| Year |
Title |
Altmetric |
| 2022
|
The regulation of DNA end resection by chromatin response to DNA double strand breaks.
Frontiers in Cell and Developmental Biology.
10.
2022
|
|
| 2022
|
A Flow Cytometry-Based Method for Analyzing DNA End Resection in G0- And G1-Phase Mammalian Cells.
Bio-protocol.
12.
2022
|
|
| 2022
|
DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells.
eLife.
11.
2022
|
|
| 2022
|
A Whole Genome CRISPR/Cas9 Screening Approach for Identifying Genes Encoding DNA End-Processing Proteins.
Methods in Molecular Biology.
2444:15-27.
2022
|
|
| 2021
|
The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining.
DNA Repair.
108.
2021
|
|
| 2021
|
DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G0 cells
2021
|
|
| 2021
|
RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T-cell-dependent antitumor immunity
2021
|
|
| 2021
|
Role of 53BP1 in end protection and DNA synthesis at DNA breaks.
Genes and Development.
35:1356-1368.
2021
|
|
| 2021
|
LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells.
eLife.
10.
2021
|
|
| 2021
|
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination.
Journal of Experimental Medicine.
218.
2021
|
|
| 2021
|
LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells
2021
|
|
| 2020
|
DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner.
Nature Communications.
11.
2020
|
|
| 2020
|
Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development.
iScience.
23.
2020
|
|
| 2020
|
Erratum: The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells (Molecular Cell (2018) 69(5) (879–892.e5), (S1097276518300601), (10.1016/j.molcel.2018.01.031)).
Molecular Cell.
77:1153.
2020
|
|
| 2020
|
DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes.
Cell Cycle.
19:67-83.
2020
|
|
| 2019
|
Regional gene repression by DNA double-strand breaks in G1 phase cells.
Molecular and Cellular Biology.
39.
2019
|
|
| 2019
|
At the intersection of DNA damage and immune responses.
Nature Reviews Immunology.
19:231-242.
2019
|
|
| 2019
|
XLF and H2AX function in series to promote replication fork stability
2019
|
|
| 2018
|
A Path(way) to Keeping Your Synapses on an Even Keel.
Neuron.
100:1013-1014.
2018
|
|
| 2018
|
Cell circuits between B cell progenitors and IL-7+mesenchymal progenitor cells control B cell development.
Journal of Experimental Medicine.
215:2586-2599.
2018
|
|
| 2018
|
Erratum for Franco et al., “A novel secreted protein, myr1, is central to toxoplasma’s manipulation of host cells” (mBio, (2018) 7(1), e02231-15, 10.1128/mBio.02231-15).
mBio.
9.
2018
|
|
| 2018
|
High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining.
SLAS Discovery.
23:624-633.
2018
|
|
| 2018
|
MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
Molecular Cell.
71:332-342.e8.
2018
|
|
| 2018
|
The histone chaperone ASF1 regulates the activation of ATM and DNA-PKcs in response to DNA double-strand breaks.
Cell Cycle.
17:1413-1424.
2018
|
|
| 2018
|
The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells.
Molecular Cell.
69:879-892.e5.
2018
|
|
| 2018
|
Corrected and republished from: BCL11A is a critical component of a transcriptional network that activates RAG expression and V(D)J recombination.
Molecular and Cellular Biology.
38.
2018
|
|
| 2017
|
Retraction: "The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination." [Molecular and Cellular Biology, 33, 9, (2013), (1768-1781)] doi: 10.1128/MCB.00987-12.
Molecular and Cellular Biology.
37.
2017
|
|
| 2017
|
A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.
eLife.
6.
2017
|
|
| 2017
|
Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes.
Cell Cycle.
16:286-295.
2017
|
|
| 2016
|
DNA Breaks and End Resection Measured Genome-wide by End Sequencing.
Molecular Cell.
63:898-911.
2016
|
|
| 2016
|
Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies.
Blood.
128:783-793.
2016
|
|
| 2016
|
Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses.
Molecular Biology of the Cell.
27:1332-1345.
2016
|
|
| 2016
|
RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.
Journal of Experimental Medicine.
213:209-223.
2016
|
|
| 2016
|
A novel secreted protein, MYR1, is central to Toxoplasma’s manipulation of host cells.
mBio.
7.
2016
|
|
| 2015
|
DNA damage responses: Beyond double-strand break repair.
Current Biology.
25:R45-R46.
2015
|
|
| 2015
|
Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency.
Journal of Allergy and Clinical Immunology.
136:140-150.e7.
2015
|
|
| 2014
|
HCoDES Reveals Chromosomal DNA End Structures with Single-Nucleotide Resolution.
Molecular Cell.
56:808-818.
2014
|
|
| 2014
|
ATM deficiency: Revealing the pathways to cancer.
Cell Cycle.
13:2992.
2014
|
|
| 2014
|
Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection.
Molecular Cell.
54:1022-1033.
2014
|
|
| 2014
|
Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response.
Blood.
123:3909-3913.
2014
|
|
| 2014
|
β-Catenin induces T-cell transformation by promoting genomic instability
2014
|
|
| 2014
|
KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G1-phase lymphocytes.
Molecular and Cellular Biology.
34:2811-2821.
2014
|
|
| 2014
|
L-Myc expression by dendritic cells is required for optimal T-cell priming.
Nature.
507:243-247.
2014
|
|
| 2013
|
Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.
Molecular and Cellular Biology.
33:3568-3579.
2013
|
|
| 2013
|
Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination
2013
|
|
| 2013
|
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Cell.
153:1266-1280.
2013
|
|
| 2013
|
Cutting Edge: Cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cells.
Journal of Immunology.
190:2485-2489.
2013
|
|
| 2013
|
DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.
BMC Genomics.
14.
2013
|
|
| 2013
|
The Ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements.
Journal of Experimental Medicine.
210:233-239.
2013
|
|
| 2013
|
The bcl11a transcription factor directly activates RAG gene expression and V(D)J recombination.
Molecular and Cellular Biology.
33:1768-1781.
2013
|
|
| 2012
|
Integrated signaling in developing lymphocytes: The role of DNA damage responses.
Cell Cycle.
11:4129-4134.
2012
|
|
| 2012
|
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Nature Immunology.
13:1092-1100.
2012
|
|
| 2012
|
Loss of ATM kinase activity leads to embryonic lethality in mice
2012
|
|
| 2012
|
Redundant and nonredundant functions of ATM and H2AX in αβ T-lineage lymphocytes.
Journal of Immunology.
189:1372-1379.
2012
|
|
| 2012
|
The response to and repair of RAG-mediated DNA double-strand breaks.
Annual Review of Immunology.
30:175-202.
2012
|
|
| 2012
|
Lymphocyte Development: Integration of DNA Damage Response Signaling.
Advances in Immunology.
116:175-204.
2012
|
|
| 2012
|
Preparing targets for V(D)J recombinase: Transcription paves the way.
Journal of Immunology.
188:7-9.
2012
|
|
| 2012
|
RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation.
Journal of Experimental Medicine.
209:11-17.
2012
|
|
| 2011
|
Regulation of TCRβ allelic exclusion by gene segment proximity and accessibility.
Journal of Immunology.
187:6374-6381.
2011
|
|
| 2011
|
Repair of chromosomal RAG-mediated DNA breaks by mutant RAG proteins lacking phosphatidylinositol 3-like kinase consensus phosphorylation sites.
Journal of Immunology.
187:1826-1834.
2011
|
|
| 2011
|
Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways In Vivo.
PLoS One.
6.
2011
|
|
| 2011
|
Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination.
Cell Cycle.
10:1928-1935.
2011
|
|
| 2011
|
Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair
2011
|
|
| 2011
|
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes (Nature 469 (2010) (245-249)).
Nature.
472:247.
2011
|
|
| 2011
|
Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation
2011
|
|
| 2011
|
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Nature.
469:245-250.
2011
|
|
| 2010
|
Erratum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci (Nature Immunology (2009) 10 (655-664)).
Nature Immunology.
11:356.
2010
|
|
| 2010
|
Erratum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci (Nature Immunology (2009) 10 (655-664)).
Nature Immunology.
11:355-356.
2010
|
|
| 2010
|
Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex.
Nature Immunology.
11:207-215.
2010
|
|
| 2009
|
Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis
2009
|
|
| 2009
|
Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination.
Journal of Experimental Medicine.
206:2625-2639.
2009
|
|
| 2009
|
Erratum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci (Nature Immunology (2009) vol. 10 (655-664)).
Nature Immunology.
10:1034.
2009
|
|
| 2009
|
Novel roles for A-type lamins in telomere biology and the DNA damage response pathway
2009
|
|
| 2009
|
Chimeric IgH-TCR/ translocations in T lymphocytes mediated by RAG.
Cell Cycle.
8:2408-2412.
2009
|
|
| 2009
|
Intrathymic proliferation wave essential for Vα14+ natural killer T cell development depends on c-Myc
2009
|
|
| 2009
|
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.
Nature Immunology.
10:655-664.
2009
|
|
| 2009
|
Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin.
Molecular Cell.
34:298-310.
2009
|
|
| 2009
|
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Journal of Experimental Medicine.
206:669-679.
2009
|
|
| 2009
|
Functional overlap in the cis-acting regulation of the V(D)J recombination at the TCRβ locus.
Molecular Immunology.
46:321-326.
2009
|
|
| 2008
|
Collateral Damage from Antigen Receptor Gene Diversification.
Cell.
135:1009-1012.
2008
|
|
| 2008
|
DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes.
Nature.
456:819-824.
2008
|
|
| 2008
|
53BP1 facilitates long-range DNA end-joining during V(D)J recombination.
Nature.
456:529-533.
2008
|
|
| 2008
|
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.
Nature.
456:259-263.
2008
|
|
| 2008
|
Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining.
Journal of Immunology.
181:2620-2625.
2008
|
|
| 2008
|
Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse.
European Journal of Immunology.
38:342-349.
2008
|
|
| 2007
|
SWI-SNF: Promoter of accessibility.
Nature Immunology.
8:795-796.
2007
|
|
| 2007
|
ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes.
Cell.
130:63-75.
2007
|
|
| 2007
|
Developmental stage-specific regulation of TCR-α-chain gene assembly by intrinsic features of the TEA promoter.
Journal of Immunology.
179:449-454.
2007
|
|
| 2007
|
γ-Herpesvirus Kinase Actively Initiates a DNA Damage Response by Inducing Phosphorylation of H2AX to Foster Viral Replication.
Cell Host and Microbe.
1:275-286.
2007
|
|
| 2007
|
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes.
Journal of Experimental Medicine.
204:1371-1381.
2007
|
|
| 2006
|
Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help.
Journal of Experimental Medicine.
203:1985-1998.
2006
|
|
| 2006
|
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.
Nature.
442:466-470.
2006
|
|
| 2006
|
Selective requirement of p38α MAPK in cytokine-dependent, but not antigen receptor-dependent, Th1 responses.
Journal of Immunology.
176:4616-4621.
2006
|
|
| 2006
|
Proteasome activator PA200 is required for normal spermatogenesis.
Molecular and Cellular Biology.
26:2999-3007.
2006
|
|
| 2005
|
Revision of T cell receptor α chain genes is required for normal T lymphocyte development
2005
|
|
| 2005
|
Lymphocyte antigen receptor gene assembly: Multiple layers of regulation.
Immunologic Research.
32:253-258.
2005
|
|
| 2005
|
Chromosomal excision of TCRδ chain genes is dispensable for αβ T cell lineage commitment.
International Immunology.
17:225-232.
2005
|
|
| 2005
|
Intra- and inter-allelic ordering of T cell receptor β chain gene assembly.
European Journal of Immunology.
35:964-970.
2005
|
|
| 2005
|
MAPK p38α is dispensable for lymphocyte development and proliferation.
Journal of Immunology.
174:1239-1244.
2005
|
|
| 2005
|
Regulation of T cell receptor β allelic exclusion at a level beyond accessibility.
Nature Immunology.
6:189-197.
2005
|
|
| 2004
|
Regulation of T-cell receptor β-chain gene assembly by recombination signals: The beyond 12/23 restriction.
Immunological Reviews.
200:36-43.
2004
|
|
| 2003
|
The B12/23 Restriction Is Critically Dependent on Recombination Signal Nonamer and Spacer Sequences.
Journal of Immunology.
171:6604-6610.
2003
|
|
| 2003
|
T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation.
Nature Medicine.
9:1318-1322.
2003
|
|
| 2003
|
T cell receptor CDR3 loop length repertoire is determined primarily by features of the V(D)J recombination reaction.
European Journal of Immunology.
33:1568-1575.
2003
|
|
| 2003
|
T cell receptor (TCR) α/δ locus enhancer identity and position are critical for the assembly of TCR δ and a variable region genes
2003
|
|
| 2003
|
Cutting edge: Targeting of Vβ to Dβ rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors.
Journal of Immunology.
170:5-9.
2003
|
|
| 2002
|
Analysis of the complex genomic structure of Bcl-x and its relationship to Bcl-xγ expression after CD28-dependent costimulation.
Molecular Immunology.
39:45-55.
2002
|
|
| 2002
|
Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo.
Journal of Immunology.
169:1837-1843.
2002
|
|
| 2002
|
Green fluorescent protein-glucocorticoid receptor knockin mice reveal dynamic receptor modulation during thymocyte development.
Journal of Immunology.
169:1309-1318.
2002
|
|
| 2002
|
T cell costimulation through CD28 depends on induction of the Bcl-xγ isoform: Analysis of Bcl-xγ-deficient mice.
Journal of Experimental Medicine.
196:87-95.
2002
|
|
| 2002
|
Allelic exclusion at the TCRβ locus.
Current Opinion in Immunology.
14:230-234.
2002
|
|
| 2002
|
Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination.
Journal of Experimental Medicine.
195:309-316.
2002
|
|
| 2002
|
Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells.
Science.
295:338-342.
2002
|
|
| 2002
|
Knock-ins and conditional knockouts: In vivo analysis of glucocorticoid receptor regulation and function.
Endocrine Research.
28:545-551.
2002
|
|
| 2001
|
Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor α/δ locus.
Immunology.
104:11-18.
2001
|
|
| 2000
|
Mechanisms that direct ordered assembly of T cell receptor β locus V, D, and J gene segments
2000
|
|
| 2000
|
Cloning and functional characterization of the early-lymphocyte-specific Pb99 gene.
Molecular and Cellular Biology.
20:4405-4410.
2000
|
|
| 2000
|
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.
Nature.
405:583-586.
2000
|
|
| 1999
|
Requirement for B cell linker protein (BLNK) in B cell development.
Science.
286:1949-1954.
1999
|
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| 1999
|
Host-parasite relationships between Echinostoma caproni and RAG-2- deficient mice.
Parasitology Research.
85:337-342.
1999
|
|
| 1999
|
Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions
1999
|
|
| 1999
|
A developmental switch from TCRδ enhancer to TCRα enhancer function during thymocyte maturation.
Immunity.
10:723-733.
1999
|
|
| 1999
|
Developmental regulation of TCRδ locus accessibility and expression by the TCRδ enhancer.
Immunity.
10:503-513.
1999
|
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| 1999
|
Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion.
Immunity.
10:537-546.
1999
|
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| 1998
|
Assembly of productive T cell receptor δ variable region genes exhibits allelic inclusion.
Journal of Experimental Medicine.
188:1465-1471.
1998
|
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| 1998
|
Accessibility control of variable region gene assembly during T-cell development.
Immunological Reviews.
165:121-130.
1998
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| 1997
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Function of the TCRα enhancer in αβ and γδ T cells.
Immunity.
7:505-515.
1997
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| 1996
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Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements.
Annual Review of Immunology.
14:459-481.
1996
|
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| 1992
|
Disruption of the CD4-p56(lck) complex is required for rapid internalization of CD4
1992
|
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| 1991
|
Glycolipid-anchored form of CD4 increases intercellular adhesion but is unable to enhance T cell activation.
Journal of Immunology.
147:428-431.
1991
|
|
| 1990
|
Human immunodeficiency virus infection is efficiently mediated by a glycolipid-anchored form of CD4
1990
|
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| 1990
|
The cytoplasmic domain of CD4 is required for stable association with the lymphocyte‐specific tyrosine protein kinase p56lck.
European Journal of Immunology.
20:1397-1400.
1990
|
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| 1989
|
Requirements for modulation of the CD4 molecule in response to phorbol myristate acetate. Role of the cytoplasmic domain.
Journal of Immunology.
142:1457-1462.
1989
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| 1989
|
The biologic roles of CD2, CD4, and CD8 in T-cell activation..
Annual Review of Immunology.
7:579-599.
1989
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| 1988
|
Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.
Journal of Immunology.
141:3715-3717.
1988
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| 1988
|
Expression and function of CD4 in a murine T-cell hybridoma.
Nature.
328:351-353.
1988
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| 1988
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Functional Analysis of Cd2, cd4, and cd8 in t‐Cell Activation.
Annals of the New York Academy of Sciences.
532:199-206.
1988
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| 1988
|
Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule.
Journal of Immunology.
141:49-54.
1988
|
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| 1986
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Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: Histologic analysis and correlation to clinical disease.
Journal of Investigative Dermatology.
86:371-375.
1986
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| 1983
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Determination Of Pulegone In H. Pulegioides And Peppermint Oil By Thin Layer Chromatography With Densitometry.
Journal of Liquid Chromatography and Related Technologies.
6:1175-1182.
1983
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| 1983
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Separation and quantification of epinephrine, norepinephrine, and dopamine by chromatography on diphenyl thin layers.
Journal of Separation Science.
6:156-157.
1983
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| 1982
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A Comparison Of Amino Acid Separations On Silica Gel, Cellulose, And Ion Exchange Thin Layers.
Journal of Liquid Chromatography and Related Technologies.
5:1051-1068.
1982
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| 1981
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Reversed phase thin layer chromatography of phenols on chemically bonded C18 layers.
Journal of Separation Science.
4:557-560.
1981
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|
