Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Tissue-Resident Macrophages Promote Renal Cystic Disease 2019
2019 KSRP modulates melanoma growth and efficacy of vemurafenib 2019
2019 Multi-Omics Profiling for NF1 Target Discovery in Neurofibromin (NF1) Deficient Cells 2019
2019 Podocyte-specific expression of cre recombinase promotes glomerular basement membrane thickening 2019
2019 Single-cell RNA sequencing identifies candidate renal resident macrophage gene expression signatures across species 2019
2019 Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure 2019
2019 Non-obstructive vas deferens and epididymis loss in cystic fibrosis rats 2019
2019 Resident macrophages reprogram toward a developmental state after acute kidney injury 2019
2018 Biochemical and epigenetic insights into L-2-hydroxyglutarate, a potential therapeutic target in renal cancer 2018
2018 Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells 2018
2018 New microbe genomic variants in patients fecal community following surgical disruption of the upper human gastrointestinal tract 2018
2018 PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells 2018
2018 Differential and overlapping effects of 20,23(OH)2 D3 and 1,25(OH)2 D3 on gene expression in human epidermal keratinocytes: Identification of AHR as an alternative receptor for 20,23(OH)2 D3 2018
2018 Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance 2018
2018 Muscle microRNA signatures as biomarkers of disease progression in amyotrophic lateral sclerosis 2018
2018 Gene-expression analysis identifies IGFBP2 dysregulation in dental pulp cells from Human Cleidocranial dysplasia 2018
2018 Molecular response to neoadjuvant chemotherapy in high-grade serous ovarian carcinoma 2018
2018 Cell-specific deletion of PGC-1α from medium spiny neurons causes transcriptional alterations and age-related motor impairment 2018
2018 High-Throughput Tabular Data Processor – Platform independent graphical tool for processing large data sets 2018
2018 β-D-N 4 -Hydroxycytidine is a potent anti-alphavirus compound that induces a high level of mutations in the viral genome 2018
2017 Identification of donor microbe species that colonize and persist long term in the recipient after fecal transplant for recurrent Clostridium difficile 2017
2017 The Human Blood-Nerve Barrier Transcriptome 2017
2017 Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors 2017
2017 Identification of transcriptome signature for myocardial reductive stress 2017
2017 CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs 2017
2017 Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing 2017
2017 HuR promotes the molecular signature and phenotype of activated microglia: Implications for amyotrophic lateral sclerosis and other neurodegenerative diseases 2017
2017 Erratum: Author Correction: Identification of donor microbe species that colonize and persist long term in the recipient after fecal transplant for recurrent Clostridium difficile. 2017
2017 Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets 2017
2017 RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome 2017
2016 Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis 2016
2016 TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling 2016
2016 Allelic series of Huntington's disease knock-in mice reveals expression discorrelates 2016
2016 The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 2016
2016 Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder-macrophage-dependent control of acute urinary tract infection 2016
2016 Colonization potential to reconstitute a microbe community in patients detected early after fecal microbe transplant for recurrent C. difficile 2016
2016 Burkholderia pseudomallei capsule exacerbates respiratory melioidosis but does not afford protection against antimicrobial signaling or bacterial killing in human olfactory ensheathing cells 2016
2016 Somatic mutations modulate autoantibodies against galactose-deficient IgA1 in IgA nephropathy 2016
2015 Alterations in gene expression and DNA methylation during murine and human lung alveolar septation 2015
2015 Analysis of the Human Proteome in Subcutaneous and Visceral Fat Depots in Diabetic and Non-diabetic Patients with Morbid Obesity. 2015
2015 Bioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4F 2015
2015 Hypomagnesemia due to two novel TRPM6 mutations 2015
2015 Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus 2015
2015 Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction 2015
2014 Differential gene expression landscape of co-existing cervical pre-cancer lesions using RNA-seq 2014
2014 Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas 2014
2014 Getting started with microbiome analysis: Sample acquisition to bioinformatics 2014
2013 Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis 2013
2013 WNT5A Inhibits Metastasis and Alters Splicing of Cd44 in Breast Cancer Cells 2013
2012 Regulation of pattern recognition receptors by the apolipoprotein A-I mimetic peptide 4F 2012
2012 Altered DNA methylation profile in idiopathic pulmonary fibrosis 2012
2012 Sodium nitrite protects against kidney injury induced by brain death and improves post-transplant function 2012
2011 The Unfolded Protein Response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes 2011
2011 Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: A report from the Children's Oncology Group 2011
2010 Abundant lipid and protein components of drusen 2010
2010 Conservation of structure and protein-protein interactions mediated by the secreted mycobacterial proteins EsxA, EsxB, and EspA 2010
2009 Mycobacterium tuberculosis WhiB3 Maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response 2009
2008 Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon 2008
2000 High color-vision sensitivity in macaque and humans 2000

Investigator On

  • Epitranscriptomic Mapping of Novel N6-Adenosine-based RNA Methylation in MDD Brain  awarded by National Institute of Mental Health/NIH/DHHS 2019 - 2024
  • Center for Clinical and Translational Science (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS 2019 - 2024
  • Mechanism of Ultraviolet Radiation Induced Immune Tolerance  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2018 - 2023
  • Mechanism of Action and Function of Novel Secosteroid 20(OH)D3 in the Skin  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2018 - 2023
  • Significance of Metabolic Activation of Lumisterol in the Skin  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2017 - 2022
  • Histone H4 Lysine16 Acetylation in Aging and Lung Fibrosis  awarded by National Institute on Aging/NIH/DHHS 2016 - 2021
  • Cervical Cancer Derived Xenografts (PDX) and Organoid Raft Cultures to Evaluate Pathway Specific Therapeutic Agents.  awarded by National Cancer Institute/NIH/DHHS 2019 - 2020
  • Canine Immuno Neurotherapeutics  awarded by National Cancer Institute/NIH/DHHS 2017 - 2020
  • Transcriptional Regulation of Metabolism in Neurons  awarded by SOUTHERN RESEARCH INSTITUTE 2017 - 2020
  • Network Medicine Approaches to Cachexia in COPD  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2017 - 2020
  • Genetic Prediction for Treatment Resistance in Kawasaki Disease  awarded by SEATTLE CHILDREN'S RESEARCH INSTITUTE 2018 - 2019
  • Chromatin Remodeling Mechanisms of Gene Transcription in Memory  awarded by National Institute of Mental Health/NIH/DHHS 2012 - 2018
  • Transcriptional Regulation of Metabolism in Neurons  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2017
  • DHA Mechanisms in Obesity-Mediated Cardiac Remodeling Post-Myocardial Infarction  awarded by NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH/NIH/DHHS 2013 - 2016
  • Completed - Comprehensive Genomics Shared Facility - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Completed - Comprehensive Cancer Center Core Support Grant - Micro Array SF  awarded by National Cancer Institute/NIH/DHHS 2011 - 2013
  • Full Name

  • David Crossman