Browse
Browse
Home
People
Organizations
Research
Events
Capability Map
Beatriz Leon-Ruiz Ph.D.
Associate Professor
Close
E-mail
bleon@uab.edu
Visualizations
Co-author Network
Map of Science
Co-investigator Network
Beatriz Leon-Ruiz Ph.D.
Associate Professor
Positions
Scientist (C)
,
UWIRC Microbiome Center
,
School of Medicine
Associate Scientist (C)
,
Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC)
,
School of Medicine
Associate Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
Scientist (C)
,
Center for AIDS Research
,
School of Medicine
Associate Scientist
,
Inflammation, Immunology and Immunotherapeutics
,
O'Neal Comprehensive Cancer Center
Scientist (C)
,
Center for Clinical and Translational Science (CCTS)
,
General Clinical Research Center
Associate Professor (P)
,
Microbiology
,
Academic Joint Departments
Co-Director
,
Microbiology
,
Academic Joint Departments
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
Filter
Year
Title
Altmetric
2021
GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation
.
Cell Reports
. 37.
2021
2021
Lung dendritic cells migrate to the spleen to prime long-lived TCF1hi memory CD8+ T cell precursors after influenza infection
.
Science Immunology
. 6.
2021
2021
Modulating Th2 Cell Immunity for the Treatment of Asthma
.
Frontiers in Immunology
. 12.
2021
2019
Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation
.
Mammalian Genome
. 30:245-259.
2019
2019
Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-T
FH
cells
.
Science Immunology
. 4.
2019
2019
Compartmentalization of dendritic cell and T-cell interactions in the lymph node: Anatomy of T-cell fate decisions
.
Immunological Reviews
. 289:84-100.
2019
2019
Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants
.
Immunity
. 50:225-240.e4.
2019
2017
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection
.
Nature Immunology
. 18:1249-1260.
2017
2017
CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs
.
Immunity
. 47:251-267.e7.
2017
2017
T Cells in Allergic Asthma: Key Players Beyond the Th2 Pathway
.
Current Allergy and Asthma Reports
. 17.
2017
2016
T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite
.
Immunity
. 44:259-273.
2016
2014
Dendritic cells and B cells: Unexpected partners in Th2 development
.
Journal of Immunology
. 193:1531-1537.
2014
2014
Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8
+
T Cells
.
Immunity
. 41:127-140.
2014
2014
FoxP3
+
regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability
.
Nature Communications
. 5.
2014
2014
Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells
.
Journal of Experimental Medicine
. 211:1637-1655.
2014
2013
CD4
+
T helper cells use CD154-CD40 interactions to counteract T reg cell- mediated suppression of CD8
+
T cell responses to influenza
.
Journal of Experimental Medicine
. 210:1591-1601.
2013
2013
IL-17-producing B cells combat parasites
.
Nature Immunology
. 14:419-421.
2013
2012
Regulation of T
H
2 development by CXCR5
+
dendritic cells and lymphotoxin-expressing B cells
.
Nature Immunology
. 13:681-690.
2012
2012
Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
.
Immunity
. 36:847-856.
2012
2012
Unraveling effector functions of B cells during infection: The hidden world beyond antibody production
.
Infectious Disorders: Drug Targets
. 12:213-221.
2012
2010
Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8
+
T cell responses to influenza
.
Nature Immunology
. 11:216-224.
2010
2008
Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway
.
Journal of Immunology
. 181:3524-3534.
2008
2008
Monocyte‐derived dendritic cells in innate and adaptive immunity
.
Immunology and Cell Biology
. 86:320-324.
2008
2008
Monocyte migration to inflamed skin and lymph nodes is differentially controlled by L-selectin and PSGL-1
.
Blood
. 111:3126-3130.
2008
2007
Monocyte-Derived Dendritic Cells Formed at the Infection Site Control the Induction of Protective T Helper 1 Responses against Leishmania
.
Immunity
. 26:519-531.
2007
2005
Monocyte-derived dendritic cells
.
Seminars in Immunology
. 17:313-318.
2005
2004
Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8- and CD8+ splenic dendritic cells
.
Blood
. 103:2668-2676.
2004
Research
Principal Investigator On
Regulation of T Cell Responses to Allergens and Environmental Microbes
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Regulation of T Cell Responses to Allergens and Environmental Microbes
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Rheumatic Diseases Research Core Centers - P&F 2: Development of New Technology for Autoreactive B Cell Identification and Characterization in Rheumatoid Arthritis
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
Investigator On
B Cells in Health and Disease
awarded by
Emory University
Controlling Th2 Immunity by Tuning CXCL13 Dependent DC Migration in Lymph Nodes
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Impact of SLE-Associated ITGAM Variants on Dendritic Cell Function
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
Molecular Characterization of the Role for T-bet and Bcl-6 in Immune Cell Metabolism and Differentiation
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Rheumatic Diseases Research Core Centers (P30)
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
Teaching
Teaching Activities
GBS742 - Dendritic Cell Biology (Fall Term 2019)
GBS742 - Dendritic Cell Biology (Fall Term 2020)
GBS787 - Special Topics (Fall Term 2018)
Background
Education And Training
Doctor of Philosophy Level Degree in Microbiology,
Autonomous University of Madrid
2007
Bachelor's Level Degree in Biology,
Complutense University of Madrid
2002
Contact
Full Name
Beatriz
Leon-Ruiz