• Dr. C. Vivek Lal is an Assistant Professor of Pediatrics at University of Alabama at Birmingham where he serves as the Director of Golden Week Small Baby Program. His lab studies various ‘omic’ mechanisms as they relate to the prediction, pathogenesis and treatment of chronic lung disease of prematurity. Dr. Lal’s particular interest lies in studying the mechanisms by which pulmonary microbiome dysbiosis and exosomes affects the inflammation in premature lungs, for which his lab is funded by National Institute of Health (NIH) and American Heart Association (AHA). His scientific contributions have been published in leading journals (JCI, Cell, Pediatric Research, etc) and he has been recognized by the American Academy of Pediatrics and Society of Pediatric Research with young investigator research awards.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2020 Human Fetal Lungs Harbor a Microbiome Signature 2020
    2020 Reply to: Bacterial DNA in Fetal Lung Samples May Be Explained by Sample Contamination. 2020
    2020 Predicting BPD: Lessons Learned From the Airway Microbiome of Preterm Infants 2020
    2020 Effects of hyperoxia on alveolar and pulmonary vascular development in germ-free mice 2020
    2020 Maternal antibiotics augment hyperoxia-induced lung injury in neonatal mice 2020
    2019 Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung 2019
    2019 Airway Microbiome and Development of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review 2019
    2019 Integrating multiomics longitudinal data to reconstruct networks underlying lung development 2019
    2018 Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory 2018
    2018 Early airway microbial metagenomic and metabolomic signatures are associated with development of severe bronchopulmonary dysplasia 2018
    2018 Genomics, microbiomics, proteomics, and metabolomics in bronchopulmonary dysplasia 2018
    2018 Mechanisms of ventilator-induced lung injury: Is the elafin in the room? 2018
    2018 The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome 2018
    2018 The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome. 2018
    2018 Iloprost attenuates hyperoxia-mediated impairment of lung development in newborn mice 2018
    2018 Transfusion-associated necrotizing enterocolitis in preterm infants: An updated meta-analysis of observational data 2018
    2018 Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants 2018
    2018 Early progressive feeding in extremely preterm infants: A randomized trial 2018
    2018 MicroRNA-145 antagonism reverses TGF-b inhibition of F508del CFTR correction in airway Epithelia 2018
    2018 Early-Onset Neonatal Sepsis with Extended Spectrum Beta-Lactamase Producing Escherichia Coli in Infants Born to South and South East Asian Immigrants: A Case Series 2018
    2017 Impact of the Neonatal Resuscitation Program–Recommended Low Oxygen Strategy on Outcomes of Infants Born Preterm 2017
    2017 Cellular and humoral biomarkers of Bronchopulmonary Dysplasia 2017
    2017 Ureaplasma infection-mediated release of matrix metalloproteinase-9 and PGP: A novel mechanism of preterm rupture of membranes and chorioamnionitis 2017
    2016 Endothelial monocyte-activating polypeptide II mediates macrophage migration in the development of hyperoxia-induced lung disease of prematurity 2016
    2016 The Airway Microbiome at Birth 2016
    2016 Regulation of alveolar septation by microRNA-489 2016
    2015 Genetic predisposition to bronchopulmonary dysplasia 2015
    2015 Biomarkers, Early Diagnosis, and Clinical Predictors of Bronchopulmonary Dysplasia 2015
    2014 Hypomagnesemia secondary to cerebrospinal fluid losses in a patient with congenital hydrocephalus 2014
    2014 Vascular mediators in chronic lung disease of infancy: Role of endothelial monocyte activating polypeptide II (EMAP II) 2014
    2013 Ephrin-B2 reverse signaling increases α5β1 integrin-mediated fibronectin deposition and reduces distal lung compliance 2013
    2012 Cerebellar hemorrhage: A major morbidity in extremely preterm infants 2012
    Necrotizing Enterocolitis (NEC): A Devastating Disease of Prematurity
    The closed eye harbors a unique microbiome in dry eye disease


    Year Title Altmetric
    2016 Pulmonary Hypertension in Bronchopulmonary Dysplasia.  259-279. 2016

    Education And Training

  • Doctor of Medicine, 2007
  • University of South Alabama, Internship 2009
  • University of South Alabama, Residency 2011
  • University of Texas Southwestern Medical Center, Postdoctoral Fellowship 2014
  • Full Name

  • Charitharth Lal