• Dr. Arynchyn has been an integral part of the Coronary Artery Risk Development in Young Adults (CARDIA) study since 2004 (17 years). He has led the preparation and implementation of the Year 20 (Y20), Y25, Y30, and Y35 study visits. He is responsible for the design and development of study data collection forms, quality control (QC) documentation, manual of operations (MOO), study protocols, and other essential documents. He oversees all quality assurance (QA)/QC procedures associated with all CARDIA components, including exams, participant follow-up, and endpoints. He designs follow-up and endpoints forms, reports, and other documentation. He provides CARDIA subcommittees with all required information and prepares reports for the Steering Committee and NHLBI Observational Study Monitoring Board meetings. His support of the CARDIA study is essential for continuing study success and funding.

    Dr. Arynchyn has served as Principal Investigator for the CARDIA Coordinating Center for several ancillary and sub-studies such as Oxidative Stress and Early Atherosclerosis (YALTA), Brain MRI, Pulmonary function decline, and Cystatin C and Chronic Kidney Disease and Cardiovascular Complications. Currently, he is the Principal Investigator for the CARDIA Lung Function ancillary study. Dr. Arynchyn also served as a Deputy Director for the Dental Practice-Based Research Network (DPBRN) Coordinating Center.

    Dr. Arynchyn has a unique ability to work on the edge of different sciences. An example is his knowledge of relational computer databases in association with medical and epidemiological data. He leads and provides IT personnel with detailed guidance for the design, development, and programming of numerous reports and data tables that reflect CARDIA data.

    Dr. Arynchyn utilizes his analytical and statistical skills to analyze research data and prepare scientific publications and presentations. His main research activity is focused on pulmonary function changes in the CARDIA cohort in association with different behavioral factors and medical conditions. He participated in numerous American Thoracic Society (ATS) meetings, presenting his research findings. Due to his initiative, ATS dedicated one of its scientific sessions to the presentation of CARDIA pulmonary data. Overall, he has more than 200 publications and presentations in various scientific journals and conferences.

    Dr. Arynchyn’s combined scientific and medical knowledge in different research areas make him a unique and valuable member of many scientific communities. Currently, he participates in the public health program for folate food fortification initiated by Children’s of Alabama and the UAB Department of Pediatric Neurosurgery. His experience in international collaboration with the World Health Organization, the European Union, and the Universities of Italy, Sweden, and Poland makes him an immensely valuable researcher who can generate decision-making suggestions. Dr. Arynchyn has invaluable experience in working with governmental organizations in translating research findings into legislation that improves public health. His leading role as a scientist and Principal Investigator of the International Iodine Deficiency Project made it possible to establish an iodine food fortification program as a state law in Belarus.

    Dr. Arynchyn has unique expertise. He previously served as Chief of the Pediatric Research Laboratory of the Belarus Institute for Radiation Medicine for many years while working on the Chernobyl catastrophe. He also held the position of Deputy Director for Clinical Research for that institution with more than two hundred scientists and staff under his leadership. His previous leadership roles make him an invaluable asset to the UAB Division of Preventive Medicine. He has excellent communication skills and leadership abilities to organize and lead teams of researchers in achieving scientific goals. He can develop and formulate scientific goals and tasks, define required research efforts, and analyze and present scientific data. His critical style of thinking and deep analytical skills helps him to identify any potential hidden issues within a project, and he can correct those issues using his knowledge, experience, and skills in different research areas.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2017 Rapid decline in lung function is temporally associated with greater metabolically active adiposity in a longitudinal study of healthy adults.Thorax.  72:1113-1120. 2017
    2017 Rapid decline in lung function in healthy adults predicts incident excess urinary albumin excretion later in lifeBMJ Open Respiratory Research.  4. 2017
    2015 Quality Control and Reproducibility in M-Mode, Two-Dimensional, and Speckle Tracking Echocardiography Acquisition and Analysis: The CARDIA Study, Year 25 Examination ExperienceEchocardiography: a journal of cardiovascular ultrasound and allied techniques.  32:1233-1240. 2015
    2015 Loss of Lung Health from Young Adulthood and Cardiac Phenotypes in Middle Age.American Journal of Respiratory and Critical Care Medicine.  192:76-85. 2015
    2014 Left atrial dimension and traditional cardiovascular risk factors predict 20-year clinical cardiovascular events in young healthy adults: The CARDIA studyEHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging.  15:893-899. 2014
    2013 Adult-onset asthma becomes the dominant phenotype among women by age 40 years: The longitudinal CARDIA studyAnnals of the American Thoracic Society.  10:188-197. 2013
    2010 Spirometry guidelines influence lung function results in a longitudinal study of young adultsRespiratory Medicine.  104:858-864. 2010
    2010 Lung Function in Young Adults Predicts Airflow Obstruction 20 Years LaterAmerican Journal of Medicine.  123. 2010
    2009 Obesity-asthma association: Is it explained by systemic oxidant stress?Chest.  136:1055-1062. 2009
    2009 Racial differences in incident heart failure among young adultsNew England Journal of Medicine.  360:1179-1190. 2009
    1997 Iodine Deficiency in Belarusian Children as a Possible Factor Stimulating the Irradiation of the Thyroid Gland during the Chernobyl CatastropheEnvironmental Health Perspectives.  105:1487-1487. 1997

    Research Overview

  • • Epidemiology of cardiovascular diseases and risk factors in young adults
    • Pulmonary function and diseases in young adults
    • Health effects of long term radiation and other environmental exposure in children (Chernobyl accident)
    • Iodine deficiency in children and adolescents and associated thyroid disorders
    • Iodine deficiency elimination
    • Prevention of neural tube defects (NTD) using food (flour and salt) fortification with folic acid
  • Education And Training

  • National Institute of Radiological Sciences, Other
  • Radiation Effects Research Foundation, Other
  • World Health Organization, Other
  • University of Alabama at Birmingham Department of Medicine, Postdoctoral Fellowship
  • Doctorate Level Degree in Environmental Health, 2001
  • Doctor of Medicine in Pediatrics Residency Program, 1980
  • Full Name

  • Alexander Arynchyn