Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20.  npj Parkinson's Disease.  6. 2020
2020 Trichloroethylene, a ubiquitous environmental contaminant in the risk for Parkinson's disease 2020
2020 LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.  Neurobiology of Disease.  134. 2020
2019 Sex Differences in Rotenone Sensitivity Reflect the Male-to-Female Ratio in Human Parkinson's Disease Incidence.  Toxicological Sciences.  170:133-143. 2019
2019 Response to Rotenone and Parkinson's Disease; Reduced Sensitivity in Females.  Toxicological Sciences.  170:563. 2019
2019 Long-term RNAi knockdown of α-synuclein in the adult rat substantia nigra without neurodegeneration.  Neurobiology of Disease.  125:146-153. 2019
2019 Correction to: Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson’s disease(J Pharmacol Exp Ther. (2013) 345: 1 (125-38) DOI: 10.1124/jpet.112.201558).  Journal of Pharmacology and Experimental Therapeutics.  369:66. 2019
2018 LRRK2 activation in idiopathic Parkinson's disease.  Science Translational Medicine.  10. 2018
2018 Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease.  Neurobiology of Disease.  115:101-114. 2018
2018 Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson's disease.  Neurobiology of Disease.  109:249-257. 2018
2015 The Nurr1 activator 1,1-bis(3′-indolyl)-1-(p-chlorophenyl) methane blocks inflammatory gene expression in BV-2 microglial cells by inhibiting nuclear factor κB.  Molecular Pharmacology.  87:1021-1034. 2015
2015 Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.  Toxicological Sciences.  143:360-373. 2015
2014 Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes.  PLoS ONE.  9. 2014
2013 Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.  Journal of Pharmacology and Experimental Therapeutics.  345:125-138. 2013
2011 Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons.  Journal of Neuroscience Research.  89:406-417. 2011

Chapter

Year Title Altmetric
2017 Etiology and Pathogenesis of Parkinson’s Disease 2017
2016 Toxin-mediated complex I inhibition and parkinson’s disease.  115-137. 2016

Education And Training

  • University of Pittsburgh Neurology, Postdoctoral Fellowship
  • Doctor of Philosophy in Toxicology, Colorado State University 2014
  • Bachelor of Science or Mathematics in Biology / Biological Sciences, Colorado State University 2008

    • Full Name

  • Briana De Miranda