My research is focused on the use of monoclonal antibodies that bind cancer cell surface receptors for cancer therapy in combination with chemotherapy agents, Wnt inhibitors, or radiation. This research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment. Orthotopic and metastatic breast, ovarian, and pancreatic cancer xenograft models are being used to optimize therapeutic regimens in collaboration with investigators from the Divisions of Gynecolo...
My research is focused on the use of monoclonal antibodies that bind cancer cell surface receptors for cancer therapy in combination with chemotherapy agents, Wnt inhibitors, or radiation. This research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment. Orthotopic and metastatic breast, ovarian, and pancreatic cancer xenograft models are being used to optimize therapeutic regimens in collaboration with investigators from the Divisions of Gynecolo...
