| Year |
Title |
Altmetric |
| 2021
|
Bile Acids Gate Dopamine Transporter Mediated Currents
2021
|
|
| 2021
|
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease.
JCI insight.
6.
2021
|
|
| 2021
|
A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster.
Molecular Psychiatry.
26:4417-4430.
2021
|
|
| 2021
|
Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
eLife.
10.
2021
|
|
| 2021
|
Autism-Associated Variant in the SLC6A3 Gene Alters the Oral Microbiome and Metabolism in a Murine Model.
Frontiers in Psychiatry.
12.
2021
|
|
| 2021
|
The dopamine transporter gene SLC6A3: multidisease risks.
Molecular Psychiatry.
2021
|
|
| 2020
|
A novel mouse model of glucagon-like peptide-1 receptor expression: A look at the brain.
Journal of Comparative Neurology.
528:2445-2470.
2020
|
|
| 2020
|
Glucagon-like peptide-1 receptor regulation of basal dopamine transporter activity is species-dependent
2020
|
|
| 2019
|
GLP-1: Molecular mechanisms and outcomes of a complex signaling system
2019
|
|
| 2019
|
Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.
Journal of Clinical Investigation.
129:3407-3419.
2019
|
|
| 2019
|
Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3
2019
|
|
| 2018
|
Glucagon-like peptide 1 signaling inhibits allergen-induced lung IL-33 release and reduces group 2 innate lymphoid cell cytokine production in vivo.
Journal of Allergy and Clinical Immunology.
142:1515-1528.e8.
2018
|
|
| 2018
|
Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward.
PLoS Biology.
16.
2018
|
|
| 2018
|
Brief exposure to obesogenic diet disrupts brain dopamine networks.
PLoS ONE.
13.
2018
|
|
| 2017
|
Gβγ 3 subunit activation promotes dopamine efflux through the dopamine transporter.
Molecular Psychiatry.
22:1673-1679.
2017
|
|
| 2017
|
Atypical dopamine efflux caused by 3,4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter.
Journal of Chemical Neuroanatomy.
83-84:69-74.
2017
|
|
| 2016
|
Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels.
Translational Psychiatry.
6:e809.
2016
|
|
| 2015
|
Insights in how amphetamine ROCKs (Rho-associated containing kinase) membrane protein trafficking
2015
|
|
| 2015
|
The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice.
Physiology and Behavior.
149:262-268.
2015
|
|
| 2015
|
Dual agonist occupancy of at 1 -R-α 2C -AR heterodimers results in atypical G s -PKA signaling.
Nature Chemical Biology.
11:271-279.
2015
|
|
| 2015
|
Zn2+ reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder.
Molecular Autism.
6.
2015
|
|
| 2015
|
Rare Autism-Associated Variants Implicate Syntaxin 1 (STX1 R26Q) Phosphorylation and the Dopamine Transporter (hDAT R51W) in Dopamine Neurotransmission and Behaviors.
EBioMedicine.
2:135-146.
2015
|
|
| 2015
|
Impaired mTORC2 signaling in catecholaminergic neurons exaggerates high fat diet-induced hyperphagia.
Heliyon.
1.
2015
|
|
| 2015
|
mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission
2015
|
|
| 2014
|
Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery.
ACS Chemical Neuroscience.
5:943-951.
2014
|
|
| 2014
|
Missense dopamine transporter mutations associate with adult parkinsonism and ADHD.
Journal of Clinical Investigation.
124:3107-3120.
2014
|
|
| 2014
|
Moving beyond energy homeostasis: New roles for glucagon-like peptide-1 in food and drug reward
2014
|
|
| 2014
|
Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function
2014
|
|
| 2014
|
PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.
Nature Chemical Biology.
10:582-589.
2014
|
|
| 2014
|
SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking.
Translational Psychiatry.
4:e464.
2014
|
|
| 2013
|
De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder.
Molecular Psychiatry.
18:1315-1323.
2013
|
|
| 2013
|
Drosophila melanogaster: A novel animal model for the behavioral characterization of autism-associated mutations in the dopamine transporter gene.
Molecular Psychiatry.
18:1235.
2013
|
|
| 2013
|
GLP-1 analog attenuates cocaine reward.
Molecular Psychiatry.
18:961-962.
2013
|
|
| 2013
|
Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate
2013
|
|
| 2013
|
Structural arrangement of the intracellular Ca2+ binding domains of the cardiac Na+/Ca2+ exchanger (NCX1.1): Effects of Ca2+ binding.
Journal of Biological Chemistry.
288:4194-4207.
2013
|
|
| 2012
|
Phosphatidylinositol 4,5-biphosphate (PIP2) lipids regulate the phosphorylation of syntaxin N-terminus by modulating both its position and local structure.
Biochemistry.
51:7685-7698.
2012
|
|
| 2012
|
Exendin-4 decreases amphetamine-induced locomotor activity.
Physiology and Behavior.
106:574-578.
2012
|
|
| 2012
|
Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation
2012
|
|
| 2012
|
Rescue of dopamine transporter function in hypoinsulinemic rats by a D 2 receptor-ERK-dependent mechanism
2012
|
|
| 2011
|
Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons.
Neuron.
72:977-990.
2011
|
|
| 2011
|
Erratum: Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT (Nature Neuroscience (2011) 14 (469-477)).
Nature Neuroscience.
14:1617.
2011
|
|
| 2011
|
Insulin signaling and addiction.
Neuropharmacology.
61:1123-1128.
2011
|
|
| 2011
|
Impaired striatal akt signaling disrupts dopamine homeostasis and increases feeding.
PLoS ONE.
6.
2011
|
|
| 2011
|
Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT.
Nature Neuroscience.
14:469-477.
2011
|
|
| 2011
|
Insulin regulation of monoamine signaling: Pathway to obesity.
Neuropsychopharmacology.
36:359-360.
2011
|
|
| 2010
|
Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis
2010
|
|
| 2010
|
Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression.
ACS Chemical Neuroscience.
1:476-481.
2010
|
|
| 2010
|
Molecular mechanisms of amphetamine actions in caenorhabditis elegans.
Molecular Pharmacology.
78:151-156.
2010
|
|
| 2010
|
Rab11 supports amphetamine-stimulated norepinephrine transporter trafficking
2010
|
|
| 2010
|
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenialike behaviors in neuronal rictor null mice.
PLoS Biology.
8.
2010
|
|
| 2010
|
Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder
2010
|
|
| 2009
|
Subcellular localization of the antidepressant-sensitive norepinephrine transporter.
BMC Neuroscience.
10.
2009
|
|
| 2009
|
A juxtamembrane mutation in the n terminus of the dopamine transporter induces preference for an inward-facing conformation.
Molecular Pharmacology.
75:514-524.
2009
|
|
| 2009
|
A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters.
Molecular Neurobiology.
39:73-80.
2009
|
|
| 2008
|
Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux.
Molecular Pharmacology.
74:1101-1108.
2008
|
|
| 2008
|
Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats
2008
|
|
| 2008
|
PI3K signaling supports amphetamine-induced dopamine efflux.
Biochemical and Biophysical Research Communications.
372:656-661.
2008
|
|
| 2008
|
Anomalous dopamine release associated with a human dopamine transporter coding variant
2008
|
|
| 2008
|
Behavioral effects of amphetamine in streptozotocin-treated rats
2008
|
|
| 2008
|
Currents in response to rapid concentration jumps of amphetamine uncover novel aspects of human dopamine transporter function
2008
|
|
| 2007
|
Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine.
PLoS Biology.
5:2369-2378.
2007
|
|
| 2007
|
Evidence for D2 receptor mediation of amphetamine-induced normalization of locomotion and dopamine transporter function in hypoinsulinemic rats.
Journal of Neurochemistry.
101:151-159.
2007
|
|
| 2007
|
Dopamine transporter activity mediates amphetamine-induced inhibition of Akt through a Ca2+/calmodulin-dependent kinase II-dependent mechanism.
Molecular Pharmacology.
71:835-842.
2007
|
|
| 2007
|
Insulin replacement restores the behavioral effects of quinpirole and raclopride in streptozotocin-treated rats.
Journal of Pharmacology and Experimental Therapeutics.
320:1216-1223.
2007
|
|
| 2007
|
Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1a/transporter complexes.
Molecular Pharmacology.
71:230-239.
2007
|
|
| 2006
|
Calmodulin Kinase II Interacts with the Dopamine Transporter C Terminus to Regulate Amphetamine-Induced Reverse Transport.
Neuron.
51:417-429.
2006
|
|
| 2006
|
Regulation of dopamine transporter trafficking by intracellular amphetamine.
Molecular Pharmacology.
70:542-548.
2006
|
|
| 2006
|
The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current.
Neuropharmacology.
50:354-361.
2006
|
|
| 2006
|
The dopamine transporter: A vigilant border control for psychostimulant action.
Handbook of Experimental Pharmacology.
175:215-232.
2006
|
|
| 2005
|
Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine.
Journal of Neurochemistry.
94:1402-1410.
2005
|
|
| 2005
|
Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution.
Molecular Pharmacology.
68:102-109.
2005
|
|
| 2005
|
Mechanisms of neurotransmitter release by amphetamines: A review.
Progress in Neurobiology.
75:406-433.
2005
|
|
| 2005
|
Amphetamine induces dopamine efflux through a dopamine transporter channel
2005
|
|
| 2005
|
Biogenic amine neurotransmitter transporters: Just when you thought you knew them
2005
|
|
| 2004
|
N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux.
PLoS Biology.
2.
2004
|
|
| 2004
|
Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter.
Molecular Pharmacology.
66:137-143.
2004
|
|
| 2004
|
Amphetamine regulation of dopamine transport: Combined measurements of transporter currents and transporter imaging support the endocytosis of an active carrier.
Journal of Biological Chemistry.
279:8966-8975.
2004
|
|
| 2003
|
Regulation of dopamine transporter function and plasma membrane expression by dopamine, amphetamine, and cocaine
2003
|
|
| 2003
|
Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity
2003
|
|
| 2003
|
Amphetamine-induced dopamine efflux: A voltage-sensitive and intracellular Na+-dependent mechanism.
Journal of Biological Chemistry.
278:12070-12077.
2003
|
|
| 2003
|
Dopamine transport currents are promoted from curiosity to physiology.
Trends in Neurosciences.
26:173-176.
2003
|
|
| 2003
|
Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats
2003
|
|
| 2003
|
A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity
2003
|
|
| 2002
|
Cerulein-induced acute pancreatitis in the rat is significantly ameliorated by treatment with MEK1/2 inhibitors U0126 and PD98059.
Pancreas.
25:251-259.
2002
|
|
| 2002
|
PI 3-kinase regulation of dopamine uptake.
Journal of Neurochemistry.
81:859-869.
2002
|
|
| 2002
|
Cocaine increases dopamine uptake and cell surface expression of dopamine transporters.
Biochemical and Biophysical Research Communications.
290:1545-1550.
2002
|
|
| 2000
|
Amphetamine-induced loss of human dopamine transporter activity: An internalization-dependent and cocaine-sensitive mechanism
2000
|
|
| 1999
|
L-proline and L-pipecolate induce enkephalin-sensitive currents in human embryonic kidney 293 cells transfected with the high-affinity mammalian brain L-proline transporter
1999
|
|
| 1998
|
Acute regulation of norepinephrine transport: I. Protein kinase C- linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.
Journal of Pharmacology and Experimental Therapeutics.
287:733-743.
1998
|
|
| 1998
|
Patch-clamp and amperometric recordings from norepinephrine transporters: Channel activity and voltage-dependent uptake
1998
|
|
| 1998
|
Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins.
Biological Psychiatry.
44:169-178.
1998
|
|
| 1998
|
Fluctuation analysis of norepinephrine and serotonin transporter currents.
Methods in Enzymology.
296:578-593.
1998
|
|
| 1997
|
Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel
1997
|
|
| 1997
|
Electrophysiological Analysis of Transporter Function.
Advances in Pharmacology.
42:186-190.
1997
|
|
| 1997
|
Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
1997
|
|
| 1996
|
Norepinephrine transporters have channel modes of conduction
1996
|
|
| 1996
|
Functional role of low-voltage-activated dihydropyridine-sensitive Ca channels during the action potential in adult rat sensory neurones
1996
|
|
| 1995
|
Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants
1995
|
|
| 1994
|
Inactivation of single Ca2+ channels in rat sensory neurons by extracellular Ca2+.
1994
|
|
| 1994
|
Inactivation of L-type Ca channels in embryonic chick ventricle cells: dependence on the cytoskeletal agents colchicine and taxol.
Biophysical Journal.
67:2296-2304.
1994
|
|
| 1992
|
Effect of firing rate on the calcium permeability in adult neurons during spontaneous action potentials.
Biophysical Journal.
63:926-934.
1992
|
|
| |
Bile acids gate dopamine transporter mediated currents
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