Beatriz Leon-Ruiz Ph.D.

Beatriz Leon-Ruiz Ph.D.
Associate Professor

Scientist (C), UWIRC Microbiome Center , School of Medicine
Associate Scientist (C), Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC) , School of Medicine
Associate Scientist (C), O'Neal Comprehensive Cancer Center , School of Medicine
Scientist (C), Center for AIDS Research , School of Medicine
Associate Scientist, Inflammation, Immunology and Immunotherapeutics , O'Neal Comprehensive Cancer Center
Associate Professor (P), Microbiology , Academic Joint Departments
Co-Director, Microbiology , Academic Joint Departments

Selected Publications

Academic Article

Year	Title	Altmetric
2021	Modulating Th2 Cell Immunity for the Treatment of Asthma. Frontiers in Immunology. 12. 2021
2019	Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation. Mammalian Genome. 30:245-259. 2019
2019	Compartmentalization of dendritic cell and T-cell interactions in the lymph node: Anatomy of T-cell fate decisions. Immunological Reviews. 289:84-100. 2019
2019	Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants. Immunity. 50:225-240.e4. 2019
2017	CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs. Immunity. 47:251-267.e7. 2017
2017	T Cells in Allergic Asthma: Key Players Beyond the Th2 Pathway. Current Allergy and Asthma Reports. 17. 2017
2016	T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite. Immunity. 44:259-273. 2016
2014	Dendritic cells and B cells: Unexpected partners in Th2 development. Journal of Immunology. 193:1531-1537. 2014
2014	Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8⁺ T Cells. Immunity. 41:127-140. 2014
2014	Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells. Journal of Experimental Medicine. 211:1637-1655. 2014
2013	CD4⁺ T helper cells use CD154-CD40 interactions to counteract T reg cell- mediated suppression of CD8⁺ T cell responses to influenza. Journal of Experimental Medicine. 210:1591-1601. 2013
2012	Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation. Immunity. 36:847-856. 2012
2012	Unraveling effector functions of B cells during infection: The hidden world beyond antibody production 2012
2008	Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway. Journal of Immunology. 181:3524-3534. 2008
2008	Monocyte‐derived dendritic cells in innate and adaptive immunity. Immunology and Cell Biology. 86:320-324. 2008
2008	Monocyte migration to inflamed skin and lymph nodes is differentially controlled by L-selectin and PSGL-1. Blood. 111:3126-3130. 2008
2007	Monocyte-Derived Dendritic Cells Formed at the Infection Site Control the Induction of Protective T Helper 1 Responses against Leishmania. Immunity. 26:519-531. 2007
2004	Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8- and CD8+ splenic dendritic cells. Blood. 103:2668-2676. 2004