Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Effect of body position on intraocular pressure (IOP), intracranial pressure (ICP), and translaminar pressure (TLP) via continuous wireless telemetry in nonhuman primates (NHPs)Investigative Ophthalmology and Visual Science.  61. 2020
2020 In vivo estimation of optic nerve sheath stiffness using noninvasive MRI measurements and finite element modelingJournal of the Mechanical Behavior of Biomedical Materials.  110. 2020
2020 Connective tissue remodeling in myopia and its potential role in increasing risk of glaucoma 2020
2020 Intra-subject variability and diurnal cycle of ocular perfusion pressure as characterized by continuous telemetry in nonhuman primatesInvestigative Ophthalmology and Visual Science.  61. 2020
2020 Association of Long-Duration Spaceflight with Anterior and Posterior Ocular Structure Changes in Astronauts and Their RecoveryJAMA Ophthalmology.  138:553-559. 2020
2020 Acute effects of posture on intraocular pressurePLoS ONE.  15. 2020
2020 Diurnal cycle of translaminar pressure in nonhuman primates quantified with continuous wireless telemetryInvestigative Ophthalmology and Visual Science.  61. 2020
2019 Detection and characterization of tree shrew retinal venous pulsations: An animal model to study human retinal venous pulsationsExperimental Eye Research.  185. 2019
2019 Bacteroides Spp. Blebitis, Keratitis, and Endophthalmitis Following Uncomplicated TrabeculectomyJournal of Glaucoma.  28:e118-e120. 2019
2019 Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III 2019
2019 The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data 2019
2018 The impact of choroidal swelling on optic nerve head deformationInvestigative Ophthalmology and Visual Science.  59:4172-4181. 2018
2018 A novel tree shrew (Tupaia belangeri) model of glaucomaInvestigative Ophthalmology and Visual Science.  59:3136-3143. 2018
2017 The magnitude and time course of IOP change in response to body position change in nonhuman primates measured using continuous IOP telemetryInvestigative Ophthalmology and Visual Science.  58:6232-6240. 2017
2017 The impact of ocular hemodynamics and intracranial pressure on intraocular pressure during acute gravitational changes 2017
2017 Deformation of the lamina cribrosa and optic nerve due to changes in cerebrospinal fluid pressureInvestigative Ophthalmology and Visual Science.  58:2070-2078. 2017
2017 Characterization of the mechanical behavior of the optic nerve sheath and its role in spaceflight-induced ophthalmic changesBiomechanics and Modeling in Mechanobiology.  16:33-43. 2017
2017 Reply 2017
2016 Prevalence of Subretinal Drusenoid Deposits in Older Persons with and without Age-Related Macular Degeneration, by Multimodal Imaging 2016
2016 Finite element modeling of factors influencing optic nerve head deformation due to intracranial pressureInvestigative Ophthalmology and Visual Science.  57:1901-1911. 2016
2016 System for rapid, precise modulation of intraocular pressure, toward minimally-invasive in vivo measurement of intracranial pressurePLoS ONE.  11. 2016
2014 Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and developmentPLoS ONE.  9. 2014
2013 A minimally invasive implantable wireless pressure sensor for continuous IOP monitoringIEEE Transactions on Biomedical Engineering.  60:250-256. 2013
2012 Orexin 1 receptors are a novel target to modulate panic responses and the panic brain networkPhysiology and Behavior.  107:733-742. 2012
2012 Dorsomedial/perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradientInvestigative Ophthalmology and Visual Science.  53:7328-7335. 2012
2012 Activation of the orexin 1 receptor is a critical component of CO 2-mediated anxiety and hypertension but not bradycardiaNeuropsychopharmacology.  37:1911-1922. 2012
2011 Clinical profiles of primary open angle glaucoma versus normal tension glaucoma patients: A pilot studyCurrent Eye Research.  36:429-435. 2011
2011 Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complexChannels.  5. 2011
2011 Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex.Channels.  5:449-456. 2011
2004 Dorsomedial hypothalamic sites where disinhibition evokes tachycardia correlate with location of raphe-projecting neurons 2004
2003 Microinjection of muscimol into raphe pallidus suppresses tachycardia associated with air stress in conscious rats 2003
2003 Microinjection of muscimol into raphe pallidus suppresses tachycardia associated with air stress in conscious rats. 2003
2002 Microinjection of muscimol into Raphe Pallidus suppresses stress-induced tachycardiaThe FASEB Journal.  16:A503-A503. 2002
2002 Neurons in the dorsal hypothalamic area (DA) that project to the raphe pallidus (RP) are activated by experimental stress.The FASEB Journal.  16:A503-A504. 2002
2002 The dorsomedial hypothalamus and the response to stress: Part renaissance, part revolution 2002
2002 Tachycardia evoked by disinhibition of the dorsomedial hypothalamus in rats is mediated through medullary raphe 2002
2002 Tachycardia evoked by disinhibition of the dorsomedial hypothalamus in rats is mediated through medullary raphe 2002

Education And Training

  • Doctor of Medicine, Indiana University-Purdue University Indianapolis 2004
  • Doctor of Philosophy in Medical Neurobiology, Indiana University System : Indiana University/Purdue University at Indianapolis 2004
  • Bachelor of Arts in Biology, Wabash College 1997
  • Indiana University SOM, Internship 2005
  • UAB Hospital, Residency 2008
  • Duke Eye Center (DUMC), Postdoctoral Fellowship 2010
  • Duke Eye Center (DUMC), Postdoctoral Fellowship 2009
  • Full Name

  • Brian Samuels