Positions

Research Overview

  • Molecular and Genetic Epidemiology of Immune-Mediated Clinical Phenotypes - The research conducted in Dr. Brown’s laboratory is mainly targeted to advance the understanding of aberrant immune function common to inflammatory-mediated chronic diseases, such as select autoimmune diseases as well as multiple myeloma and related precursor states, each with underlying B cell pathology. Within this purview, she uses a multidisciplinary functional genomics approach to explore pathways involved in chronic immune perturbation, inflammation as modifiers of disease, and B cell homeostasis. The objective of this research is to identify and validate molecular biomarkers, which may be used to target high-risk populations to improve disease surveillance and modify therapeutic intervention leading to significant reductions in morbidity and mortality associated with advanced stage disease.

    Keywords - multiple myeloma, autoimmune, lupus, genetics, genomics, epidemiology
  • Principal Investigator On

  • Characterization of the Lupus Nephritis microRNAome  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2018 - 2023
  • Association of Genetic and Autoantibody Signatures with SLE Clinical Course  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2014 - 2021
  • Molecular Characterization of Myeloma and Related Asymptomatic Precursor States  awarded by National Cancer Institute/NIH/DHHS 2014 - 2021
  • Comprehensive Cancer Center Core Support Grant - Cancer Control and Population Sciences Program  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Comprehensive Cancer Center Core Support Grant - Cancer Control and Population Sciences Program  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • A Genome-Wide Methylation Study of Multiple Myeloma  awarded by HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY 2018 - 2019
  • Comprehensive Cancer Center Core Support Grant - Cancer Control and Population Sciences Program  awarded by National Cancer Institute/NIH/DHHS 2017 - 2019
  • The Role of Exosome Heparanase and miRNAs as Biomarkers for Myeloma  awarded by National Cancer Institute/NIH/DHHS 2014 - 2018
  • Comprehensive Cancer Center Core Support Grant - Cancer Control and Population Sciences Program  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • A Genome-Wide Methylation Study of Epigenetic Contributions to Multiple Myeloma  awarded by National Cancer Institute/NIH/DHHS 2011 - 2015
  • A Genome Wide Admixture Scan of Multiple Myeloma in African-Americans  awarded by University of Southern California 2010 - 2013
  • Program Project in the Genetics of SLE - Project 4 (A Genetic Risk Profile on Longitudinal SLE Cohorts)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2009 - 2013
  • Rheumatic Diseases Core Center: Pilot Project - P & F 3  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2008 - 2010
  • Investigator On

  • Heparanase In Tumor Progression, Metastasis and Chemoresistance  awarded by National Cancer Institute/NIH/DHHS 2017 - 2022
  • Understanding the Immune Microenvironment of Light Chain (AL) Amyloidosis  awarded by Amyloidosis Foundation 2020 - 2021
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Heparanase Regulation of Myeloma Metastasis: Mechanism and Therapy  awarded by National Cancer Institute/NIH/DHHS 2014 - 2020
  • UAB Multidisciplinary Clinical Research Center (P60)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2013 - 2019
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2017 - 2019
  • Inhibition of Herpes Simplex Viruses Type 2 by Tenofovir  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2012 - 2017
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • Genome-Wide Association Study in African-Americans With Rheumatoid Arthritis  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2009 - 2016
  • Active - Major Program Leader - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • HLA Region and KIR Genomics in Common Variable Immune Deficiency  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2010 - 2015
  • Genomics of Lupus  awarded by Oklahoma Medical Research Foundation (OMRF) 2009 - 2014
  • Program Project in the Genetics of SLE  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2008 - 2014
  • Rheumatic Diseases Core Center  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2008 - 2012
  • Teaching Activities

  • EPI610 - Prin of Epidemiologic Research (Fall Term 2014) 2014
  • EPI697 - Internship (Fall Term 2014) 2014
  • EPI698 - Directed Research (Fall Term 2014) 2014
  • EPI798 - Doctoral Directed Research (Fall Term 2014) 2014
  • EPI798 - Doctoral Directed Research (Summer Term 2014) 2014
  • EPI699 - Project Research (Spring Term 2014) 2014
  • EPI699 - Project Research (Fall Term 2013) 2013
  • EPI798 - Doctoral Directed Research (Fall Term 2013) 2013
  • EPI788 - Prin/Meth Molecular Epidem (Summer Term 2013) 2013
  • EPI798 - Doctoral Directed Research (Summer Term 2013) 2013
  • EPI697 - Internship (Summer Term 2013) 2013
  • EPI699 - Project Research (Summer Term 2013) 2013
  • EPI699 - Project Research (Spring Term 2013) 2013
  • EPI798 - Doctoral Directed Research (Spring Term 2013) 2013
  • EPI799 - Dissertation Research (Spring Term 2013) 2013
  • EPI698 - Directed Research (Fall Term 2012) 2012
  • EPI790 - Doctoral Seminar (Fall Term 2012) 2012
  • EPI799 - Dissertation Research (Fall Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Summer Term 2012) 2012
  • EPI799 - Dissertation Research (Summer Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Spring Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Fall Term 2011) 2011
  • EPI788 - Prin/Meth Molecular Epidem (Summer Term 2011) 2011
  • EPI798 - Doctoral Directed Research (Summer Term 2011) 2011
  • EPI697 - Internship (Spring Term 2011) 2011
  • EPI698 - Directed Research (Spring Term 2011) 2011
  • EPI699 - Project Research (Spring Term 2011) 2011
  • EPI798 - Doctoral Directed Research (Spring Term 2011) 2011
  • EPI698 - Directed Research (Fall Term 2010) 2010
  • EPI699 - Project Research (Fall Term 2010) 2010
  • EPI798 - Doctoral Directed Research (Fall Term 2010) 2010
  • EPI699 - Project Research (Summer Term 2010) 2010
  • EPI697 - Internship (Spring Term 2010) 2010
  • EPI788 - Prin/Meth Molecular Epidem (Summer Term 2009) 2009
  • EPI697 - Internship (Summer Term 2009) 2009
  • EPI798 - Doctoral Directed Research (Summer Term 2009) 2009
  • EPI695 - Epidemiology Seminar (Spring Term 2009) 2009
  • EPI697 - Internship (Spring Term 2009) 2009
  • EPI698 - Directed Research (Spring Term 2009) 2009
  • EPI795 - Epidemiology Seminar (Spring Term 2009) 2009
  • EPI695 - Epidemiology Seminar (Fall Term 2008) 2008
  • EPI795 - Epidemiology Seminar (Fall Term 2008) 2008
  • EPI788 - Prin/Meth Molecular Epidem (Summer Term 2008) 2008
  • EPI695 - Epidemiology Seminar (Spring Term 2008) 2008
  • EPI698 - Directed Research (Spring Term 2008) 2008
  • EPI795 - Epidemiology Seminar (Spring Term 2008) 2008
  • Education And Training

  • Doctor of Philosophy in Epidemiology, Johns Hopkins University 2004
  • Master of Public Health in Epidemiology, Oregon Health Sciences University 2003
  • Bachelor of Science or Mathematics in Biology, University of Oregon 1992
  • Full Name

  • Elizabeth Brown