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Colin Reily
Assistant Professor
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E-mail
creily@uab.edu
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Colin Reily
Assistant Professor
Positions
Associate Scientist (C)
,
Nephrology Research & Training Center
,
General Clinical Research Center
Assistant Professor (P)
,
Medicine - Nephrology
,
Department of Medicine
Assistant Professor (S)
,
Microbiology
,
Academic Joint Departments
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2023
Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1
.
Cellular and Molecular Immunology
.
2023
2022
Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits
.
Nature Communications
. 13.
2022
2022
Phosphatase control of cytokine-mediated overproduction of galactose-deficient IgA1, the main autoantigen in IgA nephropathy
.
Journal of Autoimmunity
. 132.
2022
2022
Cytokines and Production of Aberrantly O-Glycosylated IgA1, the Main Autoantigen in IgA Nephropathy
.
Journal of Interferon and Cytokine Research
. 42:301-315.
2022
2021
Pathogenesis of iga nephropathy: Current understanding and implications for development of disease-specific treatment
.
Journal of Clinical Medicine
. 10.
2021
2021
Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathy
.
Journal of Autoimmunity
. 118.
2021
2021
Immunoglobulin A Glycosylation and Its Role in Disease
2021
2020
Assigning immunoglobulin class from single-cell transcriptomes in IgA1-secreting versus membrane subpopulations
2020
2019
Correction: Galactose-deficient IgA1 and the corresponding IgG autoantibodies predict IgA nephropathy progression (PLoS One (2019) 14:2 (e0212254) DOI: 10.1371/journal.pone.0212254)
.
PLoS One
. 14.
2019
2019
Glycosylation in health and disease
.
Nature Reviews Nephrology
. 15:346-366.
2019
2019
Galactose-deficient IgA1 and the corresponding IgG autoantibodies predict IgA nephropathy progression
.
PLoS One
. 14.
2019
2018
Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients
2018
2017
GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway
.
PLoS Genetics
. 13.
2017
2017
Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy
.
Kidney International Reports
. 2:1194-1207.
2017
2016
Markers for the progression of IgA nephropathy
.
Journal of Nephrology
. 29:535-541.
2016
2016
The origin and activities of IgA1-containing immune complexes in IGA nephropathy
.
Frontiers in Immunology
. 7.
2016
2016
Somatic mutations modulate autoantibodies against galactose-deficient IgA1 in IgA nephropathy
.
Journal of the American Society of Nephrology
. 27:3278-3284.
2016
2016
Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic Study
.
Disease Markers
. 2016.
2016
2015
New Insights into the Pathogenesis of IgA Nephropathy.
.
Kidney Diseases
. 1:8-18.
2015
2014
Cellular Signaling and Production of Galactose-Deficient IgA1 in IgA Nephropathy, an Autoimmune Disease
.
Journal of Immunology Research
. 2014.
2014
2013
Mitochondrially targeted compounds and their impact on cellular bioenergetics
.
Redox Biology
. 1:86-93.
2013
2011
Assessing bioenergetic function in response to oxidative stress by metabolic profiling
.
Free Radical Biology and Medicine
. 51:1621-1635.
2011
2010
Prevention of diabetic nephropathy in Ins2
+/-AkitaJ
mice by the mitochondria-targeted therapy MitoQ
.
Biochemical Journal
. 432:9-19.
2010
2009
Methods for the determination and quantification of the reactive thiol proteome
.
Free Radical Biology and Medicine
. 47:675-683.
2009
Chapter
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Year
Title
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2016
Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy
. 53-68.
2016
Research
Principal Investigator On
Abnormal Cytokine Response and Autoantigen Production in IgA-Producing Subpopulations in IgA Nephropathy
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Abnormal STAT3 Signaling and Aberrant O-Glycosylation of IgA1 in IgA Nephropathy
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Investigator On
Elucidating lgA Nephropathy through Genetic Studies of lgA 1 Glycosylation
awarded by
Columbia University
Interdisciplinary Training In Kidney-Related Research
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Interdisciplinary Training in Kidney-Related Research
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Kidney Undergraduate Research Experience (KURE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
PRedOctoral Phd and MD Research Training In TEams (PROmoTE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
PRedoctoral Interdisciplinary Training in Renal Physiology and MEdIcIne (PRIME)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Pathogenic Autoantibodies with Specificity for Aberrant Glycoproteins: Assessment of a Therapeutic Target in an Autoimmune Disease
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Private Grant
awarded by
RETROPHIN, INC.
UAB Center for AIDS Research
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Background
Education And Training
Doctor of Philosophy in Pathology/Human and Animal,
University of Alabama at Birmingham
2012
Bachelor of Science or Mathematics in Biology,
Saint Olaf College
2006
Contact
Full Name
Colin
Reily