Positions

Overview

  • David Cooper studied medicine at Guy’s Hospital Medical School in London (now merged with King’s College London). He subsequently trained in general and cardiothoracic surgery in Cambridge and London, interrupting this training to carry out research for the PhD degree. He was present at the first heart transplant in the UK in 1968, and a member of the team that initiated the heart transplant program at Papworth Hospital in 1979. Between 1972 and 1980, he was a Fellow and Director of Studies in Medicine at Magdalene College, Cambridge.

    In 1980 he took up an appointment in cardiac surgery at Groote Schuur Hospital at the University of Cape Town where, under Professor Christiaan Barnard (who, in 1967 had carried out the world’s first heart transplant), he had responsibility for patients undergoing heart transplantation. With Winston Wicomb and Dimitri Novitzky, he developed a hypothermic perfusion device to store donor hearts, which was used clinically, and investigated the detrimental effects of brain death on donor organs before establishing thyroid hormone therapy in the management of potential organ donors.

    In 1987, he relocated to the Oklahoma Transplantation Institute in the USA where he continued to work in both the clinical and research fields. With colleagues, he identified the importance of the Gal antigen in xenotransplantation. After 17 years as a surgeon-scientist, he decided to concentrate on research, initially at the Massachusetts General Hospital/Harvard Medical School in Boston, subsequently at the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh, and now at UAB. His major interest is the xenotransplantation of organs, islets, and corneas in pig-to-nonhuman primate models, with the aim of using genetically-engineered pigs as a solution to the organ shortage for clinical transplantation.

    The Royal College of Surgeons of England appointed him to a Hunterian Professorship (1983), Arris and Gale Lectureship (1988), Amott Lectureship (2002), and awarded him the 1997 Jacksonian Prize and Medal. Professor Cooper has published more than 850 medical and scientific papers and chapters, has authored or edited 11 books, and has given more than 300 invited presentations worldwide.

    Between 1994-7, he was Honorary Secretary/Treasurer of the International Society for Heart and Lung Transplantation. He was the Founding Honorary Secretary of the International Xenotransplantation Association IXA) in 1997, its President in 1999-2001, and the Editor-in-Chief of Xenotransplantation from 2001-7. In 2009, he was elected to Honorary Membership of the IXA.

    He has also received the American Society of Transplant Surgeons (ASTS)-Roche Presidential Travel Award (2007), The Transplantation Society-Roche Award for Excellence in Translational Science (2010), the American Society of Transplantation (AST) Basic Science Established Investigator Award (2014), and The Transplantation Society’s Award for Outstanding Achievement in Transplantation (Basic Science) (2016). In 2016 he was made a Fellow of his alma mater, King’s College London.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Indicators of impending pig kidney and heart xenograft failure: Relevance to clinical organ xenotransplantation - Review articleInternational Journal of Surgery.  70:84-91. 2019
    2019 Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive RegimensTransplantation.  103:2090-2104. 2019
    2019 The potential role of 3D-bioprinting in xenotransplantationInternational Journal of Clinical and Laboratory Research.  24:547-554. 2019
    2019 A potential role of TLR2 in xenograft rejection of porcine iliac endothelial cells: An in vitro studyXenotransplantation.  26. 2019
    2019 Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review articleInternational Journal of Surgery.  69:100-107. 2019
    2019 In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic DegenerationSchizophrenia Bulletin.  108:624-635. 2019
    2019 Isolation and culture of primary aortic endothelial cells from miniature pigsJournal of Visualized Experiments.  2019. 2019
    2019 TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expressionCancer Bulletin.  17. 2019
    2019 Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejectionXenotransplantation.  26. 2019
    2019 Justification of specific genetic modifications in pigs for clinical organ xenotransplantationXenotransplantation.  26. 2019
    2019 The complex functioning of the complement system in xenotransplantationXenotransplantation.  26. 2019
    2019 The “Baby Fae” baboon heart transplant—Potential cause of rejectionXenotransplantation.  26. 2019
    2019 Evidence for the important role of inflammation in xenotransplantationJournal of inflammation.  16. 2019
    2019 Biodistribution of strontium and barium in the developing and mature skeleton of ratsJournal of Bone and Mineral Metabolism.  37:385-398. 2019
    2019 A review of pig liver xenotransplantation: Current problems and recent progressXenotransplantation.  26. 2019
    2019 Carbohydrate antigen expression and anti-pig antibodies in New World capuchin monkeys: Relevance to studies of xenotransplantationXenotransplantation.  26. 2019
    2019 Financial support for xenotransplantation researchXenotransplantation.  26. 2019
    2019 Genetically-engineered pigs as sources for clinical red blood cell transfusion: What pathobiological barriers need to be overcome?Japanese Journal of Thrombosis and Hemostasis.  35:7-17. 2019
    2019 Life-supporting porcine cardiac xenotransplantation: The Munich studyXenotransplantation.  26. 2019
    2019 Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantationXenotransplantation.  26. 2019
    2019 Experimental Pig Heart Xenotransplantation—Recent Progress and Remaining ProblemsSchizophrenia Bulletin.  107:989-992. 2019
    2019 Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ XenotransplantationLaboratory Animal Science.  69:86-94. 2019
    2019 Chronic dialysis in patients with end-stage renal disease: Relevance to kidney xenotransplantationXenotransplantation.  26. 2019
    2019 Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: A new syndrome of clinical importance?Xenotransplantation.  26. 2019
    2019 Oscar Salvatierra, Jr, MD (1935-2019)Xenotransplantation.  26:e12521. 2019
    2019 Will donor-derived neoplasia be problematic after clinical pig organ or cell xenotransplantation?Xenotransplantation.  26. 2019
    2019 The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome?Pediatric Cardiology.  40:437-444. 2019
    2019 A New fossil species of pycnomerus erichson (coleoptera: Zopheridae) from baltic amber, and a replacement name for a recent North American congenerZootaxa.  4550:565-572. 2019
    2019 A method for islet transplantation to the omentum in mouseJournal of Visualized Experiments.  2019. 2019
    2019 Circulating miRNA or circulating DNA—Potential biomarkers for organ transplant rejectionXenotransplantation.  26. 2019
    2019 Decellularization methods for developing porcine corneal xenografts and future perspectivesXenotransplantation2019
    2019 Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cellsXenotransplantation2019
    2019 Paediatric xenotransplantation clinical trials and the right to withdrawJournal of Medical Ethics2019
    2019 Selective inhibition of cyclooxygenase-2 protects porcine aortic endothelial cells from human antibody-mediated complement-dependent cytotoxicityXenotransplantation2019
    2018 B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapyTransplant Immunology.  51:12-20. 2018
    2018 Crossover artifact in X-ray focusing imaging systems: K-edge subtraction imagingNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment.  910:26-34. 2018
    2018 Perspectives on the Optimal Genetically Engineered Pig in 2018 for Initial Clinical Trials of Kidney or Heart XenotransplantationTransplantation.  102:1974-1982. 2018
    2018 Serum amyloid a as an indicator of impending xenograft failure: Experimental studiesInternational Journal of Surgery.  60:283-290. 2018
    2018 An approach to induction of tolerance to pig cardiac xenografts in neonatesXenotransplantation.  25. 2018
    2018 Skin xenotransplantation: Historical review and clinical potentialBlood Pressure -Supplement-.  44:1738-1749. 2018
    2018 Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapyJournal of Spinal Disorders and Techniques.  20:1965-1974. 2018
    2018 Physiologic aspects of pig kidney transplantation in nonhuman primatesLaboratory Animal Science.  68:332-340. 2018
    2018 The effect of growth rate on the three-dimensional orientation of vascular canals in the cortical bone of broiler chickensJournal of Anatomy.  233:531-541. 2018
    2018 Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of XenograftsInternational Journal Of Value Based Management.  66:355-364. 2018
    2018 Xenotransplantation research and the ‘International Journal of Surgery’International Journal of Surgery.  58:57-59. 2018
    2018 Porcine IL-6, IL-1β, and TNF-α regulate the expression of pro-inflammatory-related genes and tissue factor in human umbilical vein endothelial cellsXenotransplantation.  25. 2018
    2018 Franklin expedition lead exposure: New insights from high resolution confocal x-ray fluorescence imaging of skeletal microstructurePLoS ONE.  13. 2018
    2018 Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates: Recent ProgressTransplantation.  102:1050-1058. 2018
    2018 Christiaan Barnard-The surgeon who dared: The story of the first human-to-human heart transplant.Global Cardiology Science & Practice.  2018:11. 2018
    2018 Interpreting the three-dimensional orientation of vascular canals and cross-sectional geometry of cortical bone in birds and batsJournal of Anatomy.  232:931-942. 2018
    2018 20th Anniversary of IXA, 1998–2018Xenotransplantation.  25. 2018
    2018 Immune Responses of HLA Highly Sensitized and Nonsensitized Patients to Genetically Engineered Pig CellsTransplantation.  102:e195-e204. 2018
    2018 Is sensitization to pig antigens detrimental to subsequent allotransplantation?Xenotransplantation.  25. 2018
    2018 Jewish, Christian and Muslim theological perspectives about xenotransplantationXenotransplantation.  25. 2018
    2018 Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAHOperative Techniques in Orthopaedics.  72:196-205. 2018
    2018 Christiaan Barnard's views on euthanasiaGeriatric Nursing.  31:229-230. 2018
    2018 Bringing Home the Bacon: Update on the State of Kidney XenotransplantationInternational Journal of Interferon, Cytokine and Mediator Research.  45:254-259. 2018
    2018 The Sda and Cad glycan antigens and their glycosyltransferase, β1,4GalNAcT-II, in xenotransplantationXenotransplantation.  25. 2018
    2018 Xenotransplantation - The current status and prospectsClinical Gastroenterology and Hepatology.  125:5-14. 2018
    2018 Corrigendum to "The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation"Journal of Immunology Research.  2018:6343608. 2018
    2018 Expression and regulation profile of mature microRNA in the pig: Relevance to xenotransplantationIssues in Accounting Education.  2018. 2018
    2017 Christiaan Barnard's defining moment: The epic first human heart transplant performed 50 years ago by Chris Barnard is discussed by David Cooper MD who was with Barnard at Groote Schuur Hospital in Cape TownEuropean Heart Journal.  38:3400-3401. 2017
    2017 Life's defining moment: Christiaan Barnard and the first human heart transplantThe Journal of heart transplantation.  36:1273-1275. 2017
    2017 Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey ModelScientific Reports.  7. 2017
    2017 Xenotransplantation: Past, present, and futureInternational Journal of Clinical and Laboratory Research.  22:513-521. 2017
    2017 Contributions to the palaeofauna of Ptinidae (Coleptera) known from Baltic amberZootaxa.  4344:181-188. 2017
    2017 Low anti-pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient?Xenotransplantation.  24. 2017
    2017 MiscellaneousXenotransplantation.  24. 2017
    2017 Occurrence of osteon banding in adult human cortical boneHarvard International Review.  164:635-642. 2017
    2017 The forgotten French: The ‘heroic’ era of kidney transplantationJournal of Medical Biography.  25:234-239. 2017
    2017 An Investigation of Extracellular Histones in Pig-To-Baboon Organ XenotransplantationTransplantation.  101:2330-2339. 2017
    2017 Encapsulation of Human Islets Using a Biomimetic Self-Assembled Nanomatrix Gel for Protection against Cellular Inflammatory ResponsesBiochemical Engineering Journal.  3:2110-2119. 2017
    2017 David J. G. White, PhD, FRCPathXenotransplantation.  24. 2017
    2017 Regulation of Clinical Xenotransplantation-Time for a ReappraisalTransplantation.  101:1766-1769. 2017
    2017 Altered expression of eNOS, prostacyclin synthase, prostaglandin G/H synthase, and thromboxane synthase in porcine aortic endothelial cells after exposure to human serum—relevance to xenotransplantationAntimicrobial Agents and Chemotherapy.  41:798-808. 2017
    2017 Angiopoietin-1 and angiopoietin-2 protect porcine iliac endothelial cells from human antibody-mediated complement-dependent cytotoxicity through phosphatidylinositide 3-kinase/AKT pathway activationXenotransplantation.  24. 2017
    2017 Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humansPLoS ONE.  12. 2017
    2017 Financial aspects of organ procurement from deceased donors in the USA—Relevance to xenotransplantationXenotransplantation.  24. 2017
    2017 La(III) biodistribution profiles from intravenous and oral dosing of two lanthanum complexes, La(dpp)3 and La(XT), and evaluation as treatments for bone resorption disordersMetallomics.  9:902-909. 2017
    2017 Selection of Patients for Initial Clinical Trials of Solid Organ XenotransplantationTransplantation.  101:1551-1568. 2017
    2017 Skeletal Lead Burden of the British Royal Navy in Colonial AntiguaInternational Journal of Osteoarchaeology.  27:672-682. 2017
    2017 The impact of serum incubation time on IgM/IgG binding to porcine aortic endothelial cellsXenotransplantation.  24. 2017
    2017 Renal Allograft Survival in Nonhuman Primates Infused With Donor Antigen-Pulsed Autologous Regulatory Dendritic CellsAmerican Journal of Biochemistry and Biotechnology.  17:1476-1489. 2017
    2017 Evaluating differential nuclear DNA yield rates and osteocyte numbers among human bone tissue types: A synchrotron radiation micro-CT approachForensic Science International: Genetics.  28:211-218. 2017
    2017 Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant RejectionAmerican Journal of Biochemistry and Biotechnology.  17:931-943. 2017
    2017 Renal xenotransplantation: experimental progress and clinical prospectsKidney International.  91:790-796. 2017
    2017 Early clinical xenotransplantation experiences—An interview with Thomas E. Starzl, MD, PhDXenotransplantation.  24. 2017
    2017 Human IL-6, IL-17, IL-1β, and TNF-α differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial cellsXenotransplantation.  24. 2017
    2017 Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney graftsXenotransplantation.  24. 2017
    2017 Superior spatial resolution in confocal X-ray techniques using collimating channel array optics: Elemental mapping and speciation in archaeological human boneJournal of Analytical Atomic Spectrometry.  32:527-537. 2017
    2017 Therapeutic regulation of systemic inflammation in xenograft recipientsXenotransplantation.  24. 2017
    2017 Thomas E. Starzl, MD, PhD, 1926-2017Xenotransplantation.  24. 2017
    2017 Transplantation of hepatocytes from genetically engineered pigs into baboonsXenotransplantation.  24. 2017
    2017 The White House Organ SummitAmerican Journal of Biochemistry and Biotechnology.  17:576. 2017
    2017 A method for measuring the three-dimensional orientation of cortical canals with implications for comparative analysis of bone microstructure in vertebratesMicron.  92:32-38. 2017
    2017 Development of retrocorneal membrane following pig-to-monkey penetrating keratoplastyXenotransplantation.  24. 2017
    2017 Initial study of α1,3-galactosyltransferase gene-knockout/CD46 pig full-thickness corneal xenografts in rhesus monkeysXenotransplantation.  24. 2017
    2017 Klotho attenuated antibody-mediated porcine endothelial cell activation and injuryXenotransplantation.  24. 2017
    2017 Pig-to-primate islet xenotransplantation: Past, present, and futureJournal of Prosthetic Dentistry.  26:925-947. 2017
    2017 Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloningJournal of Reproduction and Development.  63:17-26. 2017
    2017 Safe use of anti-CD154 monoclonal antibody in pig islet xenotransplantation in monkeysXenotransplantation.  24. 2017
    2017 The Role of Costimulation Blockade in Solid Organ and Islet XenotransplantationJournal of Immunology Research.  2017. 2017
    2016 Spectral K-edge subtraction imaging of experimental non-radioactive barium uptake in bonePhysica Medica.  32:1765-1770. 2016
    2016 Progress in Clinical Encapsulated Islet XenotransplantationTransplantation.  100:2301-2308. 2016
    2016 Clinical Islet Xenotransplantation: A Step ForwardSouth African Journal of Science.  12:22-23. 2016
    2016 Pig Liver Xenotransplantation: A Review of Progress Toward the ClinicTransplantation.  100:2039-2047. 2016
    2016 Transplantation of the heart after circulatory deathAmerican Journal of Biochemistry and Biotechnology.  16:3063. 2016
    2016 Effect of Rho-kinase Inhibitor, Y27632, on Porcine Corneal Endothelial Cell Culture, Inflammation and Immune RegulationOcular Immunology and Inflammation.  24:579-593. 2016
    2016 Human antibody recognition of xenogeneic antigens (NeuGc and Gal) on porcine heart valves: could genetically modified pig heart valves reduce structural valve deterioration?Xenotransplantation.  23:370-380. 2016
    2016 Psychosocial challenges of xenotransplantation: the need for a multidisciplinary, religious, and cultural dialogueXenotransplantation.  23:335-337. 2016
    2016 Circulating organ-specific microRNAs serve as biomarkers in organ-specific diseases: Implications for organ allo- and xeno-transplantationInternational Journal of Molecular Sciences.  17. 2016
    2016 Thyroid hormone therapy and procurement of livers from brain-dead donorsNew York Journal of Mathematics.  41:270-273. 2016
    2016 Hormone resuscitation therapy for brain-dead donors – is insulin beneficial or detrimental?Surgery, gynecology & obstetrics.  30:754-759. 2016
    2016 Is successful orthotopic heart transplantation in the pig-to-non-human primate model required before proceeding to a clinical trial?Xenotransplantation.  23:328-329. 2016
    2016 Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft RecipientsAmerican Journal of Biochemistry and Biotechnology.  16:1999-2015. 2016
    2016 Thyroid hormone: relevance to xenotransplantationXenotransplantation.  23:293-299. 2016
    2016 Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacementTransplantation.  100:e25-e31. 2016
    2016 Modifying the sugar icing on the transplantation cakeGlycobiology.  26:571-581. 2016
    2016 Heart Xenotransplantation: Historical Background, Experimental Progress, and Clinical ProspectsSchizophrenia Bulletin.  101:1605-1613. 2016
    2016 Initial in vitro studies on tissues and cells from GTKO/CD46/NeuGcKO pigsXenotransplantation.  23:137-150. 2016
    2016 The pathobiology of pig-to-primate xenotransplantation: A historical reviewXenotransplantation.  23:83-105. 2016
    2016 Endoscopic biopsy of islet transplants in the gastric submucosal space provides evidence of islet graft rejection in diabetic pigsIslets.  8:1-12. 2016
    2016 Eomesoderminlo CTLA4hi Alloreactive CD8+ Memory T Cells Are Associated with Prolonged Renal Transplant Survival Induced by Regulatory Dendritic Cell Infusion in CTLA4 Immunoglobulin-Treated Nonhuman PrimatesTransplantation.  100:91-102. 2016
    2016 Expression of NeuGc on Pig Corneas and Its Potential Significance in Pig Corneal XenotransplantationCurrent Womens Health Reports.  35:105-113. 2016
    2016 First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 2b: Genetically modified source pigsXenotransplantation.  23:32-37. 2016
    2016 First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: Pre-clinical efficacy and complication data required to justify a clinical trialXenotransplantation.  23:46-52. 2016
    2016 First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Executive summaryXenotransplantation.  23:3-13. 2016
    2016 Persistence of Indirect but Not Direct T Cell Xenoresponses in Baboon Recipients of Pig Cell and Organ TransplantsAmerican Journal of Biochemistry and Biotechnology.  16:1917-1922. 2016
    2016 Report from IPITA-TTS opinion leaders meeting on the future of β-cell replacementTransplantation.  100:S1-S44. 2016
    2016 The role of genetically engineered pigs in xenotransplantation researchJournal of Pathology.  238:288-299. 2016
    2015 Recent advances in understanding xenotransplantation: Implications for the clinicExpert Review of Clinical Immunology.  11:1379-1390. 2015
    2015 A brief history of clinical xenotransplantationInternational Journal of Surgery.  23:205-210. 2015
    2015 Cell-based immunosuppression in kidney transplantation: The value of non-human primate studiesKidney International.  88:1196-1197. 2015
    2015 Immunobiological barriers to xenotransplantationInternational Journal of Surgery.  23:211-216. 2015
    2015 In vitro testing of an anti-CD40 monoclonal antibody, clone 2C10, in primates and pigsTransplant Immunology.  33:185-191. 2015
    2015 Potential alternative approaches to xenotransplantationInternational Journal of Surgery.  23:322-326. 2015
    2015 Progress toward clinical xenotransplantationInternational Journal of Surgery.  23:197-198. 2015
    2015 Systemic inflammation in xenograft recipients (SIXR): A new paradigm in pig-to-primate xenotransplantation?International Journal of Surgery.  23:301-305. 2015
    2015 The need for xenotransplantation as a source of organs and cells for clinical transplantationInternational Journal of Surgery.  23:199-204. 2015
    2015 Transgenic expression of human CD46: Does it reduce the primate T-cell response to pig endothelial cells?Xenotransplantation.  22:487-489. 2015
    2015 Xenograft bioprosthetic heart valves: Past, present and futureInternational Journal of Surgery.  23:280-284. 2015
    2015 Further evidence for sustained systemic inflammation in xenograft recipients (SIXR)Xenotransplantation.  22:399-405. 2015
    2015 David K. C. Cooper, MD, PhD: Professor of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, PATransplantation.  99:1310-1311. 2015
    2015 Experimental hepatocyte xenotransplantation - A comprehensive review of the literatureXenotransplantation.  22:239-248. 2015
    2015 Pig kidney graft survival in a baboon for 136 days: Longest life-supporting organ graft survival to dateXenotransplantation.  22:302-309. 2015
    2015 Liver transplantation for a giant mesenchymal hamartoma of the liver in an adult: Case report and review of the literatureWorld Journal of Gastroenterology.  21:6409-6416. 2015
    2015 MYROIDES INFECTION IN A BABOON AFTER PROLONGED PIG KIDNEY GRAFT SURVIVAL.Transplantation Direct.  1. 2015
    2015 Sequential monitoring and stability of Ex vivo-expanded autologous and nonautologous regulatory t cells following infusion in nonhuman primatesAmerican Journal of Biochemistry and Biotechnology.  15:1253-1266. 2015
    2015 The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigsInternational Journal of Molecular Sciences.  16:6545-6556. 2015
    2015 Initial in vivo experience of pig artery patch transplantation in baboons using mutant MHC (CIITA-DN) pigsTransplant Immunology.  32:99-108. 2015
    2015 Increased Procurement of Thoracic Donor Organs After Thyroid Hormone TherapySeminars in Thoracic and Cardiovascular Surgery.  27:123-132. 2015
    2015 Characterization of the cellular infiltrate in bioprosthetic heart valves explanted from patients with structural valve deteriorationXenotransplantation.  22:406-407. 2015
    2015 Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory proteinXenotransplantation.  22:310-316. 2015
    2015 Expression of NeuGc on pig heart valvesXenotransplantation.  22:153-154. 2015
    2015 Glucose metabolism in pigs expressing human genes under an insulin promoterXenotransplantation.  22:70-79. 2015
    2015 In vitro exposure of pig neonatal isletlike cell clusters to human bloodXenotransplantation.  22:317-324. 2015
    2015 Islet xenotransplantation: What is the optimal age of the islet-source pig?Xenotransplantation.  22:7-19. 2015
    2015 Pig-to-baboon heterotopic heart transplantation - Exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimensXenotransplantation.  22:211-220. 2015
    2015 Systemic inflammation in xenograft recipients precedes activation of coagulationXenotransplantation.  22:32-47. 2015
    2015 The case for xenotransplantationSurgery, gynecology & obstetrics.  29:288-293. 2015
    2014 The optimal hormonal replacement modality selection for multiple organ procurement from brain-dead organ donorsOutcomes Management.  7:17-27. 2014
    2014 Development of a consensus protocol to quantify primate anti-non-Gal xenoreactive antibodies using pig aortic endothelial cellsXenotransplantation.  21:555-566. 2014
    2014 Potential for clinical pancreatic islet xenotransplantationTransplant Research and Risk Management.  6:79-86. 2014
    2014 Progress in pig-to-non-human primate transplantation models (1998-2013): A comprehensive review of the literatureXenotransplantation.  21:397-419. 2014
    2014 The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of xenocorneal transplantationXenotransplantation.  21:420-430. 2014
    2014 Streptozotocin-associated lymphopenia in cynomolgus monkeysIslets.  6. 2014
    2014 Increased soluble CD154 (CD40 Ligand) levels in xenograft recipients correlate with the development of de novo anti-pig IgG antibodiesTransplantation.  97:502-508. 2014
    2014 Tribute to Carl-Gustav Groth (1933-2014), first president of the International Xenotransplantation AssociationXenotransplantation.  21:97-98. 2014
    2014 The Potential Role of Genetically-Modified Pig Mesenchymal Stromal Cells in XenotransplantationStem Cell Reviews and Reports.  10:79-85. 2014
    2014 A comparison of three methods of decellularization of pig corneas to reduce immunogenicity.International Journal of Ophthalmology.  7:587-593. 2014
    2014 A milestone in xenotransplantation researchXenotransplantation.  21:13-15. 2014
    2014 Are there advantages in the use of specific pathogen-free baboons in pig organ xenotransplantation models?Xenotransplantation.  21:287-290. 2014
    2014 Bioprosthetic heart valves of the futureXenotransplantation.  21:1-10. 2014
    2014 Characterization of porcine corneal endothelium for xenotransplantationSeminars in Ophthalmology.  29:127-135. 2014
    2014 Corneal blindness and xenotransplantationXenotransplantation.  21:99-114. 2014
    2014 Distribution of non-gal antigens in pig cornea: Relevance to corneal xenotransplantationCurrent Womens Health Reports.  33:390-397. 2014
    2014 Hematopoietic chimerism following allotransplantation of the spleen, splenocytes or kidney in pigsTransplant Immunology.  31:125-133. 2014
    2014 Kidney xenotransplantationKidney International.  85:265-275. 2014
    2014 Pig-to-monkey islet xenotransplantation using multi-transgenic pigsAmerican Journal of Biochemistry and Biotechnology.  14:2275-2287. 2014
    2014 Plasma free triiodothyronine (fT3) levels in baboons undergoing pig organ transplantation: Relevance to early recovery of organ functionXenotransplantation.  21:582-583. 2014
    2014 Regulation of human platelet aggregation by genetically modified pig endothelial cells and thrombin inhibitionXenotransplantation.  21:72-83. 2014
    2014 Role of P-selectin and P-selectin glycoprotein ligand-1 interaction in the induction of tissue factor expression on human platelets after incubation with porcine aortic endothelial cellsXenotransplantation.  21:16-24. 2014
    2014 The role of platelets in coagulation dysfunction in xenotransplantation, and therapeutic optionsXenotransplantation.  21:201-220. 2014
    2014 Thyroid hormone and the stunned myocardiumJournal of Endocrinology.  223:R1-R8. 2014
    2014 Thyroid hormone therapy in the management of 63,593 brain-dead organ donors: A retrospective analysisTransplantation.  98:1119-1127. 2014
    2014 Thyroid hormone therapy in the management of 63,593 brain-dead organ donors: A retrospective analysisTransplantation.  98:1019. 2014
    2013 Technique of endoscopic biopsy of islet allografts transplanted into the gastric submucosal space in pigsJournal of Prosthetic Dentistry.  22:2335-2344. 2013
    2013 New concepts of immune modulation in xenotransplantationTransplantation.  96:937-945. 2013
    2013 Islet xenotransplantation from genetically engineered pigsInternational Journal of Clinical and Laboratory Research.  18:695-702. 2013
    2013 Minimal effect of bortezomib in reducing anti-pig antibodies in human leukocyte antigen-sensitized patients: A pilot studyXenotransplantation.  20:429-437. 2013
    2013 Histopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejectionXenotransplantation.  20:292-307. 2013
    2013 Human T cells upregulate CD69 after coculture with xenogeneic genetically-modified pig mesenchymal stromal cellsJournal of Crohn's and Colitis.  285:23-30. 2013
    2013 Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune statusImmunology.  140:39-46. 2013
    2013 Is there a correlation between anti-pig antibody levels in humans and geographic location during childhood?Transplantation.  96:387-393. 2013
    2013 Ex vivo-expanded cynomolgus macaque regulatory T cells are resistant to Alemtuzumab-mediated cytotoxicityAmerican Journal of Biochemistry and Biotechnology.  13:2169-2178. 2013
    2013 Regulatory dendritic cell infusion prolongs kidney allograft survival in nonhuman primatesAmerican Journal of Biochemistry and Biotechnology.  13:1989-2005. 2013
    2013 Comparison of proliferative capacity of genetically-engineered pig and human corneal endothelial cellsOphthalmic Research.  49:127-138. 2013
    2013 Toward clinical islet xenotransplantation - Are revisions to the IXA guidelines warranted?Xenotransplantation.  20:68-74. 2013
    2013 Commentary: Limitations of the pig-to-non-human primate islet transplantation modelXenotransplantation.  20:2-4. 2013
    2013 Post-transplant repopulation of naïve and memory T cells in blood and lymphoid tissue after alemtuzumab-mediated depletion in heart-transplanted cynomolgus monkeysTransplant Immunology.  29:88-98. 2013
    2013 The potential of genetically-engineered pigs in providing an alternative source of organs and cells for transplantationJournal of Biomedical Research.  27:249-253. 2013
    2012 A syndrome of severe hypoglycemia and acidosis in young immunosuppressed diabetic monkeys and pigs-association with sepsisTransplantation.  94:1187-1191. 2012
    2012 John Collins Warren (1778-1856): An American surgeon in LondonJournal of Refractive Surgery.  345. 2012
    2012 Clinical islet xenotransplantation: How close are we?Gynecologic Investigation.  61:3046-3055. 2012
    2012 Early islet damage after direct exposure of pig islets to blood: Has humoral immunity been underestimated?Journal of Prosthetic Dentistry.  21:1791-1802. 2012
    2012 Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional spermInternational Journal of Pharmaceutical and Healthcare Marketing.  11:715-726. 2012
    2012 Comparison of hematologic, biochemical, and coagulation parameters in α1,3-galactosyltransferase gene-knockout pigs, wild-type pigs, and four primate speciesXenotransplantation.  19:342-354. 2012
    2012 Anti-gal antibodies in α1,3-galactosyltransferase gene-knockout pigsXenotransplantation.  19:305-310. 2012
    2012 Do mesenchymal stem cells function across species barriers? Relevance for xenotransplantationXenotransplantation.  19:273-285. 2012
    2012 Human T-cell proliferation in response to thrombin-activated GTKO pig endothelial cellsXenotransplantation.  19:311-316. 2012
    2012 Immunobiology of liver xenotransplantationExpert Review of Clinical Immunology.  8:621-634. 2012
    2012 Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantationTransplant International.  25:882-896. 2012
    2012 Potential benefits and risks of clinical xenotransplantationTransplant Research and Risk Management.  4:7-17. 2012
    2012 Collagenous colitis-like condition in immunosuppressed infant baboonsInflammatory Bowel Diseases.  18:1325-1332. 2012
    2012 Costimulation blockade in pig artery patch xenotransplantation - A simple model to monitor the adaptive immune response in nonhuman primatesXenotransplantation.  19:221-232. 2012
    2012 Platelet aggregation in humans and nonhuman primates: Relevance to xenotransplantationXenotransplantation.  19:233-243. 2012
    2012 The value of xenotransplantation.Immunohorizons.  97:54. 2012
    2012 Clinical lung xenotransplantation - What donor genetic modifications may be necessary?Xenotransplantation.  19:144-158. 2012
    2012 Partial improvement of dupuytren contracture following a wasp stingJournal of Hand Surgery (American Volume).  37:1105-1106. 2012
    2012 T-cell-based immunosuppressive therapy inhibits the development of natural antibodies in infant baboonsTransplantation.  93:769-776. 2012
    2012 Induced regulatory T cells: Mechanisms of conversion and suppressive potentialHuman Immunology.  73:328-334. 2012
    2012 Clinical xenotransplantation: The next medical revolution?Lancet.  379:672-683. 2012
    2012 T-lymphocyte homeostasis and function in infant baboons: Implications for transplantationTransplant International.  25:218-228. 2012
    2012 The future of bioprosthetic heart valvesIndian Journal of Medical Research.  135:150-151. 2012
    2012 Genetically-engineered pig-to-baboon liver xenotransplantation: Histopathology of xenografts and native organsPLoS ONE.  7. 2012
    2012 A brief history of cross-species organ transplantation.Geriatric Nursing.  25:49-57. 2012
    2012 Adipose-derived mesenchymal stromal cells from genetically modified pigs: Immunogenicity and immune modulatory propertiesJournal of Adolescent Research.  14:494-504. 2012
    2012 Porcine alanine transaminase after liver allo-and xenotransplantationXenotransplantation.  19:52-55. 2012
    2012 Porcine bioprosthetic heart valves: The next generationCureus.  164:177-185. 2012
    2012 The effect of Gal expression on pig cells on the human T-cell xenoresponseXenotransplantation.  19:56-63. 2012
    2011 Edward gerjuoy: From physics to law and back againPhysics in Perspective.  13:433-455. 2011
    2011 Relative efficiency of porcine and human cytotoxic T-lymphocyte antigen 4 immunoglobulin in inhibiting human CD4 + T-cell responses co-stimulated by porcine and human B7 moleculesImmunology.  134:386-397. 2011
    2011 Thrombocytopenia after pig-to-baboon liver xenotransplantation: Where do platelets go?Xenotransplantation.  18:320-327. 2011
    2011 A record of international meetings on xenotransplantation 1988-2010Xenotransplantation.  18:229-231. 2011
    2011 Cardiac xenotransplantation technology provides materials for improved bioprosthetic heart valvesJournal of Thoracic and Cardiovascular Surgery.  142:238-239. 2011
    2011 Initial in vitro investigation of the human immune response to corneal cells from genetically engineered pigsInvestigative Ophthalmology & Visual Science.  52:5278-5286. 2011
    2011 Clinical pig liver xenotransplantation: How far do we have to go?Xenotransplantation.  18:158-167. 2011
    2011 Genetically-modified pig mesenchymal stromal cells: Xenoantigenicity and effect on human T-cell xenoresponsesXenotransplantation.  18:183-195. 2011
    2011 Therapeutic issues in the treatment of vascularized xenotransplants using gal-knockout donors in nonhuman primatesInternational Journal of Clinical and Laboratory Research.  16:222-230. 2011
    2011 Xenotransplantation-the future of corneal transplantation?Current Womens Health Reports.  30:371-378. 2011
    2011 Attempted depletion of passenger leukocytes by irradiation in pigs.Journal of Transplantation.  2011:928759. 2011
    2011 Giant gallstone: A case reportInternational Journal of Surgery Case Reports.  2:228-229. 2011
    2011 The immense potential of xenotransplantation in surgeryInternational Journal of Surgery.  9:122-129. 2011
    2010 The spleen as a site for hematopoiesisTransplantation.  90:1040-1041. 2010
    2010 Multivisceral xenotransplantation-does it have a future?Xenotransplantation.  17:418-422. 2010
    2010 Non-human primate regulatory T cells: Current biology and implications for transplantationTransplantation.  90:811-816. 2010
    2010 Hepatic function after genetically engineered pig liver transplantation in baboonsTransplantation.  90:483-493. 2010
    2010 An in vitro model of pig liver xenotransplantation-pig complement is associated with reduced lysis of wild-type and genetically modified pig cellsXenotransplantation.  17:370-378. 2010
    2010 Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by anti-nonGal IgG binding to porcine aortic endothelial cellsJournal of Thrombosis and Haemostasis.  8:2001-2010. 2010
    2010 The immunology of corneal xenotransplantation: A review of the literatureXenotransplantation.  17:338-349. 2010
    2010 Recipient tissue factor expression is associated with consumptive coagulopathy in pig-to-primate kidney xenotransplantationAmerican Journal of Biochemistry and Biotechnology.  10:1556-1568. 2010
    2010 Genetically Engineered Pigs as a Source for Clinical Red Blood Cell TransfusionBio-Medical Materials and Engineering.  30:365-380. 2010
    2010 Outwitting evolution: Honorary Fellowship LectureXenotransplantation.  17:171-180. 2010
    2010 Investigation of lymphocyte depletion and repopulation using alemtuzumab (Campath-1H) in cynomolgus monkeysAmerican Journal of Biochemistry and Biotechnology.  10:773-783. 2010
    2010 Insulin secretion and glucose metabolism in alpha 1,3-galactosyltransferase knock-out pigs compared to wild-type pigsXenotransplantation.  17:131-139. 2010
    2010 Overcoming the barriers to xenotransplantation: Prospects for the futureExpert Review of Clinical Immunology.  6:219-230. 2010
    2010 Impact of thrombocytopenia on survival of baboons with genetically modified pig liver transplantsAmerican Journal of Biochemistry and Biotechnology.  10:273-285. 2010
    2010 Investigation of potential carbohydrate antigen targets for human and baboon antibodiesXenotransplantation.  17:197-206. 2010
    2010 Pig heart xenotransplantation as a bridge to allotransplantationThe Journal of heart transplantation.  29:838-840. 2010
    2010 The potential of genetically-modified pig mesenchymal stromal cells in xenotransplantationXenotransplantation.  17:3-5. 2010
    2009 Cyclophosphamide dosage in pigsAging Clinical and Experimental Research.  14:91-92. 2009
    2009 Effect of the αgal epitope on the response to small intestinal submucosa extracellular matrix in a nonhuman primate modelTissue Engineering: Parts A, B, and C.  15:3877-3888. 2009
    2009 Long-term controlled normoglycemia in diabetic non-human primates after transplantation with hCD46 transgenic porcine isletsAmerican Journal of Biochemistry and Biotechnology.  9:2716-2726. 2009
    2009 Genetically engineered pig red blood cells for clinical transfusion: Initial in vitro studiesTransfusion.  49:2418-2429. 2009
    2009 Commentary: How important is the anti-gal antibody response following the implantation of a porcine bioprosthesis?Journal of Heart Valve Disease.  18:671-672. 2009
    2009 Endoscopic gastric submucosal transplantation of islets (ENDO-STI): Technique and initial results in diabetic pigsAmerican Journal of Biochemistry and Biotechnology.  9:2485-2496. 2009
    2009 How important is the anti-Gal antibody response following the implantation of a porcine bioprosthesis?Journal of Heart Valve Disease.  18:671-672. 2009
    2009 Monitoring of porcine and baboon cytomegalovirus infection in xenotransplantationXenotransplantation.  16:535-536. 2009
    2009 Pig liver xenotransplantation as a bridge to allotransplantation: Which patients might benefit?Transplantation.  88:1041-1049. 2009
    2009 Production and characterization of transgenic pigs expressing porcine CTLA4-IgXenotransplantation.  16:477-485. 2009
    2009 Current status of xenotransplantation and prospects for clinical applicationXenotransplantation.  16:263-280. 2009
    2009 The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-Chapter 4: Pre-clinical efficacy and complication data required to justify a clinical trialXenotransplantation.  16:229-238. 2009
    2009 The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-Executive summaryXenotransplantation.  16:196-202. 2009
    2009 Coagulation dysregulation as a barrier to xenotransplantation in the primateTransplant Immunology.  21:75-80. 2009
    2009 Xenotransplantation of solid organs in the pig-to-primate modelTransplant Immunology.  21:87-92. 2009
    2009 Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantationAmerican Journal of Biochemistry and Biotechnology.  9:1006-1016. 2009
    2009 The innate immune response and activation of coagulation in ±1,3-galactosyltransferase gene-knockout xenograft recipientsTransplantation.  87:805-812. 2009
    2009 Invited commentaryXenotransplantation.  16:58-60. 2009
    2009 A review of studies relating to thyroid hormone therapy in brain-dead organ donorsFrontiers in Bioscience.  14:3750-3770. 2009
    2009 Identification of αgal as the major target for human anti-pig antibodiesXenotransplantation.  16:47-49. 2009
    2008 Absence of replication of porcine endogenous retrovirus and porcine lymphotropic herpesvirus type 1 with prolonged pig cell microchimerism after pig-to-baboon xenotransplantationJournal of Virology.  82:12441-12448. 2008
    2008 In vitro investigation of pig cells for resistance to human antibody-mediated rejectionTransplant International.  21:1163-1174. 2008
    2008 Rejection of cardiac xenografts transplanted from α1,3- galactosyltransferase gene-knockout (GalT-KO) pigs to baboonsAmerican Journal of Biochemistry and Biotechnology.  8:2516-2526. 2008
    2008 The choice of anatomical site for islet transplantationJournal of Prosthetic Dentistry.  17:1005-1014. 2008
    2008 Hormonal therapy to the brain-dead potential organ donor: The misnomer of the "papworth cocktail"Transplantation.  86:1479. 2008
    2008 Suppressive efficacy and proliferative capacity of human regulatory t cells in allogeneic and xenogeneic responsesTransplantation.  86:1452-1462. 2008
    2008 Update: Cardiac xenotransplantationInternational Journal of Clinical and Laboratory Research.  13:531-535. 2008
    2008 Atorvastatin down-regulates the primate cellular response to porcine aortic endothelial cells in vitroTransplantation.  86:733-737. 2008
    2008 Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cellsTransplantation.  86:702-709. 2008
    2008 The Choice of Anatomical Site for Islet Transplantation.Journal of Prosthetic Dentistry.  17:1005-1014. 2008
    2008 Of HIV, grief and TOPSouth African Medical Journal.  98:498. 2008
    2008 Erratum: Safe induction of diabetes by high-dose streptozotocin in pigs (Pancreas (2008) 36, 3, (328))Pancreas.  36:328. 2008
    2008 Liver xenografts for the treatment of acute liver failure: Clinical and experimental experience and remaining immunologic barriersLiver Transplantation and Surgery.  14:425-434. 2008
    2008 High-Throughput Screening of Glycan-Binding Proteins Using Miniature Pig Kidney N-Glycan-Immobilized BeadsArtificial Organs.  15:215-223. 2008
    2008 Islet xenotransplantation: The pig-to-non-human primate modelXenotransplantation.  15:104-106. 2008
    2008 Hormonal resuscitation therapy in the management of the brain-dead potential organ donorInternational Journal of Surgery.  6:3-4. 2008
    2008 Frankenswine, or bringing home the bacon: How close are we to clinical trials in xenotransplantation?Organogenesis.  4:1-10. 2008
    2008 Metabolic aspects of pig-to-monkey (Macaca fascicularis) islet transplantation: Implications for translation into clinical practiceReferences en Gynecologie Obstetrique.  51:120-129. 2008
    2008 Recent advances in pig-to-human organ and cell transplantationExpert Opinion on Biological Therapy.  8:1-4. 2008
    2008 Safe induction of diabetes by high-dose streptozotocin in pigsPancreas.  36:31-38. 2008
    2008 Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from α1,3-galactosyltransferase gene-knockout pigs in baboonsOmega.  172:1471-1481. 2008
    2007 Late onset of development of natural anti-nonGal antibodies in infant humans and baboons: Implications for xenotransplantation in infantsTransplant International.  20:1050-1058. 2007
    2007 Response to commentaries on "α1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: Where do we go from here?"Transplantation.  84:1212-1213. 2007
    2007 Knowledge and use of emergency contraception among women in the Western Cape province of South Africa: A cross-sectional studyAnnals of Clinical Microbiology and Antimicrobials.  7. 2007
    2007 Erratum: Babesia as a complication of immunosuppression following pig-to-baboon heart transplantation (Xenotransplantation (2007) 14,2, (162-165) DOI: 10.1111/j.1399-3089.2007.00375.x)Xenotransplantation.  14:374. 2007
    2007 Erratum: The potential of statins in xenotransplantation (Xenotransplantation (2007) 14,2, (100-103) DOI: 10.1111/j.1399-3089.2007.00389. x)Xenotransplantation.  14:374. 2007
    2007 Rapid loss of intraportally transplanted islets: An overview of pathophysiology and preventive strategiesXenotransplantation.  14:288-297. 2007
    2007 α1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: Where do we go from here?Transplantation.  84:1-7. 2007
    2007 Acute gastric dilatation after porcine islet transplantation in a cynomolgus monkey - Case history and review of the literatureXenotransplantation.  14:265-270. 2007
    2007 The pig-to-primate immune response: Relevance for xenotransplantationXenotransplantation.  14:227-235. 2007
    2007 Using α1,3-galactosyltransferase gene-knockout pig organs in nonhuman primatesInternational Journal of Clinical and Laboratory Research.  12:158-163. 2007
    2007 Pig-to-Non-human Primate Heart Transplantation: Immunologic Progress Over 20 YearsThe Journal of heart transplantation.  26:210-218. 2007
    2007 The potential of statins in xenotransplantation: CommentaryXenotransplantation.  14:100-103. 2007
    2007 Progress in xenotransplantation following the introduction of gene-knockout technologyTransplant International.  20:107-117. 2007
    2007 Babesia as a complication of immunosuppression following pig-to-baboon heart transplantationXenotransplantation.  14:162-165. 2007
    2007 Gene expression of porcine lymphotrophic herpesvirus-1 in miniature swine with posttransplant lymphoproliferative disorderTransplantation.  83:87-90. 2007
    2007 Isolation outcome and functional characteristics of young and adult pig pancreatic islets for transplantation studiesXenotransplantation.  14:74-82. 2007
    2007 Reduction of early graft loss after intraportal porcine islet transplantation in monkeysTransplantation.  83:202-210. 2007
    2007 Rene Kuss's clinical experience with pig kidney transplantation in 1966 [4]Xenotransplantation.  14:93. 2007
    2006 Hormonal therapy of the brain-dead organ donor: Experimental and clinical studiesTransplantation.  82:1396-1401. 2006
    2006 Extended coagulation profiles of healthy baboons and of baboons rejecting GT-KO pig heart graftsXenotransplantation.  13:522-528. 2006
    2006 Measurement of anti-CD154 monoclonal antibody in primate sera by competitive inhibition ELISAXenotransplantation.  13:566-570. 2006
    2006 Primitive hematopoietic cell populations reside in the spleen: Studies in the pig, baboon, and humanExperimental Hematology.  34:1573-1582. 2006
    2006 Selected physiologic compatibilities and incompatibilities between human and porcine organ systemsXenotransplantation.  13:488-499. 2006
    2006 Community attitudes towards sexual activity and childbearing by HIV-positive people in South AfricaACRPMonitor.  18:772-776. 2006
    2006 Induction of diabetes in cynomolgus monkeys with high-dose streptozotocin: Adverse effects and early responsesPancreas.  33:287-292. 2006
    2006 The status of legal termination of pregnancy in South AfricaSouth African Medical Journal.  96:1056. 2006
    2006 Xenotransplantation - Will tolerance be essential? [6]Nephrology Dialysis Transplantation.  21:2991-2992. 2006
    2006 ABO-incompatible allotransplantation as a basis for clinical xenotransplantationXenotransplantation.  13:390-399. 2006
    2006 Antibodies directed to pig non-Gal antigens in naïve and sensitized baboonsXenotransplantation.  13:400-407. 2006
    2006 Allosensitization does not increase the risk of xenoreactivity to α1,3-galactosyltransferase gene-knockout miniature swine in patients on transplantation waiting listsTransplantation.  82:314-319. 2006
    2006 Engraftment potential of adult spleen cells in vitro and in vivoTransplant Immunology.  16:131. 2006
    2006 Allosensitized humans are at no greater risk of humoral rejection of GT-KO pig organs than other humansXenotransplantation.  13:357-365. 2006
    2006 Islet xenotransplantation: Are we really ready for clinical trials?American Journal of Biochemistry and Biotechnology.  6:1269-1274. 2006
    2006 Pig-to-nonhuman primate islet xenotransplantation: A review of current problemsJournal of Prosthetic Dentistry.  15:89-104. 2006
    2006 Immunologic benefits of spleen transplantation in the absence of graft-versus-host disease [7]Acta Neuropsychiatrica.  243:710-711. 2006
    2006 PERV methodologyXenotransplantation.  13:171. 2006
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    2006 Xenotransplantation: The road aheadInternational Journal of Clinical and Laboratory Research.  11:151-153. 2006
    2006 The IJS welcomes two great pioneersInternational Journal of Surgery.  4:7-8. 2006
    2006 Facilitating physiologic self-regeneration: A step beyond islet cell replacementPharmaceutical Research.  23:227-242. 2006
    2006 Incidence and cytotoxicity of antibodies in cynomolgus monkeys directed to nonGal antigens, and their relevance for experimental modelsTransplant International.  19:158-165. 2006
    2006 Buccal mucosal cell immunohistochemistry: A simple method of determining the ABH phenotype of baboons, monkeys, and pigsXenotransplantation.  13:63-68. 2006
    2006 Cardiac transplantation following storage of the donor heart by a portable hypothermic perfusion system: the initial clinical experience.Annals of Psychiatry and Mental Health.  552-554. 2006
    2006 Journal requirements for manuscripts on clinical trials of xenotransplantationXenotransplantation.  13:2. 2006
    2006 Letter from the EditorsXenotransplantation.  13:1. 2006
    2005 Lack of cardiac differentiation in c-kit-enriched porcine bone marrow and spleen hematopoietic cell cultures using 5-azacytidineBrain Stimulation.  180:195-203. 2005
    2005 Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneysNature Medicine.  11:1295-1298. 2005
    2005 Immunological unresponsiveness in chimeric miniature swine following MHC-mismatched spleen transplantationTransplantation.  80:1791-1804. 2005
    2005 alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months.Transplantation.  80:1493-1500. 2005
    2005 Localized myocardial infarction following pig-to-baboon heart transplantationXenotransplantation.  12:489-491. 2005
    2005 α1,3-galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 monthsTransplantation.  80:1493-1500. 2005
    2005 Preformed antibodies to α1,3-galactosyltransferase gene-knockout (GT-KO) pig cells in humans, baboons, and monkeys: Implications for xenotransplantationTransplantation Proceedings.  37:3514-3515. 2005
    2005 Pig-to-nonhuman primate organ xenotransplantationInternational Journal of Clinical and Laboratory Research.  10:234-239. 2005
    2005 Carbohydrates in xenotransplantationImmunology and Cell Biology.  83:396-404. 2005
    2005 Heart transplantation: The contributions of Christiaan Barnard and the University of Cape Town/Groote Schuur HospitalWorld Journal of Surgery.  29:953-961. 2005
    2005 Reducing Gal expression on the pig organ - A retrospective reviewXenotransplantation.  12:278-285. 2005
    2005 Porcine red blood cells express a polyagglutinable red blood cell phenotype [1] (multiple letters)Transfusion.  45:1035-1037. 2005
    2005 Which patients first? Planning the first clinical trial of xenotransplantation: A case for cardiac bridgingXenotransplantation.  12:168-172. 2005
    2005 The ethics debate in relation to xenotransplantationRevue Scientifique et Technique- Office International des Epizooties.  24:335-342. 2005
    2005 How strong is the T cell response in the pig-to-primate model?Xenotransplantation.  12:85-87. 2005
    2005 HIV-infected women in ART programmes [5]Lancet.  365:655-656. 2005
    2005 Histopathology of spleen allograft rejection in miniature swineInternational Journal of Experimental Pathology.  86:57-66. 2005
    2005 Porcine hematopoietic progenitor cell transplantation in nonhuman primates: A review of progressTransplantation.  79:1-9. 2005
    2005 Draft reports for public comment from the US Secretary's Advisory Committee on Xenotransplantation.Xenotransplantation.  12:255-257. 2005
    2005 Early weaning of piglets fails to exclude porcine lymphotropic herpesvirusXenotransplantation.  12:59-62. 2005
    2005 Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: Initial experienceNature Medicine.  11:29-31. 2005
    2005 Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissueNature Medicine.  11:32-34. 2005
    2005 Potential of aspirin to inhibit thrombotic microangiopathy in α1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboonsTransplantation Proceedings.  37:489-490. 2005
    2005 Troponin T levels in baboons with pig heterotopic heart transplantsThe Journal of heart transplantation.  24:92-94. 2005
    2004 T cells from presensitized donors fail to cause graft-versus-host disease in a pig-to-mouse xenotransplantation modelTransplantation.  78:1609-1617. 2004
    2004 Reduction of consumptive coagulopathy using porcine cytomegalovirus-free cardiac porcine grafts in pig-to-primate xenotransplantationTransplantation.  78:1449-1453. 2004
    2004 Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboonsXenotransplantation.  11:416-425. 2004
    2004 Failed contraception? [2]South African Medical Journal.  94:600. 2004
    2004 Bone marrow transplantation from α1,3-galactosyltransferase gene-knockout pigs in baboonsXenotransplantation.  11:361-370. 2004
    2004 Initial experience with the human anti-human CD154 monoclonal antibody, ABI793, in pig-to-baboon xenotransplantationXenotransplantation.  11:353-360. 2004
    2004 Investigation of red blood cells from α1,3-galactosyltransferase- knockout pigs for human blood transfusionTransfusion.  44:1004-1012. 2004
    2004 Letter to the editor [3]Xenotransplantation.  11:380-381. 2004
    2004 Letter to the editor [4]Xenotransplantation.  11:382. 2004
    2004 α1-3-galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-gal antobodiesTransplantation.  78:15-20. 2004
    2004 Acute vascular rejection of xenografts: Roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activityTransplantation.  77:1735-1741. 2004
    2004 Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantationJournal of Infectious Diseases.  189:1628-1633. 2004
    2004 Non-specific removal of antibodies in patients with idiopathic dilated cardiomyopathy: Implications for xenotransplantationThe Journal of heart transplantation.  23:623-626. 2004
    2004 Pig spleen transplantation induces transient hematopoietic cell chimerism in baboons [2]Xenotransplantation.  11:298-300. 2004
    2004 Transfusion of pig red blood cells into baboons [1]Xenotransplantation.  11:295-297. 2004
    2004 The Surgical Anatomy of Experimental and Clinical Thoracic Organ TransplantationTexas Heart Institute Journal.  31:61-68. 2004
    2004 Reduction of anti-Galα1,3Gal antibodies by infusion of types 2 and 6 gal trisaccharides conjugated to poly-L-lysineXenotransplantation.  11:210-215. 2004
    2004 Suppression of Natural and Elicited Antibodies in Pig-to-Baboon Heart Transplantation Using a Human Anti-Human CD154 mAb-Based RegimenAmerican Journal of Biochemistry and Biotechnology.  4:363-372. 2004
    2004 Xenotransplantation Manuscripts Now Published OnlineEarlyXenotransplantation.  11:109. 2004
    2004 Alloantibody and xenoantibody cross-reactivity in transplantationTransplantation.  77:1-5. 2004
    2004 Absence of humoral and cellular alloreactivity in baboons sensitized to pig antigensXenotransplantation.  11:27-32. 2004
    2004 Galα1,3Gal expression on porcine pancreatic islets, testis, spleen, and thymusXenotransplantation.  11:101-106. 2004
    2004 In vitro and in vivo investigation of a novel monoclonal antibody to plasma cells (W5 mAb)Xenotransplantation.  11:78-90. 2004
    2004 Initial investigation of the potential of modified porcine erythrocytes for transfusion in primatesXenotransplantation.  11:18-26. 2004
    2004 Posttransplant lymphoproliferative disease after allogeneic transplantation of the spleen in miniature swine.Transplantation.  78:286-291. 2004
    2004 Relative effects of GAL+ and GALlow/- porcine hematopoietic cells on primate platelet aggregation and endothelial cell activation: Implications for the induction of mixed hematopoietic chimerism in the pig-to-primate modelXenotransplantation.  11:72-77. 2004
    2004 Statement on allogeneic and xenogeneic transplantation by Fifty-Seventh World Health Assembly, 22 May 2004.Xenotransplantation.  11:390. 2004
    2004 Xenotransplantation: Letter from the EditorsXenotransplantation.  11:1. 2004
    2003 Correlation of Biochemical and Hematological Changes with Graft Failure Following Pig Heart and Kidney Transplantation in BaboonsAmerican Journal of Biochemistry and Biotechnology.  3:1510-1519. 2003
    2003 Pig kidney transplantation in baboons treated intravenously with a bovine serum albumin-Galα1-3Gal conjugateXenotransplantation.  10:606-614. 2003
    2003 An investigation of the effect of thalidomide on anti-gal antibody production in baboonsXenotransplantation.  10:470-474. 2003
    2003 Porcine red blood cells as a source of blood transfusion in humansXenotransplantation.  10:384-386. 2003
    2003 Reduced efficacy of ganciclovir against porcine and baboon cytomegalovirus in pig-to-baboon xenotransplantationAmerican Journal of Biochemistry and Biotechnology.  3:1057-1064. 2003
    2003 Clinical xenotransplantion - How close are we?Lancet.  362:557-559. 2003
    2003 Can spleen transplantation induce tolerance? A review of the literatureTransplant International.  16:451-460. 2003
    2003 Depletion of anti-Gal antibodies by the intravenous infusion of Gal type 2 and 6 glycoconjugates in baboonsXenotransplantation.  10:357-367. 2003
    2003 Inhibition of baboon platelet aggregation in vitro and in vivo by the garlic derivative, ajoeneXenotransplantation.  10:374-379. 2003
    2003 Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantationTransplantation.  75:1841-1847. 2003
    2003 Spleen transplantation in miniature swine: Surgical technique and results in major histocompatibility complex-matched donor and recipient pairsTransplantation.  75:1799-1806. 2003
    2003 Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsivenessTransplantation.  75:1615-1624. 2003
    2003 ABO-incompatible organ and bone marrow transplantation: Current statusTransplant International.  16:291-299. 2003
    2003 Xenogeneic thymus transplantation in a pig-to-baboon modelTransplantation.  75:282-291. 2003
    2003 6th Congress of the International Xenotransplantation AssociationXenotransplantation.  10:7-9. 2003
    2003 An exploratory investigation of the effect of arsenic trioxide on anti-Gal antibody production in baboonsXenotransplantation.  10:80-87. 2003
    2003 An investigation of the specificity of induced anti-pig antibodies in baboonsXenotransplantation.  10:88-93. 2003
    2003 Clinical xenotransplantation: The next great surgical revolution?Formosan Journal of Surgery.  36:51-54. 2003
    2003 Models of xenotransplantation toleranceInternational Journal of Clinical and Laboratory Research.  8:83-88. 2003
    2003 Neurotoxicity of leflunomide in baboons [2]Xenotransplantation.  10:187-188. 2003
    2003 Outwitting evolution - Progress towards clinical xenotransplantationJournal of Surgery -Surgical Associates-.  1:9-14. 2003
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    2002 Therapeutic interventions in xenotransplantationAlabama Medicine. Quarterly publication of the Medical Association of the state of Alabama.  2:105-119. 2002
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    2002 Promotion of xenogeneic hematopoietic chimerism in rodents by mononuclear phagocyte depletionXenotransplantation.  9:402-409. 2002
    2002 Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cellsTransplantation.  74:1159-1166. 2002
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    2002 Xenotransplant cardiac chimera: Immune tolerance of adult stem cells: Invited commentarySchizophrenia Bulletin.  74:24. 2002
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    2002 Activation of human endothelial cells by mobilized porcine leukocytes in vitro: Implications for mixed chimerism in xenotransplantationTransplantation.  73:1302-1309. 2002
    2002 Will the pig solve the transplantation backlog?Journal of Cardiovascular Electrophysiology.  53:133-147. 2002
    2002 Anti-Galα1-3Gal IgM and IgG antibody levels in sera of humans and old world non-human primatesXenotransplantation.  9:148-154. 2002
    2002 Modulation of the in vivo primate anti-Gal response through administration of anti-idiotypic antibodiesXenotransplantation.  9:106-114. 2002
    2002 Depletion of anti-gal antibodies in baboons by intravenous therapy with bovine serum albumin conjugated to Gal oligosaccharidesTransplantation.  73:129-139. 2002
    2002 Pig hematopoietic cell chimerism in baboons conditioned with a nonmyeloablative regimen and CD154 blockadeTransplantation.  73:12-22. 2002
    2002 Xenotransplantation so close, but yet so farTransplantation.  73:1-2. 2002
    2002 Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockadeXenotransplantation.  9:3-13. 2002
    2002 Anti-CD154 monoclonal antibody and thromboembolism revisited [2]Transplantation.  74:416-417. 2002
    2002 Xenotransplantation and tolerance.Frontiers in Bioscience.  7. 2002
    2001 Transplantation of islets of Langerhans: New developmentsSwiss Medical Weekly.  131:671-680. 2001
    2001 CD40-CD154 pathway blockade requires host macrophages to induce humoral unresponsiveness to pig hematopoietic cells in baboonsTransplantation.  72:1759-1768. 2001
    2001 Pig kidney transplantation in baboons: Anti-galα1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulationTransplantation.  72:1743-1752. 2001
    2001 Assessment of methotrexate as a potential immunosuppressive agent in baboonsThe Journal of heart transplantation.  20:1335-1339. 2001
    2001 Xenotransplantation: Letter from the editorXenotransplantation.  8:223. 2001
    2001 Clearance of mobilized porcine peripheral blood progenitor cells is delayed by depletion of the phagocytic reticuloendothelial system in baboonsTransplantation.  72:1278-1285. 2001
    2001 Modulation of platelet aggregation in baboons: Implications for mixed chimerism in xenotransplantation. I. The roles of individual components of a transplantation conditioning regimen and of pig peripheral blood progenitor cellsTransplantation.  72:1299-1305. 2001
    2001 Modulation of platelet aggregation in baboons: Implications for mixed chimerism in xenotransplantation. II. The effects of cyclophosphamide on pig peripheral blood progenitor cell-induced aggregationTransplantation.  72:1306-1310. 2001
    2001 Effects of specific anti-B and/or anti-plasma cell immunotherapy on antibody production in baboons: Depletion of CD20- and CD22-positive B cells does not result in significantly decreased production of anti-αGal antibodyXenotransplantation.  8:157-171. 2001
    2001 Porcine hematopoietic cell xenotransplantation in nonhuman primates is complicated by thrombotic microangiopathymSystems.  27:1227-1236. 2001
    2001 Mechanisms of thrombotic microangiopathy following xenogeneic hematopoietic progenitor cell transplantationTransplantation.  71:1601-1609. 2001
    2001 Xenotransplantation: Letter from the editorXenotransplantation.  8:81. 2001
    2001 Effects of xenogeneic thymic transplantation in baboonsTransplantation Proceedings.  33:766. 2001
    2001 The potential role of xenotransplantation in treating endstage cardiac disease: A summary of the report of the Xenotransplantation Advisory Committee of the International Society for Heart and Lung TransplantationInternational Journal of Disaster Resilience in the Built Environment.  16:105-109. 2001
    2001 Report: International Xenotransplantation AssociationXenotransplantation.  8:2. 2001
    2001 Xenotransplantation: EditorialXenotransplantation.  8:1. 2001
    2001 Anti-CD154 monoclonal antibody and thromboembolismTransplantation.  71:491. 2001
    2001 Cardiac hyperacute rejection: A new look or a skewed look at an old problem? [1]The Journal of heart transplantation.  20:103-105. 2001
    2001 Total depletion and suppression of natural and induced anti-pig antibodies in baboons.The Journal of heart transplantation.  20:214. 2001
    2001 Christiaan Barnard and his contributions to heart transplantationThe Journal of heart transplantation.  20:599-610. 2001
    2001 Christiaan Neethling Barnard.Pathology International.  24:527-528. 2001
    2001 Immunosuppression for pig-to-nonhuman primate organ graftingInternational Journal of Clinical and Laboratory Research.  6:19-25. 2001
    2001 Letter to EditorXenotransplantation.  8:80. 2001
    2001 Miniature swine and hDAF pig kidney transplantation in baboons treated with a nonmyeloablative regimen and CD154 blockadeTransplantation Proceedings.  33:716. 2001
    2001 The pig as a source of cardiac xenograftsJournal of Cardiac Surgery.  16:345-356. 2001
    2001 XenotransplantationJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  79:129-223. 2001
    2000 Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primatesTransplantation.  70:1323-1331. 2000
    2000 Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates. Transplantation 2000; 70:1323Transplantation.  70:1273-1274. 2000
    2000 Inhibition of platelet aggregation in baboons: Therapeutic implications for xenotransplantationXenotransplantation.  7:247-257. 2000
    2000 Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: Experience with 320 aphereses in baboonsXenotransplantation.  7:181-185. 2000
    2000 Are pigs transgenic for human complement regulatory proteins necessary for xenotransplantationTransplantation.  70:567-568. 2000
    2000 A nonmyeloablative regimen with CD40L blockade leads to humoral and cellular hyporesponsiveness to pig hematopoietic cells in baboonsTransplantation Proceedings.  32:1100. 2000
    2000 Coagulation/thrombotic disorders associated with organ and cell xenotransplantationTransplantation Proceedings.  32:1099. 2000
    2000 Effect of B cell/plasma cell depletion or suppression on Anti-Gal antibody in the baboonTransplantation Proceedings.  32:1009. 2000
    2000 Experience with porcine thymic transplantation in baboonsTransplantation Proceedings.  32:1048. 2000
    2000 Increases in autologous hematopoietic progenitors in the blood of baboons following irradiation and treatment with porcine stem cell factor and interleukin-3Transplantation Proceedings.  32:1045-1046. 2000
    2000 Induction of mixed hematopoietic chimerism in the pig-to-baboon modelTransplantation Proceedings.  32:1101. 2000
    2000 Injection of porcine anti-idiotypic antibodies to primate anti-Gal antibodies leads to active inhibition of serum cytotoxicity in a baboonTransplantation Proceedings.  32:1102. 2000
    2000 Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: Experience with 275 aphereses in baboonsTransplantation Proceedings.  32:860. 2000
    2000 Von willebrand factor concentration, multimeric patterns, and cleaving protease activity in baboons undergoing xenogeneic peripheral blood stem cell transplantationTransplantation Proceedings.  32:990. 2000
    2000 Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points: A meta-analysisIndian Journal of Urology.  16:1123-1133. 2000
    2000 Oesophageal syncopeBioorganicheskaia khimiia.  82:249-253. 2000
    2000 High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral responseTransplantation.  69:2296-2304. 2000
    2000 Gene therapy and transplantationTransplantation.  69:1995-1999. 2000
    2000 An approach to the control of disease transmission in pig-to-human xenotransplantationXenotransplantation.  7:143-155. 2000
    2000 Xenotransplantation (multiple letters)Journal of Refractive Surgery.  320:868-869. 2000
    2000 Anti-Galα1-3Gal antibody levels in organ transplant recipients receiving immunosuppressive therapyTransplantation.  69:914-917. 2000
    2000 Xenogeneic and allogeneic skin grafting after retrovirus-mediated SLA Class II DR gene transfer in baboonsTransplantation Proceedings.  32:289-290. 2000
    2000 Venular thrombosis is the key event in the pathogenesis of antibody- mediated cardiac rejectionXenotransplantation.  7:31-41. 2000
    2000 Acute humoral xenograft rejection: Destruction of the microvascular capillary endothelium in pig-to-nonhuman primate renal graftsLaboratory Investigation.  80:815-830. 2000
    2000 Decreased graft-versus-host disease after haplotype mismatched bone marrow allografts in miniature swine following interleukin-2 treatmentmSystems.  25:47-52. 2000
    2000 Disordered regulation of coagulation and platelet activation in xenotransplantationXenotransplantation.  7:166-176. 2000
    2000 Pharmacotherapeutic agents in xenotransplantationExpert Opinion on Pharmacotherapy.  1:757-769. 2000
    2000 Report of the xenotransplantation advisory committee of the international society for heart and lung transplantation: The present status of xenotransplantation and its potential role in the treatment of end-stage cardiac and pulmonary diseasesThe Journal of heart transplantation.  19:1125-1165. 2000
    2000 Xenotransplantation. This new form of treatment might benefit millions.Journal of Refractive Surgery.  320:868. 2000
    2000 Xenotransplantation: The challenge to current psychosocial attitudesJournal of Transplant Coordination.  10:217-225. 2000
    1999 Peripheral blood progenitor cell mobilization and leukapheresis in pigsLaboratory Animal Science.  49:645-649. 1999
    1999 Xenoreactive natural antibodiesJournal of wilderness medicine.  56:1001-1007. 1999
    1999 Pig xenogeneic antigen modification with green coffee bean α- galactosidaseXenotransplantation.  6:238-248. 1999
    1999 Different responses of human anti-HLA and anti-αgal antibody to long- term intravenous immunoglobulin therapyXenotransplantation.  6:181-186. 1999
    1999 The problem of anti-pig antibodies in pig-to-primate xenografting: Current and novel methods of depletion and/or suppression of production of anti-pig antibodiesXenotransplantation.  6:157-168. 1999
    1999 Major carbohydrate epitopes in tissues of domestic and African wild animals of potential interest for xenotransplantation researchXenotransplantation.  6:79-89. 1999
    1999 Transfer of swine major histocompatibility complex class II genes into autologous bone marrow cells of baboons for the induction of tolerance across xenogeneic barriersTransplantation.  67:1119-1128. 1999
    1999 David Kempton Cartwright Cooper, MD: A conversation with the editorTranslational Oncology.  83:1253-1262. 1999
    1999 Long-term discordant xenogeneic (porcine-to-primate) bone marrow engraftment in a monkey treated with porcine-specific growth factorsTransplantation.  67:972-977. 1999
    1999 Serum cytotoxicity to pig cells and anti-αGal antibody level and specificity in humans and baboonsTransplantation.  67:658-665. 1999
    1999 Brain death and its influence on donor organ quality and outcome after transplantationTransplantation.  67:343-348. 1999
    1999 Effect of pig-specific cytokines on mobilization of hematopoietic progenitor cells in pigs and on pig bone marrow engraftment in baboonsXenotransplantation.  6:17-27. 1999
    1999 Intravenous synthetic αgal saccharides delay hyperacute rejection following pig-to-baboon heart transplantationXenotransplantation.  6:36-42. 1999
    1999 Lack of variation in αgal expression on lymphocytes in miniature swine of different genotypesXenotransplantation.  6:43-51. 1999
    1999 Physiologic changes following brain deathTransplantation Proceedings.  31:1001-1002. 1999
    1999 Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorptionTransplantation.  67:18-30. 1999
    1999 A reliable, rapid and inexpensive two-color fluorescence assay to monitor serum cytotoxicity in xenotransplantationJournal of Immunological Methods.  222:31-44. 1999
    1999 Anti-Gal, alpha-Gal epitopes, and xenotransplantation.Subcellular Biochemistry.  32:229-257. 1999
    1999 Xenogeneic thymic transplantation in a pig-to-nonhuman primate modelTransplantation Proceedings.  31:957. 1999
    1999 Xenotransplantation--state of the art--update 1999.Frontiers in Bioscience.  4. 1999
    1998 Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenograftsTransplantation.  66:1439-1450. 1998
    1998 Comparison of Bile Chemistry between Humans, Baboons, and Pigs: Implications for Clinical and Experimental Liver XenotransplantationLaboratory Animal Science.  48:197-200. 1998
    1998 Discordant organ xenotransplantation in primates: World experience and current statusTransplantation.  66:547-561. 1998
    1998 The safety of xenotransplantationTransplantation Proceedings.  30:2461-2462. 1998
    1998 Anti-Galα1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance inductionTransplantation.  66:176-182. 1998
    1998 Intravenous infusion of Galα1-3Gal oligosaccharides in baboons delays hyperacute rejection of porcine heart xenograftsTransplantation.  65:346-353. 1998
    1998 Hepatitis C status of heart transplant recipientsSurgery, gynecology & obstetrics.  12:5-10. 1998
    1998 Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galα1-3Galβ1-4βGlc-X immunoaffinity columnTransplantation.  65:172-179. 1998
    1998 Comparative histopathology of hepatic allografts and xenografts in the nonhuman primateXenotransplantation.  5:197-206. 1998
    1998 Depletion of anti-Galα1-3Gal antibody in baboons by specific α-Gal immunoaffinity columnsXenotransplantation.  5:122-131. 1998
    1998 Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti-αGal antibody in the baboonXenotransplantation.  5:274-283. 1998
    1998 Xenoantigens and xenoantibodiesXenotransplantation.  5:6-17. 1998
    1998 Xenostransplantation of cells and tissues: Application to a range of diseases, from diabetes to Alzheimer'sMolecular Medicine Today.  4:39-45. 1998
    1997 Review of literature on heart transplant recipients' return to work: predictors and outcomes.Social Work in Health Care.  26. 1997
    1997 Letter to the EditorSocial Work in Health Care.  26:87-89. 1997
    1997 Delayed xenograft rejection of pig-to-baboon cardiac transplants after cobra venom factor therapyTransplantation.  64:1255-1261. 1997
    1997 Xenoantigens and xenoantibodies: Their modificationWorld Journal of Surgery.  21:901-906. 1997
    1997 Primary bronchogenic carcinoma in recipients of heart transplantsTransplant International.  10:312-316. 1997
    1997 Women's health status and use of health services in a rapidly growing peri-urban area of South AfricaSocial Science and Medicine.  45:149-157. 1997
    1997 Clinical xenotransplantation: Past, present and futureBioorganicheskaia khimiia.  79:13-19. 1997
    1997 Anti-GAL IgG antibodies in sera of newborn humans and baboons and its significance in pig xenotransplantationTransplantation.  63:182-186. 1997
    1997 Legal implications of xenotransplantationXenotransplantation.  4:132-139. 1997
    1997 Returning to work after heart transplantation: A replicationResearch on Social Work Practice.  7:370-377. 1997
    1997 Ultrastructure changes associated with brain death in the human donor heartTransplant International.  10:24-32. 1997
    1997 Xenotransplantation.Scientific American.  277:54-59. 1997
    1996 Manipulation of the anti-αGal antibody-αGal epitope system in experimental discordant xenotransplantationXenotransplantation.  3:102-111. 1996
    1996 In vivo immunoadsorption of antipig antibodies in baboons using a specific Galα1-3Gal columnTransplantation.  62:1379-1384. 1996
    1996 Glycans derived from porcine stomach mucin are effective inhibitors of natural anti-α-galactosyl antibodies in vitro and after intravenous infusion in baboonsTransplantation.  62:1324-1331. 1996
    1996 Monoclonal antiidiotypic antibodies neutralize cytotoxic effects of anti-αGal antibodiesTransplantation.  62:837-843. 1996
    1996 A histopathologic grading system of hyperacute (humoral, antibody- mediated) cardiac xenograft and allograft rejectionThe Journal of heart transplantation.  15:804-817. 1996
    1996 Cobra venom factor stimulates anti-α-galactose antibody production in baboons: Implications for pig-to-human xenotransplantationTransplantation.  62:678-681. 1996
    1996 A comparison of transplant patient and social worker attitudes in regard to transplant patient psychosocial selection criteria, role expectations, and communication styleSocial Work in Health Care.  23:39-52. 1996
    1996 How many endomyocardial biopsies are necessary in the first year after heart transplantation?Transplant International.  9:243-247. 1996
    1996 Characterization of baboon class I major histocompatibility molecules: Implications for baboon-to-human xenotransplantationTransplantation.  61:989-996. 1996
    1996 Xenotransplantation: Benefits, risks and regulationBioorganicheskaia khimiia.  78:92-96. 1996
    1996 The existence of coronary artery disease in a potential heart donor.Journal of Transplant Coordination.  6:4. 1996
    1996 The reducing end of αGal oligosaccharides contributes to their efficiency in blocking natural antibodies of human and baboon seraTransplant International.  9:98-101. 1996
    1996 Cardiac transplantation in patients aged 60 years or older.Journal of the Oklahoma State Medical Association.  89:22-25. 1996
    1996 Cervical cytology screening--knowledge, attitudes and practice in a peri-urban settlement.South African Medical Journal.  86:1185-1188. 1996
    1996 Ethical aspects of xenotransplantation of current importanceXenotransplantation.  3:264-274. 1996
    1996 Investigation of the anti-complement agents, FUT-175 and K76COOH, in discordant xenotransplantationXenotransplantation.  3:237-245. 1996
    1996 Organ transplants [1]Nature.  379:578. 1996
    1996 Ratites (ostrich, emu) as potential heart donors for humans: Immunologic, anatomic, and physiologic considerationsXenotransplantation.  3:252-259. 1996
    1996 The potential role of thyroid hormone substitutes in cardiac surgery and transplantationThe AustralAsian Journal of Cardiac and Thoracic Surgery.  5:40-46. 1996
    1996 Xenotransplantation--state of the art.Frontiers in Bioscience.  1. 1996
    1995 Newborn baboon serum anti-αgalactosyl antibody levels and cytotoxicity to cultured pig kidney (PK15) cellsTransplantation.  60:520-521. 1995
    1995 Secondary organ allografting after a primary “bridging” xenotransplantTransplantation.  60:19-22. 1995
    1995 A comparison of organ transplant patient and professional staff attitudesInternational Journal of Rehabilitation and Health.  1:167-178. 1995
    1995 Auxiliary liver allografting and xenografting in the nonhuman primateTransplantation.  59:1670-1676. 1995
    1995 Alternatives to human heart replacementInternational Journal of Disaster Resilience in the Built Environment.  10:218-222. 1995
    1995 Atypical clostridium difficile colitis in a heart transplant recipientThe Journal of heart transplantation.  14:606-607. 1995
    1995 Detection, immunoabsorption, and inhibition of cytotoxic activity of anti‐αGal antibodies using newly developed substances with synthetic Gal α1–3Gal disaccharide epitopesXenotransplantation.  2:98-106. 1995
    1995 Failure of intrathymic inoculation of donor-specific splenocytes to prolong cardiac or renal allograft survival in dogsTransplant Immunology.  3:39-44. 1995
    1995 Induction therapy with cyclosporine without cytolytic agents results in a low incidence of acute rejection without significant renal impairment in heart transplant patientsSurgery, gynecology & obstetrics.  9:334-339. 1995
    1995 Inhibition of human anti‐αGal IgG by oligosaccharides derived from porcine stomach mucinXenotransplantation.  2:279-288. 1995
    1995 Screening of baboons as potential liver donors for humansXenotransplantation.  2:244-252. 1995
    1995 Vladimir DemikhovSchizophrenia Bulletin.  59:1628. 1995
    1994 Cardiac allotransplantation across the ABO-blood group barrier by the neutralization of preformed antibodies: The baboon as a model for the humanLaboratory Animal Science.  44:121-124. 1994
    1994 Monomorphic and polymorphic carbohydrate antigens on pig tissues: implications for organ xenotransplantation in the pig-to-human modelTransplant International.  7:405-413. 1994
    1994 Evidence that intravenously administered a-galactosyl carbohydrates reduce baboon serum cytotoxicity to pig kidney cells (pk15) and transplanted pig heartsTransplantation.  58:330-337. 1994
    1994 Heart transplantation for giant cell myocarditis [1]The Journal of heart transplantation.  13:555. 1994
    1994 Medication noncompliance and its relationship to financial factors after heart transplantation [2]The Journal of heart transplantation.  13:930. 1994
    1994 Oligosaccharides and Discordant XenotransplantationImmunological Reviews.  141:31-58. 1994
    1994 Protection of pig kidney (pk15) cells from the cytotoxic effect of anti-pig antibodies by α-galactosyl oligosaccharidesTransplantation.  57:959-963. 1994
    1994 Study of the relative incidences of psychosocial factors before and after heart transplantation and the influence of posttransplantation psychosocial factors on heart transplantation outcomeThe Journal of heart transplantation.  13:424-432. 1994
    1994 Survival following organ transplantation in an Oklahoma institution, 1985-1993.Journal of the Oklahoma State Medical Association.  87:506-508. 1994
    1994 The pig as a potential organ donor for man: A study of potentially transferable disease from donor pig to recipient manTransplantation.  57:694-703. 1994
    1994 Variability of anti‐αGal antibodies in human serum and their relation to serum cytotoxicity against pig cellsXenotransplantation.  1:58-65. 1994
    1993 Binding and specificity of major immunoglobulin classes of preformed human anti-pig heart antibodiesTransplant International.  6:351-353. 1993
    1993 Genetically engineered pigsLancet.  342:682-683. 1993
    1993 A successful regimen to reduce cytomegalovirus disease in heart transplant patientsTransplantology: Journal of Cell and Organ Transplantation.  4:47-53. 1993
    1993 A suggested technique for 'orthotopic' heart transplantation in a patient with situs inversusTexas Heart Institute Journal.  20:281-284. 1993
    1993 Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantationTransplantation.  56:1433-1442. 1993
    1993 Early detection of de novo hepatitis C infection in patients after liver transplantation by reverse transcriptase polymerase chain reactionSurgery.  114:442-448. 1993
    1993 Identification of α-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in manTransplant Immunology.  1:198-205. 1993
    1993 Methyl methacrylate plate to prevent compression after heart transplantationSchizophrenia Bulletin.  55:1242-1243. 1993
    1993 Returning to work after heart transplantationThe Journal of heart transplantation.  12:46-54. 1993
    1993 Specific intravenous carbohydrate therapy: A new concept in inhibiting antibody-mediated rejection - Experience with ABO-incompatible cardiac allografting in the baboonTransplantation.  56:769-777. 1993
    1993 Task force 6: Future developmentsJournal of the American College of Cardiology.  22:54-64. 1993
    1993 Transplantation using donor hearts from patients with circulatory arrestSchizophrenia Bulletin.  55:811-812. 1993
    1992 Is xenotransplantation a realistic clinical option?Transplantation Proceedings.  24:2393-2396. 1992
    1992 Angina pectoris in patients with cardiac transplants [1]Surgery, gynecology & obstetrics.  6:139-140. 1992
    1992 Cytomegalovirus disease in heart transplant patientsTransplantation.  53:1167-1168. 1992
    1992 Donor organ availability.Journal of the Oklahoma State Medical Association.  85:111-114. 1992
    1992 Donor-heart evaluation by monitoring the left ventricular pressure-volume relationship: Clinical observationsThe Journal of heart transplantation.  11:685-692. 1992
    1992 Enzyme‐linked immunosorbent assay for the detection of substances that carry blood group A specificityTransfusion.  32:618-623. 1992
    1992 Invited letter concerning: Changes in plasma-free thyroid hormones during cardiopulmonary bypass [1]Journal of Thoracic and Cardiovascular Surgery.  104:526-527. 1992
    1992 Nonhemic prime in cardiopulmonary bypassSchizophrenia Bulletin.  53:180. 1992
    1992 Organ transplantation in India.The Journal of heart transplantation.  11:164. 1992
    1992 Prevention of loss of vertebral bone density in heart transplant patientsThe Journal of heart transplantation.  11:959-964. 1992
    1992 Social rehabilitation and return to work after cardiac transplantation—a multicenter surveyTransplantation.  53:433-438. 1992
    1992 The assessment of the results of heart transplantation.The Journal of heart transplantation.  11:165-166. 1992
    1992 The chacma baboon as an organ donor for manTransplantation.  53:1380-1381. 1992
    1991 Risk of endocarditis in donor hearts.The Journal of heart transplantation.  10:618. 1991
    1991 Histopathology of hyperacute rejection of the heart: Experimental and clinical observations in allografts and xenograftsThe Journal of heart transplantation.  10:223-234. 1991
    1991 Human cancer prostaglandins and patient survival.Ot Practice.  21 B:875-878. 1991
    1991 Successful management of symptomatic cytomegalovirus disease with ganciclovir after heart transplantationThe Journal of heart transplantation.  10:656-663. 1991
    1991 The gastrointestinal management of patients undergoing heart transplantation.Journal of the Oklahoma State Medical Association.  84:557-562. 1991
    1991 Triiodothyronine in the recovery of stunned myocardium in dogsSchizophrenia Bulletin.  51:10-17. 1991
    1990 Accelerated cardiac allograft rejection associated with administration of liver cell extract in the baboonTransplantation Proceedings.  22:1966-1969. 1990
    1990 Changes in triiodothyronine during cardiopulmonary bypass: A clinical problem? (I: Reply)Journal of Thoracic and Cardiovascular Surgery.  100:465. 1990
    1990 Clinical survey of heart transplantation between ABO blood group - incompatible recipients and donorsThe Journal of heart transplantation.  9:376-381. 1990
    1990 Cytoimmunologic monitoring after heart and heart-lung transplantationThe Journal of heart transplantation.  9:133-135. 1990
    1990 Effect of pharmacologic immunosuppression on donor heart survival in a closely related nonhuman primate xenograft modelTransplantation Proceedings.  22:1086-1087. 1990
    1990 Experience with cardiorespiratory support devices in patients undergoing heart and heart-lung transplantation.Journal of the Oklahoma State Medical Association.  83:449-453. 1990
    1990 Improved cardiac allograft function following triiodothyronine therapy to both donor and recipientTransplantation.  49:311-316. 1990
    1989 Xenotransplantation and AIDS: Retroviral prevalence in the non-human primate donorJournal of Organ Dysfunction.  4:188-190. 1989
    1989 Optimalization of immunosuppression after xenogeneic heart transplantation in primatesThe Journal of heart transplantation.  8:200-208. 1989
    1989 Can cardiac allografts and xenografts be transplanted across the ABO blood group barrier?Transplantation Proceedings.  21:549-550. 1989
    1989 The role of ABO blood group compatibility in heart transplantation between closely related animal species. An experimental study using the vervet monkey to baboon cardiac xenograft modelJournal of Thoracic and Cardiovascular Surgery.  97:447-455. 1989
    1989 Experience with endomyocardial biopsy in 23 patients with heart transplants.Journal of the Oklahoma State Medical Association.  82:109-111. 1989
    1989 Can cardiac allografts and xenografts be transplanted across the ABO blood group barrier?Transplantation Proceedings.  21:549-550. 1989
    1989 Diagnosis of acute cardiac rejection by changes in left ventricular volumes.Transplantation Proceedings.  21:2533. 1989
    1989 Diagnosis of acute cardiac rejection by changes in left ventricular volumesTransplantation Proceedings.  21:2533. 1989
    1989 Does central nervous system toxicity occur in transplant patients with hypocholesterolemia receiving cyclosporineThe Journal of heart transplantation.  8:221-224. 1989
    1989 Early extranuclear effect of triiodothyronine (T3) on tissue slices: Relevance to organ donor viabilityTransplantation Proceedings.  21:1263-1264. 1989
    1989 Electrocardiographic and histopathologic changes developing during experimental brain death in the baboonTransplantation Proceedings.  21:2567-2569. 1989
    1989 Inotropic effect of triiodothyronine (T3) in low cardiac output following cardioplegic arrest and cardiopulmonary bypass: An initial experience in patients undergoing open heart surgeryEuropean Journal of Cardio-Thoracic Surgery.  3:140-145. 1989
    1989 Pituitary function in brain-dead patientsTransplantation.  48:1078-1079. 1989
    1989 Right ventricular assist by a heterotopic left ventricleThe Journal of heart transplantation.  8:345-346. 1989
    1989 The pathophysiological effects of brain death on potential donor organs, with particular reference to the heartBioorganicheskaia khimiia.  71:261-266. 1989
    1989 Xenograft transplantationTransplantation.  47:408. 1989
    1989 XenotransplantationTransplantation.  47:747. 1989
    1988 Malignant fibrous histiocytoma of the heart. A case reportSouth African Medical Journal.  74:418-420. 1988
    1988 Added effects of organ (heart) storage after brain death in the experimental animalTransplantation Proceedings.  20:39-43. 1988
    1988 Effects of hormonal therapy on subsequent organ (kidney) storage in the experimental animalTransplantation Proceedings.  20:55-58. 1988
    1988 Endocrine changes and metabolic responsesTransplantation Proceedings.  20:33-38. 1988
    1988 Hemodynamic and electrocardiographic responsesTransplantation Proceedings.  20:25-28. 1988
    1988 Hormonal therapy in the brain-dead experimental animalTransplantation Proceedings.  20:51-54. 1988
    1988 Myocardial and pulmonary histopathologic changesTransplantation Proceedings.  20:29-32. 1988
    1988 Results of hormonal therapy in human brain-dead potential organ donorsTransplantation Proceedings.  20:59-62. 1988
    1988 Cardiac allotransplantation across major blood group barriers in the baboonJournal of Medical Primatology.  17:333-346. 1988
    1988 Prediction of acute cardiac rejection by changes in left ventricular volumesThe Journal of heart transplantation.  7:453-455. 1988
    1988 Added effects of organ (heart) storage after brain death in the experimental animal.Transplantation Proceedings.  20:39-43. 1988
    1988 Effects of hormonal therapy on subsequent organ (kidney) storage in the experimental animal.Transplantation Proceedings.  20:55-58. 1988
    1988 Endocrine changes and metabolic responses.Transplantation Proceedings.  20:33-38. 1988
    1988 Hemodynamic and electrocardiographic responses.Transplantation Proceedings.  20:25-28. 1988
    1988 Hormonal therapy in the brain-dead experimental animal.Transplantation Proceedings.  20:51-54. 1988
    1988 Myocardial and pulmonary histopathologic changes.Transplantation Proceedings.  20:29-32. 1988
    1988 Results of hormonal therapy in human brain-dead potential organ donors.Transplantation Proceedings.  20:59-62. 1988
    1988 Indications for heterotopic heart transplantation and report on two patients.Journal of the Oklahoma State Medical Association.  81:513-517. 1988
    1988 Assessment and selection of patients for heart transplantation.Journal of the Oklahoma State Medical Association.  81:137-140. 1988
    1988 Change from aerobic to anaerobic metabolism after brain death, and reversal following triiodothyronine therapyTransplantation.  45:32-36. 1988
    1988 Effect of triiodothyronine (T3) on myocardial high energy phosphates and lactate after ischemia and cardiopulmonary bypass: An experimental study in baboonsJournal of Thoracic and Cardiovascular Surgery.  96:600-607. 1988
    1988 Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboonHeart transplantation / International Society for Heart Transplantation.  7:238-246. 1988
    1988 Initial Experimental Experience with a “Replaceable” Cardiac Valve ProsthesisSchizophrenia Bulletin.  45:554-558. 1988
    1988 Initial experience with heart and lung transplantationTexas Heart Institute Journal.  15:3-6. 1988
    1988 Injury of myocardial conduction tissue and coronary artery smooth muscle following brain death in the baboonTransplantation.  45:964-966. 1988
    1988 Inotropic Effect of Triiodothyronine Following Myocardial Ischemia and Cardiopulmonary Bypass: An Experimental Study in PigsSchizophrenia Bulletin.  45:50-55. 1988
    1988 Surgical management of stab wounds of the chest. A 6-month prospective study of 45 consecutive cases requiring operationJournal- Royal College of Surgeons Edinburgh.  33:78-83. 1988
    1988 The effects of denervation and acute rejection on left ventricular volumes measured by radionuclide ventriculography following cardiac transplantation in the chacma baboonSeminars in Nuclear Medicine.  18:213-220. 1988
    1988 The physiological management of cardiac transplant donors and recipients using triiodothyronineTransplantation Proceedings.  20:803-805. 1988
    1988 The role of nuclear cardiology procedures in the evaluation of cardiac function following heart transplantationSeminars in Nuclear Medicine.  18:221-240. 1988
    1988 Thyroid function in human cardiac allograft donorsTransplantation.  45:671-672. 1988
    1988 Triiodothyronine therapy for heart donor and recipientThe Journal of heart transplantation.  7:370-376. 1988
    1988 Triiodothyronine therapy in the cardiac transplant recipientTransplantation Proceedings.  20:65-68. 1988
    1987 Brain death, triiodothyronine depletion, and inhibition of oxidative phosphorylation: Relevance to management of organ donorsTransplantation Proceedings.  19:4110-4111. 1987
    1987 Heart transplantation at Groote Schuur Hospital, Cape Town. Twenty years' experienceSouth African Medical Journal.  72:737-739. 1987
    1987 Is ABO compatibility essential in xenografting between closely related species?Transplantation Proceedings.  19:4437-4440. 1987
    1987 Prolongation of cardiac xenograft (vervet monkey to baboon) function by a combination of total lymphoid irradiation and immunosuppressive drug therapyTransplantation Proceedings.  19:4441-4442. 1987
    1987 Twenty years of heart transplantation at Groote Schuur HospitalHeart transplantation / International Society for Heart Transplantation.  6:317-323. 1987
    1987 Virological implications of the use of primates in xenotransplantationTransplantation Proceedings.  19:4068-4069. 1987
    1987 Cardiac allograft survival in ABO blood group incompatible baboonsTransplantation Proceedings.  19:1036-1038. 1987
    1987 Cardiac transplantation using discordant xenografts in a nonhuman primate modelTransplantation Proceedings.  19:1153-1154. 1987
    1987 Cardiac allograft survival in ABO blood group incompatible baboons.Transplantation Proceedings.  19:1036-1038. 1987
    1987 Cardiac transplantation using discordant xenografts in a nonhuman primate model.Transplantation Proceedings.  19:1153-1154. 1987
    1987 Are there indications for heterotopic heart transplantation today?Transplantation Proceedings.  19:2512-2513. 1987
    1987 Hemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donorsTransplantation.  43:852-854. 1987
    1987 Improved cardiac function following hormonal therapy in brain dead pigs: Relevance to organ donationGenome Medicine.  24:1-10. 1987
    1987 Is pulmonary ischemia a factor in the reperfusion response? An experimental study in the chacma baboon.The Journal of heart transplantation.  6:238-243. 1987
    1987 Loss of myocardial viability following hypothermic perfusion storage from contaminating trace elements in the perfusateTransplantation.  43:23-28. 1987
    1987 Pathophysiology of Pulmonary Edema Following Experimental Brain Death in the Chacma BaboonSchizophrenia Bulletin.  43:288-294. 1987
    1987 Prevention of myocardial injury by pretreatment with verapamil hydrochloride prior to experimental brain death: Efficacy in a baboon modelAssessment Update: Progress, Trends, and Practices in Higher Education.  5:11-18. 1987
    1987 Successful orthotopic heart-lung transplantation in the baboon after five hours of cold ischemia with cardioplegia and Collins' solution.The Journal of heart transplantation.  6:15-22. 1987
    1987 The value of hormonal therapy in improving organ viability in the transplant donor.Transplantation Proceedings.  19:2037-2038. 1987
    1986 Acute pulmonary rejection precedes cardiac rejection following heart-lung transplantation in a primate modelThe Journal of heart transplantation.  5:29-32. 1986
    1986 Hemodynamic and myocardial histologic and ultrastructural studies on baboons from 3 to 27 months following autotransplantation of hearts stored by hypothermic perfusion for 24 or 48 hoursThe Journal of heart transplantation.  5:122-129. 1986
    1986 Hyperacute rejection in a discordant (pig to baboon) cardiac xenograft modelThe Journal of heart transplantation.  5:411-418. 1986
    1986 Interpretation of endomyocardial biopsy after heart transplantation. Potentially confusing factorsSouth African Medical Journal.  70:789-792. 1986
    1986 Regression of Kaposi's sarcoma after reduction of immunosuppressive therapy in a heart transplant patientThe Journal of heart transplantation.  5:461-464. 1986
    1986 Value of triiodothyronine (T3) therapy to brain-dead potential organ donors.The Journal of heart transplantation.  5:486-487. 1986
    1986 Surgery in patients with heart transplants. Anaesthetic and operative considerationsSouth African Medical Journal.  70:137-142. 1986
    1986 The effects of brain death and 24 hours' storage by hypothermic perfusion on donor heart function in the pigJournal of Thoracic and Cardiovascular Surgery.  91:896-909. 1986
    1986 Acute Isolated Pulmonary Rejection Following Transplantation of the Heart and Both Lungs: Experimental and Clinical ObservationsSchizophrenia Bulletin.  42:180-184. 1986
    1986 Are there indications for heterotopic heart transplantation in 1986? A 2- to 11-year follow-up of 49 consecutive patients undergoing heterotopic heart transplantationThoracic and Cardiovascular Surgeon.  34:300-304. 1986
    1986 Brain death-induced hemodynamic changes resulting in cardiac and pulmonary injury in the baboonTransplantation Proceedings.  18:1190-1192. 1986
    1986 Endomyocardial biopsy site morphology. An experimental study in baboonsJAMA Internal Medicine.  110:622-625. 1986
    1986 Evidence of myocardial and renal functional recovery following hormonal treatment after brain deathTransplantation Proceedings.  18:613-615. 1986
    1986 Forty-eight hours hypothermic perfusion storage of pig and baboon heartsJournal of Surgical Research.  40:276-284. 1986
    1986 Hemodynamic changes, myocardial injury, and pulmonary edema induced by sympathetic activity during the development of brain death in the baboonTransplantation Proceedings.  18:609-612. 1986
    1986 Histopathologic changes at the site of endomyocardial biopsy: Potential for confusion with acute rejectionThe Journal of heart transplantation.  5:79-80. 1986
    1986 Impairment of renal slice function following brain death, with reversibility of injury by hormonal therapyTransplantation.  41:29-32. 1986
    1986 Improved function of stored hearts following hormonal therapy after brain death in pigsTransplantation Proceedings.  18:1419-1421. 1986
    1986 Prevention of Myocardial Injury During Brain Death by Total Cardiac Sympathectomy in the Chacma BaboonSchizophrenia Bulletin.  41:520-524. 1986
    1985 A successful method of administering cyclosporin A to the chacma baboonSouth African Medical Journal.  68:737-739. 1985
    1985 Does the electrocardiogram detect early acute heart rejectionThe Journal of heart transplantation.  4:546-549. 1985
    1985 Physiopathological epidemiology of tumors after transplantationCanadian Journal of Emergency Medicine.  50:153-162. 1985
    1985 Transplantation of the heart and both lungs: Experimental and clinical experience and review of the literatureSouth African Medical Journal.  67:575-580. 1985
    1985 An airlift pump device for low pressure perfusion storage of the isolated heartGenome Medicine.  22:401-408. 1985
    1985 Effects of brain death and hypothermic perfusion storage on donor heart function: An experimental studyTransplantation Proceedings.  17:231-232. 1985
    1985 Failure of pretransplant third-party and preoperative donor-specific blood transfusion to improve heterotopic cardiac allograft survival in baboonsTransplantation.  40:569-571. 1985
    1985 Further Cardiac Transplant Procedures in Patients with Heterotopic Heart TransplantsSchizophrenia Bulletin.  39:149-154. 1985
    1985 Prediction of acute cardiac rejection using radionuclide scanning to detect left ventricular volume changesTransplantation Proceedings.  17:218-220. 1985
    1984 Cyclosporin A in the management of patients with heart transplants. Initial experience at Groote Schuur HospitalSouth African Medical Journal.  66:557-562. 1984
    1984 Electrocardiographic, hemodynamic & endocrine changes occurring during experimental brain death in the Chacma baboonThe Journal of heart transplantation.  4:63-69. 1984
    1984 Preformed lymphocytotoxic antibodies disappear following cyclosporine therapyThe Journal of heart transplantation.  4:362-363. 1984
    1984 The significance of left ventricular volume measurement after heart transplantation using radionuclide techniquesThe Journal of heart transplantation.  4:206-209. 1984
    1984 Heterotopic versus orthotopic heart transplantationTransplantation Proceedings.  16:886-892. 1984
    1984 Prediction of acute cardiac rejection using radionuclide techniquesSouth African Medical Journal.  65:5-7. 1984
    1984 Cardiac Transplantation Following Storage of the Donor Heart by a Portable Hypothermic Perfusion SystemSchizophrenia Bulletin.  37:243-248. 1984
    1984 Circulatory Assistance with AllograftSchizophrenia Bulletin.  37:179. 1984
    1984 Comparison of patients with ischemic, myopathic, and rheumatic heart diseases as cardiac transplant recipientsCureus.  107:8-12. 1984
    1984 Immunosuppression in the baboon cardiac allograft model: Effects of splenectomy, bolus methylprednisolone, propranolol, high–dose azathioprine, cyclophosphamide, and a niridazole metaboliteTransplantation.  38:299-300. 1984
    1984 Lack of efficacy of high-dose verapamil in preventing brain damage in baboons and pigs after prolonged partial cerebral ischemiaAssessment Update: Progress, Trends, and Practices in Higher Education.  2:481-485. 1984
    1984 Noncompliance in heart transplant recipients: The Cape Town experienceHeart transplantation / International Society for Heart Transplantation.  3:248-253. 1984
    1984 Orthotopic and heterotopic transplantation of the heart: The Cape Town experienceBioorganicheskaia khimiia.  66:228-234. 1984
    1984 Orthotopic heart transplantation in a patient with a heterotopic heart transplantHeart transplantation / International Society for Heart Transplantation.  3:257-259. 1984
    1984 Reversal of acute rejection by cyclosporine in a heterotopic heart transplantHeart transplantation / International Society for Heart Transplantation.  3:117-120. 1984
    1984 The value of recipient heart assistance during severe acute rejection following heterotopic cardiac transplantationJournal of Cardiovascular Surgery.  25:287-295. 1984
    1984 Valve replacement in patients over 70 years of ageSouth African Medical Journal.  65:370-373. 1984
    1983 Survival after cardiac transplantation.South African Medical Journal.  64:1007. 1983
    1983 Toxoplasmosis of donor and recipient hearts after heterotopic cardiac transplantationJAMA Internal Medicine.  107:368-373. 1983
    1983 Transplantation of heartIndian Journal of Thoracic and Cardiovascular Surgery.  2:43-51. 1983
    1983 Malignant neoplasms occurring after cardiac transplantationJournal of the American Medical Association.  249:1746-1748. 1983
    1983 Malignant Neoplasms Occurring After Cardiac TransplantationJournal of the American Medical Association.  249:1746-1748. 1983
    1983 Cryptic mediastinal masses causing airways obstructionBoletin de la Asociacion Medica de Puerto Rico.  58:306-309. 1983
    1983 Factors influencing survival following heart transplantationHeart transplantation / International Society for Heart Transplantation.  3:86-91. 1983
    1983 Infectious complications after heart transplantationThorax.  38:822-828. 1983
    1983 Orthotopic allotransplantation and autotransplantation of the baboon heart following 24-hr storage by a portable hypothermic perfusion systemGenome Medicine.  20:385-394. 1983
    1983 Storage of the donor heart by a portable hypothermic perfusion system: Experimental development and clinical experienceHeart transplantation / International Society for Heart Transplantation.  2:104-110. 1983
    1983 The Surgical Technique of Heterotopic Heart TransplantationSchizophrenia Bulletin.  36:476-482. 1983
    1983 The problem of the presensitized heart transplant recipientHeart transplantation / International Society for Heart Transplantation.  2:151-154. 1983
    1983 Trends in cardiac surgery at the University of Cape Town, 1971 - 1981South African Medical Journal.  63:189-193. 1983
    1982 Changes in indications for heart transplantation. An additional argument for the preservation of the recipient's own heartJournal of Thoracic and Cardiovascular Surgery.  84:716-726. 1982
    1982 Medical, legal and administrative aspects of cadaveric organ donation in the RSASouth African Medical Journal.  62:933-938. 1982
    1982 Transplantation of the heartThe British journal of clinical practice.  36:337-345. 1982
    1982 Effect of ABO Blood-Group Antigens on Long-Term Survival after Cardiac TransplantationNew England Journal of Medicine.  307:1275-1276. 1982
    1982 Orthotopic transplantation of the baboon heart after 20 to 24 hours' preservation by continuous hypothermic perfusion with an oxygenated hyperosmolar solutionJournal of Thoracic and Cardiovascular Surgery.  83:133-140. 1982
    1982 Donor heart morphology twelve and a half years after orthotopic transplantationHeart transplantation / International Society for Heart Transplantation.  1:329-333. 1982
    1982 Emergency open-heart surgery. Experience with 100 consecutive casesScandinavian Cardiovascular Journal.  16:47-50. 1982
    1982 Heart transplantation: The South African experienceHeart transplantation / International Society for Heart Transplantation.  2:78-84. 1982
    1982 Low-dose versus high-dose steroid therapy in the prevention of acute rejection in baboon heterotopic cardiac allograftsTransplantation.  34:107-108. 1982
    1982 Technique, complications, and climncal value of endomyocardial biopsy in patients with heterotopic heart transplantsThorax.  37:727-731. 1982
    1982 The assessment and selection of patients for heterotopic heart transplantationSouth African Medical Journal.  61:575-578. 1982
    1982 The results of orthotopic and heterotopic heart transplantation at Groote Schuur Hospital, Cape Town: 1967-1981Heart transplantation / International Society for Heart Transplantation.  1:112-115. 1982
    1982 Twenty-four-hour preservation of the pig heart by a portable hypothermic perfusion systemTransplantation.  34:246-250. 1982
    1981 Clinical transplantation of the heart: A review of 13 years' personal experienceJournal of the Royal Society of Medicine.  74:670-674. 1981
    1981 Ex vivo functional evaluation of pig hearts subjected to 24 hours' preservation by hypothermic perfusionSouth African Medical Journal.  60:245-248. 1981
    1981 The present status of heterotopic cardiac transplantationJournal of Thoracic and Cardiovascular Surgery.  81:433-439. 1981
    1981 An investigation of the immunosuppressive effects of niridazole and metronidazole in rat and baboon heterotopic cardiac allograft modelsTransplantation.  31:326. 1981
    1981 Management of oesophageal perforation associated with benign stricture and hiatus hernia by oesophagoplasty and fundoplicationThorax.  36:541-542. 1981
    1981 The incidence of postoperative infection and the role of antibiotic prophylaxis in pulmonary surgery. A review of 221 consecutive patients undergoing thoracotomyPlastic Surgical Nursing.  75:154-160. 1981
    1980 A comparison of two prophylactic antibiotic regimes for open-heart surgeryJournal of Cardiovascular Surgery.  21:279-286. 1980
    1980 Long-term survival after orthotopic and heterotopic cardiac transplantationRSC Smart Materials.  281:1093-1096. 1980
    1980 Pharmacological and hypothermic inhibition of metabolism during myocardial ischaemiaThorax.  35:75. 1980
    1980 Recent experience with heart transplantationRSC Smart Materials.  281:699-702. 1980
    1979 Factors contributing to the mortality associated with open-heart surgery in infants.Progress in pediatric surgery.  13:115-129. 1979
    1979 Orthotopic heart transplantation after 16 hours ischaemiaHeart & Lung: The Journal of Acute and Critical Care.  3:295. 1979
    1979 Results of surgical correction of persistent complete atrioventricular canalThoracic and Cardiovascular Surgeon.  27:111-115. 1979
    1979 The surgical management of malignant tumours of the oesophagus and cardia: A review of the results in 292 patients treated over a 15‐year period (1961–75)Journal of Arthroplasty.  66:98-104. 1979
    1978 Collagen diseases as a cause of constrictive pericarditisThorax.  33:368-371. 1978
    1978 Incidence of postoperative infection and role of antibiotic prophylaxis in pulmonary surgeryThorax.  33:130. 1978
    1977 The Haematoxylin-basic Fuchsin-picric acid staining reaction as a test of myocardial viability in resuscitated and preserved heartsHistochemical Journal.  9:285-291. 1977
    1976 Acute massive mitral regurgitation from prosthetic valve dysfunctionHandbook of Differential Equations: Stationary Partial Differential Equations.  38:701-705. 1976
    1976 Conservative surgery for bronchial adenomataThorax.  31:44-48. 1976
    1976 The donor heart: The present position with regard to resuscitation, storage, and assessment of viabilityJournal of Surgical Research.  21:363-381. 1976
    1975 A simple method of resuscitation and short term preservation of the canine cadaver heartJournal of Thoracic and Cardiovascular Surgery.  70:896-908. 1975
    1975 Donor heart resuscitation and storageSurgery, gynecology & obstetrics.  140:621-631. 1975
    1975 Haemodynamic studies during short-term preservation of the autoperfusing heart-lung preparationJournal of Nonprofit and Public Sector Marketing.  9:753-763. 1975
    1975 Observations on ischaemic contracture of the heart ('stone heart')Journal of Nonprofit and Public Sector Marketing.  9:246-248. 1975
    1974 Resuscitation of the cadaver donor heart in the dog. I. Haemodynamic, electrocardiographic, blood chemical and histopathological changes during and after death by asphyxiaGUY'S HOSP.REP..  123:333-345. 1974
    1974 Resuscitation of the cadaver donor heart in the dog. II. A comparison of two simple techniquesGUY'S HOSP.REP..  123:347-361. 1974
    1974 Resuscitation of the cadaver donor heart in the dog. III. The influence of the agonal period on the success of resuscitationGUY'S HOSP.REP..  123:363-372. 1974
    1974 Viability assessment of the preserved heart: a brief review of current experimental techniquesGUY'S HOSP.REP..  123:131-135. 1974
    1973 Associated Carcinomata of Colon and AnusJournal of the Royal Society of Medicine.  66:686-687. 1973
    1973 Electrocardiographic prediction of unmodified rejection in heterotopic canine cardiac allograftsJournal of Nonprofit and Public Sector Marketing.  7:687-695. 1973
    1972 Transplantation of the heart.Nursing mirror and midwives journal.  134:21-23. 1972
    1972 Accidents in agricultureInjury.  3:1-8. 1972
    1971 Transplantation of the heart.Nursing Journal of India.  62:69-72. 1971
    1969 Electrocardiographic studies in the rat in physiological and pathological statesJournal of Nonprofit and Public Sector Marketing.  3:419-425. 1969
    1969 Measurement of pulmonary surfactant by du nuoy tensiometer in various physiopathological conditionsJournal of Surgical Research.  9:505-511. 1969
    1969 Transplantation of the heart and both lungs. I. Historical review.Thorax.  24:383-390. 1969
    1969 Transplantation of the heart and both lungs. II. Experimental cardiopulmonary transplantation.Thorax.  24:391-398. 1969
    1968 Experimental Development of Cardiac TransplantationRSC Smart Materials.  4:174-181. 1968

    Book

    Year Title Altmetric
    2018 Preface 2018
    2018 Recollections of pioneers in xenotransplantation research 2018
    2014 Preface 2014
    2013 Introduction.  Ed. 9781461443049.  2013

    Chapter

    Year Title Altmetric
    2018 The establishment of the International Xenotransplantation Association: The first section of The Transplantation Society.  409-418. 2018
    2018 The next great medical revolution: A cardiac surgeon's efforts to develop xenotransplantation.  27-62. 2018
    2018 Xenotransplantation: The official journal of the International Xenotransplantation Association.  401-408. 2018
    2018 Future directions in liver replacement therapy: Liver xenotransplantation.  347-378. 2018
    2014 Early clinical experience of hormonal therapy in the brain-dead potential organ donor.  191-207. 2014
    2013 Impact of brain death on storage of the heart.  283-288. 2013
    2013 Management of the brain-dead organ donor: Perspectives of the transplant coordinator.  251-261. 2013
    2013 Pathophysiology of brain death and effects of hormonal therapy in large animal models.  65-90. 2013
    2013 Thyroid hormone therapy to the recipient of a heart from a brain-dead donor.  321-331. 2013
    2012 Xenotransplantation.  391-402. 2012
    2012 Xenotransplantation of thoracic organs: Current status.  803-805. 2012

    Research Overview

  • organ transplantation, islet xenotransplantation, xenotransplantation
  • Principal Investigator On

  • Genetically-Engineered Pig Organ Transplantation into Non-human Primates  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Genetically-Engineered Pig Organ Transplantation into Non-human Primates - Administrative Supplement  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Genetically-Engineered Pig Organ Transplantation into Non-human Primates - Core A - Production of Genetically Engineered Pigs  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Genetically-Engineered Pig Organ Transplantation into Non-human Primates - Core B - Administrative  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Genetically-Engineered Pig Organ Transplantation into Non-human Primates - Project 1 - Prolonging Life-Supported Pig Kidney and Heart Graft Survival in Baboons by Suppressing Inflammation  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Genetically-Engineered Pig Organ Transplantation into Non-human Primates - Project 2 - Coagulation and Adhesion Pathway Control to Protect Lung and Liver Xenografts  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Genetically-engineered Pig Organ Transplantation into Non-human Primates - Ethical Aspects of Clinical Xenotransplantation: A National Survey of African Americans  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2016 - 2020
  • Chemistry and Biology of Heparan Sulfates  awarded by University of Maryland 2016 - 2018
  • Education And Training

  • Doctor of Medicine in Cardiovascular Disease Residency Program, University of London 1974
  • Full Name

  • David Cooper