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Brittany Lasseigne
Assistant Professor
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E-mail
bnp0001@uab.edu
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Co-investigator Network
Brittany Lasseigne
Assistant Professor
Positions
Associate Scientist
,
Experimental Therapeutics
,
O'Neal Comprehensive Cancer Center
Assistant Professor (P)
,
Cell, Developmental and Integrative Biology (CDIB)
,
Academic Joint Departments
2019 -
Associate Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
2019 -
Associate Scientist (C)
,
Informatics Institute
,
School of Medicine
2019 -
Associate Scientist (C)
,
Personalized Medicine Institute
,
School of Medicine
2019 -
Associate Scientist (C)
,
Center for Clinical and Translational Science (CCTS)
,
General Clinical Research Center
2020 -
Publications
Research
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Publications
Selected Publications
Academic Article
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Year
Title
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2020
Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases
.
American Journal of Human Genetics
. 106:632-645.
2020
2019
Non-Coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases
2019
2019
Genome sequencing for early-onset dementia: high diagnostic yield and frequent observation of multiple contributory alleles
2019
2019
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS
2019
2019
Genome sequencing for early-onset or atypical dementia: High diagnostic yield and frequent observation of multiple contributory alleles
.
Cold Spring Harbor molecular case studies
. 5.
2019
2018
The Role of DNA Methylation in Renal Cell Carcinoma
2018
2018
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
.
Neuron
. 97:1268-1283.e6.
2018
2017
Post-mortem molecular profiling of three psychiatric disorders
2017
2017
ARNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environments
.
Bioinformatics
. 33:1727-1729.
2017
2017
Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns
.
BMC Cancer
. 17.
2017
2017
Genomic regulation of invasion by STAT3 in triple negative breast cancer
.
Oncotarget
. 8:8226-8238.
2017
2017
RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature
.
Oncotarget
. 8:38668-38681.
2017
2016
Kinase gene expression profiling of metastatic clear cell renal cell carcinoma tissue identifies potential new therapeutic targets
.
PLoS ONE
. 11.
2016
2016
RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature
2016
2016
Post-mortem molecular profiling of three psychiatric disorders
2016
2016
aRNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in high performance computing environments
2016
2015
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
.
Science
. 347:1436-1441.
2015
2014
DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinoma
.
BMC Medicine
. 12.
2014
Research
Principal Investigator On
Integrating Multidimensional Genomic Data to Discover Clinically-Relevant Predictive Models
awarded by
National Human Genome Research Institute/NIH/DHHS
2019 - 2022
Using Common Fund Data to Inform Rare Disease Preclinical Models and Prioritize Drug Repurposing
awarded by
National Institute of Dental and Craniofacial Research/NIH/DHHS
2020 - 2021
Investigator On
UAB Pilot Center for Precision Animal Modeling (C-PAM)
awarded by
NIH - OFFICE OF THE DIRECTOR
2020 - 2025
UAB Pilot Center for Precision Animal Modeling (C-PAM) - Bioinformatics Section
awarded by
NIH - OFFICE OF THE DIRECTOR
2020 - 2025
Intravital Analysis of Cilia Function during Injury in the Kidney
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
2020 - 2023
Doc Sherlock: An Autonomous Relay Agent for Discovering the "Unknown Knowns" in Precision Medicine
awarded by
National Center for Advancing Translational Sciences/NIH/DHHS
2020 - 2022
Contact
Full Name
Brittany
Lasseigne