My research is focused on the use of monoclonal antibodies that bind cancer cell surface receptors for cancer therapy in combination with chemotherapy agents, Wnt inhibitors, or radiation. This research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment. Orthotopic and metastatic breast, ovarian, and pancreatic cancer xenograft models are being used to optimize therapeutic regimens in collaboration with investigators from the Divisions of Gynecolo...
Dr. Ballesteros-Tato completed his Ph.D. in Molecular Biology at the Autonoma University of Madrid in Spain in July 2007. In his Ph.D. thesis work, he studied the role of the cell cycle inhibitor p21 and the apoptosis-inducing Fas receptor in controlling immunological tolerance in different murine and human autoimmune diseases. Beginning in March of 2008, he joined the laboratory of Dr. Troy Randall at Trudeau Institute as a postdoctoral fellow, and then later moved with Dr. Randall's lab to th...
My research is focused on the use of monoclonal antibodies that bind cancer cell surface receptors for cancer therapy in combination with chemotherapy agents, Wnt inhibitors, or radiation. This research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment. Orthotopic and metastatic breast, ovarian, and pancreatic cancer xenograft models are being used to optimize therapeutic regimens in collaboration with investigators from the Divisions of Gynecolo...
Mitchell Cohen, MD, a national leader in pediatric medicine and an internationally renowned specialist in children’s digestive disorders, is chair of the UAB Department of Pediatrics in the University of Alabama School of Medicine and physician-in-chief of Children’s of Alabama.
Cohen is a former professor of pediatrics, vice-chair for clinical affairs, and director of the Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children’s Hospital Medical Center.
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Victor Darley-Usmar received his Ph.D. at the University of Essex in England and then moved to the University of Oregon as a Post-Doctoral Fellow to pursue his interests in the structure and function of mitochondrial proteins in human disease. After a period as a lecturer in Japan and ten years as a Research Scientist in Burroughs Wellcome in London he joined UAB to establish his own research group in the Department of Pathology in 1995. He has received multiple awards for training and mentorin...
A graduate of Boston University in Boston, Massachusetts, Dr. Davis completed medical school at the University of Alabama School of Medicine (UASOM), where he also served his internship, residency, and the ABIM academic subspecialty research fellowship clinical investigator pathway in Hematology/Oncology. He is Professor of Medicine, Microbiology, and Biochemistry and Molecular Genetics in the division of Hematology/Oncology. He is board certified in Hematology.
Jessy Deshane received her PhD in Biochemistry and Molecular Genetics from University of Alabama at Birmingham under the mentorship of Dr. Anupam Agarwal. After completing her post-doctoral training in Immunology with Dr. David Chaplin, in Department of Microbiology, she joined the faculty of the Division of Pulmonary, Allergy, and Critical Care Medicine in the Department of Medicine in 2011 as an Assistant Professor.
Dr. Deshane is committed to an academic career combining basic and tr...
Wegener's granulomatosis, an anti-neutrophil cytoplasmic antibody (ANCA)-positive systemic small vessel vasculitide, is characterized by inflammatory lesions with granuloma formation in the upper and lower airways, pauci-immune glomerulonephritis, and anti-proteinase 3 autoantibodies. Although Wegener's granulomatosis is considered idiopathic, there has been substantial interest in environmental factors as either etiologic or accelerating risk factors, with Staphylococcus aureus having attracted...
Dr. Elson received his M.D. from Washington University in St. Louis, trained in Internal Medicine at New York Hospital/Cornell, then did his Gastroenterology fellowship at the University of Chicago. After doing full-time research in immunology at N.I.H., he joined the Faculty of the Division of Gastroenterology at the Medical College of Virginia. He moved to the University of Alabama at Birmingham to become Director of the Division of Gastroenterology and Hepatology, and subsequently served a...
I am originally from Southern part of India and came to Duke University to study for my Ph.D. in Biochemistry. I was very lonely at Duke and went through a major cultural shock — my English was not fluent and also, because I am a vegetarian, I didn’t know what or where to eat. I transferred to Southern Illinois University and worked with an outstanding scientist and very friendly group of graduate students. I received my Ph.D. in Biochemistry there; my project dealt with organisms and mechanisms...
Our laboratory concentrates on understanding the immune correlates of protection against HIV disease progression with a focus on cell medicated immune responses (CD4 and CD8 T cells). We are utilizing a variety of techniques in our laboratory to evaluate the quality of HIV-specific T cell responses observed in patients who represent the entire spectra of HIV disease. These assays include an in vitro HIV killing and an in vitro HIV viral suppression assay. These assays measure the actual clearanc...
Janusz H.S. Kabarowski received his B.Sc. degree in Biochemistry from University College London, UK. He was awarded a Ph.D. degree from the Leukaemia Research Fund centre at The Institute of Cancer Research (Chester Beatty Laboratories) in London in 1997. Dr. Kabarowski subsequently conducted postdoctoral research in the laboratory of Owen Witte at UCLA. Dr. Kabarowski joined the Department of Microbiology at UAB as an Assistant Professor in 2003 and has a secondary faculty appointment in the De...
John C. Kappes (b. 1957), Associate Professor of Medicine and Microbiology, completed his undergraduate studies in biology at Thomas More College (B.A. in Biology, 1981) and received his Ph.D. in Microbiology and Experimental Medicine from St. Thomas Institute in 1986. Dr. Kappes completed his postdoctoral fellowship studying the molecular pathogenesis of human immunodeficiency viruses and joined the UAB faculty in 1989.
Robert P. Kimberly, MD, a native of New Haven, Conn., received his Doctor of Medicine degree from Harvard Medical School after receiving a baccalaureate degree magna cum laude from Princeton University and a baccalaureate / master's degree from the University of Oxford, Oxford, England. Dr. Kimberly's achievements and honors include election to Phi Beta Kappa from Princeton University, a Rhodes Scholarship at Oxford University, a "First" class degree from Oxford, and election to both the America...
Robin Lorenz received her M.D., Ph.D. in Immunology from Washington University in St. Louis in 1990. She then completed her residency in Clinical Pathology at Barnes-Jewish Hospital, while also doing postdoctoral research in Gastrointestinal Biology at Washington University in St. Louis. Dr. Lorenz was hired at Washington University as an Assistant Professor of Pathology and Medicine in 1994. In addition, she served as the Medical Director of the Joint Clinical Immunology Laboratory for Barnes-J...
Frances (Fran) Lund completed her undergraduate studies in Microbiology at the University of Notre Dame (B.S., cum laude, 1987). She performed her graduate work with Dr. Ronald B. Corley in the Department of Microbiology at Duke University. She obtained her Ph.D. in Immunology in 1992 and went on to a post-doctoral immunology fellowship in Dr. Maureen Howard’s group at DNAX Research Institute in Palo Alto, CA. In 1997 she moved to the Trudeau Institute, a basic biomedical infectious disease rese...
Dr. Mountz is a Professor of Medicine and Director of the UAB Recombinant Inbred Strain Facility. Dr. Mountz is the Co-Director of the UAB Bone Center, the UAB Center for Aging, Basic Biology Component, and is a Physician at the Birmingham Veterans Administration Medical Center. Dr. Mountz is the recipient of the J. W. & Virginia Goodwin-Warren D. Blackburn, Jr. Research Chair in Rheumatology (2002) and recipient of the Max Cooper Award for Excellence in Research (2003). Dr. Mountz was designate...
Moon H. Nahm, Professor of Department of Medicine, with secondary appointment in Microbiology, obtained both his BA degree (in 1970) and MD degree (in 1974) from Washington University in St. Louis MO. In 1980, he completed both Internal Medicine and Laboratory Medicine residency training in Pathology Department, as well as completing post-doctoral research training in Microbiology Department at Washington University in St. Louis MO. He was a faculty member at Washington University in St. Louis a...
Obtained his B.S degree in Chemistry at Birzeit University in Palestine (1996), M.S degree in Bioinorganic Chemistry at Bergen University in Norway (1998; advisor: Dr. Einar Sletten), and a Ph.D degree in Bioinorganic Chemistry at Emory University in Atlanta (2002; advisor: Dr. Luigi Marzilli). His M.S. and Ph.D studies focused on studying the interactions of cisplatin, a leading anticancer drug, with DNA by using Nuclear Magnetic Resonance (NMR) and other biophysical methods. Dr. Saad's postdoc...
I am Associate Dean for Global Health in the School of Medicine, Director of the UAB Center for AIDS Research and a Professor of Medicine in the Division of Infectious Diseases. I am also the principal investigator of the CFAR Network of Integrated Clinical Systems (CNICS), an NIAID-funded National Network of EMR-collected clinical data at 8 CFAR centers that are merged for the purposes of clinical research. I am the founding director of the UAB 1917 HIV Clinic, which has pioneered treatment pro...
