Selected Publications

Academic Article

Year Title Altmetric
2016 Discovery of clinically approved agents that promote suppression of cystic fibrosis transmembrane conductance regulator nonsense mutations.  American Journal of Respiratory and Critical Care Medicine.  194:1092-1103. 2016
2014 Characterization of defects in ion transport and tissue development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-knockout rats.  PLoS ONE.  9. 2014
2014 Long-term nonsense suppression therapy moderates MPS I-H disease progression.  Molecular Genetics and Metabolism.  111:374-381. 2014
2014 Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and are enhanced by ivacaftor.  American Journal of Respiratory Cell and Molecular Biology.  50:805-816. 2014
2011 IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.  Diabetes.  60:3223-3234. 2011
2009 A vital role for Interleukin-21 in the control of a chronic viral infection.  Science.  324:1572-1576. 2009
2009 Poly-L-aspartic acid enhances and prolongs gentamicin-mediated suppression of the CFTR-G542X mutation in a cystic fibrosis Mouse model.  Journal of Biological Chemistry.  284:6885-6892. 2009
2008 Distinct eRF3 Requirements Suggest Alternate eRF1 Conformations Mediate Peptide Release during Eukaryotic Translation Termination.  Molecular Cell.  30:599-609. 2008
2008 PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model 2008
2006 Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model 2006
2004 Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae.  RNA.  10:691-703. 2004
2002 Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene 2002
2002 Synergistic cytotoxic effect between serine-threonine phosphatase inhibitors and 5-fluorouracil: A novel concept for modulation of cytotoxic effect.  Cancer Chemotherapy and Pharmacology.  49:111-118. 2002

Education And Training

  • Doctor of Philosophy Level Degree in Biochemistry, Chiba University 1997

    • Full Name

  • Ming Du