• Brian Casey is originally from Pennsylvania, and earned his Doctor of Medicine degree at Temple University in Philadelphia. He then did his OB/GYN residency training at Saint Barnabas Medical Center in New Jersey and subsequently completed his Maternal-Fetal Medicine training at the University of Texas Southwestern Medical Center.

    Dr. Casey spent 23 years on faculty at Parkland Hospital/UT Southwestern before coming to University of Alabama at Birmingham as Division Director of Maternal Fetal Medicine. He has been a productive clinician-researcher including serving as the Principal Investigator for the Eunice Kennedy-Shriver NICHD Maternal-Fetal Medicine Units Network TSH Trial. This landmark investigation of subclinical hypothyroidism involved screening more than 97,000 pregnant women nationally and a 92% five-year developmental follow-up of their offspring. Dr. Casey recently received the Roy M. Pitkin Award from the American Congress of Obstetricians and Gynecologists for a randomized controlled trial in gestational diabetes and the Norman F. Gant Award for Best Research in Maternal-Fetal Medicine for his work on the TSH Trial.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2020 Effect of Thyroxine Therapy on Depressive Symptoms Among Women With Subclinical Hypothyroidism 2020
    2020 Effect of Treatment of Mild Gestational Diabetes on Long-Term Maternal Outcomes 2020
    2020 Health resource utilization of labor induction versus expectant management 2020
    2020 Hepatitis C Virus Antibody Screening in a Cohort of Pregnant Women: Identifying Seroprevalence and Risk Factors 2020
    2020 Association between Features of Spontaneous Late Preterm Labor and Late Preterm Birth 2020
    2020 Maternal Sense of Control During Childbirth and Infant Feeding Method 2020
    2020 The relationship of maternal glycemia to childhood obesity and metabolic dysfunction 2020
    2019 Closed Incision Negative Pressure Therapy in Morbidly Obese Women Undergoing Cesarean Delivery: A Randomized Controlled Trial 2019
    2019 Thyroid Function Test Abnormalities during Pregnancy 2019
    2019 Elective Induction of Labor in the 39th Week of Gestation Compared With Expectant Management of Low-Risk Multiparous Women 2019
    2019 Association of Gestational Diabetes Mellitus with Neonatal Respiratory Morbidity 2019
    2019 Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery: A Secondary Analysis of a Randomized Clinical Trial 2019
    2018 Child Neurodevelopmental Outcomes by Prepregnancy Body Mass Index and Gestational Weight Gain 2018
    2018 Thyroid function in neonates of women with subclinical hypothyroidism or hypothyroxinemia 2018
    2018 Labor induction versus expectant management in low-risk nulliparous women 2018
    2018 The FL/AC Ratio for Prediction of Shoulder Dystocia in Women with Gestational Diabetes 2018
    2018 Pregnancy-associated hypertension and offspring cardiometabolic health 2018
    2017 Predictive Characteristics of Elevated 1-Hour Glucose Challenge Test Results for Gestational Diabetes 2017
    2017 The FL/AC ratio for prediction of shoulder dystocia in women with gestational diabetes 2017
    2017 Impact of metabolic acidemia at birth on neonatal outcomes in infants born before 34 weeks’ gestation 2017
    2017 Subclinical hypothyroidism or hypothyroxinemia in pregnancy 2017
    2017 Treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancy 2017
    2017 Treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancy 2017
    2017 Infant outcomes among women with Zika virus infection during pregnancy: results of a large prenatal Zika screening program 2017
    2017 Pregnancies after the diagnosis of mild gestational diabetes mellitus and risk of cardiometabolic disorders 2017
    2016 Relationship between Excessive Gestational Weight Gain and Neonatal Adiposity in Women with Mild Gestational Diabetes Mellitus 2016
    2016 Antenatal betamethasone for women at risk for late preterm delivery 2016
    2016 Antenatal betamethasone for women at risk for late preterm delivery 2016
    2016 Carpenter-coustan compared with national diabetes data group criteria for diagnosing gestational diabetes 2016
    2016 Pregnancy-associated hypertension in glucose-intolerant pregnancy and subsequent metabolic syndrome 2016
    2015 Association of influenza vaccination on decreased stillbirth rate 2015
    2015 Mild gestational diabetes mellitus and long-term child health 2015
    2015 Asian women have attenuated sympathetic activation but enhanced renal-adrenal responses during pregnancy compared to Caucasian women 2015
    2015 Does maternal body mass index influence treatment effect in women with mild gestational diabetes? 2015
    2015 Glyburide in Women with Mild Gestational Diabetes: A Randomized Controlled Trial 2015
    2015 Metabolic Acidemia in Live Births at 35 Weeks of Gestation or Greater 2015
    2015 Reply 2015
    2014 Thyroid screening in pregnancy 2014
    2014 Inadequate weight gain in overweight and obese pregnant women: What is the effect on fetal growth? 2014
    2014 Is total thyroxine better than free thyroxine during pregnancy? 2014
    2014 Subsequent pregnancy outcomes in women previously diagnosed with subclinical hypothyroidism 2014
    2014 The debate on thyroid screening during pregnancy continues 2014
    2013 Customized versus population approach for evaluation of fetal overgrowth 2013
    2013 The obstetric and neonatal implications of a low value on the 50-g glucose screening test 2013
    2012 Perinatal outcomes in hispanic and non-hispanic white women with mild gestational diabetes 2012
    2012 Sympathetic activation during early pregnancy in humans 2012
    2012 Relationship of subclinical thyroid disease to the incidence of gestational diabetes 2012
    2012 An immunologic basis for placental insufficiency in fetal growth restriction 2012
    2012 Fetal male gender and the benefits of treatment of mild gestational diabetes mellitus 2012
    2012 Maternal BMI, glucose tolerance, and adverse pregnancy outcomes 2012
    2012 Subclinical thyroid disease and the incidence of hypertension in pregnancy 2012
    2011 Subclinical thyroid dysfunction during pregnancy 2011
    2011 Thyroid disease in pregnancy 2011
    2011 Glycemic characteristics and neonatal outcomes of women treated for mild gestational diabetes 2011
    2011 Antithyroid antibodies and parity: Further evidence for microchimerism in autoimmune thyroid disease 2011
    2011 In reply 2011
    2011 The relationship between maternal glycemia and perinatal outcome 2011
    2010 Pregnancy outcomes after orthopedic trauma 2010
    2010 A multicenter, randomized trial of treatment for mild gestational diabetes 2010
    2010 Diagnostic dilemmas in a pregnant woman with influenza a (H1N1) infection 2010
    2010 Prediction of diabetes recurrence in women with class A(Diet-Treated) gestational diabetes 2010
    2010 Pregnancy outcomes in women with thyroid peroxidase antibodies 2010
    2009 In reply 2009
    2009 A multicenter, randomized trial of treatment for mild gestational diabetes 2009
    2009 Weekly compared with daily blood glucose monitoring in women with diet-treated gestational diabetes 2009
    2008 Diet-treated gestational diabetes mellitus: comparison of early vs routine diagnosis 2008
    2008 Predicting macrosomia 2008
    2007 Labor and Delivery Management for Women With Diabetes 2007
    2007 Perinatal significance of isolated maternal hypothyroxinemia identified in the first half of pregnancy 2007
    2006 Long-term fetal outcomes in pregnant trauma patients 2006
    2006 Placental transfer of rosiglitazone in the ex vivo human perfusion model 2006
    2006 Reply 2006
    2006 Thyroid disease in pregnancy 2006
    2006 Subclinical hypothyroidism and pregnancy 2006
    2006 A randomized trial of coached versus uncoached maternal pushing during the second stage of labor 2006
    2006 In reply [4] 2006
    2006 Subclinical hyperthyroidism and pregnancy outcomes 2006
    2005 Environmental contaminants and maternal thyroid function 2005
    2005 Subclinical hypothyroidism and pregnancy outcomes [5] (multiple letters) 2005
    2005 Human myometrial gene expression before and during parturition 2005
    2005 Subclinical hypothyroidism and pregnancy outcomes 2005
    2005 A randomized trial of the effects of coached vs uncoached maternal pushing during the second stage of labor on postpartum pelvic floor structure and function 2005
    2005 Obstetric antecedents for postpartum pelvic floor dysfunction 2005
    2005 Thyroid-stimulating hormone in singleton and twin pregnancy: Importance of gestational age-specific reference ranges 2005
    2003 Maternal diabetes mellitus and infant malformations [3] (multiple letters) 2003
    2002 Maternal diabetes mellitus and infant malformations 2002
    2001 The continuing value of the Apgar score for the assessment of newborn infants 2001
    2001 Lack of utility of amniotic fluid index in predicting perinatal morbidity and mortality [4] (multiple letters) 2001
    2001 Outcomes among term infants when two-hour postnatal pH is compared with pH at delivery 2001
    2000 Ex vivo human placental transfer of trovafloxacin 2000
    2000 Predictive value of serial middle cerebral and renal artery pulsatility indices in fetuses with oligohydramnios 2000
    2000 Pregnancy outcomes after antepartum diagnosis of oligohydramnios at or beyond 34 weeks' gestation 2000
    1999 Birth weight in relation to morbidity and mortality among newborn infants 1999
    1998 Placental transfer of ritonavir with zidovudine in the ex vivo placental perfusion model 1998
    1998 Pregnancy outcomes in women with gestational diabetes compared with the general obstetric population: In reply 1998
    1997 Pregnancy outcomes in women with gestational diabetes compared with the general obstetric population 1997
    1997 Intraventricular Hemorrhage and Fetal Heart Rate in Very Low Birth Weight Infants 1997
    1997 Chorioamnionitis and endometritis 1997
    1996 Cholecystitis in Pregnancy 1996


    Year Title Altmetric
    2012 Hypothyroidism and Hyperthyroidism.  178-182. 2012
    2010 Hyperthyroidism and Hypothyroidism in Pregnancy.  237-242. 2010
    2010 Thyroid Disease in Pregnancy.  322-334. 2010
    2008 Maternal Hypothyroidism and Hyperthyroidism.  186-191. 2008

    Research Overview

  • -Endocrinopathies of pregnancy, including diabetes and thyroid disease
    -Labor management
    -Medical and obstetrical complications of pregnancy
  • Principal Investigator On

  • Private Grant  awarded by MELLITUS, LLC 2018
  • Education And Training

  • Doctor of Medicine, Temple University 1991
  • Saint Barnabas Medical Center, Residency 1995
  • Parkland Health and Hospital System, Postdoctoral Fellowship 1997
  • Full Name

  • Brian Casey