• My research has focused on the metabolism of Nicotinamide Adenine Dinucleotide (NAD), the bioactive form of the vitamin niacin, and the roles that NAD-utilizing enzymes and NAD-derived molecules play in modulating cellular life/death decisions and inflammatory responses following oxidative stress. My interests are in basic and translational research aimed at (i) validating NAD metabolism as a therapeutic target, and (ii) discovering new therapies for the treatment of diseases as diverse as cancer, chronic obstructive pulmonary disease (COPD), interstitial pulmonary fibrosis (IPF), influenza, acute respiratory distress syndrome (ARDS), Alzheimer’s Disease, and schistosomiasis.
  • Full Name

  • Davide Botta