Selected Publications

Academic Article

Year Title Altmetric
2022 Fooling TLR4 to promote fungal virulence.Immunity.  55:1591-1593. 2022
2021 GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammationCell Reports.  37. 2021
2021 Lung dendritic cells migrate to the spleen to prime long-lived TCF1hi memory CD8+ T cell precursors after influenza infectionScience Immunology.  6. 2021
2021 Modulating Th2 Cell Immunity for the Treatment of AsthmaFrontiers in Immunology.  12. 2021
2020 GM-CSF Availability Determines LPS-Mediated Functions in Allergic Inflammation 2020
2019 Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferationMammalian Genome.  30:245-259. 2019
2019 Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cellsScience Immunology.  4. 2019
2019 Compartmentalization of dendritic cell and T-cell interactions in the lymph node: Anatomy of T-cell fate decisionsImmunological Reviews.  289:84-100. 2019
2019 Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in InfantsImmunity.  50:225-240.e4. 2019
2017 Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infectionNature Immunology.  18:1249-1260. 2017
2017 CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene ProgramsImmunity.  47:251-267.e7. 2017
2017 T Cells in Allergic Asthma: Key Players Beyond the Th2 Pathway.Current Allergy and Asthma Reports.  17:43. 2017
2016 T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust MiteImmunity.  44:259-273. 2016
2014 Dendritic cells and B cells: Unexpected partners in Th2 developmentJournal of Immunology.  193:1531-1537. 2014
2014 Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T CellsImmunity.  41:127-140. 2014
2014 FoxP3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availabilityNature Communications.  5. 2014
2014 Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cellsJournal of Experimental Medicine.  211:1637-1655. 2014
2013 CD4+ T helper cells use CD154-CD40 interactions to counteract T reg cell- mediated suppression of CD8+ T cell responses to influenzaJournal of Experimental Medicine.  210:1591-1601. 2013
2013 IL-17-producing B cells combat parasitesNature Immunology.  14:419-421. 2013
2012 Regulation of T H2 development by CXCR5 + dendritic cells and lymphotoxin-expressing B cellsNature Immunology.  13:681-690. 2012
2012 Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell DifferentiationImmunity.  36:847-856. 2012
2012 Unraveling effector functions of B cells during infection: The hidden world beyond antibody productionInfectious Disorders: Drug Targets.  12:213-221. 2012
2010 Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+T cell responses to influenzaNature Immunology.  11:216-224. 2010
2008 Statins induce regulatory T cell recruitment via a CCL1 dependent pathway.Journal of Immunology.  181:3524-3534. 2008
2008 Monocyte migration to inflamed skin and lymph nodes is differentially controlled by L-selectin and PSGL-1.Blood.  111:3126-3130. 2008
2008 Monocyte-derived dendritic cells in innate and adaptive immunity.Immunology and Cell Biology.  86:320-324. 2008
2007 Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania.Immunity.  26:519-531. 2007
2005 Monocyte-derived dendritic cells.Seminars in Immunology.  17:313-318. 2005
2004 Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8- and CD8+ splenic dendritic cells.Blood.  103:2668-2676. 2004

Education And Training

  • Doctor of Philosophy Level Degree in Microbiology, Autonomous University of Madrid 2007
  • Bachelor's Level Degree in Biology, Complutense University of Madrid 2002
  • Full Name

  • Beatriz Leon-Ruiz