Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Human gut microbial communities dictate efficacy of anti-PD-1 therapy in a humanized microbiome mouse model of glioma. 2021
2020 An individualized mosaic of maternal microbial strains is transmitted to the infant gut microbial communityRoyal Society Open Science.  7. 2020
2019 Reactive astrocytes foster brain metastases via STAT3 signaling.Annals of translational medicine.  7:S83. 2019
2017 Protein kinase CK2 is important for the function of glioblastoma brain tumor initiating cellsJournal of Neuro-Oncology.  132:219-229. 2017
2016 Attenuation of PKR-like ER Kinase (PERK) signaling selectively controls endoplasmic reticulum stress-induced inflammation without compromising immunological responsesJournal of Biological Chemistry.  291:15830-15840. 2016
2016 Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of gliomaOncotarget.  7:20621-20635. 2016
2015 SOCS3 deficiency in myeloid cells promotes tumor development: Involvement of STAT3 activation and myeloid-derived suppressor cellsCancer Immunology Research.  3:727-740. 2015
2015 Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastomaOncotarget.  6:17805-17816. 2015
2014 Involvement of the Janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitisJournal of Interferon and Cytokine Research.  34:577-588. 2014
2014 NF-κB and STAT3 in glioblastoma: Therapeutic targets coming of age 2014
2014 Therapeutic CK2 inhibition attenuates diverse prosurvival signaling cascades and decreases cell viability in human breas cancer cellsOncotarget.  5:6484-6496. 2014
2014 Therapeutic efficacy of suppressing the JAK/STAT pathway in multiple models of experimental autoimmune encephalomyelitisJournal of Immunology.  192:59-72. 2014
2013 Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastomaClinical Cancer Research.  19:6484-6494. 2013
2013 NF-κB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastomaPLoS ONE.  8. 2013
2013 Activation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells 2013
2011 Therapeutic potential of AZD1480 for the treatment of human glioblastomaMolecular Cancer Therapeutics.  10:2384-2393. 2011
2009 Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: Sensitization by radiation and requirement for GRP78 and LRP1Cancer Research.  69:5537-5545. 2009
2008 New molecular targets in angiogenic vessels of glioblastoma tumoursExpert Reviews in Molecular Medicine.  10. 2008
2007 Erratum: HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells (Oncogene (2006) 25, (1721-1732) DOI: 10.1038/sj.onc.1209199)Oncogene.  26:7282. 2007
2006 New concepts regarding focal adhesion kinase promotion of cell migration and proliferationJournal of Cellular Biochemistry.  99:35-52. 2006
2006 HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cellsOncogene.  25:1721-1732. 2006

Chapter

Year Title Altmetric
2015 Protein kinase CK2 and dysregulated oncogenic inflammatory signaling pathways.  259-280. 2015

Education And Training

  • Doctor of Philosophy in Neurobiology and Neurosciences, University of Alabama at Birmingham 2009
  • Bachelor of Science or Mathematics in Biomedical Sciences, University of South Alabama 2004
  • University of Alabama at Birmingham Cell, Developmental and Integrative Biology, Postdoctoral Fellowship 2014
  • Full Name

  • Braden McFarland