Positions

Selected Publications

Academic Article

Year Title Altmetric
2023 Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1Cellular and Molecular Immunology2023
2022 Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traitsNature Communications.  13. 2022
2022 Phosphatase control of cytokine-mediated overproduction of galactose-deficient IgA1, the main autoantigen in IgA nephropathyJournal of Autoimmunity.  132. 2022
2022 Cytokines and Production of Aberrantly O-Glycosylated IgA1, the Main Autoantigen in IgA NephropathyJournal of Interferon and Cytokine Research.  42:301-315. 2022
2021 Pathogenesis of iga nephropathy: Current understanding and implications for development of disease-specific treatmentJournal of Clinical Medicine.  10. 2021
2021 Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathyJournal of Autoimmunity.  118. 2021
2021 Immunoglobulin A Glycosylation and Its Role in Disease 2021
2020 Assigning immunoglobulin class from single-cell transcriptomes in IgA1-secreting versus membrane subpopulations 2020
2019 Correction: Galactose-deficient IgA1 and the corresponding IgG autoantibodies predict IgA nephropathy progression (PLoS One (2019) 14:2 (e0212254) DOI: 10.1371/journal.pone.0212254)PLoS One.  14. 2019
2019 Glycosylation in health and diseaseNature Reviews Nephrology.  15:346-366. 2019
2019 Galactose-deficient IgA1 and the corresponding IgG autoantibodies predict IgA nephropathy progressionPLoS One.  14. 2019
2018 Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients 2018
2017 GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathwayPLoS Genetics.  13. 2017
2017 Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA NephropathyKidney International Reports.  2:1194-1207. 2017
2016 Markers for the progression of IgA nephropathyJournal of Nephrology.  29:535-541. 2016
2016 The origin and activities of IgA1-containing immune complexes in IGA nephropathyFrontiers in Immunology.  7. 2016
2016 Somatic mutations modulate autoantibodies against galactose-deficient IgA1 in IgA nephropathyJournal of the American Society of Nephrology.  27:3278-3284. 2016
2016 Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic StudyDisease Markers.  2016. 2016
2015 New Insights into the Pathogenesis of IgA Nephropathy.Kidney Diseases.  1:8-18. 2015
2014 Cellular Signaling and Production of Galactose-Deficient IgA1 in IgA Nephropathy, an Autoimmune DiseaseJournal of Immunology Research.  2014. 2014
2013 Mitochondrially targeted compounds and their impact on cellular bioenergeticsRedox Biology.  1:86-93. 2013
2011 Assessing bioenergetic function in response to oxidative stress by metabolic profilingFree Radical Biology and Medicine.  51:1621-1635. 2011
2010 Prevention of diabetic nephropathy in Ins2+/-AkitaJ mice by the mitochondria-targeted therapy MitoQBiochemical Journal.  432:9-19. 2010
2009 Methods for the determination and quantification of the reactive thiol proteomeFree Radical Biology and Medicine.  47:675-683. 2009

Chapter

Year Title Altmetric
2016 Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy.  53-68. 2016

Education And Training

  • Doctor of Philosophy in Pathology/Human and Animal, University of Alabama at Birmingham 2012
  • Bachelor of Science or Mathematics in Biology, Saint Olaf College 2006
  • Full Name

  • Colin Reily