Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Successful Treatment of a Critically Ill COVID-19 Patient Using Continuous Renal Replacement Therapy With Enhanced Cytokine Removal and Tocilizumab: A Case ReportFrontiers in Medicine.  8. 2021
2021 End-of-Procedure Volume Responsiveness Defined by the Passive Leg Raise Test Is Not Associated With Acute Kidney Injury After Cardiopulmonary Bypass 2021
2021 CRRT prescription and delivery of dose.Seminars in Dialysis2021
2021 Urinary exosomes identify inflammatory pathways in vancomycin associated acute kidney injuryInternational Journal of Molecular Sciences.  22:1-14. 2021
2021 Impact of crrt in patients with pards treated with vv-ecmo 2021
2021 Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19Intensive Care Medicine.  47:208-221. 2021
2021 AKI treated with renal replacement therapy in critically ill patients with COVID-19Journal of the American Society of Nephrology.  32:161-176. 2021
2021 Anticoagulation strategies in continuous renal replacement therapySeminars in Dialysis2021
2021 Incidence and predictors of early and delayed renal function decline after aortic aneurysm repair in the Vascular Quality Initiative databaseJournal of Vascular Surgery2021
2021 Understanding the andromeda strain – The role of cytokine release, coagulopathy and antithrombin III in SARS-CoV2 critical illnessBlood Reviews.  45. 2021
2020 COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) WorkgroupNature Reviews Nephrology.  16:747-764. 2020
2020 Precision renal replacement therapyCurrent Opinion in Critical Care.  26:574-580. 2020
2020 Publisher Correction: COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup (Nature Reviews Nephrology, (2020), 10.1038/s41581-020-00356-5)Nature Reviews Nephrology.  16:765. 2020
2020 Revisiting filtration fraction as an index of the risk of hemofilter clotting in continuous venovenous hemofiltrationClinical Journal of the American Society of Nephrology.  15:1660-1662. 2020
2020 The bio-sonographic index. A novel modality for early detection of acute kidney injury after complex vascular surgery. A protocol for an exploratory prospective studyPLoS ONE.  15. 2020
2020 Preparedness of Kidney Replacement Therapy in the Critically Ill During COVID-19 SurgeKidney International Reports.  5:961-964. 2020
2020 Potassium disorders in pediatric emergency department: Clinical spectrum and managementArchives de Pédiatrie.  27:146-151. 2020
2019 Hyperammonemia, the Last Indication of High-Volume Hemodiafiltration in Adult and Children: A Structured ReviewBlood Purification.  48:330-335. 2019
2019 Quality of care and safety measures of acute renal replacement therapy: Workgroup statements from the 22nd acute disease quality initiative (ADQI) consensus conferenceJournal of Critical Care.  54:52-57. 2019
2019 Quality improvement goals for acute kidney injuryClinical Journal of the American Society of Nephrology.  14:941-953. 2019
2019 Web Exclusive. Annals On Call - Care of Patients With Acute Kidney InjuryAnnals of Internal Medicine.  170:OC1. 2019
2019 Timing of Renal Replacement Therapy for Acute Kidney InjuryJournal of Intensive Care Medicine.  34:94-103. 2019
2018 A Monte Carlo Simulation Approach for Beta-Lactam Dosing in Critically Ill Patients Receiving Prolonged Intermittent Renal Replacement TherapyJournal of Clinical Pharmacology.  58:1254-1265. 2018
2018 Challenges of performing renal replacement therapy in the intensive care unit: The nephrologist perspectiveClinical Nephrology.  90:11-17. 2018
2018 Renal replacement therapy intensity for acute kidney injury and recovery to dialysis independence: A systematic review and individual patient data meta-analysisNephrology Dialysis Transplantation.  33:1017-1024. 2018
2017 Managing issues in dialysis for the patient with AKIClinical Journal of the American Society of Nephrology.  12:1538-1542. 2017
2017 Renal Support for Acute Kidney Injury in the Developing WorldKidney International Reports.  2:559-578. 2017
2017 Current state of the art for renal replacement therapy in critically ill patients with acute kidney injuryIntensive Care Medicine.  43:841-854. 2017
2016 Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: Practical applications 2016
2016 Nomenclature for renal replacement therapy in acute kidney injury: Basic principles 2016
2016 Precision Continuous Renal Replacement Therapy and Solute ControlBlood Purification.  42:238-247. 2016
2016 We Use Heparin as the Anticoagulant for CRRTSeminars in Dialysis.  29:272-274. 2016
2016 Pharmacokinetics and pharmacodynamics of extended infusion versus short infusion piperacillin-tazobactam in critically Ill patients undergoing CRRTClinical Journal of the American Society of Nephrology.  11:1377-1383. 2016
2015 Assessing continuous renal replacement therapy as a rescue strategy in cardiorenal syndrome 1Clinical Kidney Journal.  8:87-92. 2015
2015 A prospective international multicenter study of AKI in the intensive care unitClinical Journal of the American Society of Nephrology.  10:1324-1331. 2015
2015 A multi-center, randomized, controlled, pivotal study to assess the safety and efficacy of a selective cytopheretic device in patients with acute kidney injuryPLoS ONE.  10. 2015
2015 Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: A multicenter prospective observational studyPLoS ONE.  10. 2015
2014 A continuous veno-venous hemofiltration protocol with anticoagulant citrate dextrose formula A and a calcium-containing replacement fluid 2014
2014 A patient with AKI after cardiac surgeryClinical Journal of the American Society of Nephrology.  9:1470-1478. 2014
2014 Efficacy and safety of 5 anesthetics in adult zebrafish (Danio rerio) 2014
2013 Association between renal replacement therapy in critically ill patients with severe acute kidney injury and mortalityJournal of Critical Care.  28:1011-1018. 2013
2013 The effect of the selective Cytopheretic device on acute kidney injury outcomes in the intensive care unit: A multicenter pilot studySeminars in Dialysis.  26:616-623. 2013
2013 Continuous renal-replacement therapy for acute kidney injury.New England Journal of Medicine.  368:1160-1161. 2013
2013 Continuous renal replacement therapy (CRRT)Studies in Computational Intelligence.  405:929-1009. 2013
2012 Continuous renal-replacement therapy for acute kidney injuryNew England Journal of Medicine.  367:2505-2514. 2012
2012 Advances in continuous renal replacement therapy: Citrate anticoagulation updateBlood Purification.  34:88-93. 2012
2012 Critical care nephrology: Management of acid-base disorders with CRRTKidney International.  82:9-18. 2012
2012 Solute clearance in CRRT: Prescribed dose versus actual delivered doseNephrology Dialysis Transplantation.  27:952-956. 2012
2012 Pharmacokinetics and Pharmacodynamics of Piperacillin-Tazobactam in 42 patients treated with Concomitant CRRTClinical Journal of the American Society of Nephrology.  7:452-457. 2012
2012 Hepatorenal syndrome: The 8 th international consensus conference of the Acute Dialysis Quality Initiative (ADQI) Group 2012
2011 Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequencesBMC Nephrology.  12. 2011
2011 Management of complications in renal replacement therapySeminars in Dialysis.  24:164-168. 2011
2011 Renal replacement therapy in special settings: Extracorporeal support devices in liver failureSeminars in Dialysis.  24:197-202. 2011
2010 Development, implementation, and results of the ASN in-training examination for fellowsClinical Journal of the American Society of Nephrology.  5:328-334. 2010
2009 Citrate anticoagulation for continuous renal replacement therapy (CRRT) in patients with acute kidney injury admitted to the intensive care unitNDT Plus.  2:439-447. 2009
2009 A comparison of observed versus estimated baseline creatinine for determination of RIFLE class in patients with acute kidney injuryNephrology Dialysis Transplantation.  24:2739-2744. 2009
2009 Outcomes of critically ill children requiring continuous renal replacement therapyJournal of Critical Care.  24:394-400. 2009
2009 Anticoagulation for continuous renal replacement therapySeminars in Dialysis.  22:141-145. 2009
2009 The clinical application of CRRT - Current statusSeminars in Dialysis.  22:107. 2009
2009 Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injuryJournal of Critical Care.  24:129-140. 2009
2009 Discontinuation of continuous renal replacement therapy: A post hoc analysis of a prospective multicenter observational studyCritical Care Medicine.  37:2576-2582. 2009
2008 The epidemiology of severe acute kidney injury: From BEST to PICARD, in acute kidney injury: New concepts 2008
2008 Standard versus high-dose CVVHDF for ICU-related acute renal failureJournal of the American Society of Nephrology.  19:1233-1238. 2008
2008 Delivery of renal replacement therapy in acute kidney injury: What are the key issues?Clinical Journal of the American Society of Nephrology.  3:869-875. 2008
2008 Efficacy and safety of renal tubule cell therapy for acute renal failureJournal of the American Society of Nephrology.  19:1034-1040. 2008
2008 Treatment of patients with cardiac surgery associated-acute kidney injury 2008
2007 Continuous renal replacement therapy: A worldwide practice survey: The Beginning and Ending Supportive Therapy for the Kidney (B.E.S.T. Kidney) InvestigatorsIntensive Care Medicine.  33:1563-1570. 2007
2007 Sustained low-efficiency dialysisContributions to Nephrology.  156:320-324. 2007
2007 Septic acute kidney injury in critically ill patients: Clinical characteristics and outcomesClinical Journal of the American Society of Nephrology.  2:431-439. 2007
2007 Patient and kidney survival by dialysis modality in critically ill patients with acute kidney injury 2007
2006 A practical citrate anticoagulation continuous venovenous hemodiafiltration protocol for metabolic control and high solute clearance.Clinical Journal of the American Society of Nephrology.  1:79-87. 2006
2005 Acute renal failure in critically ill patients: A multinational, multicenter study 2005
2005 External validation of severity scoring systems for acute renal failure using a multinational databaseCritical Care Medicine.  33:1961-1967. 2005
2005 Renal replacement therapy III: IHD, CRRT, SLEDCritical Care Clinics.  21:367-378. 2005
2004 Vascular grafts for hemodialysis: Types, sites and techniquesContributions to Nephrology.  142:73-93. 2004
2004 Diuretics and mortality in acute renal failureCritical Care Medicine.  32:1669-1677. 2004
2002 Normal radiographs in patients with persistent "hip pain" - Value of magnetic resonance imagingJournal of Rheumatology.  29:2463-2465. 2002
2001 Simplified citrate anticoagulation for continuous renal replacement therapyKidney International.  60:370-374. 2001
2000 Dilative cardiomyopathy leading to congestive heart failure in a male squirrel monkey (Saimiri sciureus)Journal of Medical Primatology.  29:42-45. 2000
1999 Predictors of adequacy of arteriovenous fistulas in hemodialysis patientsKidney International.  56:275-280. 1999

Chapter

Year Title Altmetric
2021 RRT: Anticoagulation 2021
2017 Anticoagulation for Continuous Renal Replacement Therapy.  380-385.e1. 2017
2016 Complications of continuous renal replacement therapy (CRRT).  211-219. 2016
2015 Clinical pearls: Renal replacement therapy for acute kidney injury in the postoperative period.  37-51. 2015
2014 Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences.  1-28. 2014
2013 Acute kidney injury: Definitions and general approach.  165-173. 2013
2013 Specific etiologies.  199-236. 2013
2013 Continuous Renal Replacement Therapy (CRRT)..  929-1009. 2013

Research Overview

  • Acute Kidney Injury
  • Principal Investigator On

  • International Drug Induced Renal Injury Consortium (Direct)  awarded by INTERNATIONAL SAE CONSORTIOUM, LTD
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by CYTOPHERX, INC.
  • Private Grant  awarded by CYTOPHERX, INC.
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by GAMBRO HEALTHCARE
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by AM-PHARMA BV
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by NXSTAGE MEDICAL, INC.
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by FRESENIUS MEDICAL CARE
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Private Grant  awarded by ASTUTE MEDICAL, INC.
  • Private Grant  awarded by Baxter Healthcare Corporation
  • Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI): A Multi-Centre, Randomized, Controlled Trial  awarded by ST. MICHAEL'S HOSPITAL
  • Strategy for Timely Intervention of Renal Support (STIRS)  awarded by University of California, San Diego
  • Timely Intervention for Renal Support: A Feasibility Study  awarded by University of California, San Diego
  • Teaching Activities

  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2020) 2020
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2020) 2020
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2020) 2020
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2020) 2020
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2019) 2019
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018 - 2019
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2018) 2018
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2017) 2017
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2017) 2017
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2017) 2017
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2017) 2017
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2017) 2017
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2016) 2016
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2015) 2015
  • 29-100 - NEPHROLOGY CONSULT (Fall Term 2015) 2015
  • 29-100 - NEPHROLOGY CONSULT (Spring Term 2015) 2015
  • 28-460 - CLINICAL NEPHROLOGY CONSULT SERVICE (Fall Term 2008) 2008 - 2009
  • 28-460 - CLINICAL NEPHROLOGY CONSULT SERVICE (Fall Term 2008) 2008
  • 28-460 - CLINICAL NEPHROLOGY CONSULT SERVICE (Spring Term 2008) 2008
  • 28-460 - CLINICAL NEPHROLOGY CONSULT SERVICE (Spring Term 2008) 2008
  • 28-460 - CLINICAL NEPHROLOGY CONSULT SERVICE (Fall Term 2007) 2007
  • Education And Training

  • UAB Hospital, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Doctor of Medicine in Internal Medicine Residency Program, University of Alabama at Birmingham 1994
  • Full Name

  • Ashita Tolwani