My research focus is on understanding the molecular basis of cancer using integrative genomic, epigenetic and proteomic approach. Our groups translational cancer research involves transferring the basic research discoveries to develop disease detection markers of developing therapy for the identified targets. I have worked extensively in the area of solid tumor genomics, biomarker discovery, biology, and therapeutic targeting.
Our group’s research helps better understand the...
Dr. Manne obtained his M.S. (Biochemistry, Histochemistry, Parasitology, Zoonosis) and Ph.D. (energy metabolic pathways of endoparasites) degrees from Osmania University, Hyderabad, India. His postdoctoral training was in molecular immunology and vaccine development for malaria (Malaria Research Center, Delhi, India); in helicobacter infections (School of Microbiology, University of New South Wales, Sydney, Australia); and in histopathology, molecular tumor biology, and preclinical translational...
Dr. Chen received her BS degree from Fudan University and her Ph.D. from Xiamen University. She completed postdoctoral training and was appointed as a research instructor at the University of Vermont, School of Medicine. Dr. Chen joined the faculty of Department of Pathology at UAB in June 2004. She is currently Jay M McDonald, MD, Endowed Professor in Laboratory Medicine, Professor in Molecular and Cellular Pathology and Vice Chair for Faculty Development and Education; as well as a Research Ca...
Dr. Elmets major research interests focus on environmental influences on the skin and on the immune system. His research has investigated how ultraviolet light and other environmental agents interact with immunological function of the skin. Initial studies in mice showed that in vivo exposure of murine skin produced a local deficiency in the antigen presenting function of skin, thereby resulting in the preferential generation of antigen specific regulatory T-cells. Studies examining the mechanis...
My research is focused on the use of monoclonal antibodies that bind cancer cell surface receptors for cancer therapy in combination with chemotherapy agents, Wnt inhibitors, or radiation. This research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment. Orthotopic and metastatic breast, ovarian, and pancreatic cancer xenograft models are being used to optimize therapeutic regimens in collaboration with investigators from the Divisions of Gynecolo...
Dr. Cheng completed his medical education at Hunan Medical University in 1985. Later, he continued his graduate training at the Chinese Academy of Medical Sciences & Peking Union Medical College, and Hunan Medical University, where he later became a faculty member. Dr. Cheng served as vice chairman of the Center for Molecular Biology at Hunan Medical University from 1993 to 1996. He completed additional postdoctoral training at the Kimball Research Institute (New York Blood Center) and Emory Un...
Janusz H.S. Kabarowski received his B.Sc. degree in Biochemistry from University College London, UK. He was awarded a Ph.D. degree from the Leukaemia Research Fund centre at The Institute of Cancer Research (Chester Beatty Laboratories) in London in 1997. Dr. Kabarowski subsequently conducted postdoctoral research in the laboratory of Owen Witte at UCLA. Dr. Kabarowski joined the Department of Microbiology at UAB as an Assistant Professor in 2003 and has a secondary faculty appointment in the De...
Dr. Mountz is a Professor of Medicine and Director of the UAB Recombinant Inbred Strain Facility. Dr. Mountz is the Co-Director of the UAB Bone Center, the UAB Center for Aging, Basic Biology Component, and is a Physician at the Birmingham Veterans Administration Medical Center. Dr. Mountz is the recipient of the J. W. & Virginia Goodwin-Warren D. Blackburn, Jr. Research Chair in Rheumatology (2002) and recipient of the Max Cooper Award for Excellence in Research (2003). Dr. Mountz was designate...
I am a board-certified gynecologic pathologist with 21-year expertise in light-, immunofluorescence-, and high-resolution confocal-microscopy. I work as a staff pathologist at the UAB hospital and examine surgical tissues and provide the diagnoses. In my research projects, I have been involved in numerous collaborative studies and evaluated human, mouse and rat tissues. Pathologic findings have ranged from bacterial and viral infection, immune complex deposition and histopathology of female repr...
Dr. Mark H. Deierhoi joined the UAB Department of Surgery in 1986. He has been instrumental in the evolution of transplantation surgery at UAB. He currently serves in the renal transplant program. He also sees patients at the VA Hospital.
Dr. Deierhoi has served widely in his field, most notable with the Southeastern Organ Procurement Foundation assuming numerous committee and leadership roles with the foundation including presiding in 2003.
A consistently funded researcher, Dr...
I am an Associate Scientist and Clinical Investigator at the UAB Comprehensive Cancer Center. Through this role, I have access to all clinical trials being conducted at UAB for all cancer types. As an active member of the Eastern Cooperative Oncology Group (ECOG), I likewise have access to a broad array of national cooperative group clinical trials for most malignancies, including breast, colon, lung and prostate cancer among others.
I have special research interests in the areas of ...
Dr. Thannickal is Professor of Medicine and the Ben Vaughan Branscomb Chair of Medicine in Respiratory Disease at the University of Alabama at Birmingham (UAB). Following his fellowship training at Tufts University School of Medicine, he has held faculty positions at Tufts, University of Michigan and UAB, where he currently serves as director of the Division of Pulmonary, Allergy, and Critical Care Medicine. Under his leadership, the division has grown to over 65 faculty members and expanded its...
