Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease.  Nature Communications.  11. 2020
2020 Effects of exercise on sleep in neurodegenerative disease.  Neurobiology of Disease.  140. 2020
2020 Reply to: Exercise for “Sleep Rehabilitation” in Parkinson's Disease.  Movement Disorders.  35:1286. 2020
2020 Randomized, Controlled Trial of Exercise on Objective and Subjective Sleep in Parkinson's Disease.  Movement Disorders.  35:947-958. 2020
2020 Does restless legs syndrome impact cognitive function via sleep quality in adults with Parkinson’s disease?.  International Journal of Neuroscience.  130:322-329. 2020
2020 Practical Evaluation and Management of Insomnia in Parkinson's Disease: A Review.  Movement Disorders Clinical Practice.  7:250-266. 2020
2019 Basic clinical features do not predict dopamine transporter binding in idiopathic REM behavior disorder.  npj Parkinson's Disease.  5. 2019
2019 Feasibility and utility of a clinician dashboard from wearable and mobile application Parkinson’s disease data.  npj Digital Medicine.  2. 2019
2019 Motor phenotype classification in moderate to advanced PD in BioFIND study.  Parkinsonism and Related Disorders.  65:178-183. 2019
2019 Self-reported physical activity levels and clinical progression in early Parkinson's disease.  Parkinsonism and Related Disorders.  61:118-125. 2019
2019 Widespread tau-specific CD4 T cell reactivity in the general population.  Journal of Immunology.  203:84-92. 2019
2018 The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort.  Annals of Clinical and Translational Neurology.  5:1460-1477. 2018
2018 Deep brain stimulation and sleep-wake disturbances in parkinson disease: A review.  Frontiers in Neurology.  9. 2018
2018 Transform with no Parameters Based on Extrema Points for Non-stationary Signal Analysis 2018
2018 Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features.  Movement Disorders.  33:282-288. 2018
2018 Effects of Exercise on Non-motor Symptoms in Parkinson's Disease 2018
2017 High-intensity exercise acutely increases substantia nigra and prefrontal brain activity in parkinson’s disease 2017
2017 Pedestrian safety in patients with Parkinson's disease: A case-control study.  Movement Disorders.  32:1748-1755. 2017
2017 Longitudinal assessment of excessive daytime sleepiness in early Parkinson's disease.  Journal of Neurology, Neurosurgery and Psychiatry.  88:653-662. 2017
2017 Treatment of Sleep Dysfunction in Parkinson’s Disease.  Current Treatment Options in Neurology.  19. 2017
2017 The effect of unilateral subthalamic nucleus deep brain stimulation on depression in Parkinson's disease.  Brain Stimulation.  10:651-656. 2017
2017 Effects of Subthalamic Nucleus Deep Brain Stimulation on Objective Sleep Outcomes in Parkinson's Disease.  Movement Disorders Clinical Practice.  4:183-190. 2017
2016 The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort.  Movement Disorders.  31:924-932. 2016
2016 Refractory status epilepticus and glutamic acid decarboxylase antibodies in adults: Presentation, treatment and outcomes 2016
2016 Longitudinal changes in cognition in early Parkinson's disease patients with REM sleep behavior disorder.  Parkinsonism and Related Disorders.  27:102-106. 2016
2015 Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study.  Movement Disorders.  30:1371-1381. 2015
2015 Prevalence and characteristics of tremor in the NARCOMS multiple sclerosis registry: A cross-sectional survey.  BMJ Open.  5. 2015
2013 The relationship between clinical phenotype and early staged bilateral deep brain stimulation in Parkinson disease: Clinical article.  Journal of Neurosurgery.  119:1530-1536. 2013
2013 Metabolomics and the search for biomarkers in Parkinson's disease.  Movement Disorders.  28:1620-1621. 2013
2012 Unilateral subthalamic nucleus deep brain stimulation improves sleep quality in Parkinson's disease.  Parkinsonism and Related Disorders.  18:63-68. 2012
2011 Challenges in diagnosis of isolated central nervous system vasculitis.  Brain and Behavior.  1:57-61. 2011
2004 Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes.  Oncogene.  23:2330-2338. 2004
2003 Characterization of p73 functional domains necessary for transactivation and growth suppression.  Oncogene.  22:4333-4347. 2003
2003 Isolation and characterization of fourteen novel putative and nine known target genes of the p53 family.  Cancer Biology and Therapy.  2:56-63. 2003
2002 The promise and obstacle of p53 as a cancer therapeutic agent.  Current Molecular Medicine.  2:329-345. 2002
1999 The biochemical role of glutamine 188 in human galactose-1-phosphate uridyltransferase.  Journal of Biological Chemistry.  274:6559-6566. 1999

Chapter

Year Title Altmetric
2015 Impact of surgical therapies on sleep and alertness in Parkinson’s disease.  195-207. 2015

Principal Investigator On

  • The Parkinson’s Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2020 - 2033
  • Adaptive Immunity in the Etiology and Progression of Parkinson’s disease  awarded by LA JOLLA INSTITUTE FOR IMMUNOLOGY 2020 - 2021
  • A Dose Selection Trial of Light Therapy for Impaired Sleep in Parkinson's Disease  awarded by MASSACHUSETTS GENERAL HOSPITAL 2019 - 2021
  • Development of T Cell-Based Biomarkers for Autoimmunity in Parkinson's Disease  awarded by LA JOLLA INSTITUTE FOR IMMUNOLOGY 2020 - 2021
  • Private Grant  awarded by LILLY USA, LLC 2018 - 2020
  • Development of T Cell-Based Biomarkers for Autoimmunity in Parkinson's Disease  awarded by LA JOLLA INSTITUTE FOR IMMUNOLOGY 2018 - 2019
  • Private Grant  awarded by JAZZ PHARMACEUTICALS, INC. 2018 - 2019
  • Private Grant  awarded by AXOVANT SCIENCES, INC. - NEW 2017 - 2019
  • The Systemic Synuclein Sampling Study (S4)  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2015 - 2018
  • Private Grant  awarded by AXOVANT SCIENCES, INC. - NEW 2016 - 2018
  • Clinician-input Study: How the Fox Wearable Companion Mobile Application can Influence Treatment and Care (CIS-PD)  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2017 - 2018
  • Impact of a Novel Exercise Intervention on Executive Function and Sleep in Patients with Parkinson's Disease  awarded by Parkinson's Disease Foundation 2017 - 2018
  • The Effect of Low Frequency STN DBS on Sleep and Vigilance in PD Patients  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2012 - 2017
  • Fox Investigation for New Discovery of Biomarkers (BioFIND)  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2014 - 2015
  • The Effects of Lower and High Frequency Unilateral STN DBS on Sleep in Parkinson's Disease  awarded by American Sleep Medicine Foundation 2011 - 2012

    • Investigator On

  • Sleep for Stroke Management and Recovery Trial (Sleep SMART) Stroke Trial  awarded by University of Cincinnati 2018 - 2024
  • The Parkinson's Progression Marker's Initiative (PPMI)  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2010 - 2023
  • Innate and Adaptive Immunity in Parkinson Disease  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2018 - 2023
  • Innate and Adaptive Immunity in Parkinson Disease - Core B: Clinical Research Core  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2018 - 2023
  • Innate and Adaptive Immunity in Parkinson Disease - Project 5: Innate and Adaptive Immunity in Lewy Body Dementia  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2018 - 2023
  • Interactions of Gut Microbiome, Genetic Susceptibility and Environmental Factors in Parkinson's Disease  awarded by DOD - Department of Defense 2018 - 2022
  • UAB Research and Education Program in Neuroscience  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2017 - 2022
  • A Randomized, Double-Blind, Placebo-Controlled, Phase IIa, Parallel Group, Two-Cohort Study to Define the Safety, Tolerability, Clinical and Exploratory Biological Activity of the Chronic Administration of Nilotinib in Participants with Parkinson’s Disease (PD)  awarded by Northwestern University 2018 - 2022
  • Sleep and Circadian Research Core (SCRC)  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2019 - 2021
  • Private Grant  awarded by BIOGEN IDEC, INC. 2018 - 2021
  • Private Grant  awarded by F.Hoffmann-La Roche Ltd. 2017 - 2021
  • Center for Translational Research on Aging and Mobility  awarded by National Institute on Aging/NIH/DHHS 2014 - 2021
  • Center for Translational Research on Aging and Mobility - Core B: Pilot Core  awarded by National Institute on Aging/NIH/DHHS 2014 - 2021
  • Restless Legs Syndrome and Physical Activity in Adults With Multiple Sclerosis  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2019 - 2021
  • Private Grant  awarded by FUSION HEALTH LLC 2019 - 2020
  • Mechanisms of Refractory Hypertension  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2018 - 2020
  • The Edmond J. Safra Visiting Nurse Faculty Program at the Parkinson Disease Foundation  awarded by National Parkinson Foundation, Inc. 2017 - 2019
  • Phase 3 Trial of Inosine for Parkinson's Disease CCC  awarded by MASSACHUSETTS GENERAL HOSPITAL 2015 - 2019
  • SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)  awarded by MASSACHUSETTS GENERAL HOSPITAL 2015 - 2019
  • Post-Stroke Aphasia and rTMS Treatment (PART) Study  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2012 - 2018
  • Private Grant  awarded by SERINA THERAPEUTICS ^ 2015 - 2017
  • Private Grant  awarded by ABBVIE INC 2012 - 2016
  • Private Grant  awarded by PHARMA TWO B. LTD 2014 - 2015
  • Private Grant  awarded by Solvay Pharmaceuticals, Inc. 2010 - 2014
  • Private Grant  awarded by IMPAX LABORATORIES, INC. 2012 - 2013

    • Education And Training

  • University of Alabama at Birmingham, Postdoctoral Fellowship
  • Doctor of Medicine, Medical College of Georgia 2005
  • Doctor of Philosophy, Medical College of Georgia 2003
  • Bachelor's Degree in Medicine, Agnes Scott College 1998
  • UAB Hospital, Internship 2006
  • UAB Hospital, Residency 2009
  • UAB Hospital, Postdoctoral Fellowship 2011
  • UAB Hospital, Postdoctoral Fellowship 2010

    • Full Name

  • Amy Amara