019
    2018 Updated Zika virus recommendations are needed 2018
    2017 Response to "selection bias" 2017
    2017 Surveillance report of Zika virus among Canadian travellers returning from the Americas 2017
    2017 Underestimate of annual malaria imports to Canada 2017
    2016 The authors reply 2016
    2016 Medical Considerations before International Travel. 2016
    2016 Should testing of donors be restricted to active Zika virus areas? 2016
    2016 Illness in Canadian travellers and migrants from Brazil: CanTravNet surveillance data, 2013-2016. 2016
    2016 Medical considerations before international travel 2016
    2016 Malaria in travellers returning or migrating to Canada: surveillance report from CanTravNet surveillance data, 2004-2014. 2016
    2016 Re-born in the USA: Another cholera vaccine for travellers 2016
    2016 Zika virus and microcephaly: Why is this situation a PHEIC? 2016
    2015 Dermatoses among returned Canadian travellers and immigrants: surveillance report based on CanTravNet data, 2009-2012. 2015
    2015 Imminent Departures: Rapid Vaccination Strategies Designed to Induce Short-Term Immunogenicity for the Trip at Hand 2015
    2014 Travel-acquired infections in Canada: CanTravNet 2011-2012. 2014
    2014 Travel-acquired infections and illnesses in canadians: Surveillance report from CanTravNet surveillance data, 2009-2011 2014
    2013 Detection on four continents of dengue fever cases related to an ongoing outbreak in Luanda, Angola, March to May 2013. 2013
    2013 Surveillance for travel-related disease--GeoSentinel Surveillance System, United States, 1997-2011. 2013
    2013 GeoSentinel surveillance of illness in returned travelers, 2007-2011 2013
    2013 Travel-associated illness trends and clusters, 2000-2010 2013
    2013 International travelers as sentinels for sustained influenza transmission during the 2009 influenza A(H1N1)pdm09 pandemic 2013
    2013 Acute and potentially life-threatening tropical diseases in western travelers - A GeoSentinel multicenter study, 1996-2011 2013
    2013 Detection on four continents of dengue fever cases related to an ongoing outbreak in Luanda, Angola, March to May 2013 2013
    2013 Surveillance for travel-related disease - GeoSentinel surveillance system, United States, 1997-2011 2013
    2012 Expatriates ill after travel: Results from the Geosentinel Surveillance Network 2012
    2012 Ongoing outbreak of an acute muscular Sarcocystis-like illness among travellers returning from Tioman Island, Malaysia, 2011-2012 2012
    2012 Notes from the field: Acute muscular sarcocystosis among returning travelers-Tioman island, Malaysia, 2011 2012
    2012 Characteristics and spectrum of disease among ill returned travelers from pre- and post-earthquake Haiti: The geosentinel experience 2012
    2010 Sex and gender differences in travel-associated disease 2010
    2010 Short report: Health risks in travelers to South Africa: The geosentinel experience and implications for the 2010 FIFA World Cup 2010
    2010 Travel medicine, a speciality on the move 2010
    2009 Globally mobile populations and the spread of emerging pathogens 2009
    2009 Global health surveillance and travelers' health 2009
    2009 Japanese encephalitis: Is there a need for a novel vaccine? 2009
    2009 Expert opinion on vaccination of travelers against Japanese encephalitis 2009
    2009 Imported human African trypanosomiasis in Europe, 2005-2009. 2009
    2008 The author replies 2008
    2008 Characteristics of schistosomiasis in travelers reported to the GeoSentinel Surveillance Network 1997-2008 2008
    2008 Should health-care providers in the United States have access to influenza vaccines formulated for the southern hemisphere? 2008
    2008 Malaria prevention in short-term travelers 2008
    2008 A comparative analysis of methodological approaches used for estimating risk in travel medicine 2008
    2008 Gastrointestinal infection among international travelers globally 2008
    2008 Health risks in travelers to China: the GeoSentinel experience and implications for the 2008 Beijing Olympics. 2008
    2008 Seasonality, annual trends, and characteristics of dengue among Ill returned travelers, 1997-2006 2008
    2008 Short report: Health risks in travelers to China: The GeoSentinel experience and implications for the 2008 Beijing olympics 2008
    2008 The revised International Health Regulations (2005): Impact on yellow fever vaccination in clinical practice 2008
    2008 Natural history, clinicoradiologic correlates, and response to triclabendazole in acute massive fascioliasis 2008
    2008 Reply to Connor 2008
    2007 Filariasis in travelers presenting to the GeoSentinel Surveillance Network 2007
    2007 Etiology of travel-related fever 2007
    2007 Drug-free holidays: Pre-travel versus during travel malaria chemoprophylaxis 2007
    2007 Reply to Behrens et al. [4] 2007
    2006 The practice of travel medicine: Guidelines by the infectious diseases society of America 2006
    2006 Caring for the caregivers [2] 2006
    2006 The authors reply [13] 2006
    2006 Infectious risks in travelers 2006
    2006 Spectrum of disease and relation to place of exposure among ill returned travelers 2006
    2005 Prevalence and predictors of intestinal helminth infections among human immunodeficiency virus type 1-infected adults in an urban African setting 2005
    2005 Influenza: Changing approaches to prevention and treatment in travelers 2005
    2004 Transparency in publishing 2004
    2003 Confronting the New Challenge in Travel Medicine: SARS 2003
    2003 SARS - Lessons learned so far 2003
    2002 Sexual behavior of international travelers visiting Peru 2002
    2002 Educational programs to enhance medical expertise in tropical diseases: The Gorgas Course experience 1996-2001 2002
    2002 Treatment failure in intestinal strongyloidiasis: An indicator of HTLV-I infection 2002
    2001 Cashew nut dermatitis in a returned traveler 2001
    2001 TAP1 polymorphisms in several human ethnic groups: Characteristics, evolution, and genotyping strategies 2001
    2001 Effect of aggressive prolonged diethylcarbamazine therapy on circulating antigen levels in bancroftian filariasis 2001
    2001 Internet and computer-based resources for travel medicine practitioners 2001
    2001 Advanced age a risk factor for illness temporally associated with yellow fever vaccination 2001
    2001 Evaluation of the effectiveness of an international diploma course in tropical medicine 2001
    2001 Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans 2001
    1999 Emerging infectious diseases and risk to the traveler 1999
    1999 Biased TCR repertoire in infiltrating lesional T cells in human bancroftian filariasis 1999
    1999 Epidemiology and immunopathology of bancroftian filariasis 1999
    1999 GeoSentinel: The global emerging infections sentinel network of the International Society of Travel Medicine 1999
    1999 Strongyloides stercoralis hyperinfection associated with human T cell lymphotropic virus type-1 infection in Peru 1999
    1998 Immune dynamics in the pathogenesis of human lymphatic filariasis 1998
    1998 Differences in the Frequency of Cytokine-Producing Cells in Antigenemic and Nonantigenemic Individuals with Bancroftian Filariasis 1998
    1998 Keeping current. Travel medicine resources available on the Internet. 1998
    1998 Preface 1998
    1997 Field trial of a rapid card test for Wuchereria bancrofti 1997
    1997 Rapid Internet Survey: An Effective New Research Tool in Travel Medicine. 1997
    1997 T-lymphocytes from individuals with filarial inflammatory disease have increased transendothelial migration in vitro 1997
    1996 Very late antigen-4/vascular cell adhesion molecule-1 (VLA-4/VCAM-1) pathway is involved in the transendothelial migration of Lymphocytes in Bancroftian Filariasis 1996
    1996 Immunoregulation in onchocerciasis: Persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigen 1996
    1996 The presence or absence of active infection, not clinical status, is most closely associated with cytokine responses in lymphatic filariasis 1996
    1995 Predominant CD8+ infiltrate in limb biopsies of individuals with filarial lymphedema and elephantiasis 1995
    1995 Abnormal lymphatic function in presymptomatic bancroftian filariasis 1995
    1995 Lymphoscintigraphic assessment of the effect of diethylcarbamazine treatment on lymphatic damage in human bancroftian filariasis 1995
    1994 Travel medicine 1994
    1994 Cloning and characterization of a potentially protective chitinase-like recombinant antigen from Wuchereria bancrofti 1994
    1994 Lymphoscintigraphic analysis of lymphatic abnormalities in symptomatic and asymptomatic human filariasis 1994
    1994 The Onchocerca volvulus homologue of the multifunctional polypeptide protein disulfide isomerase 1994
    1994 Truly infection-free persons are rare in areas hyperendemic for african onchocerciasis 1994
    1992 Imported malaria-here to stay 1992
    1992 Rapid diagnosis of bancroftian filariasis by acridine orange staining of centrifuged parasites 1992
    1991 Experimental infection of human subjects with Strongyloides species 1991
    1991 Immunoregulation in onchocerciasis: Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapy 1991
    1990 Measles vaccine and travelers (I) 1990
    1989 Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic area 1989
    1989 Selective up-regulation of endothelial cell class I MHC expression by cytokines from patients with lymphatic filariasis 1989
    1989 The Efficacy of Ivermectin in the Chemotherapy of Gastrointestinal Helminthiasis in Humans 1989
    1988 Eggs of schistosoma mansoni stimulate endothelial cell proliferation in vitro 1988
    1988 Enhanced solubilization of immunoreactive proteins from Brugia malayi adult parasites using cetyltrimethylammonium bromide 1988
    1987 Loiasis in an expatriate American child: Diagnostic and treatment difficulties 1987
    1987 A case of laboratory acquired Leishmania donovani infection; evidence for primary lymphatic dissemination 1987

    Book

    Year Title Altmetric
    2012 Travel Medicine: Third Edition 2012
    2009 Introduction 2009
    2008 Travel Medicine 2008

    Chapter

    Year Title Altmetric
    2014 Infections in Returning Travelers.  3568-3577. 2014
    2014 Protection of Travelers.  3559-3567. 2014
    2012 Personal Security and Crime Avoidance.  463-466. 2012
    2012 Sources of Travel Medicine Information.  25-30. 2012
    2011 Detection of Infectious Diseases Using Unofficial Sources.  11-21. 2011
    2010 Travelers as Sentinels for Disease Occurrence in Destination Countries.  27-34. 2010
    2009 Advising Travelers with Specific Needs.  457-492. 2009
    2009 Select Destinations and Travel Itineraries.  242-269. 2009
    2008 Immunization of Healthy Adults.  85-120. 2008
    2008 Personal Security and Crime Avoidance.  501-504. 2008
    2008 Sources of Travel Medicine Information.  29-34. 2008
    2007 The borneo eco-challenge: GeoSentinel and rapid global sharing of disease outbreak information.  129-135. 2007
    2006 Onchocerciasis.  1176-1188. 2006

    Education And Training

  • Montreal General Hospital, Internship 1982
  • Montreal General Hospital, Residency 1984
  • Lab of Parasitic Diseases, Postdoctoral Fellowship 1989
  • National Institute of Health, Postdoctoral Fellowship 1989
  • Montreal General Hospital, Postdoctoral Fellowship 1985
  • Full Name

  • David Freedman