Selected Publications

Academic Article

Year Title Altmetric
2022 Targeted exon skipping of NF1 exon 17 as a therapeutic for neurofibromatosis type I 2022
2022 Analysis of patient-specific NF1 variants leads to functional insights for Ras signaling that can impact personalized medicineHuman Mutation.  43:30-41. 2022
2022 Functional characterization and potential therapeutic avenues for variants in the NTRK2 gene causing developmental and epileptic encephalopathiesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  189:37-47. 2022
2021 Restoration of normal NF1 function with antisense morpholino treatment of recurrent pathogenic patient-specific variant c.1466a>G; p.Y489CJournal of Personalized Medicine.  11. 2021
2021 Status and Recommendations for Incorporating Biomarkers for Cutaneous Neurofibromas Into Clinical ResearchNeurology.  97:S42-S49. 2021
2020 Mutation-Directed Therapeutics for Neurofibromatosis Type I 2020
2019 ADGRL3 (LPHN3) variants predict substance use disorderTranslational Psychiatry.  9. 2019
2019 Affinity purification of NF1 protein–protein interactors identifies keratins and neurofibromin itself as binding partnersGenes.  10. 2019
2019 Multi-Omics Profiling for NF1 Target Discovery in Neurofibromin (NF1) Deficient CellsProteomics.  19. 2019
2018 Exhaustive non-synonymous variants functionality prediction enables high resolution characterization of the neurofibromin architectureEBioMedicine.  36:508-516. 2018
2018 Neurofibromin (NF1) genetic variant structure–function analyses using a full-length mouse cDNAHuman Mutation.  39:816-821. 2018
2017 Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13Cell.  170:249-259.e25. 2017
2016 Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addictionMolecular Genetics and Genomic Medicine.  4:322-343. 2016
2015 Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic responseHuman Molecular Genetics.  24:6515-6529. 2015
2015 High-Throughput Differentiation and Screening of a Library of Mutant Stem Cell Clones Defines New Host-Based Genes Involved in Rabies Virus InfectionStem Cells.  33:2509-2522. 2015
2015 Functional genomics screening utilizing mutant mouse embryonic stem cells identifies novel radiation-response genesPLoS One.  10. 2015
2015 Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of in Utero Exposure to Environmental Pollutants in a Mouse Model 2015
2013 XTryptophan biosynthesis protects mycobacteria from CD4 T-Cell-mediated KillingCell.  155. 2013
2012 Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addictionBrain Research.  1463:85-92. 2012
2011 Screening of human LPHN3 for variants with a potential impact on ADHD susceptibilityAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  156:11-18. 2011
2010 A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medicationMolecular Psychiatry.  15:1053-1066. 2010
2010 The search for biomarkers for attention deficit/ hyperactivity disorderDrug news & perspectives.  23:438-449. 2010
2009 Polymorphisms in the neural nicotinic acetylcholine receptor α4 subunit (CHRNA4) are associated with ADHD in a genetic isolate. 2009
2009 Folate Transport and Folate Responsive Developmental Disorders.Pteridines.  20:156-162. 2009
2008 Review: Genetics of attention deficit/hyperactivity disorderJournal of Pediatric Psychology.  33:1085-1099. 2008
2008 Locus homogeneity between syndactyly type 1A and craniosynostosis Philadelphia type?American Journal of Medical Genetics Part A.  146:2308-2311. 2008
2008 Additional EFNB1 mutations in craniofrontonasal syndromeAmerican Journal of Medical Genetics Part A.  146:2008-2012. 2008
2007 Attention-Deficit/Hyperactivity Disorder and Comorbid Disruptive Behavior Disorders: Evidence of Pleiotropy and New Susceptibility LociBiological Psychiatry.  61:1329-1339. 2007
2006 Increased prevalence of ADHD in Turner syndrome with no evidence of imprinting effectsJournal of Pediatric Psychology.  31:945-955. 2006
2005 Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiationGenes and Development.  19:2412-2417. 2005
2004 Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cellsCancer Research.  64:6874-6882. 2004
2003 The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is require for inner ear hair cell differentiation and survival 2003
2000 Isolation and preliminary characterization of the human and mouse homologues of the bacterial cell cycle gene EraGenomics.  67:78-82. 2000
2000 ARP3β, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells 2000
2000 Mutations in HoloprosencephalyHuman Mutation.  16:99-108. 2000
1999 Mutations in the homeodomain of the human SIX3 gene cause holoprosencephalyNature Genetics.  22:196-198. 1999
1999 Molecular mechanisms of holoprosencephalyMolecular Genetics and Metabolism.  68:126-138. 1999
1997 Genomic structure, sequence, and mapping of human FGF8 with no evidence for its role in craniosynostosis/limb defect syndromes.American Journal of Medical Genetics Part A.  72:354-362. 1997
1997 A novel phenotypic pattern in X-linked inheritance: Craniofrontonasal syndrome maps to Xp22Human Molecular Genetics.  6:1937-1941. 1997
1997 Cytogenetic rearrangements involving the loss of the Sonic Hedgehog gene at 7q36 cause holoprosencephaly.Human Genetics.  100:172-181. 1997
1996 Comparison of polymerase chain reaction and microbiological culture for detection of salmonellae in equine feces and environmental samplesAmerican Journal of Veterinary Research.  57:780-786. 1996
1996 Molecular characterization of breakpoints in patients with holoprosencephaly and definition of the HPE2 critical region 2p21.Human Molecular Genetics.  5:223-229. 1996
1995 Detection of Salmonella enteritidis in equine feces using the polymerase chain reaction and genus-specific oligonucleotide primersJournal of Veterinary Diagnostic Investigation.  7:219-222. 1995
1994 Comparison of the polymerase chain reaction using genus-specific oligonucleotide primers and microbiologic culture for the detection of Salmonella in drag-swabs from poultry houses.Poultry Science.  73:1276-1281. 1994
1994 Detection of Salmonella enteritidis in feces from poultry using booster polymerase chain reaction and oligonucleotide primers specific for all members of the genus Salmonella.Poultry Science.  73:354-357. 1994
1994 Genus-specific detection of salmonellae in equine feces by use of the polymerase chain reaction.American Journal of Veterinary Research.  55:1049-1054. 1994
1994 Mapping the bovine homolog of the human cystic fibrosis geneJournal of Heredity.  85:490-492. 1994


Year Title Altmetric
2009 Folate-related birth defects: Embryonic consequences of abnormal folate transport and metabolism.  155-178. 2009
2002 SIX genes 2002

Education And Training

  • Doctor of Philosophy in Cell / Cellular and Molecular Biology, University of Pennsylvania 1999
  • Full Name

  • Deeann Wallis