Selected Publications

Academic Article

Year Title Altmetric
2022 Therapeutic potential of human breast milk derived exosomesJournal of Nanoparticle Research.  24. 2022
2022 Achieving equity through science and integrity: dismantling race-based medicinePediatric Research.  91:1641-1644. 2022
2021 Cocaine‐Specific Effects on Exosome Biogenesis in Microglial CellsNeurochemical Research.  46:1006-1018. 2021
2021 Lipopolysaccharide Administration Alters Extracellular Vesicles in Cell Lines and Mice 2021
2021 Effects of Cocaine on Human Glial-Derived Extracellular VesiclesFrontiers in Cell and Developmental Biology.  8. 2021
2021 Human Adenovirus Serotype 3 Infection Modulates the Biogenesis and Composition of Lung Cell-Derived Extracellular VesiclesJournal of Immunology Research.  2021. 2021
2019 Alcohol exposure impacts the composition of HeLa-derived extracellular vesiclesBiomedicines.  7. 2019
2019 Effects of Pseudomonas aeruginosa on microglial-derived extracellular vesicle biogenesis and compositionPathogens.  8. 2019
2019 The role of lipopolysaccharide-induced extracellular vesicles in cardiac cell deathBiology.  8. 2019
2019 The Association of Intraventricular Hemorrhage and Acute Kidney Injury in Premature Infants from the Assessment of the Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) Study 2019
2019 Alcohol modulates the biogenesis and composition of microglia-derived exosomesBiology.  8. 2019
2019 Opioid Detoxification in Pregnancy: Systematic Review and Meta-Analysis of Perinatal OutcomesAmerican Journal of Perinatology.  36:581-587. 2019
2018 Editor’s ChoiceInnate Immunity.  24:277. 2018
2018 Human breast milk-derived exosomes attenuate cell death in intestinal epithelial cellsInnate Immunity.  24:278-284. 2018
2018 Tetraspanin blockage reduces exosome-mediated HIV-1 entryArchives of Virology.  163:1683-1689. 2018
2018 Exosome Biogenesis and Biological Function in Response to Viral Infections.Open Virology Journal.  12:134-148. 2018
2017 Differential binding of the HIV-1 envelope to phosphatidylserine receptors 2017
2017 Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cellsInternational Journal of Nanomedicine.  12:4823-4833. 2017
2017 Erythropoietin-induced cytoprotection in intestinal epithelial cells is linked to system Xc-Experimental Cell Research.  352:202-206. 2017
2016 Neonatal acute kidney injury and the risk of intraventricular hemorrhage in the very low birth weight infant 2016
2014 Neural stem cell-derived exosomes mediate viral entryInternational Journal of Nanomedicine.  9:4893-4897. 2014
2014 B-type natriuretic peptide and mortality in extremely low birth weight infants with pulmonary hypertension: A retrospective cohort analysisBMC Pediatrics.  14. 2014
2013 B-type natriuretic peptide is a biomarker for pulmonary hypertension in preterm infants with bronchopulmonary dysplasiaResearch and Reports in Neonatology.  Volume 3:33-36. 2013
2013 Histological characteristics of the fetal inflammatory response associated with neurodevelopmental impairment and death in extremely preterm infantsJournal of Pediatrics.  163. 2013
2012 Hypoxic preconditioning involves system Xc - regulation in mouse neural stem cellsStem Cell Research.  8:285-291. 2012
2012 Melatonin Induces Neuroprotection via System Xc Regulation in Neural Stem CellsJournal of stem cell research & therapy.  02. 2012
2012 Vitamin D3-induced Neuroprotection is Dependent on System Xc ActivityJournal of stem cell research & therapy.  02. 2012
2011 Cystine glutamate exchanger upregulation by retinoic acid induces neuroprotection in neural stem cellsNeuroReport.  22:598-602. 2011
2010 Erratum: Erythropoietin-induced neuroprotection requires cystine glutamate exchanger activity (Brain Research (2010) 1321 (88-95))Brain Research.  1362:160. 2010
2010 Erythropoietin-induced neuroprotection requires cystine glutamate exchanger activityBrain Research.  1321:88-95. 2010
2009 Developmental changes in circulating IL-8/CXCL8 isoforms in neonatesCytokine.  46:12-16. 2009
1999 Regulation of AMP deaminase by phosphoinositidesJournal of Biological Chemistry.  274:25701-25707. 1999
1998 Elevated adenosine monophosphate deaminase activity in Alzheimer's disease brainNeurobiology of Aging.  19:385-391. 1998


Year Title Altmetric
2018 Biological Function of Exosomes as Diagnostic Markers and Therapeutic Delivery Vehicles in Carcinogenesis and Infectious Diseases 2018

Education And Training

  • St. Louis Children's Hospital, Internship
  • St. Louis Children's Hospital, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Doctor of Medicine in Neonatal-Perinatal Medicine Residency Program, University of Alabama at Birmingham 2000
  • Doctor of Philosophy in Child / Pediatric Neurology, University of Alabama at Birmingham 1999
  • Bachelor of Science or Mathematics in Pediatrics Residency Program, University of Alabama at Birmingham 1991
  • Full Name

  • Brian Sims