Selected Publications

Academic Article

Year Title Altmetric
2022 Neuroendocrine signaling in the skin with a special focus on the epidermal neuropeptides 2022
2022 Editorial: Role of pigmentation in melanomaFrontiers in Oncology.  12. 2022
2022 Novel CYP11A1-Derived Vitamin D and Lumisterol Biometabolites for the Management of COVID-19Nutrients.  14. 2022
2022 An Appraisal to Address Health Consequences of Vitamin D Deficiency With Food Fortification and Supplements: Time to Act! 2022
2022 Serotonin, melatonin and their precursors and metabolites and vitamin D3 derivatives in honey 2022
2022 CYP11A1-derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomasInternational Journal of Oncology.  61. 2022
2022 Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPARγ receptors 2022
2022 Vitamin D Signaling in Psoriasis: Pathogenesis and TherapyInternational Journal of Molecular Sciences.  23. 2022
2022 Molecular and structural basis of interactions of vitamin D3 hydroxyderivatives with aryl hydrocarbon receptor (AhR): An integrated experimental and computational studyInternational Journal of Biological Macromolecules.  209:1111-1123. 2022
2022 Disturbed expression of vitamin D and retinoic acid-related orphan receptors α and γ and of megalin in inflammatory skin diseasesExperimental Dermatology.  31:781-788. 2022
2022 Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3Bioorganic Chemistry.  121. 2022
2022 Revisiting the role of melatonin in human melanocyte physiology: A skin context perspectiveJournal of Pineal Research.  72. 2022
2022 Current Insights Into the Role of Neuropeptide Y in Skin Physiology and PathologyFrontiers in Endocrinology.  13. 2022
2022 Melanoma, Melanin, and Melanogenesis: The Yin and Yang RelationshipFrontiers in Oncology.  12. 2022
2022 Assessment of Melatonin-Cultured Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials for Wound HealingAntioxidants.  11. 2022
2022 Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infectionCellular and Molecular Life Sciences.  79. 2022
2022 Protective Role of Melatonin and Its Metabolites in Skin AgingInternational Journal of Molecular Sciences.  23. 2022
2022 The Challenge of Melanoma ChemopreventionCancer Prevention Research.  15:71-74. 2022
2022 Modulation by 17,20s(Oh)2pd of fibrosis-related mediators in dermal fibroblast lines from healthy donors and from patients with systemic sclerosisInternational Journal of Molecular Sciences.  23. 2022
2022 The Brain–Skin Axis in Psoriasis—Psychological, Psychiatric, Hormonal, and Dermatological AspectsInternational Journal of Molecular Sciences.  23. 2022
2022 Vitamin D3 and its hydroxyderivatives as promising drugs against COVID-19: a computational studyJournal of Biomolecular Structure and Dynamics.  40:11594-11610. 2022
2021 Editorial: Steroids and Secosteroids in the Modulation of Inflammation and ImmunityFrontiers in Immunology.  12. 2021
2021 1,25-dihydroxyvitamin d3 and 20-hydroxyvitamin d3 upregulate lair-1 and attenuate collagen induced arthritisInternational Journal of Molecular Sciences.  22. 2021
2021 Evidence for Involvement of Nonclassical Pathways in the Protection From UV-Induced DNA Damage by Vitamin D–Related CompoundsJBMR Plus.  5. 2021
2021 Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs)Scientific Reports.  11. 2021
2021 Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patientsOncogene.  40:6329-6342. 2021
2021 Correction: Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients (Oncogene, (2021), 40, 45, (6329-6342), 10.1038/s41388-021-01998-w)Oncogene.  40:6394. 2021
2021 The Role of the Vitamin D Receptor in the Pathogenesis, Prognosis, and Treatment of Cutaneous MelanomaFrontiers in Oncology.  11. 2021
2021 Dietary table grape protects against ultraviolet photodamage in humans: 2. molecular biomarker studiesJournal of the American Academy of Dermatology.  85:1032-1034. 2021
2021 Expression of antimicrobial peptide genes oscillates along day/night rhythm protecting mice skin from bacteriaExperimental Dermatology.  30:1418-1427. 2021
2021 Selective ability of rat 7-Dehydrocholesterol reductase (DHCR7) to act on some 7-Dehydrocholesterol metabolites but not on lumisterol metabolites 2021
2021 Simultaneous measurement of 13 circulating vitamin D3 and D2 mono and dihydroxy metabolites using liquid chromatography mass spectrometryClinical Chemistry and Laboratory Medicine.  59:1642-1652. 2021
2021 Detection of Serotonin, Melatonin, and Their Metabolites in Honey 2021
2021 Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agentsEuropean Journal of Medicinal Chemistry.  220. 2021
2021 17,20s(Oh)2pd can prevent the development of skin fibrosis in the bleomycin-induced scleroderma mouse modelInternational Journal of Molecular Sciences.  22. 2021
2021 The impact of vitamin d on skin agingInternational Journal of Molecular Sciences.  22. 2021
2021 Vitamin D and lumisterol novel metabolites can inhibit SARS-CoV-2 replication machinery enzymes 2021
2021 Knocking out the vitamin d receptor enhances malignancy and decreases responsiveness to vitamin d3 hydroxyderivatives in human melanoma cellsCancers.  13. 2021
2021 20S-Hydroxyvitamin D3, a Secosteroid Produced in Humans, Is Anti-Inflammatory and Inhibits Murine Autoimmune ArthritisFrontiers in Immunology.  12. 2021
2021 The significance of CYP11A1 expression in skin physiology and pathologyMolecular and Cellular Endocrinology.  530. 2021
2021 Evaluation of polymeric matrix loaded with melatonin for wound dressingInternational Journal of Molecular Sciences.  22. 2021
2021 Immunological aspects of skin aging in atopic dermatitisInternational Journal of Molecular Sciences.  22. 2021
2021 Pigmentation levels affect melanoma responses to Coriolus versicolor extract and play a crucial role in melanoma-mononuclear cell crosstalkInternational Journal of Molecular Sciences.  22. 2021
2021 5′-Cap‒Dependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell CarcinomaJournal of Investigative Dermatology.  141:742-753.e10. 2021
2021 Differential and overlapping effects of melatonin and its metabolites on keratinocyte function: Bioinformatics and metabolic analysesAntioxidants.  10. 2021
2021 Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cellsJournal of Pineal Research.  70. 2021
2021 UVBstimulatesproductionofenkephalinsandother neuropeptides by skin-resident cells 2021
2021 Nme1 and Nme2 genes exert metastasis-suppressor activities in a genetically engineered mouse model of UV-induced melanomaBritish Journal of Cancer.  124:161-165. 2021
2021 Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ 2021
2021 New effects of caffeine on corticotropin-releasing hormone (CRH)-induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the neurogenic non-HPA axis (substance P, p75NTR and TrkA) in ex vivo human male androgenetic scalp hair folliclesBritish Journal of Dermatology.  184:96-110. 2021
2020 Hydroxylumisterols, photoproducts of pre-vitamin d3, protect human keratinocytes against uvb-induced damageInternational Journal of Molecular Sciences.  21:1-18. 2020
2020 Vitamin D and its analogs as anticancer and anti-inflammatory agentsEuropean Journal of Medicinal Chemistry.  207. 2020
2020 Association among vitamin D, retinoic acid-related orphan receptors, and vitamin d hydroxyderivatives in ovarian cancerNutrients.  12:1-23. 2020
2020 COVID-19 and Vitamin D: A lesson from the skinExperimental Dermatology.  29:885-890. 2020
2020 Clinical trials for use of melatonin to fight against COVID-19 are urgently neededNutrients.  12:1-12. 2020
2020 CYP11A1-derived vitamin D3 products protect against UVB-induced inflammation and promote keratinocytes differentiationFree Radical Biology and Medicine.  155:87-98. 2020
2020 Reply to Jakovac and to Rocha et al.: Can vitamin D prevent or manage COVID-19 illness? 2020
2020 Detection of 7-dehydrocholesterol and vitamin D3 derivatives in honeyMolecules.  25. 2020
2020 Photoprotective Properties of Vitamin D and Lumisterol HydroxyderivativesCell Biochemistry and Biophysics.  78:165-180. 2020
2020 Current molecular markers of melanoma and treatment targetsInternational Journal of Molecular Sciences.  21. 2020
2020 Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disordersGenes and Immunity.  21:150-168. 2020
2020 Noncalcemic Vitamin D hydroxyderivatives inhibit human oral squamous cell carcinoma and down-regulate hedgehog and WNT/β-catenin pathways 2020
2020 Editorial: Redox Biology of Skin Aging and Carcinogenesis: the Role of Natural Antioxidants as Potential Protective AgentsFrontiers in Pharmacology.  11. 2020
2020 Essential skin shrinkage: cicatricial ectropion, a histopathologic evaluation and clinical analysis 2020
2020 Characterization of serotonin and N-acetylserotonin systems in the human epidermis and skin cellsJournal of Pineal Research.  68. 2020
2020 (Inverse) agonists of retinoic acid-related orphan receptor γ: Regulation of immune responses, inflammation, and autoimmune diseaseAnnual Review of Pharmacology and Toxicology.  60:371-390. 2020
2020 Coriolus versicolor-derived protein-bound polysaccharides trigger the caspase-independent cell death pathway in amelanotic but not melanotic melanoma cellsPhytotherapy Research.  34:173-183. 2020
2020 Innate Immune Signaling Contributes to Tubular Cell Senescence in the Glis2 Knockout Mouse Model of NephronophthisisAmerican Journal of Pathology.  190:176-189. 2020
2020 Pathogenesis of psoriasis in the "omic" era. Part II Genetic, genomic and epigenetic changes in psoriasis 2020
2020 Pathogenesis of psoriasis in the "omic" era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis 2020
2020 Pathogenesis of psoriasis in the “omic” era. Part IV. Epidemiology, genetics, immunopathogenesis, clinical manifestation and treatment of psoriatic arthritis 2020
2020 Relevance of Vitamin D in melanoma development, progression and therapy 2020
2019 Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levelsScientific Reports.  9. 2019
2019 Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cellsJournal of Pineal Research.  67. 2019
2019 Emerging Roles of GLI-Similar Krüppel-like Zinc Finger Transcription Factors in Leukemia and Other CancersTrends in Cancer.  5:547-557. 2019
2019 On the relationship between VDR, RORα and RORγ receptors expression and HIF1-α levels in human melanomasExperimental Dermatology.  28:1036-1043. 2019
2019 Therapeutic suppression of pulmonary neutrophilia and allergic airway hyperresponsiveness by an RORγt inverse agonistJCI Insight.  4. 2019
2019 Targeting melanocortin receptor type 1 with small peptidesBritish Journal of Dermatology.  181:17-18. 2019
2019 Neuroendocrine aspects of skin agingInternational Journal of Molecular Sciences.  20. 2019
2019 Protective effects of novel derivatives of vitamin D 3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanismsRedox Biology.  24. 2019
2019 Genomic profiling of the steroidogenic acute regulatory protein in breast cancer: In silico assessments and a mechanistic perspectiveCancers.  11. 2019
2019 Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell lineInternational Journal of Oncology.  54:1481-1495. 2019
2019 GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells into Posterior Neural ProgenitorsStem Cells.  37:202-215. 2019
2019 The serum vitamin D metabolome: What we know and what is still to discover 2019
2019 Prominin-1 controls stem cell activation by orchestrating ciliary dynamics 2019
2019 11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γJournal of Lipid Research.  60:1535-1546. 2019
2019 Efficient neural differentiation using single-cell culture of human embryonic stem cellsJournal of Visualized Experiments.  2020. 2019
2019 The nuclear receptor RORα protects against angiotensin ii-induced cardiac hypertrophy and heart failure 2019
2018 Investigation of 20S-hydroxyVitamin D3 analogs and their 1α-OH derivatives as potent Vitamin D receptor agonists with anti-inflammatory activitiesScientific Reports.  8. 2018
2018 Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cellsInternational Journal of Molecular Sciences.  19. 2018
2018 Differential and overlapping effects of 20,23(OH)2 D3 and 1,25(OH)2 D3 on gene expression in human epidermal keratinocytes: Identification of AHR as an alternative receptor for 20,23(OH)2 D3International Journal of Molecular Sciences.  19. 2018
2018 Antiproliferative activity of non-calcemic vitamin D analogs on human melanoma lines in relation to VDR and PDIA3 receptorsInternational Journal of Molecular Sciences.  19. 2018
2018 Melatonin and its derivatives counteract the ultraviolet B radiation-induced damage in human and porcine skin ex vivoJournal of Pineal Research.  65. 2018
2018 Calcitriol and calcidiol can sensitize melanoma cells to low–LET proton beam irradiationInternational Journal of Molecular Sciences.  19. 2018
2018 CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites 2018
2018 Reversing wrinkled skin and hair loss in mice by restoring mitochondrial functionCell Death and Disease.  9. 2018
2018 How UV Light Touches the Brain and Endocrine System Through Skin, and Why 2018
2018 Retinoic acid-related orphan receptor γ (RORγ): Connecting sterol metabolism to regulation of the immune system and autoimmune diseaseCurrent Opinion in Toxicology.  8:66-80. 2018
2018 Transplantable melanomas in hamsters and gerbils as models for human melanoma. Sensitization in melanoma radiotherapy—From animal models to clinical trialsInternational Journal of Molecular Sciences.  19. 2018
2018 Melatonin: A Cutaneous Perspective on its Production, Metabolism, and FunctionsJournal of Investigative Dermatology.  138:490-499. 2018
2018 On the role of classical and novel forms of vitamin D in melanoma progression and management 2018
2018 Properties of purified CYP2R1 in a reconstituted membrane environment and its 25-hydroxylation of 20-hydroxyvitamin D3 2018
2018 Acute hepatologic and nephrologic effects of calcitriol in Syrian golden hamster (Mesocricetus auratus)Acta Biochimica Polonica.  65:351-358. 2018
2018 CKS1 expression in melanocytic nevi and melanomaOncotarget.  9:4173-4187. 2018
2017 1α,20S-Dihydroxyvitamin D Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical SynthesisScientific Reports.  7. 2017
2017 Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterolsScientific Reports.  7. 2017
2017 Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathwaysScientific Reports.  7. 2017
2017 Melatonin, mitochondria, and the skinCellular and Molecular Life Sciences.  74:3913-3925. 2017
2017 Endogenously produced nonclassical vitamin D hydroxy-metabolites act as “biased” agonists on VDR and inverse agonists on RORα and RORγ 2017
2017 Pigmented epithelioid melanocytoma (PEM)/animal type melanoma (ATM): Quest for an origin. report of one unusual case indicating follicular origin and another arising in an intradermal nevusInternational Journal of Molecular Sciences.  18. 2017
2017 Cutaneous Glucocorticoidogenesis and Cortisol Signaling Are Defective in PsoriasisJournal of Investigative Dermatology.  137:1609-1611. 2017
2017 The HGF/SF mouse model of UV-induced melanoma as an in vivo sensor for metastasis-regulating geneInternational Journal of Molecular Sciences.  18. 2017
2017 Does melanin matter in the dark?Experimental Dermatology.  26:595-597. 2017
2017 Inflammatory melanoma in transit metastases with complete response to talimogene laherparepvecJAAD Case Reports.  3:280-283. 2017
2017 Melanin pigmentation and melanomaExperimental Dermatology.  26:555-556. 2017
2017 Metabolism of melatonin in the skin: Why is it important?Experimental Dermatology.  26:563-568. 2017
2017 Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signalingFree Radical Biology and Medicine.  108:918-928. 2017
2017 Skin Exposure to Ultraviolet B Rapidly Activates Systemic Neuroendocrine and Immunosuppressive ResponsesPhotochemistry and Photobiology.  93:1008-1015. 2017
2017 Vitamin D signaling and melanoma: Role of Vitamin D and its receptors in melanoma progression and managementLaboratory Investigation.  97:706-724. 2017
2017 Opportunities in Software Engineering Research for Web API Consumption 2017
2017 Glucocorticoids Inhibit Wound Healing: Novel Mechanism of ActionJournal of Investigative Dermatology.  137:1012-1014. 2017
2017 TRPM1 (melastatin) expression is an independent predictor of overall survival in clinical AJCC stage I and II melanoma patientsJournal of Cutaneous Pathology.  44:328-337. 2017
2017 Giant Basal Cell Carcinomas Express Neuroactive Mediators and Show a High Growth Rate: A Case-Control Study and Meta-Analysis of Etiopathogenic and Prognostic FactorsAmerican Journal of Dermatopathology.  39:189-194. 2017
2017 Differentiation of Keratinocytes Modulates Skin HPA AnalogJournal of Cellular Physiology.  232:154-166. 2017
2017 Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo modelsOncotarget.  8:9823-9834. 2017
2016 Bioactive forms of vitamin D selectively stimulate the skin analog of the hypothalamus-pituitary-adrenal axis in human epidermal keratinocytesMolecular and Cellular Endocrinology.  437:312-322. 2016
2016 Pregnancy-driven cardiovascular maternal miR-29 plasticity in obesityJournal of Medical Primatology.  45:297-303. 2016
2016 RORα is not a receptor for melatonin (response to DOI 10.1002/bies.201600018)BioEssays.  38:1193-1194. 2016
2016 Studying pancreas development and diabetes using human pluripotent stem cellsStem Cell Investigation.  2016. 2016
2016 Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse SpermatogenesisStem Cells.  34:2772-2783. 2016
2016 Sun-derived infrared A and ultraviolet B radiation: allies or enemies in melanomagenesis?Experimental Dermatology.  25:760-762. 2016
2016 Skin steroidogenesis in health and diseaseReviews in Endocrine and Metabolic Disorders.  17:247-258. 2016
2016 The spatiotemporal pattern of Glis3 expression indicates a regulatory function in bipotent and endocrine progenitors during early pancreatic development and in beta, PP and ductal cellsPLoS One.  11. 2016
2016 Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytesSteroids.  110:49-61. 2016
2016 Synthesis and Biological Evaluation of Vitamin D3 Metabolite 20S,23S-Dihydroxyvitamin D3 and Its 23R EpimerJournal of Medicinal Chemistry.  59:5102-5108. 2016
2016 Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetesNature Genetics.  48:519-527. 2016
2016 Hydroxylation of 20-hydroxyvitamin D3 by human CYP3A4 2016
2016 Serum Vitamin D concentrations in baboons (Papio spp.) during pregnancy and obesity 2016
2016 Classical and non-classical metabolic transformation of vitamin D in dermal fibroblastsExperimental Dermatology.  25:231-232. 2016
2016 Design, synthesis and biological activities of novel gemini 20s-hydroxyVitamin D3 analogs 2016
2016 Changes in immunogenicity during the development of urinary bladder cancer: A preliminary studyInternational Journal of Molecular Sciences.  17. 2016
2016 Development of a topical treatment for psoriasis targeting RORγ: From bench to skinPLoS One.  11. 2016
2016 Ultraviolet B stimulates proopiomelanocortin signalling in the arcuate nucleus of the hypothalamus in miceExperimental Dermatology.  25:120-123. 2016
2016 Frequency of CD4+CD25+Foxp3+ cells in peripheral blood in relation to urinary bladder cancer malignancy indicators before and after surgical removalOncotarget.  7:11450-11462. 2016
2016 Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney diseaseKidney International.  89:1307-1323. 2016
2016 Melanin content in melanoma metastases affects the outcome of radiotherapyOncotarget.  7:17844-17853. 2016
2016 RORβ and RORη expression inversely correlates with human melanoma progressionOncotarget.  7:63261-63282. 2016
2016 Role of the steroidogenic acute regulatory protein in health and diseaseEndocrine.  51:7-21. 2016
2015 Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas 2015
2015 The Concise Guide to PHARMACOLOGY 2015/16: OverviewBritish Journal of Pharmacology.  172:5729-5743. 2015
2015 Total synthesis of biologically active 20S-hydroxyvitamin D3Steroids.  104:153-162. 2015
2015 On the role of skin in the regulation of local and systemic steroidogenic activitiesSteroids.  103:72-88. 2015
2015 Expression of vitamin D receptor (VDR) positively correlates with survival of urothelial bladder cancer patientsInternational Journal of Molecular Sciences.  16:24369-24386. 2015
2015 Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl DerivativesJournal of Medicinal Chemistry.  58:7881-7887. 2015
2015 Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal glandScientific Reports.  5. 2015
2015 Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cellsBiochemical Pharmacology.  97:256-268. 2015
2015 Differential antitumor effects of vitamin D analogues on colorectal carcinoma in cultureInternational Journal of Oncology.  47:1084-1096. 2015
2015 Up-regulation of steroid biosynthesis by retinoid signaling: Implications for agingMechanisms of Ageing and Development.  150:74-82. 2015
2015 Regulation of retinoid mediated cholesterol efflux involves liver X receptor activation in mouse macrophagesBiochemical and Biophysical Research Communications.  464:312-317. 2015
2015 HECT E3 ubiquitin ligase itch functions as a novel negative regulator of Gli-similar 3 (Glis3) transcriptional activityPLoS One.  10. 2015
2015 A proposed molecular mechanism of high-dose vitamin D3 supplementation in prevention and treatment of preeclampsiaInternational Journal of Molecular Sciences.  16:13043-13064. 2015
2015 4D MRI of polycystic kidneys from rapamycin-treated Glis3-deficient miceNMR in Biomedicine.  28:546-554. 2015
2015 N1-acetyl-5-methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects 2015
2015 Ultraviolet radiation (UVR) activates central neuro-endocrine-immune system 2015
2015 When the Circadian Clock Meets the Melanin Pigmentary SystemJournal of Investigative Dermatology.  135:943-945. 2015
2015 The role of melanin pigment in melanomaExperimental Dermatology.  24:258-259. 2015
2015 Antitumor effects of vitamin D analogs on hamster and mouse melanoma cell lines in relation to melanin pigmentationInternational Journal of Molecular Sciences.  16:6645-6667. 2015
2015 Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitroMolecular and Cellular Endocrinology.  404:1-8. 2015
2015 Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γToxicology.  329:32-39. 2015
2015 On the role of the endogenous opioid system in regulating epidermal homeostasisJournal of Investigative Dermatology.  135:333-334. 2015
2015 Expression of RCAS1 correlates with urothelial bladder cancer malignancyInternational Journal of Molecular Sciences.  16:3783-3803. 2015
2015 Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolismHepatology.  61:497-505. 2015
2015 Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury 2015
2015 Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1 2015
2015 Novel activities of CYP11A1 and their potential physiological significance 2015
2015 Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation 2015
2015 Skin under the sun: When melanin pigment meets vitamin D 2015
2015 UVB activates hypothalamic-pituitary-adrenal axis in C57BL/6 miceJournal of Investigative Dermatology.  135:1638-1648. 2015
2014 The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathwaysMolecular cell biology research communications : MCBRC.  563:79-93. 2014
2014 CYP24A1 expression inversely correlates with melanoma progression: Clinic-pathological studiesInternational Journal of Molecular Sciences.  15:19000-19017. 2014
2014 Effects of in utero exposure of C57Bl/6J mice to 2,3,7,8-tetrachlorodibenzop-dioxin on epidermal permeability barrier development and functionEnvironmental Health Perspectives.  122:1052-1058. 2014
2014 Local melatoninergic system as the protector of skin integrityInternational Journal of Molecular Sciences.  15:17705-17732. 2014
2014 Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genesNucleic Acids Research.  42:10448-10459. 2014
2014 RORo: And ROR 7 are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D 2014
2014 Decreased VDR expression in cutaneous melanomas as marker of tumor progression: New data and analyses 2014
2014 Novel vitamin D analogs as potential therapeutics: Metabolism, toxicity profiling, and antiproliferative activity 2014
2014 In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal glandMolecular and Cellular Endocrinology.  383:181-192. 2014
2014 Development of a stable cell line with an intact PGC-1α/ERRα axis for screening environmental chemicalsBiochemical and Biophysical Research Communications.  444:177-181. 2014
2014 Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: Involvement of cAMP/PKA signaling 2014
2014 A novel translational model of percutaneous fetoscopic endoluminal tracheal occlusion-baboons (Papio spp.) 2014
2014 Cutaneous glucocorticosteroidogenesis: Securing local homeostasis and the skin integrityExperimental Dermatology.  23:369-374. 2014
2014 Cytochromes P450 and skin cancer: Role of local endocrine pathwaysAnti-Cancer Agents in Medicinal Chemistry.  14:77-96. 2014
2014 Lumisterol is metabolized by CYP11A1: Discovery of a new pathway 2014
2014 Melanoma resistance: A bright future for academicians and a challenge for patient advocatesMayo Clinic Proceedings.  89:429-433. 2014
2014 Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytesJournal of Pineal Research.  57:90-102. 2014
2014 Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomes 2014
2014 On the role of environmental humidity on cortisol production by epidermal keratinocytesExperimental Dermatology.  23:15-17. 2014
2014 Retinoic Acid-Related Orphan Receptor γ (RORγ): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin SensitivityPLoS Genetics.  10. 2014
2014 The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions 2014
2013 Is mc1r an important regulator of non-pigmentary responses to UV radiation?Experimental Dermatology.  22:790-791. 2013
2013 Key role of CRF in the skin stress response systemEndocrine Reviews.  34:827-884. 2013
2013 Neuro-immune-endocrine functions of the skin: An overviewExpert Review of Dermatology.  8:581-583. 2013
2013 Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesityPlacenta.  34:983-989. 2013
2013 Genetic variation of the cutaneous HPA axis: An analysis of UVB-induced differential responsesGene.  530:1-7. 2013
2013 Commentary on the practical guide for the study of sebaceous glandsExperimental Dermatology.  22:629-630. 2013
2013 Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanomaHuman Pathology.  44:2071-2074. 2013
2013 The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription 2013
2013 Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivationNucleic Acids Research.  41:6992-7008. 2013
2013 Erratum: Chemical synthesis of 20S-hydroxyvitamin D3, which shows anti-proliferative activity (Steroids (2010) 75:12 (926-935))Steroids.  78:731. 2013
2013 Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells 2013
2013 Bisphenol A affects androgen receptor function via multiple mechanismsChemico-Biological Interactions.  203:556-564. 2013
2013 Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and Mouse CYP27B1Drug Metabolism and Disposition.  41:1112-1124. 2013
2013 Targeting ALDH1A1 to treat pigmentary disordersExperimental Dermatology.  22:316-317. 2013
2013 Cyclooxygenase-2 inhibits T helper cell type 9 differentiation during allergic lung inflammation via down-regulation of IL-17RBAmerican Journal of Respiratory and Critical Care Medicine.  187:812-822. 2013
2013 Putative role of hif transcriptional activity in melanocytes and melanoma biologyDermato-Endocrinology.  5:239-251. 2013
2013 Targeted chemotherapy of metastatic melanoma: The impact of tumor cell heterogeneityExpert Review of Dermatology.  8:131-134. 2013
2013 Steroidogenesis in the skin: Implications for local immune functions 2013
2013 CD44 Plays a Critical Role in Regulating Diet-Induced Adipose Inflammation, Hepatic Steatosis, and Insulin ResistancePLoS One.  8. 2013
2013 Expression of the vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progressionHuman Pathology.  44:374-387. 2013
2013 Ultraviolet radiation regulates cortisol activity in a waveband-dependent manner in human skin ex vivoBritish Journal of Dermatology.  168:595-601. 2013
2013 Retinoic acid-related orphan receptors α and γ: Key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivityFrontiers in Endocrinology.  4. 2013
2013 20S-hydroxyvitamin D3, noncalcemic product of CYP11A1 action on vitamin D3, exhibits potent antifibrogenic activity in vivoJournal of Clinical Endocrinology and Metabolism.  98. 2013
2013 Effects of sidechain length and composition on the kinetic conversion and product distribution of vitamin D analogs determined by real-time NMRDermato-Endocrinology.  5:142-149. 2013
2013 NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanomaClinical and Experimental Metastasis.  30:25-36. 2013
2013 Novel vitamin D photoproducts and their precursors in the skinDermato-Endocrinology.  5:7-19. 2013
2012 Rat CYP24A1 acts on 20-hydroxyvitamin D3 producing hydroxylated products with increased biological activityBiochemical Pharmacology.  84:1696-1704. 2012
2012 Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes 2012
2012 RAP80 is critical in maintaining genomic stability and suppressing tumor developmentCancer Research.  72:5080-5090. 2012
2012 Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strengthMolecular and Cellular Endocrinology.  361:143-152. 2012
2012 In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1 2012
2012 Novel vitamin D hydroxyderivatives inhibit melanoma growth and show differential effects on normal melanocytes 2012
2012 RORγ directly regulates the circadian expression of clock genes and downstream targets in vivoNucleic Acids Research.  40:8519-8535. 2012
2012 Role of TRPM in melanocytes and melanomaExperimental Dermatology.  21:650-654. 2012
2012 Glis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6Molecules and Cells.  34:193-200. 2012
2012 Robust tumor immunity to melanoma mediated by interleukin-9-producing T cellsNature Medicine.  18:1248-1253. 2012
2012 Sensing the environment: Regulation of localand global homeostasis by the skin's neuroendocrine systemAdvances in anatomy, embryology, and cell biology.  212:1-115. 2012
2012 KU812 basophils express urocortin, CRH-R, MC1R and steroidogenic enzymes and secrete progesteroneExperimental Dermatology.  21:541-543. 2012
2012 New vitamin D analogs as potential therapeutics in melanoma 2012
2012 Design, synthesis, and biological action of 20 R -hydroxyvitamin D3Journal of Medicinal Chemistry.  55:3573-3577. 2012
2012 Melatonin membrane receptors in peripheral tissues: Distribution and functionsMolecular and Cellular Endocrinology.  351:152-166. 2012
2012 Metabolism of cholesterol, vitamin D3 and 20-hydroxyvitamin D3 incorporated into phospholipid vesicles by human CYP27A1 2012
2012 Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γToxicology and Applied Pharmacology.  259:338-345. 2012
2012 20-Hydroxyvitamin D 3 inhibits proliferation of cancer cells with high efficacy while being non-toxic 2012
2012 Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterolDrug Metabolism and Disposition.  40:436-444. 2012
2012 Stress-linked cortisol concentrations in hair: What we know and what we need to knowReviews in the Neurosciences.  23:111-121. 2012
2012 Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2Immunity.  36:23-31. 2012
2012 Gli-Similar Proteins. Their Mechanisms of Action, Physiological Functions, and Roles in Disease 2012
2012 L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functionsPigment Cell and Melanoma Research.  25:14-27. 2012
2012 Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesisCancer Research.  72:133-143. 2012
2011 High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivativesBritish Journal of Cancer.  105:1874-1884. 2011
2011 Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programsHuman Molecular Genetics.  20:4155-4166. 2011
2011 Scalp nodule on a middle-aged womanClinical and Experimental Dermatology.  36:818-819. 2011
2011 Cutaneous hypothalamic-pituitary-adrenal axis homolog: Regulation by ultraviolet radiation 2011
2011 Production of 22-hydroxy metabolites of vitamin D 3 by cytochrome P450scc (CYP11A1) and analysis of their biological activities on skin cellsDrug Metabolism and Disposition.  39:1577-1588. 2011
2011 Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammationAmerican Journal of Respiratory and Critical Care Medicine.  184:37-49. 2011
2011 Transcriptional profiling reveals a role for RORα in regulating gene expression in obesity-associated inflammation and hepatic steatosisPhysiological Genomics.  43:818-828. 2011
2011 Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of FusedJournal of Biological Chemistry.  286:22077-22089. 2011
2011 Melanoma update: Diagnostic and prognostic factors that can effectively shape and personalize managementBiomarkers in Medicine.  5:333-360. 2011
2011 Retinoic acid-related orphan receptor γ directly regulates neuronal PAS domain protein 2 transcription in vivoNucleic Acids Research.  39:4769-4782. 2011
2011 Expression of vitamin D receptor decreases during progression of pigmented skin lesionsHuman Pathology.  42:618-631. 2011
2011 Immunology: A helping hand against autoimmunityNature.  472:421-422. 2011
2011 Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency 2011
2011 20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells 2011
2011 Identification of nuclear localization, DNA binding, and transactivating mechanisms of krüppel-like zinc finger protein gli-similar 2 (Glis2)Journal of Biological Chemistry.  286:4749-4759. 2011
2011 Acquired primary cutaneous ganglioneuroma with adipocytic metaplasia: "An end point of melanocytic 'maturation'?" A case report and meta-analysis with comparison to a cross-sectional study of neurotized melanocytic neviAmerican Journal of Dermatopathology.  33:17-26. 2011
2011 Lineage-specific effects of 1,25-dihydroxyvitamin D3 on the development of effector CD4 T cellsJournal of Biological Chemistry.  286:997-1004. 2011
2011 Neuroendocrinology of the skin: An overview and selective analysisDermato-Endocrinology.  3:3-10. 2011
2011 Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistanceDiabetes.  60:177-188. 2011
2011 Regulated proenkephalin expression in human skin and cultured skin cellsJournal of Investigative Dermatology.  131:613-622. 2011
2011 Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5, 7-dien-20-one to novel secosteroids that show anti-melanoma activitySteroids.  76:193-203. 2011
2011 Vitamin D analogs 17,20S(OH) 2 pD and 17,20R(OH) 2 pD are noncalcemic and exhibit antifibrotic activityJournal of Investigative Dermatology.  131:1167-1169. 2011
2010 Erratum: A new steroidal 5,7-diene derivative, 3β-hydroxyandrosta-5,7- diene-17β-carboxylic acid, shows potent anti-proliferative activity (Steroids (2010) 75:3 (230-239))Steroids.  75:1164. 2010
2010 Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activitySteroids.  75:926-935. 2010
2010 Products of vitamin D3 or 7-dehydrocholesterol metabolism by Cytochrome P450scc show anti- leukemia effects, having low or absent calcemic activityPLoS One.  5. 2010
2010 Gli-similar (Glis) Krüppel-like zinc finger proteins: Insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease 2010
2010 Nicotinic receptor signaling in nonexcitable epithelial cells: Paradigm shifting from ion current to kinase cascade. Focus on "Upregulation of nuclear factor-κB expression by SLURP-1 is mediated by α 7-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases" 2010
2010 The potential role of vitamin D in the progression of benign and malignant melanocytic neoplasmsExperimental Dermatology.  19:860-864. 2010
2010 Altered cerebellar development in nuclear receptor TAK1/TR4 null mice is associated with deficits in GLAST+ Glia, alterations in social behavior, motor learning, startle reactivity, and microglia 2010
2010 Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1α,20,23-trihydroxyvitamin D3, which has altered biological activityDrug Metabolism and Disposition.  38:1553-1559. 2010
2010 Immuno-histochemical evaluation of solar lentigines: The association of KGF/KGFR and other factors with lesion developmentJournal of Dermatological Science.  59:91-97. 2010
2010 The role of constitutively activated STAT3 in B16 melanoma cellsInternational Journal of Interferon, Cytokine and Mediator Research.  2:1-7. 2010
2010 IκBη regulates TH 17 development by cooperating with ROR nuclear receptorsNature.  464:1381-1385. 2010
2010 20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-κB activity in human keratinocytesJournal of Cellular Physiology.  223:36-48. 2010
2010 Transcription factor glis3, a novel critical player in the regulation of pancreatic β-cell development and insulin gene expression (Molecular and Cellular Biology (2009) 29, 24, (6366-6379))Molecular and Cellular Biology.  30:1964. 2010
2010 The correlation of TRPM1 (Melastatin) mRNA expression with microphthalmia-associated transcription factor (MITF) and other melanogenesis-related proteins in normal and pathological skin, hair follicles and melanocytic neviJournal of Cutaneous Pathology.  37:26-40. 2010
2010 A new steroidal 5,7-diene derivative, 3β-hydroxyandrosta-5,7-diene-17β-carboxylic acid, shows potent anti-proliferative activitySteroids.  75:230-239. 2010
2010 Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathwaysExperimental Cell Research.  316:507-516. 2010
2010 Molecular mechanisms involved in farnesol-induced apoptosisCancer Letters.  287:123-135. 2010
2010 Emerging role of alternative splicing of CRF1 receptor in CRF signalingActa Biochimica Polonica.  57:1-13. 2010
2010 Stress and the skinGiornale Italiano di Dermatologia e Venereologia.  145:213-220. 2010
2009 Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiationJournal of Biological Chemistry.  284:35283-35286. 2009
2009 Transcription factor glis3, a novel critical player in the regulation of pancreatic β-cell development and insulin gene expressionMolecular and Cellular Biology.  29:6366-6379. 2009
2009 Id2-, RORγt-, and LTβR-independent initiation of lymphoid organogenesis in ocular immunityJournal of Experimental Medicine.  206:2351-2364. 2009
2009 Neuroendocrine activity of the melanocyteExperimental Dermatology.  18:760-763. 2009
2009 What are melanocytes really doing all day long...?Experimental Dermatology.  18:799-819. 2009
2009 The melatonin-producing system is fully functional in retinal pigment epithelium (ARPE-19)Molecular and Cellular Endocrinology.  307:211-216. 2009
2009 A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damageJournal of Biological Chemistry.  284:19280-19289. 2009
2009 20-hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-κB activity by increasing IκBα levels in human keratinocytesPLoS One.  4. 2009
2009 Phenylmethimazole decreases toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migrationClinical Cancer Research.  15:4114-4122. 2009
2009 Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney diseaseMolecular and Cellular Biology.  29:2556-2569. 2009
2009 Human female hair follicles are a direct, nonclassical target for thyroid-stimulating hormoneJournal of Investigative Dermatology.  129:1126-1139. 2009
2009 Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 SignalingImmunity.  30:576-587. 2009
2009 Are suberythemal doses of ultraviolet B good for your skin?Pigment Cell and Melanoma Research.  22:154-155. 2009
2009 Identification of human CYP2C8 as a retinoid-related orphan nuclear receptor target geneJournal of Pharmacology and Experimental Therapeutics.  329:192-201. 2009
2009 Metabolism of vitamin D2 to 17,20,24-trihydroxyvitamin D2 by cytochrome P450scc (CYP11A1)Drug Metabolism and Disposition.  37:761-767. 2009
2009 High-resolution magic angle spinning nuclear magnetic resonance analysis of metabolic changes in melanoma cells after induction of melanogenesisAnalytical Biochemistry.  386:282-284. 2009
2009 Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cellsInternational Journal of Cancer.  124:1470-1477. 2009
2009 CRF1 receptor splicing in epidermal keratinocytes: Potential biological role and environmental regulationsJournal of Cellular Physiology.  218:593-602. 2009
2009 On the role of the corticotropin-releasing hormone signalling system in the aetiology of inflammatory skin disordersBritish Journal of Dermatology.  160:229-232. 2009
2009 Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3β, 17α, 20-triol and their bioactivity in melanoma cellsSteroids.  74:218-228. 2009
2009 Modulation of corticotropin releasing factor (CRF) signaling through receptor splicing in mouse pituitary cell line AtT-20--emerging role of soluble isoforms. 2009
2009 New techniques in dermatopathology that help to diagnose and prognosticate melanomaClinics in Dermatology.  27:75-102. 2009
2009 Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism.Nuclear Receptor Signaling.  7. 2009
2009 Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skinPLoS One.  4:1-18. 2009
2008 CCR6 regulates the migration of inflammatory and regulatory T cellsJournal of Immunology.  181:8391-8401. 2008
2008 Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesisBiochemical Journal.  416:347-355. 2008
2008 Metabolism of 1α-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1α,20-dihydroxyvitamin D3 2008
2008 Volar melanotic macules in a gardener: A case report and review of the literatureAmerican Journal of Dermatopathology.  30:612-619. 2008
2008 RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sitesCancer Letters.  271:179-190. 2008
2008 Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomesJournal of Pineal Research.  45:515-523. 2008
2008 Current concepts of metastasis in melanomaExpert Review of Dermatology.  3:569-585. 2008
2008 The emerging role of nuclear receptor RORα and its crosstalk with LXR in xeno- and endobiotic gene regulationExperimental Biology and Medicine.  233:1191-1201. 2008
2008 Inhibition of melanogenesis as a radiation sensitizer for melanoma therapyInternational Journal of Cancer.  123:1448-1456. 2008
2008 Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages (DOI:10.1016/j.immuni.2008.05.009)Immunity.  29:318. 2008
2008 Melatonin as a major skin protectant: From free radical scavenging to DNA damage repairExperimental Dermatology.  17:713-730. 2008
2008 Cooling skin cancer: Menthol inhibits melanoma growth. Focus on "TRPM8 activation suppresses cellular viability in human melanoma" 2008
2008 Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell LineagesImmunity.  29:138-149. 2008
2008 Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell ProgramsImmunity.  29:44-56. 2008
2008 NF-κB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathwayJournal of Biological Chemistry.  283:16391-16399. 2008
2008 Kinetics of vitamin D3 metabolism by cytochrome P450scc (CYP11A1) in phospholipid vesicles and cyclodextrin 2008
2008 RAP80 responds to DNA damage induced by both ionizing radiation and UV irradiation and is phosphorylated at Ser205Cancer Research.  68:4269-4276. 2008
2008 Skin as an endocrine organ: implications for its functionDrug Discovery Today: Disease Mechanisms.  5. 2008
2008 Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytesJournal of Pineal Research.  44:397-407. 2008
2008 Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc 2008
2008 Krüppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functionsMolecular and Cellular Biology.  28:2358-2367. 2008
2008 The skin as a mirror of the soul: Exploring the possible roles of serotoninExperimental Dermatology.  17:301-311. 2008
2008 Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)Nucleic Acids Research.  36:1690-1702. 2008
2008 Identification of oxysterol 7α-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor α (RORα) (NR1F1) target gene and a functional cross-talk between RORα and liver X receptor (NR1H3)Molecular Pharmacology.  73:891-899. 2008
2008 Viewpoint 4Experimental Dermatology.  17:148-150. 2008
2008 Vitiligo pathogenesis: Autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?Experimental Dermatology.  17:139-140. 2008
2008 T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγImmunity.  28:29-39. 2008
2008 20-Hydroxyvitamin D3, a product of vitamin D3 hydroxylation by cytochrome P450scc, stimulates keratinocyte differentiationJournal of Investigative Dermatology.  128:2271-2280. 2008
2008 John Martin Wood (1938-2008)--pioneering biochemist, educator and communicator.Experimental Dermatology.  17:579-583. 2008
2008 Melatonin and the hair follicleJournal of Pineal Research.  44:1-15. 2008
2008 Melatonin in the skin: synthesis, metabolism and functions.Trends in Endocrinology and Metabolism.  19:17-24. 2008
2008 Regulation of the vitamin D receptor and cornifin beta expression in vaginal epithelium of the rats through vitamin D3European Journal of Histochemistry.  52:107-114. 2008
2008 Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives 2008
2008 Thyroid hormones directly alter human hair follicle functions: Anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentationJournal of Clinical Endocrinology and Metabolism.  93:4381-4388. 2008
2007 A nervous breakdown in the skin: Stress and the epidermal barrierJournal of Clinical Investigation.  117:3166-3169. 2007
2007 Gene expression profiling reveals a regulatory role for RORα and RORγ in phase I and phase II metabolismPhysiological Genomics.  31:281-294. 2007
2007 RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylationBiochemical and Biophysical Research Communications.  362:132-138. 2007
2007 Melanocyte Receptors: Clinical Implications and Therapeutic RelevanceDermatologic Clinics.  25:541-557. 2007
2007 Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress responseCancer Research.  67:7929-7936. 2007
2007 Does p53 regulate skin pigmentation by controlling proopiomelanocortin gene transcription? [3]Pigment Cell and Melanoma Research.  20:307-308. 2007
2007 Mechanism of UV-related carcinogenesis and its contribution to nevi/melanomaExpert Review of Dermatology.  2:451-469. 2007
2007 Essential autocrine regulation by IL-21 in the generation of inflammatory T cellsNature.  448:480-483. 2007
2007 The ubiquitin-interacting motif-containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair responseCancer Research.  67:6647-6656. 2007
2007 Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis 2007
2007 Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epitheliumJournal of Endocrinology.  193:157-169. 2007
2007 Molecular cloning and initial characterization of African green monkey (Cercopithecus aethiops) corticotropin releasing factor receptor type 1 (CRF1) from COS-7 cellsGene.  389:154-162. 2007
2007 The Krüppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/β-catenin signaling pathwayFEBS Letters.  581:858-864. 2007
2007 Immunohistochemical detection and distribution of cornifin α and vitamin D receptor expression in vaginal epithelium treated with vitamin D 3 2007
2007 Retinoid-related orphan receptor γ controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergenJournal of Immunology.  178:3208-3218. 2007
2007 Structure-activity relationship studies of arylthiazolidine amides as selective cytotoxic agents for melanoma 2007
2007 The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression systemPharmacogenetics and Genomics.  17:169-180. 2007
2007 Ubiquitin-interaction motifs of RAP80 are critical in its regulation of estrogen receptor αNucleic Acids Research.  35:1673-1686. 2007
2007 Differential expression of HPA axis homolog in the skinMolecular and Cellular Endocrinology.  265-266:143-149. 2007
2007 Epidermodysplasia verruciformis and cutaneous human papillomavirus DNA, but not genital human papillomavirus DNAs, are frequently detected in vulvar and vaginal melanomaAmerican Journal of Dermatopathology.  29:13-17. 2007
2007 Erratum: Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems (FASEB Journal DOI: 10.1096/fj.05-5227fje) 2007
2007 CRH mediates inflammation induced by lipopolysaccharide in human adult epidermal keratinocytes [4]Journal of Investigative Dermatology.  127:730-732. 2007
2007 Krüppel-like zinc finger protein Glis3 promotes osteoblast differentiation by regulating FGF18 expressionJournal of Bone and Mineral Research.  22:1234-1244. 2007
2007 Viewpoint 4Experimental Dermatology.  16:59-61. 2007
2007 What are subcutaneous adipocytes really good for...?Experimental Dermatology.  16:45-47. 2007
2006 Modulatory role for retinoid-related orphan receptor α in allergen-induced lung inflammationAmerican Journal of Respiratory and Critical Care Medicine.  174:1299-1309. 2006
2006 CRH inhibits NF-κB signaling in human melanocytesRegulatory Peptides.  27:3276-3283. 2006
2006 Retinoid-related orphan receptors (RORs): Roles in cellular differentiation and developmentAdvances in developmental biology (Amsterdam, Netherlands).  16:313-355. 2006
2006 Characterization of a ultraviolet B-induced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes 2006
2006 Molecular spectrum of pigmented skin lesions: From nevus to melanomaExpert Review of Dermatology.  1:679-700. 2006
2006 Erratum: An alternative pathway of vitamin D2 metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D 2 and 17,20-dihydroxyvitamin D2 (FEBS Journal (2006) 273 (2891-2901)) 2006
2006 An alternative pathway of vitamin D2 metabolism: Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2 2006
2006 NABP1, a novel RORγ-regulated gene encoding a single-stranded nucleic-acid-binding proteinBiochemical Journal.  397:89-99. 2006
2006 Cultured human dermal fibroblasts do produce cortisol [1]Journal of Investigative Dermatology.  126:1177-1178. 2006
2006 Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides 2006
2006 CRH functions as a growth factor/cytokine in the skinJournal of Cellular Physiology.  206:780-791. 2006
2006 Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems 2006
2006 Corticotropin releasing hormone and the skinFrontiers in Bioscience-Landmark.  11:2230-2248. 2006
2006 Erratum: CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH (American Journal of Physiology - Endocrinology and Metabolism (April 2005) 2000,51, (E701-E706)) 2006
2006 Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosisJournal of Pineal Research.  40:18-26. 2006
2006 Neuroimmunology of stress: Skin takes center stageJournal of Investigative Dermatology.  126:1697-1704. 2006
2006 Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell linesInternational Journal of Oncology.  29:665-672. 2006
2006 Proopiomelanocortin signaling system is operating in mast cellsJournal of Investigative Dermatology.  126:1934-1936. 2006
2006 Regulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermisJournal of Investigative Dermatology.  126:49-60. 2006
2005 Krüppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1)Nucleic Acids Research.  33:6805-6815. 2005
2005 Neuroendocrine system of the skin 2005
2005 Enzymatic metabolism of ergosterol by cytochrome P450scc to biologically active 17α,24-dihydroxyergosterolCell chemical biology.  12:931-939. 2005
2005 The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism 2005
2005 A novel metabolic pathway of melatonin: Oxidation by cytochrome cBiochemistry.  44:9300-9307. 2005
2005 Enhanced susceptibility of staggerer (RORαsg/sg) mice to lipopolysaccharide-induced lung inflammation 2005
2005 CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH 2005
2005 Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermisJournal of Cellular Physiology.  203:118-126. 2005
2005 Corticotropin-releasing hormone triggers differentiation in HaCaT keratinocytesBritish Journal of Dermatology.  152:474-480. 2005
2005 Preservation of eumelanin hair pigmentation in proopiomelanocortin- deficient mice on a nonagouti (a/a) genetic background 2005
2005 The cutaneous serotoninergic/melatoninergic system: Securing a place under the sun 2005
2005 Biomarkers in melanoma: Stage III and IV disease 2005
2005 CRH stimulates POMC activity and corticosterone production in dermal fibroblastsJournal of Neuroimmunology.  162:97-102. 2005
2005 Hair follicle pigmentationJournal of Investigative Dermatology.  124:13-21. 2005
2005 Molecular diagnostics in melanomaJournal of the American Academy of Dermatology.  52:743-775. 2005
2005 On the role of melatonin in skin physiology and pathologyEndocrine.  27:137-147. 2005
2005 Splenic eumelanin differs from hair eumelanin in C57BL/6 miceActa Biochimica Polonica.  52:433-441. 2005
2004 Recent advances in the mechanisms of action and physiological functions of the retinoid-related orphan receptors (RORs) 2004
2004 A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin 2004
2004 A novel microarray to evaluate stress-related genes in skin: Effect of ultraviolet light radiationGene.  341:199-207. 2004
2004 Expression of genes coding melatonin and serotonin receptors in rodent skin 2004
2004 Melanin pigmentation in mammalian skin and its hormonal regulationPhysiological Reviews.  84:1155-1228. 2004
2004 TIP27: A novel repressor of the nuclear orphan receptor TAK1/TR4Nucleic Acids Research.  32:4194-4204. 2004
2004 Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium 2004
2004 Inhibition of melanoma metastases by fenofibrateArchives of Dermatological Research.  296:54-58. 2004
2004 Molecular and functional characterization of novel CRFR1 isoforms from the skin 2004
2004 Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORγBiochemical and Biophysical Research Communications.  315:919-927. 2004
2004 Differential Expression of a Cutaneous Corticotropin-Releasing Hormone System 2004
2004 Corticotropin-releasing hormone stimulates NF-κB in human epidermal keratinocytesJournal of Endocrinology.  181. 2004
2004 Serotonin metabolism in rat skin: Characterization by liquid chromatography-mass spectrometryMolecular cell biology research communications : MCBRC.  421:61-66. 2004
2004 Tsp57: A Novel Gene Induced during a Specific Stage of SpermatogenesisBiology of Reproduction.  70:106-113. 2004
2003 Tryptophan hydroxylase expression in human skin cells 2003
2003 GLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functionsNucleic Acids Research.  31:5513-5525. 2003
2003 Characterization of the serotoninergic system in the C57BL/6 mouse skin 2003
2003 Transplantable melanomas in gerbils (meriones unguiculatus). II: MelanogenesisExperimental Dermatology.  12:356-364. 2003
2003 Functional activity of serotoninergic and melatoninergic systems expressed in the skinJournal of Cellular Physiology.  196:144-153. 2003
2003 β-Endorphin/μ-opiate receptor system in the skinJournal of Investigative Dermatology.  120. 2003
2003 Analysis of germ cell nuclear factor transcripts and protein expression during spermatogenesisBiology of Reproduction.  68:1620-1630. 2003
2003 Biomarkers in melanoma: Staging, prognosis and detection of early metastases 2003
2003 Intracellular calcium measurements of single human skin cells after stimulation with corticotropin-releasing factor and urocortin using confocal laser scanning microscopyJournal of Cell Science.  116:1261-1268. 2003
2003 Dual activation of PPARα and PPARγ by mono-(2-ethylhexyl) phthalate in rat ovarian granulosa cellsMolecular and Cellular Endocrinology.  201:133-141. 2003
2003 Biomarkers in melanoma: Predisposition, screening and diagnosis 2003
2003 Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoidsMolecular Pharmacology.  63:557-564. 2003
2003 Cutaneous metabolism of vitamin B-6Journal of Investigative Dermatology.  120:292-300. 2003
2003 Corticotropin-Releasing Hormone Inhibits Nuclear Factor-κB Pathway in Human HaCaT KeratinocytesJournal of Investigative Dermatology.  121:1496-1499. 2003
2003 Malignant melanoma 2003: predisposition, diagnosis, prognosis, and staging.American Journal of Clinical Pathology.  120 Suppl. 2003
2003 Self-regulated endocrine systems in the skin. 2003
2003 What are the clinicopathologic features of matricoma? [2]American Journal of Dermatopathology.  25:446-447. 2003
2002 Retinoid-related orphan receptors (RORs): Roles in cell survival, differentation and diseaseCell Death and Differentiation.  9:1167-1171. 2002
2002 RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptorJournal of Biological Chemistry.  277:32379-32388. 2002
2002 Identification of Glis1, a novel Gli-related, Krüppel-like zinc finger protein containing transactivation and repressor functionsJournal of Biological Chemistry.  277:30901-30913. 2002
2002 Coming of age of melanogenesis-related proteinsArchives of Pathology and Laboratory Medicine.  126:775-777. 2002
2002 Erratum: Neuroendocrinology of the skin (Endocrine Reviews (2000) 21 (457-487))Endocrine Reviews.  23:364. 2002
2002 Overexpression of mucin genes induced by interleukin-1β, tumor necrosis factor-α, lipopolysaccharide, and neutrophil elastase is inhibited by a retinoic acid receptor α antagonistExperimental Lung Research.  28:315-332. 2002
2002 Possible mechanisms of hypopigmentation in lichen sclerosusAmerican Journal of Dermatopathology.  24:97-107. 2002
2002 Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesisJournal of Biological Chemistry.  277:10139-10149. 2002
2002 High incidence of T-cell lymphomas in mice deficient in the retinoid-related orphan receptor RORγCancer Research.  62:901-909. 2002
2002 Conversion of L-tryptophan to serotonin and melatonin in human melanoma cellsFEBS Letters.  511:102-106. 2002
2002 Melanocytic proliferations associated with lichen sclerosusJAMA Dermatology.  138:77-87. 2002
2002 Corticotropin-releasing hormone affects cytokine production in human HaCaT keratinocytesLife Sciences.  70:1013-1021. 2002
2002 Characterization of the expression of the retinoid-related, testis-associated receptor (RTR) in trophoblastsPlacenta.  23:281-287. 2002
2002 Corticotropin releasing factor receptor type 1: Molecular cloning and investigation of alternative splicing in the hamster skinJournal of Investigative Dermatology.  118:1065-1072. 2002
2002 Expression of hypothalamic-pituitary-thyroid axis related genes in the human skinJournal of Investigative Dermatology.  119:1449-1455. 2002
2002 Gas chromatography/mass spectrometry characterization of corticosteroid metabolism in human immortalized keratinocytesJournal of Investigative Dermatology.  118:310-315. 2002
2002 Serotoninergic and melatoninergic systems are fully expressed in human skin. 2002
2002 Serotoninergic system in hamster skinJournal of Investigative Dermatology.  119:934-942. 2002
2001 Microassay of phosphate provides a general method for measuring the activity of phosphatases using physiological, nonchromogenic substrates such as lysophosphatidic acidAnalytical Biochemistry.  298:241-245. 2001
2001 Genomic structure of the gene encoding the human GLI-related, Krüppel-like zinc finger protein GLIS2Gene.  280:49-57. 2001
2001 Malignant melanoma.Archives of Pathology and Laboratory Medicine.  125:1295-1306. 2001
2001 Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors 2001
2001 Human keratinocytes express functional α-MSH (MC1-R) receptors [2] 2001
2001 Inhibition of mouse melanoma cell proliferation by corticotropin-releasing hormone and its analogs 2001
2001 Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2Cell Death and Differentiation.  8:411-424. 2001
2001 Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression. 2001
2001 Decreased growth inhibitory responses of squamous carcinoma cells to interferon-γ involve failure to recruit cki proteins into cdk2 complexesJournal of Investigative Dermatology.  117:1274-1281. 2001
2001 Malignant melanoma: An updateArchives of Pathology and Laboratory Medicine.  125:1295-1306. 2001
2001 Pleiotropic effects of corticotropin releasing hormone on normal human skin keratinocytes 2001
2001 Pleiotropic effects of corticotropin releasing hormone on normal human skin keratinocytes. 2001
2001 Role of molecular biology in diagnostic pathology of melanoma.Methods in Molecular Medicine.  61:123-163. 2001
2001 Steroidogenesis in the human skin: 21-hydroxylation in cultured keratinocytes 2001
2001 TNF-α inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPβ and δEndocrine Journal.  48:249-253. 2001
2000 Controversies in experimental dermatology. What is the most promising strategy for the treatment of metastasizing melanoma? CommentariesExperimental Dermatology.  9:445-451. 2000
2000 The skin produces urocortinJournal of Clinical Endocrinology and Metabolism.  85:815-823. 2000
2000 What is the most promising strategy for the treatment of metastasizing melanoma?Experimental Dermatology.  9:439-451. 2000
2000 Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factorJournal of Biological Chemistry.  275:35077-35085. 2000
2000 Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis 2000
2000 Active steroidogenesis in the normal rat skin 2000
2000 Corticotropin releasing hormone and related peptides can act as bioregulatory factors in human keratinocytes 2000
2000 Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stressPhysiological Reviews.  80:979-1020. 2000
2000 Experimental ruthenium plaque therapy of amelanotic and melanotic melanomas in the hamster eye 2000
2000 Human skin expresses growth hormone but not the prolactin gene 2000
2000 Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cellsMolecular Pharmacology.  58:483-490. 2000
2000 Liquid chromatography-mass spectrometry detection of corticotropin-releasing hormone and proopiomelanocortin-derived peptides in human skinJournal of Clinical Endocrinology and Metabolism.  85:3582-3588. 2000
2000 Neuroendocrinology of the skinEndocrine Reviews.  21:457-487. 2000
2000 Spatiotemporal expression, distribution, and processing of POMC and POMC-derived peptides in murine skin 2000
1999 Molecular pathology of soft tissue and bone tumors: A reviewArchives of Pathology and Laboratory Medicine.  123:1246-1259. 1999
1999 The proopiomelanocortin system in cutaneous neuroimmunomodulation. An introductory overview.Annals of the New York Academy of Sciences.  885. 1999
1999 Regulation of cyclooxygenase-2 by interferon γ and transforming growth factor α in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinasesJournal of Biological Chemistry.  274:29138-29148. 1999
1999 B-chain sequence and in situ hybridization of the rabbit placental relaxin-like gene productBiology of Reproduction.  61:527-532. 1999
1999 Melanocytic matricoma: A report of two cases of a new entityAmerican Journal of Dermatopathology.  21:344-349. 1999
1999 Metabolism of progesterone to DOC, corticosterone and 18OHDOC in cultured human melanoma cellsFEBS Letters.  455:364-366. 1999
1999 Decreased expression of retinoic acid receptors, transforming growth factor β, involucrin, and cornifin in cervical intraepithelial neoplasiaClinical Cancer Research.  5:1503-1508. 1999
1999 Post-transcriptional regulation of MyD118 and GADD45 in human lung carcinoma cells during 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid-induced apoptosisMolecular Pharmacology.  55:668-676. 1999
1999 Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cellsBiochemical Journal.  338:351-357. 1999
1999 Down-regulation of the expression of O-acetyl-GD3 by the O- acetylesterase cDNA in hamster melanoma cells: Effects on cellular proliferation, differentiation, and melanogenesisJournal of Neurochemistry.  72:954-961. 1999
1999 Regulation of the transglutaminase I gene. Identification of DNA elements involved in its transcriptional control in tracheobronchial epithelial cellsJournal of Biological Chemistry.  274:3887-3896. 1999
1999 Correlation between expression of peroxisome proliferator-activated receptor β and squamous differentiation in epidermal and tracheobronchial epithelial cellsMolecular and Cellular Endocrinology.  147:85-92. 1999
1999 ACTH production in C57BL/6 mouse skinAnnals of the New York Academy of Sciences.  885:448-450. 1999
1999 Cloning and characterization of KPL2, a novel gene induced during ciliogenesis of tracheal epithelial cellsAmerican Journal of Respiratory Cell and Molecular Biology.  20:675-683. 1999
1999 Differential temporal and spatial expression of POMC mRNA and of the production of POMC peptides during the murine hair cycleAnnals of the New York Academy of Sciences.  885:427-429. 1999
1999 Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patientsHuman Pathology.  30:208-215. 1999
1999 Modification of melanogenesis in cultured human melanoma cells [6] 1999
1999 Regulation of guanylate-binding protein expression in interferon-γ- treated human epidermal keratinocytes and squamous cell carcinoma cellsJournal of Investigative Dermatology.  112:977-983. 1999
1999 Restoration of the mucous phenotype by retinoic acid in retinoid-deficient human bronchial cell cultures: Changes in mucin gene expressionAmerican Journal of Respiratory Cell and Molecular Biology.  20:43-52. 1999
1999 UV light and MSH receptorsAnnals of the New York Academy of Sciences.  885:100-116. 1999
1999 What's the use of generating melanin?Experimental Dermatology.  8:153-164. 1999
1998 Hair cycle-dependent production of ACTH in mouse skin 1998
1998 Characterization of corticotropin-releasing hormone (CRH) in human skinJournal of Clinical Endocrinology and Metabolism.  83:1020-1024. 1998
1998 Effect of CRF and related peptides on calcium signaling in human and rodent melanoma cellsFEBS Letters.  435:187-190. 1998
1998 Inhibition of melanogenesis as an adjuvant strategy in the treatment of melanotic melanomas: Selective review and hypothesis 1998
1998 Dermatofibrosarcoma protuberans can induce epidermal hyperplasia that is inversely related to its proximity to the epidermis [1] (multiple letters)American Journal of Dermatopathology.  20:428-430. 1998
1998 Induction of the nuclear orphan receptor RORγ during adipocyte differentiation of D1 and 3T3-L1 cellsMolecular Cancer Research.  9:267-276. 1998
1998 Animals under the sun: Effects of ultraviolet radiation on mammalian skinClinics in Dermatology.  16:503-515. 1998
1998 Cutaneous immunomodulation and coordination of skin stress responses by α-melanocyte-stimulating hormone AAnnals of the New York Academy of Sciences.  840:381-394. 1998
1998 Expression of germ cell nuclear factor (GCNF/RTR) during spermatogenesis.Molecular Reproduction and Development.  50:93-102. 1998
1998 Regulation of peroxisome proliferator-activated receptor α-induced transactivation by the nuclear orphan receptor TAK1/TR4Journal of Biological Chemistry.  273:10948-10957. 1998
1998 Expression of germ cell nuclear factor (GCNF/RTR) during spermatogenesisMolecular Reproduction and Development.  50:93-102. 1998
1998 Suppression of relaxin gene expression by retinoids in squamous differentiated rabbit tracheal epithelial cellsMolecular and Cellular Endocrinology.  138:115-125. 1998
1998 Differentiation-dependent regulation of retinal dehydrogenase gene expression in the tracheaBiochemistry and Cell Biology.  76:59-62. 1998
1998 Hair cycle-dependent expression of corticotropinreleasing factor (CRF) and CRF receptors in murine skin 1998
1998 Identification of β-endorphin, α-MSH and ACTH peptides in cultured human melanocytes, melanoma and squamous cell carcinoma cells by RP-HPLCExperimental Dermatology.  7:213-216. 1998
1998 Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathwaysCell Death and Differentiation.  5:973-983. 1998
1998 Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cellsAmerican Journal of Respiratory Cell and Molecular Biology.  18:323-333. 1998
1998 Inhibition of melanogenesis as an adjuvant strategy in the treatment of melanotic melanomas: selective review and hypothesis. 1998
1998 Molecular pathology of malignant melanomaAmerican Journal of Clinical Pathology.  110:788-794. 1998
1998 Up-regulation of p27(Kip1), p21(WAF1/Cip1) and p16(Ink4a) is associated with, but not sufficient for, induction of squamous differentiationJournal of Cell Science.  111:1185-1196. 1998
1998 What controls melanogenesis?Experimental Dermatology.  7:143-150. 1998
1997 Retinoids and ApoptosisAdvances in Organ Biology.  3:161-196. 1997
1997 Genomic structure and chromosomal mapping of the nuclear orphan receptor RORγ (RORC) geneGenomics.  46:93-102. 1997
1997 Identification and measurement of β-endorphin levels in the skin during induced hair growth in mice 1997
1997 Characterization of the response element and DNA binding properties of the nuclear orphan receptor germ cell nuclear factor/retinoid receptor- related testis-associated receptorJournal of Biological Chemistry.  272:10565-10572. 1997
1997 cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 familyGenomics.  41:40-48. 1997
1997 Cloning of the human orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor and its differential regulation during embryonal carcinoma cell differentiationJournal of Molecular Endocrinology.  18:167-176. 1997
1997 Differential expression of human cornifin α and β in squamous differentiating epithelial tissues and several skin lesionsJournal of Investigative Dermatology.  108:200-204. 1997
1997 Epidermal differentiation and squamous metaplasia: From stem cell to cell deathJournal of Dermatology.  24:711-725. 1997
1997 Hair cycle-associated changes in splenocyte proliferation 1997
1997 Production of POMC, CRH-R1, MC1, and MC2 receptor mRNA and expression of tyrosinase gene in relation to hair cycle and dexamethasone treatment in the C57BL/6 mouse skinJournal of Investigative Dermatology.  108:160-165. 1997
1997 The role of p27(Kip1) in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cellsOncogene.  14:2111-2122. 1997
1996 Ultraviolet B stimulus production of corticotropin releasing factor (CRF) by human melanocytesFEBS Letters.  399:175-176. 1996
1996 Suppression by retinoids of the induction of the CCAAT/enhancer-binding protein α and the nuclear receptors PPARγ and RORγ during adipocyte differentiation of 3T3-L1 cellsMolecular and cellular differentiation.  4:365-381. 1996
1996 Cloning of a cDNA encoding the murine orphan receptor RZR/RORγ and characterization of its response elementGene.  181:199-206. 1996
1996 Interferon-γ as a regulator of squamous differentiationJournal of Dermatological Science.  13:98-106. 1996
1996 Regulation of cornifin α expression in the vaginal and uterine epithelium by estrogen and retinoic acidMolecular and Cellular Endocrinology.  123:7-15. 1996
1996 Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: Regulation by ultraviolet B 1996
1996 ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skinJournal of Clinical Endocrinology and Metabolism.  81:2746-2749. 1996
1996 ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin.Journal of Clinical Endocrinology and Metabolism.  81:2746-2749. 1996
1996 Transplantable melanomas in gerbils (Meriones unguiculatus). I. Origin, morphology and growth rate 1996
1996 The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin 1996
1996 Regulation of retinoid-induced differentiation in embryonal carcinoma PCC4.aza1R cells: Effects of retinoid-receptor selective ligandsMolecular Cancer Research.  7:327-337. 1996
1996 Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARα-mediated increase of type II transglutaminaseBlood.  87:1939-1950. 1996
1996 γ-Interferon induces an irreversible growth arrest in mid-G1 in mammary epithelial cells which correlates with a block in hyperphosphorylation of retinoblastomaMolecular Cancer Research.  7:289-300. 1996
1996 Cloning and regulation of cornifin β, a new member of the cornifin/spr family: Suppression by retinoic acid receptor-selective retinoidsJournal of Biological Chemistry.  271:3737-3742. 1996
1996 Correspondence re: G. P. Studzinski and D. C. Moore, Sunlight - Can it prevent as well as cause cancer? Cancer Res., 55: 4014-4022, 1995Cancer Research.  56:925. 1996
1996 Localization and expression of cornifin-α/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasmsJournal of Investigative Dermatology.  106:647-654. 1996
1996 Metabolism of serotonin to n-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin cultureJournal of Biological Chemistry.  271:12281-12286. 1996
1996 Pharmacological disruption of hair follicle pigmentation by cyclophosphamide as a model for studying the melanocyte response to and recovery from cytotoxic drug damage in situJournal of Investigative Dermatology.  106:1203-1211. 1996
1996 Potential mechanism of skin response to stressInternational Journal of Dermatology.  35:849-851. 1996
1995 Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skinFEBS Letters.  374:113-116. 1995
1995 Cloning of the gene encoding the murine orphan receptor TAK1 and cell-type-specific expression in testisGene.  163:239-242. 1995
1995 The Orphan Receptor TAK1 Acts as a Repressor of RAR-, RXR- and T3R-Mediated Signaling PathwaysBiochemical and Biophysical Research Communications.  211:83-91. 1995
1995 RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testisGene.  152:247-251. 1995
1995 Choriocarcinoma presenting as a cutaneous metastasisJournal of Cutaneous Pathology.  22:374-377. 1995
1995 Cutaneous melanoma: Pathology, relevant prognostic indicators and progressionBritish Medical Bulletin.  51:548-569. 1995
1995 Evidence for the involvement of retinoic acid receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoidsJournal of Biological Chemistry.  270:6022-6029. 1995
1995 Identification and characterization of a novel squamous cell-associated gene related to PMP22Journal of Biological Chemistry.  270:28910-28916. 1995
1995 Identification of a transposon-related RNA down-regulated by retinoic acid in embryonal carcinoma and embryonic stem cellsExperimental Cell Research.  221:294-300. 1995
1995 Modification of late epidermal differentiation in photoaged skin treated with topical retinoic acid cream 1995
1995 Retinoic acid nuclear receptor β inhibits breast carcinoma anchorage independent growthJournal of Cellular Physiology.  165:449-458. 1995
1995 Ultraviolet B and melanocyte-stimulating hormone (MSH) stimulate mRNA production for αMSH receptors and proopiomelanocortin-derived peptides in mouse melanoma cells and transformed keratinocytesJournal of Investigative Dermatology.  105:655-659. 1995
1994 ROR-γ: The Third Member of ROR/RZR Orphan Receptor Subfamily That Is Highly Expressed in Skeletal MuscleBiochemical and Biophysical Research Communications.  205:1976-1983. 1994
1994 Retinoid-resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoidsJournal of Biological Chemistry.  269:21440-21447. 1994
1994 Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon γ: Antagonism by retinoic acid and transforming growth factor β1Journal of Biological Chemistry.  269:2016-2022. 1994
1994 Differential responsiveness of human bronchial epithelial cells, lung carcinoma cells, and bronchial fibroblasts to interferon-gamma in vitro.American Journal of Respiratory Cell and Molecular Biology.  11:147-152. 1994
1994 Inhibition of melanogenesis for melanoma therapy?Journal of Investigative Dermatology.  103:742. 1994
1994 Mast cell involvement in murine hair growthDevelopmental Biology.  163:230-240. 1994
1994 Melanogenesis during the anagen-catagen-telogen transformation of the murine hair cycleJournal of Investigative Dermatology.  102:862-869. 1994
1994 Murine skin as a target for melatonin bioregulationExperimental Dermatology.  3:45-50. 1994
1994 TAK1: Molecular cloning and characterization of a new member of the nuclear receptor superfamily 1994
1994 Towards defining receptors for l-tyrosine and l-DOPAMolecular and Cellular Endocrinology.  99. 1994
1993 Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? 1993
1993 Regulation of proliferation-specific and differentiation-specific genes during senescence of human epidermal keratinocyte and mammary epithelial cellsBiochemical and Biophysical Research Communications.  197:46-54. 1993
1993 Melanogenesis is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth.Journal of Investigative Dermatology.  101:90S-97S. 1993
1993 Bomirski melanomas: A versatile and powerful model for pigment cell and melanoma research. (Review)International Journal of Oncology.  2:221-228. 1993
1993 Characterization of a hamster melanoma-associated ganglioside antigen as 7-O-acetylated disialoganglioside GD3Journal of Lipid Research.  34:1565-1572. 1993
1993 Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin 1993
1993 Enhanced Growth Potential of Cultured Rahbit Tracheal Epithelial Cells Following Exposure to N‐Methyl‐N′‐nitro‐N‐nitrosoguanidineCancer Science.  84:1113-1119. 1993
1993 Estrogen receptor‐negative breast cancer cells transfected with the estrogen receptor exhibit increased RARα gene expression and sensitivity to growth inhibition by retinoic acidJournal of Cellular Biochemistry.  53:394-404. 1993
1993 Expression of cornifin in squamous differentiating epithelial tissues, including psoriatic and retinoic acid-treated skinJournal of Investigative Dermatology.  101:268-274. 1993
1993 Identification and characterization of two isozymic forms of arylamine n-acetyltransferase in syrian hamster skinJournal of Investigative Dermatology.  101:660-665. 1993
1993 Melanocytes as "sensory" and regulatory cells in the epidermisJournal of Theoretical Biology.  164:103-120. 1993
1993 Melanogenesis is coupled to murine anagen: Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growthJournal of Investigative Dermatology.  101. 1993
1993 Melatonin inhibits proliferation and melanogenesis in rodent melanoma cellsExperimental Cell Research.  206:189-194. 1993
1993 On the potential role of proopiomelanocortin in skin physiology and pathologyMolecular and Cellular Endocrinology.  93. 1993
1993 Regulation of transglutaminase type I expression in squamous differentiating rabbit tracheal epithelial cells and human epidermal keratinocytes: Effects of retinoic acid and phorbol esters 1993
1993 Retinoid regulation of human ectocervical epithelial cell transglutaminase activity and keratin gene expressionDifferentiation.  54:219-225. 1993
1992 Cornifin, a cross-linked envelope precursor in keratinocytes that is down- regulated by retinoids 1992
1992 Skin histoculture assay for studying the hair cycleIn vitro cellular & developmental biology : journal of the Tissue Culture Association.  28:695-698. 1992
1992 DOPA inhibits induced proliferative activity of murine and human lymphocytes 1992
1992 L-Dopa binding sites in rodent melanoma cells 1992
1992 Retinoic acid receptors as regulators of human epidermal keratinocyte differentiation 1992
1992 Characterization of the PML-RARa Chimeric Product of the Acute Promyelocytic Leukemia-specific t(15;17) TranslocationCancer Research.  52:3687-3692. 1992
1992 Control of squamous differentiation in tracheobronchial and epidermal epithelial cells: role of retinoids. 1992
1992 Defect of insulin receptor in insulin-resistant variants of cloudman S91 mouse melanoma cells 1992
1992 Expression of a preprorelaxin-like gene during squamous differentiation of rabbit tracheobronchial epithelial cells and its suppression by retinoic acid.Molecular Cancer Research.  3:549-556. 1992
1992 Expression of keratinocyte transglutamine mRNA revealed by in situ hybridizationJournal of Investigative Dermatology.  98:364-368. 1992
1992 Homeobox 1.3 expression: induction by retinoic acid in human bronchial fibroblasts.American Journal of Respiratory Cell and Molecular Biology.  7:3-9. 1992
1992 Hyperplasia and squamous metaplasia in the tracheobronchial epithelium: Alterations in the balance of growth and differentiation factorsAdvances in Experimental Medicine and Biology.  320:89-93. 1992
1992 Identification of a new squamous cell differentiation marker and its suppression by retinoidsJournal of Cellular Physiology.  151:94-102. 1992
1992 L‐DOPA Inhibits In Vitro Phosphorylation of Melanoma GlycoproteinsPigment Cell and Melanoma Research.  5:396-399. 1992
1992 Melanotropic activity of gamma MSH peptides in melanoma cellsLife Sciences.  50:1103-1108. 1992
1992 Proopiomelanocortin expression in the skin during induced hair growth in miceCellular and Molecular Life Sciences.  48:50-54. 1992
1992 Regulation of type I and type II transglutaminase in normal human bronchial epithelial and lung carcinoma cells.American Journal of Respiratory Cell and Molecular Biology.  7:10-18. 1992
1992 Retinoid Antagonism of Estrogen-responsive Transforming Growth Factor a and pS2 Gene Expression in Breast Carcinoma CellsCancer Research.  52:3938-3945. 1992
1991 POMC gene expression in mouse and hamster melanoma cellsFEBS Letters.  291:165-168. 1991
1991 Retinoylation of cytokeratins in normal human epidermal keratinocytesBiochemical and Biophysical Research Communications.  180:393-400. 1991
1991 L-tyrosine-binding proteins on melanoma cells.In vitro cellular & developmental biology : journal of the Tissue Culture Association.  27A:735-738. 1991
1991 L-tyrosine induces tyrosinase expression via a posttranscriptional mechanismCellular and Molecular Life Sciences.  47:721-724. 1991
1991 On the putative mechanism of induction and regulation of melanogenesis by L-tyrosineActa Dermato-Venereologica.  71:150-152. 1991
1991 Analysis of Fv-1 restriction in two murine embryonal carcinoma cell lines and a series of differentiated derivativesJournal of General Virology.  72:609-616. 1991
1991 Can some melanotropins modulate keratinocyte proliferation?Journal of Investigative Dermatology.  97:747. 1991
1991 Differential expression and activity of melanogenesis-related proteins during induced hair growth in miceJournal of Investigative Dermatology.  96:172-179. 1991
1991 Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cellsExperimental Cell Research.  195:163-170. 1991
1991 Growth and differentiation factors in tracheobronchial epitheliumAmerican Journal of Physiology.  260. 1991
1991 Induction of extracellular matrix gene expression in normal human keratinocytes by transforming growth factor β is altered by cellular differentiationExperimental Cell Research.  193:93-100. 1991
1991 L-tyrosine-binding proteins on melanoma cellsIn vitro cellular & developmental biology : journal of the Tissue Culture Association.  27:735-738. 1991
1991 Molecular mechanism of tyrosinase regulation by L-DOPA in hamster melanoma cellsLife Sciences.  48:2075-2079. 1991
1991 Molecular mechanisms governing melanogenesis in hamster melanomas: Relative abundance of tyrosinase and catalase-B (gp 75) 1991
1991 Pro‐opiomelanocortin Expression and Potential Function of Pro‐opiomelanocortin Products during Induced Hair Growth in MiceAnnals of the New York Academy of Sciences.  642:459-461. 1991
1991 Ultrastructural immunohistochemical localization of clara cell secretory protein in pulmonary epithelium of rabbitsEnvironmental Health Perspectives.  93:225-232. 1991
1990 Primary structure of keratinocyte transglutaminase 1990
1990 Regulation of transglutaminase Type II by transforming growth factor-β1 in normal and transformed human epidermal keratinocytesJournal of Biological Chemistry.  265:11098-11104. 1990
1990 Secretion of a platelet-derived growth factor homologue by rat alveolar macrophages exposed to particulates in vitroEuropean Journal of Cell Biology.  51:327-334. 1990
1990 Are L-tyrosine and L-dopa hormone-like bioregulators?Journal of Theoretical Biology.  143:123-138. 1990
1990 Down-regulation of squamous cell-specific markers by retinoids: Transglutaminase type I and cholesterol sulfotransferaseMethods in Enzymology.  190:42-49. 1990
1990 Expression of nuclear retinoic acid receptors in wild-type and mutant embryonal carcinoma PCC4.aza1R cells.Molecular Cancer Research.  1:535-542. 1990
1990 Inhibition of growth and squamous‐cell differentiation markers in cultured human head and neck squamous carcinoma cells by β‐all‐trans retinoic acidInternational Journal of Cancer.  45:195-202. 1990
1990 Isolation and binding characteristics of nuclear retinoic acid receptorsMethods in Enzymology.  189:248-255. 1990
1990 Multi-stage program of differentiation in human epidermal keratinocytes: Regulation by retinoidsJournal of Investigative Dermatology.  95. 1990
1989 Glycosphingolipids in Bomirski Transplantable Melanomas in HamstersCancer Research.  49:7051-7056. 1989
1989 L-Tyrosine stimulates induction of tyrosinase activity by MSH and reduces cooperative interactions between MSH receptors in hamster melanoma cells 1989
1989 Effects of Bryostatins and Retinoic Acid on Phorbol Ester- and Diacylglycerol-induced Squamous Differentiation in Human Tracheobronchial Epithelial CellsCancer Research.  49:3990-3995. 1989
1989 Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids.Journal of Medicinal Chemistry.  32:1504-1517. 1989
1989 Squamous differentiation in normal and transformed rat tracheal epithelial cellsCarcinogenesis.  10:743-748. 1989
1989 Action of phorbol esters, bryostatins, and retinoic acid on cholesterol sulfate synthesis: Relation to the multistep process of differentiation in human epidermal keratinocytesJournal of Investigative Dermatology.  93:108-115. 1989
1989 Arachidonic acid metabolism in normal and transformed rat tracheal epithelial cells and its possible role in the regulation of cell proliferationExperimental Lung Research.  15:391-408. 1989
1989 Differential Expression of Fv‐1 in Fibroblasts Derived from Embryonal Carcinoma CellsAnnals of the New York Academy of Sciences.  567:280-281. 1989
1989 Effect of substratum and retinoids upon the mucosecretory differentiation of airway epithelial cells in vitroEnvironmental Health Perspectives.  80:229-237. 1989
1989 Hypothesis: Possible role for the melatonin receptor in vitiligo: Discussion paperJournal of the Royal Society of Medicine.  82:539-541. 1989
1989 Identification and characterization of nuclear retinoic acid-binding activity in human myeloblastic leukemia HL-60 cells 1989
1989 In vitro and in vivo growth and differentiation of clones of tracheal basal cellsAmerican Journal of Pathology.  134:539-549. 1989
1989 Increased cholesterol sulfate and cholesterol sulfotransferase activity in relation to the multi-step process of differentiation in human epidermal keratinocytesJournal of Investigative Dermatology.  92:203-209. 1989
1989 Keratin 13 expression is linked to squamous differentiation in rabbit tracheal epithelial cells and down-regulated by retinoic acidExperimental Cell Research.  182:622-634. 1989
1989 L-tyrosine induces synthesis of melanogenesis related proteinsLife Sciences.  45:1799-1803. 1989
1989 L‐Tyrosine, L‐DOPA, and Tyrosinase as Positive Regulators of the Subcellular Apparatus of Melanogenesis in Bomirski Ab Amelanotic Melanoma CellsPigment Cell and Melanoma Research.  2:109-116. 1989
1989 MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesisJournal of Cell Science.  92:551-559. 1989
1989 Multistep process of squamous differentiation in tracheobronchial epithelial cells in vitro: Analogy with epidermal differentiationEnvironmental Health Perspectives.  80:149-160. 1989
1989 Persistence of abnormal chloride conductance regulation in transformed cystic fibrosis epitheliaScience.  244:1472-1475. 1989
1989 Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoidsMolecular and Cellular Biology.  9:4846-4851. 1989
1988 The natural history of a family of transplantable melanomas in hamstersCancer and Metastasis Reviews.  7:95-118. 1988
1988 A possible role for melanin precursors in regulating both pigmentation and proliferation of melanocytes.Progress in clinical and biological research.  256:143-154. 1988
1988 Cholesterol Sulfate Accumulation in Tumorigenic and Nontumorigenic Rat Esophageal Epithelial Cells: Evidence for Defective Differentiation Control in Tumorigenic CellsCancer Research.  48:5289-5295. 1988
1988 Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, L-tyrosine and L-dopaJournal of Cell Science.  89:287-296. 1988
1988 Regulation of Melanogenesis in MelanocytesPigment Cell and Melanoma Research.  1:79-87. 1988
1988 Retinoids, growth factors, and the tracheobronchial epitheliumLaboratory Investigation.  59:1-4. 1988
1988 Teratogenicity of benzoic acid derivatives of retinoic acid in cultured mouse embryosReproductive Toxicology.  2:91-98. 1988
1988 The differentiation potential of tracheal basal cellsLaboratory Investigation.  58:706-717. 1988
1987 Increase in cholesterol sulfotransferase activity during in vitro squamous differentiation of rabbit tracheal epithelial cells and its inhibition by retinoic acidJournal of Biological Chemistry.  262:13069-13074. 1987
1987 MSH binding in bomirski amelanotic hamster melanoma cells is stimulated by L-tyrosine 1987
1987 Metabolism of all-trans-retinol and all-trans-retinoic acid in rabbit tracheal epithelial cells in culture 1987
1987 Retinoic acid and substratum regulate the differentiation of rabbit tracheal epithelial cells into squamous and secretory phenotype. Morphological and biochemical characterizationLaboratory Investigation.  56:654-664. 1987
1987 Biologic and biochemical characterization of a macrophage-derived growth factor for rat lung fibroblastsChest.  91:15s-16s. 1987
1987 Human bronchial epithelial cells synthesize cholesterol sulfate during squamous differentiation in vitroJournal of Cellular Physiology.  133:573-578. 1987
1987 Molecular cloning of gene sequences regulated during squamous differentiation of tracheal epithelial cells and controlled by retinoic acidMolecular and Cellular Biology.  7:4017-4023. 1987
1987 Multistep process of squamous differentiation of tracheobronchial epithelial cells: Role of retinoidsDermatologica.  175:37-44. 1987
1987 New Benzoic Acid Derivatives with Retinoid Activity: Lack of Direct Correlation between Biological Activity and Binding to Cellular Retinoic Acid Binding ProteinCancer Research.  47:3523-3527. 1987
1987 Pathology and ultrastructural characteristics of a hypomelanotic variant of transplantable hamster melanoma with elevated tyrosinase activityJournal of Investigative Dermatology.  89:469-473. 1987
1987 Purification, characterization and proteinase-inhibitory activity of a Clara-cell secretory protein from the pulmonary extracellular lining of rabbits.Biochemical Journal.  248:337-344. 1987
1987 Regulation of differentiation of airway epithelial cellsChest.  91:22s-23s. 1987
1987 Repopulation of denuded tracheas by clara cells isolated from the lungs of rabbitsExperimental Lung Research.  12:311-329. 1987
1987 Synthesis of mucous glycoproteins by rabbit tracheal cells in vitro. Modulation by substratum, retinoids and cyclic AMPBiochemical Journal.  242:19-25. 1987
1987 The differentiation capacity of Clara cells isolated from the lungs of rabbitsLaboratory Investigation.  57:219-229. 1987
1986 Accumulation of cholesterol 3-sulfate during in vitro squamous differentiation of rabbit tracheal epithelial cells and its regulation by retinoidsJournal of Biological Chemistry.  261:13898-13904. 1986
1986 Characterization of transglutaminase activity in rabbit tracheal epithelial cells. Regulation by retinoidsJournal of Biological Chemistry.  261:15097-15101. 1986
1986 Ultrastructural aspects of melanization of hamster Ab amelanotic melanoma in primary cell cultureActa Dermato-Venereologica.  66:520-523. 1986
1986 Action of retinoic acid on the diacylglycerol-induced ornithine decarboxylase activity, reduction in EGF binding and protein kinase C activation in rat tracheal epithelial 2C5 cellsExperimental Cell Research.  166:519-525. 1986
1986 Biosynthesis and release of proteins by isolated pulmonary clara cellsExperimental Lung Research.  11:277-294. 1986
1986 Differential response to retinoic acid of Syrian hamster embryo fibroblasts expressing v-src or v-Ha-ras oncogenes.Molecular and Cellular Biology.  6:3341-3348. 1986
1986 Regulation of differentiation of airway epithelial cells by retinoidsBiochemical Society Transactions.  14:930-933. 1986
1986 Regulation of proliferation and differentiation of respiratory tract epithelial cells by TGFβExperimental Cell Research.  167:539-549. 1986
1985 Metabolic characterization of three hamster melanoma variantsNeoplasma.  32:593-598. 1985
1985 Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding 1985
1985 Phenotypic changes of Ab hamster melanoma during long-term culture. 1985
1985 Retinoic acid and 12-O-tetradecanoylphorbol-13-acetate alter release of glycoproteins from mouse fibroblast BALB/C 3T6 cellsCarcinogenesis.  6:337-342. 1985
1985 Some properties of Bomirski Ab amelanotic melanoma cells, which underwent spontaneous melanization in primary cell culture - Growth kinetics, cell morphology, melanin content and tumorigenicityJournal of Cancer Research and Clinical Oncology.  109:29-37. 1985
1985 Action of retinoic acid on keratin expression by epithelial cells of the rabbit trachea in culture 1985
1985 Action of retinoic acid on the expression of the transformed phenotype in Syrian hamster embryo cells containing different oncogenes 1985
1985 Biochemical characterization of mucous glycoproteins synthesized and secreted by hamster tracheal epithelial cells in primary cultureJournal of Biological Chemistry.  260:4021-4027. 1985
1985 Biosynthesis and release of proteins by isolated Clara cells and other cells of the pulmonary epithelium 1985
1985 Inhibition of ornithine decarboxylase by retinoic acid and difluoromethylornithine in relation to their effects on differentiation and proliferationExperimental Cell Research.  156:221-230. 1985
1985 Production of insulin‐like growth factor‐II (MSA) by endoderm‐like cells derived from embryonal carcinoma cells: Possible mediator of embryonic cell growthJournal of Cellular Physiology.  124:199-206. 1985
1985 Regulation of differentiation of tracheal epithelial cells by retinoids.Novartis Foundation symposium.  113:61-76. 1985
1985 Retinoids antagonize the induction of ornithine decarboxylase activity by phorbol esters and phospholipase C in rat tracheal epithelial cellsJournal of Cellular Physiology.  123:386-394. 1985
1984 Effect of tissue selection on melanization of MI hamster melanoma.Neoplasma.  31:551-556. 1984
1984 Effects of actinomycin D and cycloheximide on the increase in tyrosinase activity of hamster amelanotic 1984
1984 Interaction of epidermal growth factor with basal and differentiating epidermal cells of mice resistant and sensitive to carcinogenesisCarcinogenesis.  5:735-740. 1984
1984 Biochemical characterization of mucin secreted by hamster tracheal cells in primary culture 1984
1984 Biochemical characterization of three hamster melanoma variants-I. Tyrosinase activity and melanin content 1984
1984 Biochemical characterization of three hamster melanoma variants-II. Glycolysis and oxygen consumption 1984
1984 Hamster tracheal mucin secreted in vitro contains poly-n- acetyllactosamine oligosaccharides 1984
1984 Modulation of cell growth by retinoids and their possible mechanisms of action 1984
1983 Induction of differentiation of embryonal carcinoma cells by retinol: Possible mechanismsBiochemical and Biophysical Research Communications.  114:593-599. 1983
1983 Action of epidermal growth factor and retinoids on anchorage-dependent and-independent growth of nontransformed rat kidney cellsCancer Research.  43:2094-2099. 1983
1983 A new differentiated cell line (Dif 5) derived by retinoic acid treatment of F9 teratocarcinoma cells capable of extracellular matrix production and growth in the absence of serumExperimental Cell Research.  147:315-327. 1983
1983 Action of Retinoids on the Anchorage-independent Growth of Normal Rat Kidney Fibroblasts Induced by 12- O-Tetradecanoylphorbol-13-acetate or Sarcoma Growth FactorCancer Research.  43:68-72. 1983
1983 Bloom's syndrome cells have an abnormal serum growth responseExperimental Cell Research.  145:381-388. 1983
1983 Production of insulin-like growth factor by DIF 5 endoderm cells: Possible early embryonic growth hormoneCell Biology International.  7:563. 1983
1983 Rapid melanization of bomirski amelanotic melanoma cells in cell culture 1983
1983 The role of NADP-dependent dehydrogenases in hydroxylation of tyrosine in hamster melanomaNeoplasma.  30:239-243. 1983
1983 Transplantability of Bomirski melanomas in Syrian hamstersNeoplasma.  30:51-56. 1983
1983 Tyrosinase activity in primary cell culture of amelanotic melanoma cells 1983
1982 Susceptibility determinants for mouse epidermal carcinogenesis.IARC scientific publications.  259-268. 1982
1982 Effects of retinoic acid on the binding and mitogenic activity of epidermal growth factorJournal of Cellular Physiology.  110:235-240. 1982
1982 Enhancement in 'apparent' membrane microviscosity during differentiation of embryonal carcinoma cells induced by retinoidsExperimental Cell Research.  138:494-498. 1982
1982 Studies on antagonistic actions of TPA and retinoic acid.Carcinogenesis; a comprehensive survey.  7:513-518. 1982
1981 Antagonism between retinoids and phorbol esters 1981
1981 Retinoids modulate the responses to various growth factors in normal rat kidney fibroblasts 1981
1980 Retinoids specifically enhance the number of epidermal growth factor receptorsNature.  284:626-629. 1980
1980 Relationship between Binding Affinities to Cellular Retinoic Acid-binding Protein and in Vivo and in Vitro Properties for 18 RetinoidsCancer Research.  40:212-220. 1980
1979 Possible role of retinoic acid binding protein in retinoid stimulation of embryonal carcinoma cell differentiation [20]Nature.  278:180-182. 1979
1979 Characterization of the action of retinoids on mouse fibroblast cell linesExperimental Cell Research.  119:289-299. 1979
1979 Analyses of cell surface and secreted proteins of primary cultures of mouse extraembryonic membranesDevelopmental Biology.  70:89-104. 1979
1979 Stimulation of differentiation of several murine embryonal carcinoma cell lines by retinoic acidExperimental Cell Research.  124:381-391. 1979
1976 Effects of colicins K and E1 on the glucose phosphotransferase system 1976
1975 Energy requirement for the initiation of colicin action in Escherichia coli 1975
1974 Effects of colicin K on a mutant of Escherichia coli deficient in Ca2+,Mg2+ activated adenosine triphosphataseJournal of Biological Chemistry.  249:6138-6143. 1974
1974 Characteristics of the killing effect of a Staphylococcus epidermidis bacteriocin. 1974
1973 Effects of colicin A and staphylococcin 1580 on amino acid uptake into membrane vesicles of Escherichia coli and staphylococcus aureus. 1973
1973 Characterization and extrachromosomal control of bacteriocin production in Staphylococcus aureus.Antimicrobial Agents and Chemotherapy.  4:49-57. 1973
1972 Mode of action of a Staphylococcus epidermidis bacteriocin.Antimicrobial Agents and Chemotherapy.  2:456-463. 1972


Year Title Altmetric
2001 The ROR nuclear orphan receptor subfamily: Critical regulators of multiple biological processes.  Ed. 69.  2001
2000 The peripheral myelin protein 22 and epithelial membrane protein family.  Ed. 64.  2000
1999 Cutaneous Neuroimmunomodulation: The Proopiomelanocortin System, New York Academy of Sciences, Munster, Germany, 11-13 September 1998: The proopiomelanocortin system in cutaneous neuroimmunomodulation. An introductory overview.  Ed. 885.  1999


Year Title Altmetric
2020 The role of classical and novel forms of vitamin d in the pathogenesis and progression of nonmelanoma skin cancers.  257-283. 2020
2019 Analysis of the transcriptional activity of retinoic acid-related orphan receptors (RORs) and inhibition by inverse agonists.  193-202. 2019
2018 Regulation of squamous differentiation in tracheobronchial epithelial cells by synthetic Retinoids.  287-306. 2018
2011 Evidence of skin field cancerization.  317-370. 2011
2011 Synthesis and metabolism of melatonin in the skin and retinal pigment epithelium.  69-80. 2011

Education And Training

  • Doctor of Philosophy in Biology / Biological Sciences, 1983
  • Doctor of Medicine, 1979
  • Full Name

  • Andrzej Slominski