Michelle Fanucchi

Michelle Fanucchi
Associate Professor

Associate Scientist (C), Cystic Fibrosis Research Center , School of Medicine
Scientist (C), Global Center for Craniofacial, Oral and Dental Disorders (GC-CODED) , School of Dentistry
Associate Professor (P), Environmental Health Sciences , School of Public Health
Associate Professor (S), Mechanical Engineering , School of Engineering

Selected Publications

Academic Article

Year	Title	Altmetric
2019	The search for environmental justice: The story of north Birmingham. International Journal of Environmental Research and Public Health. 16. 2019
2018	Development of an airway mucus defect in the cystic fibrosis rat. JCI Insight. 3. 2018
2017	Effect of prenatal versus postnatal Vitamin D deficiency on pulmonary structure and function in mice. American Journal of Respiratory Cell and Molecular Biology. 56:383-392. 2017
2015	Formaldehyde exposure: During Pregnancy. MCN: The American Journal of Maternal/Child Nursing. 40:180-185. 2015
2014	Characterization of defects in ion transport and tissue development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-knockout rats. PLoS One. 9. 2014
2012	Site-specific dynamics of CD11b⁺ and CD103⁺ dendritic cell accumulations following ozone exposure 2012
2012	Administration of nitrite after chlorine gas exposure prevents lung injury: Effect of administration modality. Free Radical Biology and Medicine. 53:1431-1439. 2012
2012	Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human. Toxicological Sciences. 128:500-516. 2012
2012	Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma. Clinical and Experimental Allergy. 42:1104-1118. 2012
2012	Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats. Journal of Applied Physiology. 112:1659-1669. 2012
2012	Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation. American Journal of Respiratory Cell and Molecular Biology. 46:599-606. 2012
2011	Susceptibility to inhaled flame-generated ultrafine soot in neonatal and adult rat lungs. Toxicological Sciences. 124:472-486. 2011
2011	Increased transforming growth factor beta 1 expression mediates ozone-induced airway fibrosis in mice. Inhalation Toxicology. 23:486-494. 2011
2011	Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite 2011
2011	Postnatal episodic ozone results in persistent attenuation of pulmonary and peripheral blood responses to LPS challenge 2011
2010	Age specific responses to acute inhalation of diffusion flame soot particles: Cellular injury and the airway antioxidant response. Inhalation Toxicology. 22:70-83. 2010
2010	High resolution lung airway cast segmentation with proper topology suitable for computational fluid dynamic simulations. Computerized Medical Imaging and Graphics. 34:572-578. 2010
2010	Small particles disrupt postnatal airway development. Journal of Applied Physiology. 109:1115-1124. 2010
2010	Postnatal development of the lamina reticularis in primate airways 2010
2010	Reduction of collagen VII anchoring fibrils in the airway basement membrane zone of infant rhesus monkeys exposed to house dust mite 2010
2010	A phosholipid-apolipoprotein A-I nanoparticle containing amphotericin B as a drug delivery platform with cell membrane protective properties. International Journal of Pharmaceutics. 399:148-155. 2010
2009	Ozone Induces Pulmonary Fibrosis via a TGF-beta Signaling Pathway. Free Radical Biology and Medicine. 47. 2009
2009	Examining the impact of Ozone on lung health in a vulnerable population: A Bayesian modeling strategy. 2009
2008	Bifurcation model for characterization of pulmonary architecture 2008
2008	Pulmonary architecture in the conducting regions of six rats 2008
2008	Expiration rate drives human airway design. Journal of Theoretical Biology. 253:381-387. 2008
2008	An Automated Self-Similarity Analysis of the Pulmonary Tree of the Sprague-Dawley Rat 2008
2007	Ozone, a malady for all ages. American Journal of Respiratory and Critical Care Medicine. 176:107-108. 2007
2007	Early postnatal exposure to allergen and ozone leads to hyperinnervation of the pulmonary epithelium. Respiratory Physiology and Neurobiology. 155:55-63. 2007
2007	Asthma/Allergic Airways Disease: Does Postnatal Exposure to Environmental Toxicants Promote Airway Pathobiology?. Toxicologic Pathology. 35:97-110. 2007
2006	Asthma: A comparison of animal models using stereological methods. European Respiratory Review. 15:122-135. 2006
2006	Cyclic exposure to ozone alters distal airway development in infant rhesus monkeys 2006
2006	The basement membrane zone in asthma. Current Respiratory Medicine Reviews. 2:331-337. 2006
2006	Age-specific pulmonary cytochrome P-450 3A1 expression in postnatal and adult rats 2006
2005	Characterization of a structurally intact in situ lung model and comparison of naphthalene protein adducts generated in this model vs lung microsomes. Chemical Research in Toxicology. 18:802-813. 2005
2004	Epithelial cell distribution and abundance in rhesus monkey airways during postnatal lung growth and development. Journal of Applied Physiology. 97:2355-2363. 2004
2004	Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys. American Journal of Respiratory and Critical Care Medicine. 170:1153-1157. 2004
2004	Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys. Journal of Applied Physiology. 97:2364-2371. 2004
2004	Increased vulnerability of neonatal rats and mice to 1-nitronaphthalene- induced pulmonary injury. Toxicology and Applied Pharmacology. 201:53-65. 2004
2004	Smooth muscle hypertrophy in distal airways of sensitized infant rhesus monkeys exposed to house dust mite allergen. Clinical and Experimental Allergy. 34:1627-1633. 2004
2004	The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery. Clinical and Experimental Allergy. 34:1131-1136. 2004
2004	Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque. Journal of Pharmacology and Experimental Therapeutics. 309:127-136. 2004
2004	Postnatal remodeling of the neural components of the epithelial-mesenchymal trophic unit in the proximal airways of infant rhesus monkeys exposed to ozone and allergen.. Toxicology and Applied Pharmacology. 194:211-220. 2004
2004	Assessing gene expression in lung subcompartments utilizing in situ RNA preservation. Toxicological Sciences. 77:135-141. 2004
2004	Gene Expression Analysis in response to lung toxicants I. sequencing and microarray development. American Journal of Respiratory Cell and Molecular Biology. 30:296-310. 2004
2003	Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen 2003
2003	Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen. 2003
2003	Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys. Toxicology and Applied Pharmacology. 191:74-85. 2003
2003	Detection of viral infection in the respiratory tract of virus antibody free mice: Advantages of high-resolution imaging for respiratory toxicology. Toxicology and Applied Pharmacology. 190:286-293. 2003
2003	The effect of house dust mite aeroallergen and air pollutant exposures during infancy.. Chest. 123:434S. 2003
2002	Fibroblast growth factor-2 during postnatal development of the tracheal basement membrane zone 2002
2002	Fibroblast growth factor-2 during postnatal development of the tracheal basement membrane zone. 2002
2002	Fibroblast growth factor-2 in remodeling of the developing basement membrane zone in the trachea of infant rhesus monkeys sensitized and challenged with allergen. Laboratory Investigation. 82:1747-1754. 2002
2001	Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae). American Journal of Pathology. 158:333-341. 2001
2001	Cellular and molecular characteristics of basal cells in airway epithelium. Experimental Lung Research. 27:401-415. 2001
2001	Early events in naphthalene-induced acute Clara cell toxicity II. Comparison of glutathione depletion and histopathology by airway location. American Journal of Respiratory Cell and Molecular Biology. 24:272-281. 2001
2000	Development of phase II xenobiotic metabolizing enzymes in differentiating murine Clara cells. Toxicology and Applied Pharmacology. 168:253-267. 2000
2000	Do urban environmental pollutants exacerbate childhood lung diseases?. Environmental Health Perspectives. 108. 2000
2000	Three-dimensional organization of the lamina reticularis in the rat tracheal basement membrane zone. American Journal of Respiratory Cell and Molecular Biology. 22:393-397. 2000
1999	In vitro culture of microdissected rat nasal airway tissues. American Journal of Respiratory Cell and Molecular Biology. 20:1274-1285. 1999
1999	The attenuated fibroblast sheath of the respiratory tract epithelial-mesenchymal trophic unit. American Journal of Respiratory Cell and Molecular Biology. 21:655-657. 1999
1998	Endotoxin potentiates ozone-induced mucous cell metaplasia in rat nasal epithelium. Toxicology and Applied Pharmacology. 152:1-9. 1998
1997	Naphthalene cytotoxicity of differentiating Clara cells in neonatal mice. Toxicology and Applied Pharmacology. 144:96-104. 1997
1997	Pulmonary Cytochrome P450 Monooxygenase and Clara Cell Differentiation in Mice. American Journal of Respiratory Cell and Molecular Biology. 17:302-314. 1997
1993	Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits. Journal of Pharmacology and Experimental Therapeutics. 269:867-880. 1993
1993	Toxicokinetics and metabolism of aniline and 4-chloroaniline in medaka (oryzias latipes). Toxicology and Applied Pharmacology. 118:205-214. 1993
1991	Hepatic microsomal n-hydroxylation of aniline and 4-chloroaniline by rainbow trout (onchorhyncus mykiss) 1991

Chapter

Year	Title	Altmetric
2016	Drinking Water and Sanitation. 350-360. 2016
2014	Pulmonary Developmental Responses to Toxicants 2014
2014	Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems. 223-231. 2014
2014	Environmental Toxicants and Lung Development in Experimental Models. 439-446. 2014
2014	Age-Specific Differences in Pulmonary Cellular Injury and Mitochondrial Damage. 177-214. 2014
2014	Development of Airway Epithlieum 2014
2010	Pulmonary Developmental Responses to Toxicants. 199-221. 2010
2009	Primate Models of Allergic Asthma. 1185-1201. 2009
2008	Chronic Airway Disease in Nonhuman Primates 2008
2004	Development of Airway Epithelium. 13-32. 2004
2004	Environmental Toxicants and Lung Development in Experimental Models. 345-351. 2004
2003	Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems. 117-185. 2003
1997	Development of Airways 1997
1997	Developmental Responses to Lung Toxicants 1997