Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation.  Cell Reports.  37. 2021
2021 Lung dendritic cells migrate to the spleen to prime long-lived TCF1hi memory CD8+ T cell precursors after influenza infection.  Science Immunology.  6. 2021
2021 Modulating Th2 Cell Immunity for the Treatment of Asthma.  Frontiers in Immunology.  12. 2021
2019 Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation.  Mammalian Genome.  30:245-259. 2019
2019 Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells.  Science Immunology.  4. 2019
2019 Compartmentalization of dendritic cell and T-cell interactions in the lymph node: Anatomy of T-cell fate decisions.  Immunological Reviews.  289:84-100. 2019
2019 Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants.  Immunity.  50:225-240.e4. 2019
2017 Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection.  Nature Immunology.  18:1249-1260. 2017
2017 CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs.  Immunity.  47:251-267.e7. 2017
2017 T Cells in Allergic Asthma: Key Players Beyond the Th2 Pathway.  Current Allergy and Asthma Reports.  17. 2017
2016 T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite.  Immunity.  44:259-273. 2016
2014 Dendritic cells and B cells: Unexpected partners in Th2 development.  Journal of Immunology.  193:1531-1537. 2014
2014 Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T Cells.  Immunity.  41:127-140. 2014
2014 FoxP3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability.  Nature Communications.  5. 2014
2014 Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells.  Journal of Experimental Medicine.  211:1637-1655. 2014
2013 CD4+ T helper cells use CD154-CD40 interactions to counteract T reg cell- mediated suppression of CD8+ T cell responses to influenza.  Journal of Experimental Medicine.  210:1591-1601. 2013
2013 IL-17-producing B cells combat parasites.  Nature Immunology.  14:419-421. 2013
2012 Regulation of T H2 development by CXCR5 + dendritic cells and lymphotoxin-expressing B cells.  Nature Immunology.  13:681-690. 2012
2012 Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation.  Immunity.  36:847-856. 2012
2012 Unraveling effector functions of B cells during infection: The hidden world beyond antibody production.  Infectious Disorders: Drug Targets.  12:213-221. 2012
2010 Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+T cell responses to influenza.  Nature Immunology.  11:216-224. 2010
2008 Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway.  Journal of Immunology.  181:3524-3534. 2008
2008 Monocyte‐derived dendritic cells in innate and adaptive immunity.  Immunology and Cell Biology.  86:320-324. 2008
2008 Monocyte migration to inflamed skin and lymph nodes is differentially controlled by L-selectin and PSGL-1.  Blood.  111:3126-3130. 2008
2007 Monocyte-Derived Dendritic Cells Formed at the Infection Site Control the Induction of Protective T Helper 1 Responses against Leishmania.  Immunity.  26:519-531. 2007
2005 Monocyte-derived dendritic cells.  Seminars in Immunology.  17:313-318. 2005
2004 Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8- and CD8+ splenic dendritic cells.  Blood.  103:2668-2676. 2004

Education And Training

  • Doctor of Philosophy Level Degree in Microbiology, Autonomous University of Madrid 2007
  • Bachelor's Level Degree in Biology, Complutense University of Madrid 2002

    • Full Name

  • Beatriz Leon-Ruiz