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Igor Chesnokov Ph.D.
Professor
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E-mail
ichesnokov@uab.edu
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Igor Chesnokov Ph.D.
Professor
Positions
Senior Scientist
,
Cancer Cell Biology
,
O'Neal Comprehensive Cancer Center
Professor (P)
,
Biochemistry & Molecular Genetics
,
Academic Joint Departments
2002 -
Associate Scientist (C)
,
Center for Biophysical Sciences and Engineering (CBSE)
,
School of Optometry
2008 -
Associate Professor (S)
,
Cell, Developmental and Integrative Biology (CDIB)
,
Academic Joint Departments
2012 -
Senior Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
2019 -
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2020
Humanized drosophila model of the Meier-Gorlin syndrome reveals conserved and divergent features of the Orc6 protein
2020
2018
Functional Characterization of Septin Complexes
.
Molecular Biology
. 52:137-150.
2018
2018
Functional Characterization of Septin Complexes
.
Molecular Biology
. 52:155-171.
2018
2018
Phosphorylation of Pnut in the early stages of Drosophila embryo development affects association of the septin complex with the membrane and is important for viability
2018
2017
The role of Pnut and its functional domains in Drosophila spermatogenesis
.
Russian Journal of Genetics: Applied Research / Vavilovskii Zhurnal Genetiki I Selektsii i Ekologicheskaya genetika
. 7:29-35.
2017
2015
Drosophila model of Meier-Gorlin syndrome based on the mutation in a conserved C-Terminal domain of Orc6
2015
2015
Analysis of peanut gene RNAi in drosophila oogenesis
2015
2015
Endostatin: A novel inhibitor of androgen receptor function in prostate cancer
2015
2015
Functional insight into the role of Orc6 in septin complex filament formation in Drosophila
2015
2013
A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation
.
eLife
. 2013.
2013
2013
A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation
.
eLife
. 2:e00882.
2013
2011
Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB
2011
2010
Study of DNA replication in Drosophila using cell free in vitro system
.
Cell Cycle
. 9:815-819.
2010
2009
Functional analysis of an Orc6 mutant in Drosophila
2009
2009
Drosophila Orc6 facilitates GTPase activity and filament formation of the septin complex
2009
2007
Erratum: Role of the Orc6 protein in origin recognition complex-dependent DNA binding and replication in Drosophila melanogaster (Molecular and Cellular Biology (2007) 27,8, (3143-3153))
.
Molecular and Cellular Biology
. 27:4206.
2007
2007
Role of the Orc6 protein in origin recognition complex-dependent DNA binding and replication in Drosophila melanogaster
.
Molecular and Cellular Biology
. 27:3143-3153.
2007
2003
A cytokinetic function of Drosophila ORC6 protein resides in a domain distinct from its replication activity
2003
2001
Functional analysis of mutant and wild-type Drosophila origin recognition complex
2001
1999
Assembly of functionally active Drosophila origin recognition complex from recombinant proteins
.
Genes and Development
. 13:1289-1296.
1999
1997
Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes
.
Cell
. 91:311-323.
1997
1996
Flanking sequences of an Alu source stimulate transcription in vitro by interacting with sequence-specific transcription factors
.
Journal of Molecular Evolution
. 42:30-36.
1996
1996
p53 inhibits RNA polymerase III-directed transcription in a promoter- dependent manner
.
Molecular and Cellular Biology
. 16:7084-7088.
1996
1993
Mobility of short interspersed repeats within the chimpanzee lineage
.
Journal of Molecular Evolution
. 37:566-572.
1993
1993
Phylogenetic isolation of a human alu flounder gene: Drift to new subfamily identity
.
Journal of Molecular Evolution
. 37:559-565.
1993
Book
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Year
Title
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2007
Multiple Functions of the Origin Recognition Complex
. Ed. 256.
2007
Research
Principal Investigator On
The Role of Orc6 in DNA Replication and Cytokinesis
awarded by
National Institute of General Medical Sciences/NIH/DHHS
2017 - 2021
DNA Replication and Cytokinesis
awarded by
National Institute of General Medical Sciences/NIH/DHHS
2011 - 2016
The Role of the Origin Recognition Complex in the Cell Cycle
awarded by
National Institute of General Medical Sciences/NIH/DHHS
2005 - 2012
Teaching
Teaching Activities
OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2011)
2011
OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2010)
2010
OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2009)
2009
OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2008)
2008
Background
Education And Training
Doctor of Philosophy in Biochemistry,
Saint-Petersburg State University
1988
Contact
Full Name
Igor
Chesnokov