Positions

Selected Publications

Academic Article

Year Title Altmetric
2010 Dietary flavonoid quercetin stimulates vasorelaxation in aortic vesselsFree Radical Biology and Medicine.  49:339-347. 2010
2009 Alcohol in moderation, cardioprotection, and neuroprotection: Epidemiological considerations and mechanistic studiesAlcoholism: Clinical and Experimental Research.  33:206-219. 2009
2008 Mechanical circulatory device thrombosis: A new paradigm linking hypercoagulation and hypofibrinolysisASAIO Journal.  54:351-358. 2008
2007 Decreased hepatic ischemia-reperfusion injury by manganese-porphyrin complexesFree Radical Research.  41:127-134. 2007
2007 Pharmacokinetics of once-daily tenofovir, emtricitabine, ritonavir and fosamprenavir in HIV-infected subjectsAIDS.  21:1373-1375. 2007
2007 Mechanism by which Alcohol and Wine Polyphenols Affect Coronary Heart Disease RiskAnnals of Epidemiology.  17. 2007
2005 Evidence of cardiovascular protection by moderate alcohol: Role of nitric oxideFree Radical Biology and Medicine.  39:540-548. 2005
2005 Revealing anti-inflammatory mechanisms of soy isoflavones by flow: Modulation of leukocyte-endothelial cell interactions 2005
2004 L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemiaFEBS Letters.  561:94-98. 2004
2004 Peroxynitrite Inactivates Tissue Plasminogen ActivatorAnesthesia and Analgesia.  98:1312-1317. 2004
2004 Peroxynitrite decreases hemostasis in Human plasma in vitroAnesthesia and Analgesia.  99:21-26. 2004
2002 Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitrationFree Radical Biology and Medicine.  33:1243-1249. 2002
2002 Mitochondrial function in response to cardiac ischemia-reperfusion after oral treatment with quercetinFree Radical Biology and Medicine.  32:1220-1228. 2002
2002 Iron regulates xanthine oxidase activity in the lung 2002
2001 Antioxidant mechanisms of isoflavones in lipid systems: Paradoxical effects of peroxyl radical scavengingFree Radical Biology and Medicine.  31:1570-1581. 2001
2001 Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid. 2001
2001 Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid 2001
2001 Enhanced antioxidant activity after chlorination of quercetin by hypochlorous acidAlcoholism: Clinical and Experimental Research.  25:434-443. 2001
2001 Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolicsBioFactors.  15:79-81. 2001
2000 Evaluation of low-dose endotoxin administration during pregnancy as a model of preeclampsiaAnesthesiology.  93:1446-1455. 2000
1999 Preserving brain function during neonatal asphyxiaClinics in Perinatology.  26:733-747. 1999
1998 Hypoxia-reoxygenation is as damaging as ischemia-reperfusion in the rat liverCritical Care Medicine.  26:1089-1095. 1998
1998 Endothelial injury from a circulating mediator following rat liver ischemiaFree Radical Biology and Medicine.  24:427-434. 1998
1998 Upregulation of xanthine oxidase by lipopolysaccharide, interleukin-1, and hypoxia: Role in acute lung injuryAmerican Journal of Respiratory and Critical Care Medicine.  158:299-305. 1998
1997 Halothane and xanthine oxidase increase hepatocellular enzyme release and circulating lactate after ischemia - Reperfusion in rabbitsAnesthesiology.  87:908-917. 1997
1997 Hextend® (hetastarch solution) decreases multiple organ injury and xanthine oxidase release after hepatoenteric ischemia-reperfusion in rabbitsCritical Care Medicine.  25:1565-1574. 1997
1997 Free and protein-associated nitrotyrosine formation following rat liver preservation and transplantationArchives of Biochemistry and Biophysics.  342:282-288. 1997
1997 Xanthine oxidase mediates myocardial injury after hepatoenteric ischemia-reperfusionCritical Care Medicine.  25:1044-1050. 1997
1996 Gastric intramucosal pH and multiple organ injury: Impact of ischemia- reperfusion and xanthine oxidaseCritical Care Medicine.  24:1339-1344. 1996
1996 Lung injury after hepatoenteric ischemia-reperfusion: Role of xanthine oxidaseAmerican Journal of Respiratory and Critical Care Medicine.  154:1364-1369. 1996
1995 Liver ischemia-reperfusion increases pulmonary permeability in rat: Role of circulating xanthine oxidase 1995
1993 Role of angiotensin and adrenoceptors in hemodynamic response to aortic cross-clampingAmerican Journal of Physiology.  264. 1993
1993 Role of angiotensin and adrenoceptors in hemodynamic response to aortic cross-clamping.American Journal of Physiology.  264:H14-H20. 1993
1993 Xanthine oxidase activity in the circulation of rats following hemorrhagic shockFree Radical Biology and Medicine.  15:407-414. 1993
1992 Haemodynamic changes and oxygen uptake during crossclamping of the thoracic aorta in dexmedetomidine pretreated dogs 1992
1992 Inhibition of xanthine oxidase by uric acid and its influence on superoxide radical production 1992
1992 Responses of vascular endothelial oxidant metabolism to lipopolysaccharide and tumor necrosis factor-αArchives of Biochemistry and Biophysics.  294:686-694. 1992
1991 Role of xanthine dehydrogenase and oxidase in focal cerebral ischemic injury to rat.American Journal of Physiology.  261:H2051-H2057. 1991
1991 H1 and H2 receptor antagonists and hepatic oxygen supply-demand relationship in pigs 1991
1991 Role of xanthine dehydrogenase and oxidase in focal cerebral ischemic injury to ratAmerican Journal of Physiology.  261. 1991
1990 Circulating xanthine oxidase: potential mediator of ischemic injury.American Journal of Physiology.  258:G564-G570. 1990
1990 Circulating xanthine oxidase: Potential mediator of ischemic injuryAmerican Journal of Physiology.  258. 1990
1990 Dopamine and hepatic oxygen supply - Demand relationshipCanadian Journal of Physiology and Pharmacology.  68:1165-1169. 1990
1990 Hepatic circulation and oxygen supply-uptake relationships after hepatic ischemic insult during anesthesia with volatile anesthetics and fentanyl in miniature pigsAnesthesia and Analgesia.  70:53-62. 1990
1990 Hepatic oxygen supply-uptake relationship and metabolism during anesthesia in miniature pigsAnesthesiology.  72:902-910. 1990
1990 Hypothermia, hepatic oxygen supply-demand, and ischemia-reperfusion injury in pigsAmerican Journal of Physiology.  258. 1990
1989 A sensitive fluorometric assay for measuring xanthine dehydrogenase and oxidase in tissuesFree Radical Biology and Medicine.  6:607-615. 1989
1989 Oxygen radicals: Mediators of gastrointestinal pathophysiologyGut.  30:293-298. 1989
1988 Allopurinol does not enhance antioxidant properties of extracellular fluidAmerican Journal of Physiology.  255. 1988
1988 Conversion of xanthine dehydrogenase to oxidase in ischemic rat intestine: A reevaluationAmerican Journal of Physiology.  254. 1988
1988 Ischemia‐reperfusion injury: A radical viewHepatology.  8:680-682. 1988
1987 Glucagon increases hepatic oxygen supply-demand ratio in pigs 1987
1986 Contributions of ischemia and reperfusion to mucosal lesion formation 1986
1986 Incarcerate free radicalsHepatology.  6:536-537. 1986
1986 Ischemia-reperfusion injury: role of oxygen-derived free radicals 1986
1986 Role of oxygen radicals in ischemia-induced lesions in the cat stomachGastroenterology.  90:362-367. 1986
1986 Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestineGastroenterology.  90:80-84. 1986
1986 Xanthine oxidase: Biochemistry, distribution and physiology 1986
1985 Physiology of the Splanchnic CirculationArchives of Internal Medicine.  145:1278-1281. 1985
1985 Relationship of blood flow and oxygen consumption to ischemic injury in the canine small intestineGastroenterology.  89:852-857. 1985
1985 Soybean trypsin inhibitor attenuates ischemic injury to the feline small intestineGastroenterology.  89:6-12. 1985
1984 Oxygen radicals: Effects on intestinal vascular permeability 1984
1983 Intestinal blood flow: Relations to function 1983
1983 Ischemia-induced vascular changes: Role of xanthine oxidase and hydroxyl radicals 1983
1982 Effects of ischemia and oxygen radicals on mucosal albumin clearance in intestine 1982
1982 Ischemic injury in the cat small intestine: Role of superoxide radicalsGastroenterology.  82:9-15. 1982

Education And Training

  • Doctor of Philosophy in Medical Basic Sciences, University of South Alabama 1983
  • Full Name

  • Dale Parks