Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases.  American Journal of Human Genetics.  106:632-645. 2020
2019 Non-Coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases 2019
2019 Genome sequencing for early-onset dementia: high diagnostic yield and frequent observation of multiple contributory alleles 2019
2019 A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS 2019
2019 Genome sequencing for early-onset or atypical dementia: High diagnostic yield and frequent observation of multiple contributory alleles.  Cold Spring Harbor molecular case studies.  5. 2019
2018 The Role of DNA Methylation in Renal Cell Carcinoma 2018
2018 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.  Neuron.  97:1268-1283.e6. 2018
2017 Post-mortem molecular profiling of three psychiatric disorders 2017
2017 ARNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environments.  Bioinformatics.  33:1727-1729. 2017
2017 Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns.  BMC Cancer.  17. 2017
2017 Genomic regulation of invasion by STAT3 in triple negative breast cancer.  Oncotarget.  8:8226-8238. 2017
2017 RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature.  Oncotarget.  8:38668-38681. 2017
2016 Kinase gene expression profiling of metastatic clear cell renal cell carcinoma tissue identifies potential new therapeutic targets.  PLoS ONE.  11. 2016
2016 RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature 2016
2016 Post-mortem molecular profiling of three psychiatric disorders 2016
2016 aRNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in high performance computing environments 2016
2015 Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.  Science.  347:1436-1441. 2015
2014 DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinoma.  BMC Medicine.  12. 2014

Full Name

  • Brittany Lasseigne